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Results: 1 to 20 of 276

1.

Chronic traumatic encephalopathy: clinical-biomarker correlations and current concepts in pathogenesis.

Gandy S, Ikonomovic MD, Mitsis E, Elder G, Ahlers ST, Barth J, Stone JR, DeKosky ST.

Mol Neurodegener. 2014 Sep 17;9:37. doi: 10.1186/1750-1326-9-37.

PMID:
25231386
[PubMed - in process]
Free Article
2.

Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions.

Ortiz-Virumbrales M, Ruiz M, Hone E, Dolios G, Wang R, Morant A, Kottwitz J, Ozelius LJ, Gandy S, Ehrlich ME.

Acta Neuropathol Commun. 2014 Sep 18;2(1):139. [Epub ahead of print]

PMID:
25231164
[PubMed - as supplied by publisher]
Free PMC Article
3.

Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury.

Mitsis EM, Riggio S, Kostakoglu L, Dickstein DL, Machac J, Delman B, Goldstein M, Jennings D, D'Antonio E, Martin J, Naidich TP, Aloysi A, Fernandez C, Seibyl J, DeKosky ST, Elder GA, Marek K, Gordon W, Hof PR, Sano M, Gandy S.

Transl Psychiatry. 2014 Sep 16;4:e441. doi: 10.1038/tp.2014.91.

PMID:
25226550
[PubMed - in process]
4.

Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse.

Kim SH, