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Results: 1 to 20 of 142

1.

Defective autophagy through epg5 mutation results in failure to reduce germ plasm and mitochondria.

Herpin A, Englberger E, Zehner M, Wacker R, Gessler M, Schartl M.

FASEB J. 2015 Jul 16. pii: fj.14-265462. [Epub ahead of print]

PMID:
26183773
2.

Hey bHLH Proteins Interact with a FBXO45 Containing SCF Ubiquitin Ligase Complex and Induce Its Translocation into the Nucleus.

Salat D, Winkler A, Urlaub H, Gessler M.

PLoS One. 2015 Jun 12;10(6):e0130288. doi: 10.1371/journal.pone.0130288. eCollection 2015.

3.

Multiple mechanisms of MYCN dysregulation in Wilms tumour.

Williams RD, Chagtai T, Alcaide-German M, Apps J, Wegert J, Popov S, Vujanic G, van Tinteren H, van den Heuvel-Eibrink MM, Kool M, de Kraker J, Gisselsson D, Graf N, Gessler M, Pritchard-Jones K.

Oncotarget. 2015 Mar 30;6(9):7232-43.

4.

Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors.

Wegert J, Ishaque N, Vardapour R, Geörg C, Gu Z, Bieg M, Ziegler B, Bausenwein S, Nourkami N, Ludwig N, Keller A, Grimm C, Kneitz S, Williams RD, Chagtai T, Pritchard-Jones K, van Sluis P, Volckmann R, Koster J, Versteeg R, Acha T, O'Sullivan MJ, Bode PK, Niggli F, Tytgat GA, van Tinteren H, van den Heuvel-Eibrink MM, Meese E, Vokuhl C, Leuschner I, Graf N, Eils R, Pfister SM, Kool M, Gessler M.

Cancer Cell. 2015 Feb 9;27(2):298-311. doi: 10.1016/j.ccell.2015.01.002.

PMID:
25670083
5.

Mechanisms of epigenetic and cell-type specific regulation of Hey target genes in ES cells and cardiomyocytes.

Weber D, Heisig J, Kneitz S, Wolf E, Eilers M, Gessler M.

J Mol Cell Cardiol. 2015 Feb;79:79-88. doi: 10.1016/j.yjmcc.2014.11.004. Epub 2014 Nov 13.

PMID:
25446183
6.

Hey bHLH transcription factors.

Weber D, Wiese C, Gessler M.

Curr Top Dev Biol. 2014;110:285-315. doi: 10.1016/B978-0-12-405943-6.00008-7. Review.

PMID:
25248480
7.

The Notch pathway inhibits TGFβ signaling in breast cancer through HEYL-mediated crosstalk.

Han L, Diehl A, Nguyen NK, Korangath P, Teo W, Cho S, Kominsky S, Huso DL, Feigenbaum L, Rein A, Argani P, Landberg G, Gessler M, Sukumar S.

Cancer Res. 2014 Nov 15;74(22):6509-18. doi: 10.1158/0008-5472.CAN-14-0816. Epub 2014 Sep 12.

PMID:
25217524
8.

1q gain is a frequent finding in preoperatively treated Wilms tumors, but of limited prognostic value for risk stratification in the SIOP2001/GPOH trial.

Vokuhl C, Vogelgesang W, Leuschner I, Furtwängler R, Graf N, Gessler M, Dörner E, Pietsch T.

Genes Chromosomes Cancer. 2014 Nov;53(11):960-2. doi: 10.1002/gcc.22203. Epub 2014 Jul 18. No abstract available.

PMID:
25044466
9.

Mosaic variegated aneuploidy in mouse BubR1 deficient embryos and pregnancy loss in human.

Schmid M, Steinlein C, Tian Q, Hanlon Newell AE, Gessler M, Olson SB, Rosenwald A, Kneitz B, Fedorov LM.

Chromosome Res. 2014 Sep;22(3):375-92. doi: 10.1007/s10577-014-9432-x. Epub 2014 Jul 1. Erratum in: Chromosome Res. 2014 Dec;22(4):645-6.

PMID:
24981203
10.

