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Results: 1 to 20 of 34

1.

Mapping the cellular response to small molecules using chemogenomic fitness signatures.

Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, Suresh S, Duby G, Heisler LE, Surendra A, Fung E, Urbanus ML, Gebbia M, Lissina E, Miranda M, Chiang JH, Aparicio AM, Zeghouf M, Davis RW, Cherfils J, Boutry M, Kaiser CA, Cummins CL, Trimble WS, Brown GW, Schimmer AD, Bankaitis VA, Nislow C, Bader GD, Giaever G.

Science. 2014 Apr 11;344(6180):208-11. doi: 10.1126/science.1250217. Erratum in: Science. 2014 May 23;344(6186):1255771.

PMID:
24723613
[PubMed - indexed for MEDLINE]
2.

A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription.

van Bakel H, Tsui K, Gebbia M, Mnaimneh S, Hughes TR, Nislow C.

PLoS Genet. 2013 May;9(5):e1003479. doi: 10.1371/journal.pgen.1003479. Epub 2013 May 2.

PMID:
23658529
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Chromatin is an ancient innovation conserved between Archaea and Eukarya.

Ammar R, Torti D, Tsui K, Gebbia M, Durbic T, Bader GD, Giaever G, Nislow C.

Elife (Cambridge). 2012 Dec 13;1:e00078. doi: 10.7554/eLife.00078.

PMID:
23240084
[PubMed]
Free PMC Article
4.

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.

Sukhai MA, Prabha S, Hurren R, Rutledge AC, Lee AY, Sriskanthadevan S, Sun H, Wang X, Skrtic M, Seneviratne A, Cusimano M, Jhas B, Gronda M, MacLean N, Cho EE, Spagnuolo PA, Sharmeen S, Gebbia M, Urbanus M, Eppert K, Dissanayake D, Jonet A, Dassonville-Klimpt A, Li X, Datti A, Ohashi PS, Wrana J, Rogers I, Sonnet P, Ellis WY, Corey SJ, Eaves C, Minden MD, Wang JC, Dick JE, Nislow C, Giaever G, Schimmer AD.

J Clin Invest. 2013 Jan 2;123(1):315-28. doi: 10.1172/JCI64180. Epub 2012 Dec 3.

PMID:
23202731
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Timing of transcriptional quiescence during gametogenesis is controlled by global histone H3K4 demethylation.

Xu M, Soloveychik M, Ranger M, Schertzberg M, Shah Z, Raisner R, Venkatasubrahmanyan S, Tsui K, Gebbia M, Hughes T, van Bakel H, Nislow C, Madhani HD, Meneghini MD.

Dev Cell. 2012 Nov 13;23(5):1059-71. doi: 10.1016/j.devcel.2012.10.005. Epub 2012 Nov 1.

PMID:
23123093
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.

Tomson BN, Crisucci EM, Heisler LE, Gebbia M, Nislow C, Arndt KM.

Mol Cell Biol. 2013 Jan;33(1):170-82. doi: 10.1128/MCB.01233-12. Epub 2012 Oct 29.

PMID:
23109428
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics.

Jaime MD, Lopez-Llorca LV, Conesa A, Lee AY, Proctor M, Heisler LE, Gebbia M, Giaever G, Westwood JT, Nislow C.

BMC Genomics. 2012 Jun 22;13:267. doi: 10.1186/1471-2164-13-267.

PMID:
22727066
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A global perspective of the genetic basis for carbonyl stress resistance.

Hoon S, Gebbia M, Costanzo M, Davis RW, Giaever G, Nislow C.

G3 (Bethesda). 2011 Aug;1(3):219-31. doi: 10.1534/g3.111.000505. Epub 2011 Aug 1.

PMID:
22384333
[PubMed]
Free PMC Article
9.

Mitochondrial electron transport is the cellular target of the oncology drug elesclomol.

Blackman RK, Cheung-Ong K, Gebbia M, Proia DA, He S, Kepros J, Jonneaux A, Marchetti P, Kluza J, Rao PE, Wada Y, Giaever G, Nislow C.

PLoS One. 2012;7(1):e29798. doi: 10.1371/journal.pone.0029798. Epub 2012 Jan 11.

PMID:
22253786
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Genomic approaches for determining nucleosome occupancy in yeast.

Tsui K, Durbic T, Gebbia M, Nislow C.

Methods Mol Biol. 2012;833:389-411. doi: 10.1007/978-1-61779-477-3_23.

PMID:
22183606
[PubMed - indexed for MEDLINE]
11.

Multiple means to the same end: the genetic basis of acquired stress resistance in yeast.

Berry DB, Guan Q, Hose J, Haroon S, Gebbia M, Heisler LE, Nislow C, Giaever G, Gasch AP.

PLoS Genet. 2011 Nov;7(11):e1002353. doi: 10.1371/journal.pgen.1002353. Epub 2011 Nov 10.

PMID:
22102822
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.

Skrtić M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai CK, Eberhard Y, Bartoszko J, Spagnuolo P, Rutledge AC, Datti A, Ketela T, Moffat J, Robinson BH, Cameron JH, Wrana J, Eaves CJ, Minden MD, Wang JC, Dick JE, Humphries K, Nislow C, Giaever G, Schimmer AD.

Cancer Cell. 2011 Nov 15;20(5):674-88. doi: 10.1016/j.ccr.2011.10.015.

PMID:
22094260
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Nucleosome-coupled expression differences in closely-related species.

Guan Y, Yao V, Tsui K, Gebbia M, Dunham MJ, Nislow C, Troyanskaya OG.

BMC Genomics. 2011 Sep 26;12:466. doi: 10.1186/1471-2164-12-466.

PMID:
21942931
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Evolution of nucleosome occupancy: conservation of global properties and divergence of gene-specific patterns.

Tsui K, Dubuis S, Gebbia M, Morse RH, Barkai N, Tirosh I, Nislow C.

Mol Cell Biol. 2011 Nov;31(21):4348-55. doi: 10.1128/MCB.05276-11. Epub 2011 Sep 6.

PMID:
21896781
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases.

Klein M, Morillas M, Vendrell A, Brive L, Gebbia M, Wallace IM, Giaever G, Nislow C, Posas F, Grøtli M.

PLoS One. 2011;6(6):e20789. doi: 10.1371/journal.pone.0020789. Epub 2011 Jun 17.

PMID:
21698101
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast.

Dinér P, Veide Vilg J, Kjellén J, Migdal I, Andersson T, Gebbia M, Giaever G, Nislow C, Hohmann S, Wysocki R, Tamás MJ, Grøtli M.

PLoS One. 2011;6(5):e20012. doi: 10.1371/journal.pone.0020012. Epub 2011 May 31.

PMID:
21655328
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters.

Badis G, Chan ET, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson CD, Gossett AJ, Hasinoff MJ, Warren CL, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo ZX, Clarke ND, Lieb JD, Ansari AZ, Nislow C, Hughes TR.

Mol Cell. 2008 Dec 26;32(6):878-87. doi: 10.1016/j.molcel.2008.11.020.

PMID:
19111667
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.

Ericson E, Gebbia M, Heisler LE, Wildenhain J, Tyers M, Giaever G, Nislow C.

PLoS Genet. 2008 Aug 8;4(8):e1000151. doi: 10.1371/journal.pgen.1000151.

PMID:
18688276
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.

Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, Andrews B, Boone C, Berger SL, Hieter P, Zhang Z, Brown GW, Ingles CJ, Emili A, Allis CD, Toczyski DP, Weissman JS, Greenblatt JF, Krogan NJ.

Nature. 2007 Apr 12;446(7137):806-10. Epub 2007 Feb 21.

PMID:
17314980
[PubMed - indexed for MEDLINE]
20.

PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs.

Pitre S, Dehne F, Chan A, Cheetham J, Duong A, Emili A, Gebbia M, Greenblatt J, Jessulat M, Krogan N, Luo X, Golshani A.

BMC Bioinformatics. 2006 Jul 27;7:365.

PMID:
16872538
[PubMed - indexed for MEDLINE]
Free PMC Article

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