Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.
Gastroenterology. 2010.
PMID: 20060832
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Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.
Rauch A, Kutalik Z, Descombes P, Cai T, Di Iulio J, Mueller T, Bochud M, Battegay M, Bernasconi E, Borovicka J, Colombo S, Cerny A, Dufour JF, Furrer H, Günthard HF, Heim M, Hirschel B, Malinverni R, Moradpour D, Müllhaupt B, Witteck A, Beckmann JS, Berg T, Bergmann S, Negro F, Telenti A, Bochud PY; Swiss Hepatitis C Cohort Study; Swiss HIV Cohort Study.
Rauch A, et al.
Gastroenterology. 2010 Apr;138(4):1338-45, 1345.e1-7. doi: 10.1053/j.gastro.2009.12.056. Epub 2010 Jan 11.
Gastroenterology. 2010.
PMID: 20060832
BACKGROUND & AIMS: Hepatitis C virus (HCV) induces chronic infection in 50% to 80% of infected persons; approximately 50% of these do not respond to therapy. We performed a genome-wide association study to screen for host genetic determinant …
BACKGROUND & AIMS: Hepatitis C virus (HCV) induces chronic infection in 50% to 80% of infected persons; approximately 50% of these do no …
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[Genome-wide association study on and the clinical application to chronic hepatitis C].
Sugiyama M, Mizokami M.
Sugiyama M, et al.
Uirusu. 2011 Jun;61(1):15-24. doi: 10.2222/jsv.61.15.
Uirusu. 2011.
PMID: 21972552
Free article.
Review.
Japanese.
Based on the data and technology generated in previous international projects, such as the Human Genome Project and the HapMap, for the building of the common patterns of genetic variation in humans, a genome-wide association study …
Based on the data and technology generated in previous international projects, such as the Human Genome Project and the HapMap, for t …
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Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C.
Trépo E, Pradat P, Potthoff A, Momozawa Y, Quertinmont E, Gustot T, Lemmers A, Berthillon P, Amininejad L, Chevallier M, Schlué J, Kreipe H, Devière J, Manns M, Trépo C, Sninsky J, Wedemeyer H, Franchimont D, Moreno C.
Trépo E, et al.
Hepatology. 2011 Jul;54(1):60-9. doi: 10.1002/hep.24350.
Hepatology. 2011.
PMID: 21488075
Only 20% of patients with chronic hepatitis C (CHC) will develop cirrhosis, and fibrosis progression remains highly unpredictable. A recent genome-wide association study identified a genetic variant in the patatin-like phosp …
Only 20% of patients with chronic hepatitis C (CHC) will develop cirrhosis, and fibrosis progression remains highly unp …
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Interleukin- 28B: a prognostic marker in interferon based therapy of chronic HCV patients of the Pakistan with variable treatment response.
Resham S, Manzoor S, Imran M, Saalim M, Naseem S, Azam S.
Resham S, et al.
APMIS. 2015 Sep;123(9):765-71. doi: 10.1111/apm.12414. Epub 2015 Jul 14.
APMIS. 2015.
PMID: 26177560
In 2009, a genome wide association study (GWAS) revealed that genetic variants in close proximity to the IL28B (IFNL3) gene predicted greater likelihood of achieving sustained virological response (SVR) following treatment with peg …
In 2009, a genome wide association study (GWAS) revealed that genetic variants in close proximity to the …
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