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Results: 1 to 20 of 625

1.

Genetic mutation of p53 and suppression of the miR-17~92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D signaling.

Borkowski R, Du L, Zhao Z, McMillan E, Kosti A, Yang C, Suraokar M, Wistuba II, Gazdar AF, Minna JD, White M, Pertsemlidis A.

Cancer Res. 2014 Dec 17. pii: canres.1329.2014. [Epub ahead of print]

PMID:
25519225
[PubMed - as supplied by publisher]
2.

Proteomic signatures associated with p53 mutational status in lung adenocarcinoma.

Taguchi A, Delgado O, Celiktaş M, Katayama H, Wang H, Gazdar AF, Hanash SM.

Proteomics. 2014 Dec;14(23-24):2750-9. doi: 10.1002/pmic.201400378. Epub 2014 Nov 20.

PMID:
25331784
[PubMed - in process]
3.

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers.

Augustyn A, Borromeo M, Wang T, Fujimoto J, Shao C, Dospoy PD, Lee V, Tan C, Sullivan JP, Larsen JE, Girard L, Behrens C, Wistuba II, Xie Y, Cobb MH, Gazdar AF, Johnson JE, Minna JD.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14788-93. doi: 10.1073/pnas.1410419111. Epub 2014 Sep 29.

PMID:
25267614
[PubMed - in process]
Free PMC Article
4.

A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets.

Taguchi A, Taylor AD, Rodriguez J, Celiktaş M, Liu H, Ma X, Zhang Q, Wong CH, Chin A, Girard L, Behrens C, Lam WL, Lam S, Minna JD, Wistuba II, Gazdar AF, Hanash SM.

Cancer Res. 2014 Sep 1;74(17):4694-705. doi: 10.1158/0008-5472.CAN-13-3725. Epub 2014 Jun 26.

PMID:
24970476
[PubMed - in process]
5.

Analysis of TP53 mutation status in human cancer cell lines: a reassessment.

Leroy B, Girard L, Hollestelle A, Minna JD, Gazdar AF, Soussi T.

Hum Mutat. 2014 Jun;35(6):756-65. doi: 10.1002/humu.22556. Epub 2014 May 6. Review.

PMID:
24700732
[PubMed - indexed for MEDLINE]
6.

Methylation analysis in spontaneous sputum for lung cancer diagnosis.

Hubers AJ, van der Drift MA, Prinsen CF, Witte BI, Wang Y, Shivapurkar N, Stastny V, Bolijn AS, Hol BE, Feng Z, Dekhuijzen PN, Gazdar AF, Thunnissen E.

Lung Cancer. 2014 May;84(2):127-33. doi: 10.1016/j.lungcan.2014.01.019. Epub 2014 Jan 31.

PMID:
24598366
[PubMed - indexed for MEDLINE]
7.

Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer.

Delgado O, Batten KG, Richardson JA, Xie XJ, Gazdar AF, Kaisani AA, Girard L, Behrens C, Suraokar M, Fasciani G, Wright WE, Story MD, Wistuba II, Minna JD, Shay JW.

Clin Cancer Res. 2014 Mar 15;20(6):1610-22. doi: 10.1158/1078-0432.CCR-13-2589. Epub 2014 Jan 31.

PMID:
24486591
[PubMed - indexed for MEDLINE]
8.

EGFR mutations in lung cancer: different frequencies for different folks.

Gazdar AF.

J Thorac Oncol. 2014 Feb;9(2):139-40. doi: 10.1097/JTO.0000000000000063. No abstract available.

PMID:
24419408
[PubMed - indexed for MEDLINE]
9.

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.

Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA.

Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24.

PMID:
24243015
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

YEATS4 is a novel oncogene amplified in non-small cell lung cancer that regulates the p53 pathway.

Pikor LA, Lockwood WW, Thu KL, Vucic EA, Chari R, Gazdar AF, Lam S, Lam WL.

Cancer Res. 2013 Dec 15;73(24):7301-12. doi: 10.1158/0008-5472.CAN-13-1897. Epub 2013 Oct 29.

PMID:
24170126
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The pivotal role of pathology in the management of lung cancer.

Davidson MR, Gazdar AF, Clarke BE.

J Thorac Dis. 2013 Oct;5 Suppl 5:S463-78. doi: 10.3978/j.issn.2072-1439.2013.08.43. Review.

