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Items: 1 to 20 of 38

1.

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.

Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P, Hill DE, Vidal M, Roth FP.

Mol Syst Biol. 2016 Apr 22;12(4):863. doi: 10.15252/msb.20156660.

2.

Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.

Pandyra AA, Mullen PJ, Goard CA, Ericson E, Sharma P, Kalkat M, Yu R, Pong JT, Brown KR, Hart T, Gebbia M, Lang KS, Giaever G, Nislow C, Moffat J, Penn LZ.

Oncotarget. 2015 Sep 29;6(29):26909-21. doi: 10.18632/oncotarget.4817.

3.

Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells.

Bernard D, Gebbia M, Prabha S, Gronda M, MacLean N, Wang X, Hurren R, Sukhai MA, Cho EE, Manolson MF, Datti A, Wrana J, Minden MD, Al-Awar R, Aman A, Nislow C, Giaever G, Schimmer AD.

Apoptosis. 2015 Jul;20(7):948-59. doi: 10.1007/s10495-015-1123-3.

PMID:
25832785
4.

Genes required for survival in microgravity revealed by genome-wide yeast deletion collections cultured during spaceflight.

Nislow C, Lee AY, Allen PL, Giaever G, Smith A, Gebbia M, Stodieck LS, Hammond JS, Birdsall HH, Hammond TG.

Biomed Res Int. 2015;2015:976458. doi: 10.1155/2015/976458. Epub 2015 Jan 13.

5.

Mapping the cellular response to small molecules using chemogenomic fitness signatures.

Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, Suresh S, Duby G, Heisler LE, Surendra A, Fung E, Urbanus ML, Gebbia M, Lissina E, Miranda M, Chiang JH, Aparicio AM, Zeghouf M, Davis RW, Cherfils J, Boutry M, Kaiser CA, Cummins CL, Trimble WS, Brown GW, Schimmer AD, Bankaitis VA, Nislow C, Bader GD, Giaever G.

Science. 2014 Apr 11;344(6180):208-11. doi: 10.1126/science.1250217. Erratum in: Science. 2014 May 23;344(6186):1255771.

6.

A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription.

van Bakel H, Tsui K, Gebbia M, Mnaimneh S, Hughes TR, Nislow C.

PLoS Genet. 2013 May;9(5):e1003479. doi: 10.1371/journal.pgen.1003479. Epub 2013 May 2.

7.

Chromatin is an ancient innovation conserved between Archaea and Eukarya.

Ammar R, Torti D, Tsui K, Gebbia M, Durbic T, Bader GD, Giaever G, Nislow C.

Elife. 2012 Dec 13;1:e00078. doi: 10.7554/eLife.00078.

8.

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.

Sukhai MA, Prabha S, Hurren R, Rutledge AC, Lee AY, Sriskanthadevan S, Sun H, Wang X, Skrtic M, Seneviratne A, Cusimano M, Jhas B, Gronda M, MacLean N, Cho EE, Spagnuolo PA, Sharmeen S, Gebbia M, Urbanus M, Eppert K, Dissanayake D, Jonet A, Dassonville-Klimpt A, Li X, Datti A, Ohashi PS, Wrana J, Rogers I, Sonnet P, Ellis WY, Corey SJ, Eaves C, Minden MD, Wang JC, Dick JE, Nislow C, Giaever G, Schimmer AD.

J Clin Invest. 2013 Jan;123(1):315-28. doi: 10.1172/JCI64180. Epub 2012 Dec 3.

9.

Timing of transcriptional quiescence during gametogenesis is controlled by global histone H3K4 demethylation.

Xu M, Soloveychik M, Ranger M, Schertzberg M, Shah Z, Raisner R, Venkatasubrahmanyan S, Tsui K, Gebbia M, Hughes T, van Bakel H, Nislow C, Madhani HD, Meneghini MD.

