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Results: 1 to 20 of 65

1.

In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I.

Zhao Y, Black AS, Bonnet DJ, Maryanoff BE, Curtiss LK, Leman LJ, Ghadiri MR.

J Lipid Res. 2014 Jun 29. pii: jlr.M049262. [Epub ahead of print]

PMID:
24975585
[PubMed - as supplied by publisher]
Free Article
2.

Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis.

Leman LJ, Maryanoff BE, Ghadiri MR.

J Med Chem. 2014 Mar 27;57(6):2169-96. doi: 10.1021/jm4005847. Epub 2013 Oct 29. Review.

PMID:
24168751
[PubMed - indexed for MEDLINE]
3.

Mimicry of high-density lipoprotein: functional peptide-lipid nanoparticles based on multivalent peptide constructs.

Zhao Y, Imura T, Leman LJ, Curtiss LK, Maryanoff BE, Ghadiri MR.

J Am Chem Soc. 2013 Sep 11;135(36):13414-24. doi: 10.1021/ja404714a. Epub 2013 Aug 26.

PMID:
23978057
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Ion channel models based on self-assembling cyclic peptide nanotubes.

Montenegro J, Ghadiri MR, Granja JR.

Acc Chem Res. 2013 Dec 17;46(12):2955-65. doi: 10.1021/ar400061d. Epub 2013 Jul 30. Review.

PMID:
23898935
[PubMed - indexed for MEDLINE]
5.

Macrocyclic peptoid-Peptide hybrids as inhibitors of class I histone deacetylases.

Olsen CA, Montero A, Leman LJ, Ghadiri MR.

ACS Med Chem Lett. 2012 Aug 10;3(9):749-53. doi: 10.1021/ml300162r. eCollection 2012 Sep 13.

PMID:
24900543
[PubMed]
Free PMC Article
6.

Discovery of HDAC Inhibitors That Lack an Active Site Zn(2+)-Binding Functional Group.

Vickers CJ, Olsen CA, Leman LJ, Ghadiri MR.

ACS Med Chem Lett. 2012 Apr 26;3(6):505-8. doi: 10.1021/ml300081u. eCollection 2012 Jun 14.

PMID:
24900500
[PubMed]
Free PMC Article
7.

Self-assembling peptide nanotubes with antiviral activity against hepatitis C virus.

Montero A, Gastaminza P, Law M, Cheng G, Chisari FV, Ghadiri MR.

Chem Biol. 2011 Nov 23;18(11):1453-62. doi: 10.1016/j.chembiol.2011.08.017.

PMID:
22118679
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides that Restore Trafficking and Activity of ΔF508-CFTR.

Hutt DM, Olsen CA, Vickers CJ, Herman D, Chalfant M, Montero A, Leman LJ, Burkle R, Maryanoff BE, Balch WE, Ghadiri MR.

ACS Med Chem Lett. 2011 Jul 21;2(9):703-707.

PMID:
21984958
[PubMed]
Free PMC Article
9.

Real-time monitoring of DNA polymerase function and stepwise single-nucleotide DNA strand translocation through a protein nanopore.

Chu J, González-López M, Cockroft SL, Amorin M, Ghadiri MR.

Angew Chem Int Ed Engl. 2010 Dec 27;49(52):10106-9. doi: 10.1002/anie.201005460. No abstract available.

PMID:
21105031
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic alpha3beta-tetrapeptides.

Olsen CA, Ghadiri MR.

J Med Chem. 2009 Dec 10;52(23):7836-46. doi: 10.1021/jm900850t.

PMID:
19705846
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Dynamic polythioesters via ring-opening polymerization of 1,4-thiazine-2,5-diones.

Ura Y, Al-Sayah M, Montenegro J, Beierle JM, Leman LJ, Ghadiri MR.

Org Biomol Chem. 2009 Jul 21;7(14):2878-84. doi: 10.1039/b903612a. Epub 2009 Jun 8.

PMID:
19582297
[PubMed - indexed for MEDLINE]
12.

Universal translators for nucleic acid diagnosis.

Picuri JM, Frezza BM, Ghadiri MR.

J Am Chem Soc. 2009 Jul 8;131(26):9368-77. doi: 10.1021/ja902490x.

PMID:
19566101
[PubMed - indexed for MEDLINE]
13.

Antibacterial cyclic D,L-alpha-glycopeptides.

Motiei L, Rahimipour S, Thayer DA, Wong CH, Ghadiri MR.

Chem Commun (Camb). 2009 Jul 7;(25):3693-5. doi: 10.1039/b902455g. Epub 2009 May 29.

PMID:
19557251
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Self-assembling sequence-adaptive peptide nucleic acids.

Ura Y, Beierle JM, Leman LJ, Orgel LE, Ghadiri MR.

Science. 2009 Jul 3;325(5936):73-7. doi: 10.1126/science.1174577. Epub 2009 Jun 11.

PMID:
19520909
[PubMed - indexed for MEDLINE]
Free Article
15.

Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides.

Horne WS, Olsen CA, Beierle JM, Montero A, Ghadiri MR.

Angew Chem Int Ed Engl. 2009;48(26):4718-24. doi: 10.1002/anie.200805900.

PMID:
19267380
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues.

Beierle JM, Horne WS, van Maarseveen JH, Waser B, Reubi JC, Ghadiri MR.

Angew Chem Int Ed Engl. 2009;48(26):4725-9. doi: 10.1002/anie.200805901.

PMID:
19266506
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures.

Montero A, Beierle JM, Olsen CA, Ghadiri MR.

J Am Chem Soc. 2009 Mar 4;131(8):3033-41. doi: 10.1021/ja809508f.

PMID:
19239270
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Catalyzed oxidative corrosion of porous silicon used as an optical transducer for ligand-receptor interactions.

Voelcker NH, Alfonso I, Ghadiri MR.

Chembiochem. 2008 Jul 21;9(11):1776-86. doi: 10.1002/cbic.200800119.

PMID:
18576449
[PubMed - indexed for MEDLINE]
19.

Sequence-addressable DNA logic.

Voelcker NH, Guckian KM, Saghatelian A, Ghadiri MR.

Small. 2008 Apr;4(4):427-31. doi: 10.1002/smll.200700113. No abstract available.

PMID:
18350554
[PubMed - indexed for MEDLINE]
20.

A virocidal amphipathic {alpha}-helical peptide that inhibits hepatitis C virus infection in vitro.

Cheng G, Montero A, Gastaminza P, Whitten-Bauer C, Wieland SF, Isogawa M, Fredericksen B, Selvarajah S, Gallay PA, Ghadiri MR, Chisari FV.

Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3088-93. doi: 10.1073/pnas.0712380105. Epub 2008 Feb 19.

PMID:
18287023
[PubMed - indexed for MEDLINE]
Free PMC Article

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