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Items: 1 to 20 of 119

1.

A multiplexed targeted assay for high-throughput quantitative analysis of serum methylamines by ultra performance liquid chromatography coupled to high resolution mass spectrometry.

Kadar H, Dubus J, Dutot J, Hedjazi L, Srinivasa S, Fitch KV, Grinspoon SK, Nicholson JK, Dumas ME, Gauguier D.

Arch Biochem Biophys. 2016 May 1;597:12-20. doi: 10.1016/j.abb.2016.03.029. Epub 2016 Mar 30.

PMID:
27036856
2.

Association of coronary artery disease and chronic kidney disease in Lebanese population.

Milane A, Khazen G, Zeineddine N, Amro M, Masri L, Ghassibe-Sabbagh M, Youhanna S, Salloum AK, Haber M, Platt DE, Cazier JB, Othman R, Kabbani S, Sbeite H, Chami Y, Chammas E, El Bayeh H, Gauguier D, Abchee AB, Zalloua P, Barbari A.

Int J Clin Exp Med. 2015 Sep 15;8(9):15866-77. eCollection 2015.

3.

Caffeine Impact on Metabolic Syndrome Components Is Modulated by a CYP1A2 Variant.

Platt DE, Ghassibe-Sabbagh M, Salameh P, Salloum AK, Haber M, Mouzaya F, Gauguier D, Al-Sarraj Y, El-Shanti H, Zalloua PA, Abchee AB.

Ann Nutr Metab. 2016;68(1):1-11. doi: 10.1159/000441481. Epub 2015 Nov 21.

PMID:
26588584
4.

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.

Ménoret S, De Cian A, Tesson L, Remy S, Usal C, Boulé JB, Boix C, Fontanière S, Crénéguy A, Nguyen TH, Brusselle L, Thinard R, Gauguier D, Concordet JP, Cherifi Y, Fraichard A, Giovannangeli C, Anegon I.

Sci Rep. 2015 Oct 7;5:14410. doi: 10.1038/srep14410.

5.

Application of quantitative metabolomics in systems genetics in rodent models of complex phenotypes.

Gauguier D.

Arch Biochem Biophys. 2016 Jan 1;589:158-67. doi: 10.1016/j.abb.2015.09.016. Epub 2015 Sep 25. Review.

PMID:
26391925
6.

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, Nielson CM, Walter K, Pettersson-Kymmer U, McCarthy S, Eriksson J, Kwan T, Jhamai M, Trajanoska K, Memari Y, Min J, Huang J, Danecek P, Wilmot B, Li R, Chou WC, Mokry LE, Moayyeri A, Claussnitzer M, Cheng CH, Cheung W, Medina-Gómez C, Ge B, Chen SH, Choi K, Oei L, Fraser J, Kraaij R, Hibbs MA, Gregson CL, Paquette D, Hofman A, Wibom C, Tranah GJ, Marshall M, Gardiner BB, Cremin K, Auer P, Hsu L, Ring S, Tung JY, Thorleifsson G, Enneman AW, van Schoor NM, de Groot LC, van der Velde N, Melin B, Kemp JP, Christiansen C, Sayers A, Zhou Y, Calderari S, van Rooij J, Carlson C, Peters U, Berlivet S, Dostie J, Uitterlinden AG, Williams SR, Farber C, Grinberg D, LaCroix AZ, Haessler J, Chasman DI, Giulianini F, Rose LM, Ridker PM, Eisman JA, Nguyen TV, Center JR, Nogues X, Garcia-Giralt N, Launer LL, Gudnason V, Mellström D, Vandenput L, Amin N, van Duijn CM, Karlsson MK, Ljunggren Ö, Svensson O, Hallmans G, Rousseau F, Giroux S, Bussière J, Arp PP, Koromani F, Prince RL, Lewis JR, Langdahl BL, Hermann AP, Jensen JE, Kaptoge S, Khaw KT, Reeve J, Formosa MM, Xuereb-Anastasi A, Åkesson K, McGuigan FE, Garg G, Olmos JM, Zarrabeitia MT, Riancho JA, Ralston SH, Alonso N, Jiang X, Goltzman D, Pastinen T, Grundberg E, Gauguier D, Orwoll ES, Karasik D, Davey-Smith G; AOGC Consortium, Smith AV, Siggeirsdottir K, Harris TB, Zillikens MC, van Meurs JB, Thorsteinsdottir U, Maurano MT, Timpson NJ, Soranzo N, Durbin R, Wilson SG, Ntzani EE, Brown MA, Stefansson K, Hinds DA, Spector T, Cupples LA, Ohlsson C, Greenwood CM; UK10K Consortium, Jackson RD, Rowe DW, Loomis CA, Evans DM, Ackert-Bicknell CL, Joyner AL, Duncan EL, Kiel DP, Rivadeneira F, Richards JB.

