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Results: 1 to 20 of 84


Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index.

Aalbers CJ, Gerlag DM, Vervoordeldonk MJ, Tak PP, Landewé RB.

J Rheumatol. 2015 Jul 15. pii: jrheum.140956. [Epub ahead of print]


Nuclear Factor-κB-inducing Kinase Is Expressed in Synovial Endothelial Cells in Patients with Early Arthritis and Correlates with Markers of Inflammation: A Prospective Cohort Study.

Maijer KI, Noort AR, de Hair MJ, van der Leij C, van Zoest KP, Choi IY, Gerlag DM, Maas M, Tak PP, Tas SW.

J Rheumatol. 2015 Jul 15. pii: jrheum.150245. [Epub ahead of print]


A Clinically Based Protein Discovery Strategy to Identify Potential Biomarkers of Response to Anti-TNF-α Treatment of Psoriatic Arthritis.

Collins ES, Butt AQ, Gibson DS, Dunn MJ, Fearon U, van Kuijk AW, Gerlag DM, Pontifex E, Veale DJ, Tak PP, FitzGerald O, Pennington SR.

Proteomics Clin Appl. 2015 Jun 24. doi: 10.1002/prca.201500051. [Epub ahead of print]


DNA Methylome Signature in Synoviocytes From Patients With Early Rheumatoid Arthritis Compared to Synoviocytes From Patients With Longstanding Rheumatoid Arthritis.

Ai R, Whitaker JW, Boyle DL, Tak PP, Gerlag DM, Wang W, Firestein GS.

Arthritis Rheumatol. 2015 Jul;67(7):1978-80. doi: 10.1002/art.39123. No abstract available.


Preclinical inflammatory rheumatic diseases: an overview and relevant nomenclature.

Raza K, Gerlag DM.

Rheum Dis Clin North Am. 2014 Nov;40(4):569-80. doi: 10.1016/j.rdc.2014.07.001. Epub 2014 Sep 2. Review.


Discovery and confirmation of a protein biomarker panel with potential to predict response to biological therapy in psoriatic arthritis.

Ademowo OS, Hernandez B, Collins E, Rooney C, Fearon U, van Kuijk AW, Tak PP, Gerlag DM, FitzGerald O, Pennington SR.

Ann Rheum Dis. 2014 Sep 3. pii: annrheumdis-2014-205417. doi: 10.1136/annrheumdis-2014-205417. [Epub ahead of print]


From synovial tissue to peripheral blood: myeloid related protein 8/14 is a sensitive biomarker for effective treatment in early drug development in patients with rheumatoid arthritis.

Choi IY, Gerlag DM, Holzinger D, Roth J, Tak PP.

PLoS One. 2014 Aug 28;9(8):e106253. doi: 10.1371/journal.pone.0106253. eCollection 2014.


Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?

van Baarsen LG, Lebre MC, van der Coelen D, Aarrass S, Tang MW, Ramwadhdoebe TH, Gerlag DM, Tak PP.

Arthritis Res Ther. 2014 Aug 22;16(4):426. doi: 10.1186/s13075-014-0426-z.


Clock gene expression in different synovial cells of patients with rheumatoid arthritis and osteoarthritis.

Becker T, Tohidast-Akrad M, Humpeler S, Gerlag DM, Kiener HP, Zenz P, Steiner G, Ekmekcioglu C.

Acta Histochem. 2014 Sep;116(7):1199-207. doi: 10.1016/j.acthis.2014.07.001. Epub 2014 Aug 7.


Citrullination of epithelial neutrophil-activating peptide 78/CXCL5 results in conversion from a non-monocyte-recruiting chemokine to a monocyte-recruiting chemokine.

Yoshida K, Korchynskyi O, Tak PP, Isozaki T, Ruth JH, Campbell PL, Baeten DL, Gerlag DM, Amin MA, Koch AE.

Arthritis Rheumatol. 2014 Oct;66(10):2716-27. doi: 10.1002/art.38750.


Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis.

