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Results: 1 to 20 of 280

1.

Repetitive concussions - How dangerous are they?

Zetterberg H, Gandy S.

Mol Cell Neurosci. 2015 Feb 3. pii: S1044-7431(15)00015-9. doi: 10.1016/j.mcn.2015.02.004. [Epub ahead of print] No abstract available.

PMID:
25655012
[PubMed - as supplied by publisher]
2.

[18F]-T807 tauopathy PET imaging in chronic traumatic encephalopathy.

Gandy S, DeKosky ST.

F1000Res. 2014 Sep 29;3:229. doi: 10.12688/f1000research.5372.1. eCollection 2014.

PMID:
25469232
[PubMed]
Free PMC Article
3.

An increased B-type natriuretic peptide in the absence of a cardiac abnormality identifies those whose left ventricular mass will increase over time.

Nadir MA, Gandy S, Ireland S, MacDonald T, Dow E, Houston G, Lang C, Struthers A.

JACC Heart Fail. 2015 Jan;3(1):87-93. doi: 10.1016/j.jchf.2014.07.012. Epub 2014 Nov 11.

PMID:
25454393
[PubMed - in process]
Free Article
4.

Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aβ.

Knight EM, Williams HN, Stevens AC, Kim SH, Kottwitz JC, Morant AD, Steele JW, Klein WL, Yanagisawa K, Boyd RE, Lockhart DJ, Sjoberg ER, Ehrlich ME, Wustman BA, Gandy S.

Mol Psychiatry. 2015 Feb;20(1):109-17. doi: 10.1038/mp.2014.135. Epub 2014 Oct 28.

PMID:
25349165
[PubMed - in process]
5.

Chronic traumatic encephalopathy: clinical-biomarker correlations and current concepts in pathogenesis.

Gandy S, Ikonomovic MD, Mitsis E, Elder G, Ahlers ST, Barth J, Stone JR, DeKosky ST.

Mol Neurodegener. 2014 Sep 17;9:37. doi: 10.1186/1750-1326-9-37.

PMID:
25231386
[PubMed - in process]
Free PMC Article
6.

Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions.

Ortiz-Virumbrales M, Ruiz M, Hone E, Dolios G, Wang R, Morant A, Kottwitz J, Ozelius LJ, Gandy S, Ehrlich ME.

Acta Neuropathol Commun. 2014 Sep 18;2(1):139. doi: 10.1186/s40478-014-0139-1.

PMID:
25231164
[PubMed - in process]
Free PMC Article
7.

Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury.

Mitsis EM, Riggio S, Kostakoglu L, Dickstein DL, Machac J, Delman B, Goldstein M, Jennings D, D'Antonio E, Martin J, Naidich TP, Aloysi A, Fernandez C, Seibyl J, DeKosky ST, Elder GA, Marek K, Gordon W, Hof PR, Sano M, Gandy S.

Transl Psychiatry. 2014 Sep 16;4:e441. doi: 10.1038/tp.2014.91.

PMID:
25226550
[PubMed - in process]
Free PMC Article
8.

Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse.

Kim SH, Steele JW, Lee SW, Clemenson GD, Carter TA, Treuner K, Gadient R, Wedel P, Glabe C, Barlow C, Ehrlich ME, Gage FH, Gandy S.

Mol Psychiatry. 2014 Nov;19(11):1235-42. doi: 10.1038/mp.2014.87. Epub 2014 Aug 12.

PMID:
25113378
[PubMed - in process]
Free PMC Article
9.

Pentameric thiophene-based ligands that spectrally discriminate amyloid-β and tau aggregates display distinct solvatochromism and viscosity-induced spectral shifts.

Simon RA, Shirani H, Aslund KO, Bäck M, Haroutunian V, Gandy S, Nilsson KP.

Chemistry. 2014 Sep 22;20(39):12537-43. doi: 10.1002/chem.201402890. Epub 2014 Aug 8.

PMID:
25111601
[PubMed - in process]
10.

Alzheimer disease risk factors--reply.

DeKosky ST, Gandy S.

JAMA Neurol. 2014 Aug;71(8):1051-2. doi: 10.1001/jamaneurol.2014.636. No abstract available.

