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Items: 1 to 20 of 61

1.

The Chemistry of the Noncanonical Cyclic Dinucleotide 2'3'-cGAMP and Its Analogs.

Schwede F, Genieser HG, Rentsch A.

Handb Exp Pharmacol. 2016 Jul 9. [Epub ahead of print]

PMID:
27392950
2.

DNA catabolites in triathletes: effects of supplementation with an aronia-citrus juice (polyphenols-rich juice).

García-Flores LA, Medina S, Cejuela-Anta R, Martínez-Sanz JM, Abellán Á, Genieser HG, Ferreres F, Gil-Izquierdo Á.

Food Funct. 2016 Apr 20;7(4):2084-93. doi: 10.1039/c6fo00252h.

PMID:
27050256
3.

Application of Synthetic Peptide Arrays To Uncover Cyclic Di-GMP Binding Motifs.

Düvel J, Bense S, Möller S, Bertinetti D, Schwede F, Morr M, Eckweiler D, Genieser HG, Jänsch L, Herberg FW, Frank R, Häussler S.

J Bacteriol. 2015 Aug 31;198(1):138-46. doi: 10.1128/JB.00377-15.

4.

Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion.

Schwede F, Chepurny OG, Kaufholz M, Bertinetti D, Leech CA, Cabrera O, Zhu Y, Mei F, Cheng X, Manning Fox JE, MacDonald PE, Genieser HG, Herberg FW, Holz GG.

Mol Endocrinol. 2015 Jul;29(7):988-1005. doi: 10.1210/me.2014-1330. Epub 2015 Jun 10.

5.

Effect of elite physical exercise by triathletes on seven catabolites of DNA oxidation.

Villaño D, Vilaplana C, Medina S, Cejuela-Anta R, Martínez-Sanz JM, Gil P, Genieser HG, Ferreres F, Gil-Izquierdo A.

Free Radic Res. 2015;49(8):973-83. doi: 10.3109/10715762.2015.1025388. Epub 2015 Apr 8.

PMID:
25786325
6.

Structure-guided design of selective Epac1 and Epac2 agonists.

Schwede F, Bertinetti D, Langerijs CN, Hadders MA, Wienk H, Ellenbroek JH, de Koning EJ, Bos JL, Herberg FW, Genieser HG, Janssen RA, Rehmann H.

PLoS Biol. 2015 Jan 20;13(1):e1002038. doi: 10.1371/journal.pbio.1002038. eCollection 2015 Jan.

7.

Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag.

Chepurny OG, Bertinetti D, Diskar M, Leech CA, Afshari P, Tsalkova T, Cheng X, Schwede F, Genieser HG, Herberg FW, Holz GG.

Mol Endocrinol. 2013 Aug;27(8):1267-82. doi: 10.1210/me.2013-1029. Epub 2013 Jun 24.

8.
9.

Binding of regulatory subunits of cyclic AMP-dependent protein kinase to cyclic CMP agarose.

Hammerschmidt A, Chatterji B, Zeiser J, Schröder A, Genieser HG, Pich A, Kaever V, Schwede F, Wolter S, Seifert R.

PLoS One. 2012;7(7):e39848. doi: 10.1371/journal.pone.0039848. Epub 2012 Jul 9.

10.

A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa.

Düvel J, Bertinetti D, Möller S, Schwede F, Morr M, Wissing J, Radamm L, Zimmermann B, Genieser HG, Jänsch L, Herberg FW, Häussler S.

J Microbiol Methods. 2012 Feb;88(2):229-36. doi: 10.1016/j.mimet.2011.11.015. Epub 2011 Dec 8.

PMID:
22178430
11.

Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription.

Huseby S, Gausdal G, Keen TJ, Kjærland E, Krakstad C, Myhren L, Brønstad K, Kunick C, Schwede F, Genieser HG, Kleppe R, Døskeland SO.

Cell Death Dis. 2011 Dec 8;2:e237. doi: 10.1038/cddis.2011.124.

12.

Activation of PDE10 and PDE11 phosphodiesterases.

Jäger R, Russwurm C, Schwede F, Genieser HG, Koesling D, Russwurm M.

J Biol Chem. 2012 Jan 6;287(2):1210-9. doi: 10.1074/jbc.M111.263806. Epub 2011 Nov 21.

13.

Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells.

Leech CA, Dzhura I, Chepurny OG, Kang G, Schwede F, Genieser HG, Holz GG.

Prog Biophys Mol Biol. 2011 Nov;107(2):236-47. doi: 10.1016/j.pbiomolbio.2011.07.005. Epub 2011 Jul 19. Review.

14.

Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides.

Werner K, Schwede F, Genieser HG, Geiger J, Butt E.

Naunyn Schmiedebergs Arch Pharmacol. 2011 Aug;384(2):169-76. doi: 10.1007/s00210-011-0662-6. Epub 2011 Jun 29.

15.

Epac-Rap signaling reduces cellular stress and ischemia-induced kidney failure.

Stokman G, Qin Y, Genieser HG, Schwede F, de Heer E, Bos JL, Bajema IM, van de Water B, Price LS.

J Am Soc Nephrol. 2011 May;22(5):859-72. doi: 10.1681/ASN.2010040423. Epub 2011 Apr 14.

16.

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans.

Dzhura I, Chepurny OG, Leech CA, Roe MW, Dzhura E, Xu X, Lu Y, Schwede F, Genieser HG, Smrcka AV, Holz GG.

Islets. 2011 May-Jun;3(3):121-8. Epub 2011 May 1.

17.

Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes.

Christian F, Szaszák M, Friedl S, Drewianka S, Lorenz D, Goncalves A, Furkert J, Vargas C, Schmieder P, Götz F, Zühlke K, Moutty M, Göttert H, Joshi M, Reif B, Haase H, Morano I, Grossmann S, Klukovits A, Verli J, Gáspár R, Noack C, Bergmann M, Kass R, Hampel K, Kashin D, Genieser HG, Herberg FW, Willoughby D, Cooper DM, Baillie GS, Houslay MD, von Kries JP, Zimmermann B, Rosenthal W, Klussmann E.

J Biol Chem. 2011 Mar 18;286(11):9079-96. doi: 10.1074/jbc.M110.160614. Epub 2010 Dec 22.

18.

Cyclic nucleotides as affinity tools: phosphorothioate cAMP analogues address specific PKA subproteomes.

Hanke SE, Bertinetti D, Badel A, Schweinsberg S, Genieser HG, Herberg FW.

N Biotechnol. 2011 Jul;28(4):294-301. doi: 10.1016/j.nbt.2010.12.001. Epub 2010 Dec 13.

PMID:
21147280
19.

Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM.

Kelley GG, Chepurny OG, Schwede F, Genieser HG, Leech CA, Roe MW, Li X, Dzhura I, Dzhura E, Afshari P, Holz GG.

Islets. 2009 Nov-Dec;1(3):260-5. doi: 10.4161/isl.1.3.9645.

20.

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

Jäger R, Schwede F, Genieser HG, Koesling D, Russwurm M.

Br J Pharmacol. 2010 Dec;161(7):1645-60. doi: 10.1111/j.1476-5381.2010.00977.x.

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