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Results: 1 to 20 of 193

1.

Genetics and Causality of Triglyceride-Rich Lipoproteins in Atherosclerotic Cardiovascular Disease.

Rosenson RS, Davidson MH, Hirsh BJ, Kathiresan S, Gaudet D.

J Am Coll Cardiol. 2014 Dec 16;64(23):2525-2540. doi: 10.1016/j.jacc.2014.09.042. Review.

PMID:
25500239
[PubMed - as supplied by publisher]
2.

Targeting APOC3 in the familial chylomicronemia syndrome.

Gaudet D, Brisson D, Tremblay K, Alexander VJ, Singleton W, Hughes SG, Geary RS, Baker BF, Graham MJ, Crooke RM, Witztum JL.

N Engl J Med. 2014 Dec 4;371(23):2200-6. doi: 10.1056/NEJMoa1400284.

PMID:
25470695
[PubMed - indexed for MEDLINE]
3.

Saguenay Youth Study: A multi-generational approach to studying virtual trajectories of the brain and cardio-metabolic health.

Paus T, Pausova Z, Abrahamowicz M, Gaudet D, Leonard G, Pike GB, Richer L.

Dev Cogn Neurosci. 2014 Oct 23. pii: S1878-9293(14)00071-1. doi: 10.1016/j.dcn.2014.10.003. [Epub ahead of print]

PMID:
25454417
[PubMed - as supplied by publisher]
Free Article
4.

Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia.

Primary Panel:, Genest J, Hegele RA, Bergeron J, Brophy J, Carpentier A, Couture P, Davignon J, Dufour R, Frohlich J, Gaudet D, Gupta M, Krisnamoorthy P, Mancini J, McCrindle B, Raggi P, Ruel I, St-Pierre J.

Can J Cardiol. 2014 Dec;30(12):1471-81. doi: 10.1016/j.cjca.2014.09.028. Epub 2014 Oct 2.

PMID:
25448461
[PubMed - in process]
Free Article
5.

The Stripe Rust Resistance Gene Yr10 Encodes an Evolutionary-Conserved and Unique CC-NBS-LRR Sequence in Wheat.

Liu W, Frick M, Huel R, Nykiforuk CL, Wang X, Gaudet DA, Eudes F, Conner RL, Kuzyk A, Chen Q, Kang Z, Laroche A.

Mol Plant. 2014 Dec;7(12):1740-55. doi: 10.1093/mp/ssu112. Epub 2014 Oct 20.

PMID:
25336565
[PubMed - in process]
6.

Prenatal Exposure to Maternal Cigarette Smoking and DNA Methylation: Epigenome-Wide Association in a Discovery Sample of Adolescents and Replication in an Independent Cohort at Birth through 17 Years of Age.

Lee KW, Richmond R, Hu P, French L, Shin J, Bourdon C, Reischl E, Waldenberger M, Zeilinger S, Gaunt T, McArdle W, Ring S, Woodward G, Bouchard L, Gaudet D, Davey-Smith G, Relton C, Paus T, Pausova Z.

Environ Health Perspect. 2014 Oct 17. [Epub ahead of print]

PMID:
25325234
[PubMed - as supplied by publisher]
Free Article
7.

PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial.

Raal FJ, Stein EA, Dufour R, Turner T, Civeira F, Burgess L, Langslet G, Scott R, Olsson AG, Sullivan D, Hovingh GK, Cariou B, Gouni-Berthold I, Somaratne R, Bridges I, Scott R, Wasserman SM, Gaudet D; for the RUTHERFORD-2 Investigators.

Lancet. 2014 Oct 1. pii: S0140-6736(14)61399-4. doi: 10.1016/S0140-6736(14)61399-4. [Epub ahead of print]

PMID:
25282519
[PubMed - as supplied by publisher]
8.

Prenatal exposure to cigarette smoke interacts with OPRM1 to modulate dietary preference for fat.

Lee KW, Abrahamowicz M, Leonard GT, Richer L, Perron M, Veillette S, Reischl E, Bouchard L, Gaudet D, Paus T, Pausova Z.

J Psychiatry Neurosci. 2015 Jan;40(1):38-45.

PMID:
25266401
[PubMed - in process]
Free PMC Article
9.

The potential applications of Apolipoprotein E in personalized medicine.

Villeneuve S, Brisson D, Marchant NL, Gaudet D.

Front Aging Neurosci. 2014 Jul 8;6:154. doi: 10.3389/fnagi.2014.00154. eCollection 2014. Review.

PMID:
25071563
[PubMed]
Free PMC Article
10.

Effect of alirocumab, a monoclonal proprotein convertase subtilisin/kexin 9 antibody, on lipoprotein(a) concentrations (a pooled analysis of 150 mg every two weeks dosing from phase 2 trials).