Nature. 2015 Oct 1;526(7571):112-7. doi: 10.1038/nature14878. Epub 2015 Sep 14.

7.

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.

Nikpay M, Goel A, Won HH, Hall LM, Willenborg C, Kanoni S, Saleheen D, Kyriakou T, Nelson CP, Hopewell JC, Webb TR, Zeng L, Dehghan A, Alver M, Armasu SM, Auro K, Bjonnes A, Chasman DI, Chen S, Ford I, Franceschini N, Gieger C, Grace C, Gustafsson S, Huang J, Hwang SJ, Kim YK, Kleber ME, Lau KW, Lu X, Lu Y, Lyytikäinen LP, Mihailov E, Morrison AC, Pervjakova N, Qu L, Rose LM, Salfati E, Saxena R, Scholz M, Smith AV, Tikkanen E, Uitterlinden A, Yang X, Zhang W, Zhao W, de Andrade M, de Vries PS, van Zuydam NR, Anand SS, Bertram L, Beutner F, Dedoussis G, Frossard P, Gauguier D, Goodall AH, Gottesman O, Haber M, Han BG, Huang J, Jalilzadeh S, Kessler T, König IR, Lannfelt L, Lieb W, Lind L, Lindgren CM, Lokki ML, Magnusson PK, Mallick NH, Mehra N, Meitinger T, Memon FU, Morris AP, Nieminen MS, Pedersen NL, Peters A, Rallidis LS, Rasheed A, Samuel M, Shah SH, Sinisalo J, Stirrups KE, Trompet S, Wang L, Zaman KS, Ardissino D, Boerwinkle E, Borecki IB, Bottinger EP, Buring JE, Chambers JC, Collins R, Cupples LA, Danesh J, Demuth I, Elosua R, Epstein SE, Esko T, Feitosa MF, Franco OH, Franzosi MG, Granger CB, Gu D, Gudnason V, Hall AS, Hamsten A, Harris TB, Hazen SL, Hengstenberg C, Hofman A, Ingelsson E, Iribarren C, Jukema JW, Karhunen PJ, Kim BJ, Kooner JS, Kullo IJ, Lehtimäki T, Loos RJ, Melander O, Metspalu A, März W, Palmer CN, Perola M, Quertermous T, Rader DJ, Ridker PM, Ripatti S, Roberts R, Salomaa V, Sanghera DK, Schwartz SM, Seedorf U, Stewart AF, Stott DJ, Thiery J, Zalloua PA, O'Donnell CJ, Reilly MP, Assimes TL, Thompson JR, Erdmann J, Clarke R, Watkins H, Kathiresan S, McPherson R, Deloukas P, Schunkert H, Samani NJ, Farrall M; CARDIoGRAMplusC4D Consortium.

Nat Genet. 2015 Oct;47(10):1121-30. doi: 10.1038/ng.3396. Epub 2015 Sep 7.

8.

ANKS3 Co-Localises with ANKS6 in Mouse Renal Cilia and Is Associated with Vasopressin Signaling and Apoptosis In Vivo in Mice.

Delestré L, Bakey Z, Prado C, Hoffmann S, Bihoreau MT, Lelongt B, Gauguier D.

PLoS One. 2015 Sep 1;10(9):e0136781. doi: 10.1371/journal.pone.0136781. eCollection 2015.

9.

The SAM domain of ANKS6 has different interacting partners and mutations can induce different cystic phenotypes.

Bakey Z, Bihoreau MT, Piedagnel R, Delestré L, Arnould C, de Villiers Ad, Devuyst O, Hoffmann S, Ronco P, Gauguier D, Lelongt B.

Kidney Int. 2015 Aug;88(2):299-310. doi: 10.1038/ki.2015.122. Epub 2015 Jun 3.

PMID:
26039630
10.

The cardiovascular effects of salidroside in the Goto-Kakizaki diabetic rat model.