[Adjustable transobturatoric sling system in men : diagnosis and therapy recommendations to persistent pain].

Bauer RM, Hübner W, Knopf HJ, Gessler M, Kugler A, Smorag U.

Urologe A. 2014 Aug;53(8):1175-80. doi: 10.1007/s00120-014-3473-9. German.

PMID:
24824468
11.

GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development.

Stefanovic S, Barnett P, van Duijvenboden K, Weber D, Gessler M, Christoffels VM.

Nat Commun. 2014 Apr 28;5:3680. doi: 10.1038/ncomms4680.

12.

Survival in patients with high-risk prostate cancer is predicted by miR-221, which regulates proliferation, apoptosis, and invasion of prostate cancer cells by inhibiting IRF2 and SOCS3.

Kneitz B, Krebs M, Kalogirou C, Schubert M, Joniau S, van Poppel H, Lerut E, Kneitz S, Scholz CJ, Ströbel P, Gessler M, Riedmiller H, Spahn M.

Cancer Res. 2014 May 1;74(9):2591-603. doi: 10.1158/0008-5472.CAN-13-1606. Epub 2014 Mar 7.

13.

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Borggrefe M, Schimpf R, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kääb S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bézieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R.

Nat Genet. 2013 Sep;45(9):1044-9. doi: 10.1038/ng.2712. Epub 2013 Jul 21. Erratum in: Nat Genet. 2013 Nov;45(11):1409. Borggrefe, Martin [added]; Schimpf, Rainer [added].

14.

COUP-TFII orchestrates venous and lymphatic endothelial identity by homo- or hetero-dimerisation with PROX1.

Aranguren XL, Beerens M, Coppiello G, Wiese C, Vandersmissen I, Lo Nigro A, Verfaillie CM, Gessler M, Luttun A.

J Cell Sci. 2013 Mar 1;126(Pt 5):1164-75. doi: 10.1242/jcs.116293. Epub 2013 Jan 23.

15.

Treatment-independent miRNA signature in blood of Wilms tumor patients.

Schmitt J, Backes C, Nourkami-Tutdibi N, Leidinger P, Deutscher S, Beier M, Gessler M, Graf N, Lenhof HP, Keller A, Meese E.

BMC Genomics. 2012 Aug 7;13:379. doi: 10.1186/1471-2164-13-379.

16.

Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors.

Heisig J, Weber D, Englberger E, Winkler A, Kneitz S, Sung WK, Wolf E, Eilers M, Wei CL, Gessler M.

PLoS Genet. 2012;8(5):e1002728. doi: 10.1371/journal.pgen.1002728. Epub 2012 May 17.

17.

Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1.

Tu X, Chen J, Lim J, Karner CM, Lee SY, Heisig J, Wiese C, Surendran K, Kopan R, Gessler M, Long F.

PLoS Genet. 2012;8(3):e1002577. doi: 10.1371/journal.pgen.1002577. Epub 2012 Mar 22.

18.

Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney.

O'Meara E, Stack D, Lee CH, Garvin AJ, Morris T, Argani P, Han JS, Karlsson J, Gisselson D, Leuschner I, Gessler M, Graf N, Fletcher JA, O'Sullivan MJ.

J Pathol. 2012 May;227(1):72-80. doi: 10.1002/path.3985. Epub 2012 Feb 17.

PMID:
22294382
19.

Autoantibody signature differentiates Wilms tumor patients from neuroblastoma patients.

Schmitt J, Keller A, Nourkami-Tutdibi N, Heisel S, Habel N, Leidinger P, Ludwig N, Gessler M, Graf N, Berthold F, Lenhof HP, Meese E.

PLoS One. 2011;6(12):e28951. doi: 10.1371/journal.pone.0028951. Epub 2011 Dec 16.

20.

Retinoic acid pathway activity in Wilms tumors and characterization of biological responses in vitro.

Wegert J, Bausenwein S, Kneitz S, Roth S, Graf N, Geissinger E, Gessler M.

Mol Cancer. 2011 Nov 8;10:136. doi: 10.1186/1476-4598-10-136.

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