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Results: 1 to 20 of 21

1.

Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity.

Longo KA, Govek EK, Nolan A, McDonagh T, Charoenthongtrakul S, Giuliana DJ, Morgan K, Hixon J, Zhou C, Kelder B, Kopchick JJ, Saunders JO, Navia MA, Curtis R, DiStefano PS, Geddes BJ.

J Pharmacol Exp Ther. 2011 Oct;339(1):115-24. doi: 10.1124/jpet.111.183764. Epub 2011 Jul 20. Erratum in: J Pharmacol Exp Ther. 2012 Mar;340(3):810.

PMID:
21775475
[PubMed - indexed for MEDLINE]
Free Article
2.

Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps.

Qi Y, Longo KA, Giuliana DJ, Gagne S, McDonagh T, Govek E, Nolan A, Zou C, Morgan K, Hixon J, Saunders JO, Distefano PS, Geddes BJ.

BMC Physiol. 2011 Jan 6;11:1. doi: 10.1186/1472-6793-11-1.

PMID:
21211044
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The 24-hour respiratory quotient predicts energy intake and changes in body mass.

Longo KA, Charoenthongtrakul S, Giuliana DJ, Govek EK, McDonagh T, Distefano PS, Geddes BJ.

Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R747-54. doi: 10.1152/ajpregu.00476.2009. Epub 2009 Dec 16.

PMID:
20018821
[PubMed - indexed for MEDLINE]
Free Article
4.

Daily energy balance in growth hormone receptor/binding protein (GHR -/-) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency.

Longo KA, Berryman DE, Kelder B, Charoenthongtrakul S, Distefano PS, Geddes BJ, Kopchick JJ.

Growth Horm IGF Res. 2010 Feb;20(1):73-9. doi: 10.1016/j.ghir.2009.08.002. Epub 2009 Sep 10.

PMID:
19747867
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Enhanced gastrointestinal motility with orally active ghrelin receptor agonists.

Charoenthongtrakul S, Giuliana D, Longo KA, Govek EK, Nolan A, Gagne S, Morgan K, Hixon J, Flynn N, Murphy BJ, Hernández AS, Li J, Tino JA, Gordon DA, DiStefano PS, Geddes BJ.

J Pharmacol Exp Ther. 2009 Jun;329(3):1178-86. doi: 10.1124/jpet.108.150193. Epub 2009 Feb 27.

PMID:
19252061
[PubMed - indexed for MEDLINE]
Free Article
6.

Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice.

Longo KA, Charoenthongtrakul S, Giuliana DJ, Govek EK, McDonagh T, Qi Y, DiStefano PS, Geddes BJ.

Regul Pept. 2008 Oct 9;150(1-3):55-61. doi: 10.1016/j.regpep.2008.03.011. Epub 2008 Mar 30.

PMID:
18453014
[PubMed - indexed for MEDLINE]
7.

Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan.

DiStefano PS, Curtis R, Geddes BJ.

Curr Alzheimer Res. 2007 Apr;4(2):153-7. Review.

PMID:
17430240
[PubMed - indexed for MEDLINE]
8.

The prolactin-releasing peptide receptor (GPR10) regulates body weight homeostasis in mice.

Gu W, Geddes BJ, Zhang C, Foley KP, Stricker-Krongrad A.

J Mol Neurosci. 2004;22(1-2):93-103.

PMID:
14742914
[PubMed - indexed for MEDLINE]
9.

Adenovirus-mediated expression of human prorelaxin promotes the invasive potential of canine mammary cancer cells.

Silvertown JD, Geddes BJ, Summerlee AJ.

Endocrinology. 2003 Aug;144(8):3683-91.

PMID:
12865351
[PubMed - indexed for MEDLINE]
10.

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing.

Wang L, Manji GA, Grenier JM, Al-Garawi A, Merriam S, Lora JM, Geddes BJ, Briskin M, DiStefano PS, Bertin J.

J Biol Chem. 2002 Aug 16;277(33):29874-80. Epub 2002 May 17.

PMID:
12019269
[PubMed - indexed for MEDLINE]
Free Article
11.

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis.

Razmara M, Srinivasula SM, Wang L, Poyet JL, Geddes BJ, DiStefano PS, Bertin J, Alnemri ES.

J Biol Chem. 2002 Apr 19;277(16):13952-8. Epub 2002 Jan 30.

PMID:
11821383
[PubMed - indexed for MEDLINE]
Free Article
12.

PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B.

Manji GA, Wang L, Geddes BJ, Brown M, Merriam S, Al-Garawi A, Mak S, Lora JM, Briskin M, Jurman M, Cao J, DiStefano PS, Bertin J.

J Biol Chem. 2002 Mar 29;277(13):11570-5. Epub 2002 Jan 10.

PMID:
11786556
[PubMed - indexed for MEDLINE]
Free Article
13.

Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis.

Geddes BJ, Wang L, Huang WJ, Lavellee M, Manji GA, Brown M, Jurman M, Cao J, Morgenstern J, Merriam S, Glucksmann MA, DiStefano PS, Bertin J.

Biochem Biophys Res Commun. 2001 Jun 1;284(1):77-82.

PMID:
11374873
[PubMed - indexed for MEDLINE]
14.

Assessing viral gene therapy in neuroendocrine models.

Geddes BJ, Harding TC, Lightman SL, Uney JB.

Front Neuroendocrinol. 1999 Oct;20(4):296-316. Review.

PMID:
10569280
[PubMed - indexed for MEDLINE]
15.

Overexpression of hsp70i facilitates reactivation of intracellular proteins in neurones and protects them from denaturing stress.

Beaucamp N, Harding TC, Geddes BJ, Williams J, Uney JB.

FEBS Lett. 1998 Dec 18;441(2):215-9.

PMID:
9883887
[PubMed - indexed for MEDLINE]
Free Article
16.

Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system.

Harding TC, Geddes BJ, Murphy D, Knight D, Uney JB.

Nat Biotechnol. 1998 Jun;16(6):553-5.

PMID:
9624686
[PubMed - indexed for MEDLINE]
17.

Tetracycline-regulated transgene expression in hippocampal neurones following transfection with adenoviral vectors.

Harding TC, Geddes BJ, Noel JD, Murphy D, Uney JB.

J Neurochem. 1997 Dec;69(6):2620-3.

PMID:
9375698
[PubMed - indexed for MEDLINE]
18.

Long-term gene therapy in the CNS: reversal of hypothalamic diabetes insipidus in the Brattleboro rat by using an adenovirus expressing arginine vasopressin.

Geddes BJ, Harding TC, Lightman SL, Uney JB.

Nat Med. 1997 Dec;3(12):1402-4.

PMID:
9396613
[PubMed - indexed for MEDLINE]
19.

Persistent transgene expression in the hypothalamus following stereotaxic delivery of a recombinant adenovirus: suppression of the immune response with cyclosporin.

Geddes BJ, Harding TC, Hughes DS, Byrnes AP, Lightman SL, Conde G, Uney JB.

Endocrinology. 1996 Nov;137(11):5166-9.

PMID:
8895393
[PubMed - indexed for MEDLINE]
20.

The emerging concept of relaxin as a centrally acting peptide hormone with hemodynamic actions.

Geddes BJ, Summerlee AJ.

J Neuroendocrinol. 1995 Jun;7(6):411-7. Review.

PMID:
7550288
[PubMed - indexed for MEDLINE]

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