Alameddine A, Fajloun Z, Bourreau J, Gauquelin-Koch G, Yuan M, Gauguier D, Derbre S, Ayer A, Custaud MA, Navasiolava N.

J Physiol Pharmacol. 2015 Apr;66(2):249-57.

11.

mQTL.NMR: an integrated suite for genetic mapping of quantitative variations of (1)H NMR-based metabolic profiles.

Hedjazi L, Gauguier D, Zalloua PA, Nicholson JK, Dumas ME, Cazier JB.

Anal Chem. 2015 Apr 21;87(8):4377-84. doi: 10.1021/acs.analchem.5b00145. Epub 2015 Apr 2.

PMID:
25803548
12.

Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine.

Srinivasa S, Fitch KV, Lo J, Kadar H, Knight R, Wong K, Abbara S, Gauguier D, Capeau J, Boccara F, Grinspoon SK.

AIDS. 2015 Feb 20;29(4):443-52. doi: 10.1097/QAD.0000000000000565.

13.

T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility.

Ghassibe-Sabbagh M, Haber M, Salloum AK, Al-Sarraj Y, Akle Y, Hirbli K, Romanos J, Mouzaya F, Gauguier D, Platt DE, El-Shanti H, Zalloua PA.

Sci Rep. 2014 Dec 8;4:7351. doi: 10.1038/srep07351.

14.

Association of hypertension with coronary artery disease onset in the Lebanese population.

Milane A, Abdallah J, Kanbar R, Khazen G, Ghassibe-Sabbagh M, Salloum AK, Youhanna S, Saad A, El Bayeh H, Chammas E, Platt DE, Hager J, Gauguier D, Zalloua P, Abchee A; FGENTCARD Consortium.

Springerplus. 2014 Sep 16;3:533. doi: 10.1186/2193-1801-3-533. eCollection 2014.

15.

Protease inhibitor 15, a candidate gene for abdominal aortic internal elastic lamina ruptures in the rat.

Falak S, Schafer S, Baud A, Hummel O, Schulz H, Gauguier D, Hubner N, Osborne-Pellegrin M.

Physiol Genomics. 2014 Jun 15;46(12):418-28. doi: 10.1152/physiolgenomics.00004.2014. Epub 2014 May 1.

16.

Circulating lipid levels and risk of coronary artery disease in a large group of patients undergoing coronary angiography.

Platt DE, Ghassibe-Sabbagh M, Youhanna S, Hager J, Cazier JB, Kamatani Y, Salloum AK, Haber M, Romanos J, Doueihy B, Mouzaya F, Kibbani S, Sbeite H, Deeb ME, Chammas E, El Bayeh H, Khazen G, Gauguier D, Zalloua PA, Abchee AB; FGENTCARD Consortium.

J Thromb Thrombolysis. 2015 Jan;39(1):15-22. doi: 10.1007/s11239-014-1069-2.

PMID:
24788070
17.

Genetic control of differential acetylation in diabetic rats.

Kaisaki PJ, Otto GW, McGouran JF, Toubal A, Argoud K, Waller-Evans H, Finlay C, Caldérari S, Bihoreau MT, Kessler BM, Gauguier D, Mott R.

PLoS One. 2014 Apr 17;9(4):e94555. doi: 10.1371/journal.pone.0094555. eCollection 2014.

18.

Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men.

Diawara MR, Hue C, Wilder SP, Venteclef N, Aron-Wisnewsky J, Scott J, Clément K, Gauguier D, Calderari S.

PLoS One. 2014 Mar 27;9(3):e91375. doi: 10.1371/journal.pone.0091375. eCollection 2014.

19.

Regenerating 1 and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats.

Calderari S, Irminger JC, Giroix MH, Ehses JA, Gangnerau MN, Coulaud J, Rickenbach K, Gauguier D, Halban P, Serradas P, Homo-Delarche F.

PLoS One. 2014 Feb 26;9(2):e90045. doi: 10.1371/journal.pone.0090045. eCollection 2014.

20.

Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome.

Waller-Evans H, Hue C, Fearnside J, Rothwell AR, Lockstone HE, Caldérari S, Wilder SP, Cazier JB, Scott J, Gauguier D.

PLoS One. 2013 Dec 6;8(12):e82825. doi: 10.1371/journal.pone.0082825. eCollection 2013.

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