PMID:
24163740
[PubMed]
Free PMC Article
12.

EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk.

Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, MacAulay CE, Karsan A, Gazdar AF, Lam S, Lam WL.

Oncogene. 2014 Sep 4;33(36):4464-73. doi: 10.1038/onc.2013.396. Epub 2013 Oct 7.

PMID:
24096489
[PubMed - indexed for MEDLINE]
13.

Genomic deregulation of the E2F/Rb pathway leads to activation of the oncogene EZH2 in small cell lung cancer.

Coe BP, Thu KL, Aviel-Ronen S, Vucic EA, Gazdar AF, Lam S, Tsao MS, Lam WL.

PLoS One. 2013 Aug 15;8(8):e71670. doi: 10.1371/journal.pone.0071670. eCollection 2013.

PMID:
23967231
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Precision medicine for cancer patients: lessons learned and the path forward.

Gazdar AF, Minna JD.

J Natl Cancer Inst. 2013 Sep 4;105(17):1262-3. doi: 10.1093/jnci/djt219. Epub 2013 Aug 20. No abstract available.

PMID:
23964132
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Progenitor cell line (hPheo1) derived from a human pheochromocytoma tumor.

Ghayee HK, Bhagwandin VJ, Stastny V, Click A, Ding LH, Mizrachi D, Zou YS, Chari R, Lam WL, Bachoo RM, Smith AL, Story MD, Sidhu S, Robinson BG, Nwariaku FE, Gazdar AF, Auchus RJ, Shay JW.

PLoS One. 2013 Jun 13;8(6):e65624. doi: 10.1371/journal.pone.0065624. Print 2013.

PMID:
23785438
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

DNA methylation data analysis and its application to cancer research.

Ma X, Wang YW, Zhang MQ, Gazdar AF.

Epigenomics. 2013 Jun;5(3):301-16. doi: 10.2217/epi.13.26. Review.

PMID:
23750645
[PubMed - indexed for MEDLINE]
17.

Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells.

Shien K, Toyooka S, Yamamoto H, Soh J, Jida M, Thu KL, Hashida S, Maki Y, Ichihara E, Asano H, Tsukuda K, Takigawa N, Kiura K, Gazdar AF, Lam WL, Miyoshi S.

Cancer Res. 2013 May 15;73(10):3051-61. doi: 10.1158/0008-5472.CAN-12-4136. Epub 2013 Mar 29.

PMID:
23542356
[PubMed - indexed for MEDLINE]
Free Article
18.

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.

Sato M, Larsen JE, Lee W, Sun H, Shames DS, Dalvi MP, Ramirez RD, Tang H, DiMaio JM, Gao B, Xie Y, Wistuba II, Gazdar AF, Shay JW, Minna JD.

Mol Cancer Res. 2013 Jun;11(6):638-50. doi: 10.1158/1541-7786.MCR-12-0634-T. Epub 2013 Feb 28.

PMID:
23449933
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Retraction: DNA methylation profiles of lymphoid and hematopoietic malignancies.

Takahashi T, Shivapurkar N, Reddy J, Shigematsu H, Miyajima K, Suzuki M, Toyooka S, Zöchbauer-Müller S, Drach J, Parikh G, Zheng Y, Feng Z, Kroft SH, Timmons C, McKenna RW, Gazdar AF.

Clin Cancer Res. 2013 Jan 1;19(1):307. doi: 10.1158/1078-0432.CCR-12-3679. Epub 2012 Dec 17. No abstract available.

PMID:
23248096
[PubMed - indexed for MEDLINE]
Free Article
20.

Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.

Liu J, Lee W, Jiang Z, Chen Z, Jhunjhunwala S, Haverty PM, Gnad F, Guan Y, Gilbert HN, Stinson J, Klijn C, Guillory J, Bhatt D, Vartanian S, Walter K, Chan J, Holcomb T, Dijkgraaf P, Johnson S, Koeman J, Minna JD, Gazdar AF, Stern HM, Hoeflich KP, Wu TD, Settleman J, de Sauvage FJ, Gentleman RC, Neve RM, Stokoe D, Modrusan Z, Seshagiri S, Shames DS, Zhang Z.

Genome Res. 2012 Dec;22(12):2315-27. doi: 10.1101/gr.140988.112. Epub 2012 Oct 2.

PMID:
23033341
[PubMed - indexed for MEDLINE]
Free PMC Article

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