Greven DE, Cohen ES, Gerlag DM, Campbell J, Woods J, Davis N, van Nieuwenhuijze A, Lewis A, Heasmen S, McCourt M, Corkill D, Dodd A, Elvin J, Statache G, Wicks IP, Anderson IK, Nash A, Sleeman MA, Tak PP.

Ann Rheum Dis. 2014 Jun 16. pii: annrheumdis-2014-205234. doi: 10.1136/annrheumdis-2014-205234. [Epub ahead of print]


Reply: To PMID 24574210.

de Hair MJ, van de Sande MG, Ramwadhdoebe TH, van der Leij C, Maas M, Hansson M, Klareskog L, Landewé R, Serre G, van Schaardenburg D, Gerlag DM, van Baarsen LG, Tak PP.

Arthritis Rheumatol. 2014 Jun;66(6):1683-4. doi: 10.1002/art.38411. No abstract available.


Features of the synovium of individuals at risk of developing rheumatoid arthritis: implications for understanding preclinical rheumatoid arthritis.

de Hair MJ, van de Sande MG, Ramwadhdoebe TH, Hansson M, Landewé R, van der Leij C, Maas M, Serre G, van Schaardenburg D, Klareskog L, Gerlag DM, van Baarsen LG, Tak PP.

Arthritis Rheumatol. 2014 Mar;66(3):513-22. doi: 10.1002/art.38273.


FMS-related tyrosine kinase 3 ligand (Flt3L)/CD135 axis in rheumatoid arthritis.

Ramos MI, Perez SG, Aarrass S, Helder B, Broekstra P, Gerlag DM, Reedquist KA, Tak PP, Lebre MC.

Arthritis Res Ther. 2013;15(6):R209.


MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis.

Choi IY, Gerlag DM, Herenius MJ, Thurlings RM, Wijbrandts CA, Foell D, Vogl T, Roth J, Tak PP, Holzinger D.

Ann Rheum Dis. 2015 Mar;74(3):499-505. doi: 10.1136/annrheumdis-2013-203923. Epub 2013 Dec 2.


Local synovial engagement of angiogenic TIE-2 is associated with the development of persistent erosive rheumatoid arthritis in patients with early arthritis.

van de Sande MG, de Launay D, de Hair MJ, García S, van de Sande GP, Wijbrandts CA, Gerlag DM, Reedquist KA, Tak PP.

Arthritis Rheum. 2013 Dec;65(12):3073-83. doi: 10.1002/art.38128.


Pro-atherogenic lipid changes and decreased hepatic LDL receptor expression by tocilizumab in rheumatoid arthritis.

Strang AC, Bisoendial RJ, Kootte RS, Schulte DM, Dallinga-Thie GM, Levels JH, Kok M, Vos K, Tas SW, Tietge UJ, Müller N, Laudes M, Gerlag DM, Stroes ES, Tak PP.

Atherosclerosis. 2013 Jul;229(1):174-81. doi: 10.1016/j.atherosclerosis.2013.04.031. Epub 2013 May 11.


How to perform and analyse synovial biopsies.

Gerlag DM, Tak PP.

Best Pract Res Clin Rheumatol. 2013 Apr;27(2):195-207. doi: 10.1016/j.berh.2013.03.006. Review.


The cellular composition of lymph nodes in the earliest phase of inflammatory arthritis.

van Baarsen LG, de Hair MJ, Ramwadhdoebe TH, Zijlstra IJ, Maas M, Gerlag DM, Tak PP.

Ann Rheum Dis. 2013 Aug;72(8):1420-4. doi: 10.1136/annrheumdis-2012-202990. Epub 2013 May 9.


Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity.

Doorenspleet ME, Klarenbeek PL, de Hair MJ, van Schaik BD, Esveldt RE, van Kampen AH, Gerlag DM, Musters A, Baas F, Tak PP, de Vries N.

Ann Rheum Dis. 2014 Apr;73(4):756-62. doi: 10.1136/annrheumdis-2012-202861. Epub 2013 Apr 20.

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