Dev Cell. 2012 Nov 13;23(5):1059-71. doi: 10.1016/j.devcel.2012.10.005. Epub 2012 Nov 1.

10.

Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.

Tomson BN, Crisucci EM, Heisler LE, Gebbia M, Nislow C, Arndt KM.

Mol Cell Biol. 2013 Jan;33(1):170-82. doi: 10.1128/MCB.01233-12. Epub 2012 Oct 29.

11.

Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics.

Jaime MD, Lopez-Llorca LV, Conesa A, Lee AY, Proctor M, Heisler LE, Gebbia M, Giaever G, Westwood JT, Nislow C.

BMC Genomics. 2012 Jun 22;13:267. doi: 10.1186/1471-2164-13-267.

12.

A global perspective of the genetic basis for carbonyl stress resistance.

Hoon S, Gebbia M, Costanzo M, Davis RW, Giaever G, Nislow C.

G3 (Bethesda). 2011 Aug;1(3):219-31. doi: 10.1534/g3.111.000505. Epub 2011 Aug 1.

13.

Mitochondrial electron transport is the cellular target of the oncology drug elesclomol.

Blackman RK, Cheung-Ong K, Gebbia M, Proia DA, He S, Kepros J, Jonneaux A, Marchetti P, Kluza J, Rao PE, Wada Y, Giaever G, Nislow C.

PLoS One. 2012;7(1):e29798. doi: 10.1371/journal.pone.0029798. Epub 2012 Jan 11.

14.

Genomic approaches for determining nucleosome occupancy in yeast.

Tsui K, Durbic T, Gebbia M, Nislow C.

Methods Mol Biol. 2012;833:389-411. doi: 10.1007/978-1-61779-477-3_23.

PMID:
22183606
15.

Multiple means to the same end: the genetic basis of acquired stress resistance in yeast.

Berry DB, Guan Q, Hose J, Haroon S, Gebbia M, Heisler LE, Nislow C, Giaever G, Gasch AP.

PLoS Genet. 2011 Nov;7(11):e1002353. doi: 10.1371/journal.pgen.1002353. Epub 2011 Nov 10.

16.

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.

Skrtić M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai CK, Eberhard Y, Bartoszko J, Spagnuolo P, Rutledge AC, Datti A, Ketela T, Moffat J, Robinson BH, Cameron JH, Wrana J, Eaves CJ, Minden MD, Wang JC, Dick JE, Humphries K, Nislow C, Giaever G, Schimmer AD.

Cancer Cell. 2011 Nov 15;20(5):674-88. doi: 10.1016/j.ccr.2011.10.015.

17.

Nucleosome-coupled expression differences in closely-related species.

Guan Y, Yao V, Tsui K, Gebbia M, Dunham MJ, Nislow C, Troyanskaya OG.

BMC Genomics. 2011 Sep 26;12:466. doi: 10.1186/1471-2164-12-466.

18.

Evolution of nucleosome occupancy: conservation of global properties and divergence of gene-specific patterns.

Tsui K, Dubuis S, Gebbia M, Morse RH, Barkai N, Tirosh I, Nislow C.

Mol Cell Biol. 2011 Nov;31(21):4348-55. doi: 10.1128/MCB.05276-11. Epub 2011 Sep 6.

19.

Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases.

Klein M, Morillas M, Vendrell A, Brive L, Gebbia M, Wallace IM, Giaever G, Nislow C, Posas F, Grøtli M.

PLoS One. 2011;6(6):e20789. doi: 10.1371/journal.pone.0020789. Epub 2011 Jun 17.

20.

Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast.

Dinér P, Veide Vilg J, Kjellén J, Migdal I, Andersson T, Gebbia M, Giaever G, Nislow C, Hohmann S, Wysocki R, Tamás MJ, Grøtli M.

PLoS One. 2011;6(5):e20012. doi: 10.1371/journal.pone.0020012. Epub 2011 May 31.

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