PMID:
25111207
[PubMed - indexed for MEDLINE]
11.

Common carotid intima media thickness and ankle-brachial pressure index correlate with local but not global atheroma burden: a cross sectional study using whole body magnetic resonance angiography.

Weir-McCall JR, Khan F, Lambert MA, Adamson CL, Gardner M, Gandy SJ, Ramkumar PG, Belch JJ, Struthers AD, Rauchhaus P, Morris AD, Houston JG.

PLoS One. 2014 Jun 16;9(6):e99190. doi: 10.1371/journal.pone.0099190. eCollection 2014.

PMID:
24933122
[PubMed - in process]
Free PMC Article
12.

Immunomodulation and AD--down but not out.

Knight EM, Gandy S.

J Clin Immunol. 2014 Jul;34 Suppl 1:S70-3. doi: 10.1007/s10875-014-0039-y. Epub 2014 Apr 30.

PMID:
24781637
[PubMed - in process]
13.

Alzheimer's disease research and development: a call for a new research roadmap.

Feldman HH, Haas M, Gandy S, Schoepp DD, Cross AJ, Mayeux R, Sperling RA, Fillit H, van de Hoef DL, Dougal S, Nye JS; One Mind for Research and the New York Academy of Sciences.

Ann N Y Acad Sci. 2014 Apr;1313:1-16. doi: 10.1111/nyas.12424.

PMID:
24754377
[PubMed - indexed for MEDLINE]
14.

A consecutive case series experience with [18 F] florbetapir PET imaging in an urban dementia center: impact on quality of life, decision making, and disposition.

Mitsis EM, Bender HA, Kostakoglu L, Machac J, Martin J, Woehr JL, Sewell MC, Aloysi A, Goldstein MA, Li C, Sano M, Gandy S.

Mol Neurodegener. 2014 Feb 3;9:10. doi: 10.1186/1750-1326-9-10.

PMID:
24484858
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Environmental exposures and the risk for Alzheimer disease: can we identify the smoking guns?

Dekosky ST, Gandy S.

JAMA Neurol. 2014 Mar;71(3):273-5. doi: 10.1001/jamaneurol.2013.6031. No abstract available.

PMID:
24473699
[PubMed - indexed for MEDLINE]
16.

Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial.

Witham MD, Ireland S, Houston JG, Gandy SJ, Waugh S, Macdonald TM, Mackenzie IS, Struthers AD.

Hypertension. 2014 Apr;63(4):706-12. doi: 10.1161/HYPERTENSIONAHA.113.02177. Epub 2014 Jan 13.

PMID:
24420547
[PubMed - indexed for MEDLINE]
17.

Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors.

Sproul AA, Jacob S, Pre D, Kim SH, Nestor MW, Navarro-Sobrino M, Santa-Maria I, Zimmer M, Aubry S, Steele JW, Kahler DJ, Dranovsky A, Arancio O, Crary JF, Gandy S, Noggle SA.

PLoS One. 2014 Jan 8;9(1):e84547. doi: 10.1371/journal.pone.0084547. eCollection 2014.

PMID:
24416243
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model.

Steele JW, Brautigam H, Short JA, Sowa A, Shi M, Yadav A, Weaver CM, Westaway D, Fraser PE, St George-Hyslop PH, Gandy S, Hof PR, Dickstein DL.

J Comp Neurol. 2014 Jul 1;522(10):2319-35. doi: 10.1002/cne.23536.

PMID:
24415002
[PubMed - indexed for MEDLINE]
19.

Alzheimer's disease: new data highlight nonneuronal cell types and the necessity for presymptomatic prevention strategies.

Gandy S.

Biol Psychiatry. 2014 Apr 1;75(7):553-7. doi: 10.1016/j.biopsych.2013.11.019. Epub 2013 Nov 28. Review.

PMID:
24373429
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases.

Bharadwaj PR, Bates KA, Porter T, Teimouri E, Perry G, Steele JW, Gandy S, Groth D, Martins RN, Verdile G.

Transl Psychiatry. 2013 Dec 3;3:e332. doi: 10.1038/tp.2013.97. Review.

PMID:
24301650
[PubMed - indexed for MEDLINE]
Free PMC Article
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