Gaudet D, Kereiakes DJ, McKenney JM, Roth EM, Hanotin C, Gipe D, Du Y, Ferrand AC, Ginsberg HN, Stein EA.

Am J Cardiol. 2014 Sep 1;114(5):711-5. doi: 10.1016/j.amjcard.2014.05.060. Epub 2014 Jun 18.

PMID:
25060413
[PubMed - indexed for MEDLINE]
Free Article
11.

An immunity-triggering effector from the Barley smut fungus Ustilago hordei resides in an Ustilaginaceae-specific cluster bearing signs of transposable element-assisted evolution.

Ali S, Laurie JD, Linning R, Cervantes-Chávez JA, Gaudet D, Bakkeren G.

PLoS Pathog. 2014 Jul 3;10(7):e1004223. doi: 10.1371/journal.ppat.1004223. eCollection 2014 Jul.

PMID:
24992661
[PubMed - in process]
Free PMC Article
12.

Reply to: NGS library preparation may generate artifactual integration sites of AAV vectors.

Kaeppel C, Beattie SG, Fronza R, van Logtenstein R, Salmon F, Schmidt S, Wolf S, Nowrouzi A, Glimm H, von Kalle C, Petry H, Gaudet D, Schmidt M.

Nat Med. 2014 Jun;20(6):578-9. doi: 10.1038/nm.3584. No abstract available.

PMID:
24901561
[PubMed - indexed for MEDLINE]
13.

Placental lipoprotein lipase DNA methylation levels are associated with gestational diabetes mellitus and maternal and cord blood lipid profiles.

Houde AA, St-Pierre J, Hivert MF, Baillargeon JP, Perron P, Gaudet D, Brisson D, Bouchard L.

J Dev Orig Health Dis. 2014 Apr;5(2):132-41. doi: 10.1017/S2040174414000038.

PMID:
24847699
[PubMed - indexed for MEDLINE]
14.

Epigenetic dysregulation of the IGF system in placenta of newborns exposed to maternal impaired glucose tolerance.

Desgagné V, Hivert MF, St-Pierre J, Guay SP, Baillargeon JP, Perron P, Gaudet D, Brisson D, Bouchard L.

Epigenomics. 2014 Apr;6(2):193-207. doi: 10.2217/epi.14.3.

PMID:
24811788
[PubMed - indexed for MEDLINE]
15.

Association of CTRC and SPINK1 gene variants with recurrent hospitalizations for pancreatitis or acute abdominal pain in lipoprotein lipase deficiency.

Tremblay K, Dubois-Bouchard C, Brisson D, Gaudet D.

Front Genet. 2014 Apr 22;5:90. doi: 10.3389/fgene.2014.00090. eCollection 2014.

PMID:
24795752
[PubMed]
Free PMC Article
16.

ADRB3 gene promoter DNA methylation in blood and visceral adipose tissue is associated with metabolic disturbances in men.

Guay SP, Brisson D, Lamarche B, Biron S, Lescelleur O, Biertho L, Marceau S, Vohl MC, Gaudet D, Bouchard L.

Epigenomics. 2014 Feb;6(1):33-43. doi: 10.2217/epi.13.82.

PMID:
24579945
[PubMed - indexed for MEDLINE]
17.

Epipolymorphisms within lipoprotein genes contribute independently to plasma lipid levels in familial hypercholesterolemia.

Guay SP, Brisson D, Lamarche B, Gaudet D, Bouchard L.

Epigenetics. 2014 May;9(5):718-29. doi: 10.4161/epi.27981. Epub 2014 Feb 6.

PMID:
24504152
[PubMed - indexed for MEDLINE]
18.

Clustering of the metabolic syndrome components in adolescence: role of visceral fat.

Melka MG, Abrahamowicz M, Leonard GT, Perron M, Richer L, Veillette S, Gaudet D, Paus T, Pausova Z.

PLoS One. 2013 Dec 20;8(12):e82368. doi: 10.1371/journal.pone.0082368. eCollection 2013.

PMID:
24376531
[PubMed - in process]
Free PMC Article
19.

Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy.

Ferreira V, Twisk J, Kwikkers K, Aronica E, Brisson D, Methot J, Petry H, Gaudet D.

Hum Gene Ther. 2014 Mar;25(3):180-8. doi: 10.1089/hum.2013.169. Epub 2014 Feb 28.

PMID:
24299335
[PubMed - indexed for MEDLINE]
20.

Genealogical analysis as a new approach for the investigation of drug intolerance heritability.

Tremblay M, Bouhali T, Gaudet D, Brisson D.

Eur J Hum Genet. 2014 Jul;22(7):916-22. doi: 10.1038/ejhg.2013.270. Epub 2013 Nov 27.

PMID:
24281370
[PubMed - in process]

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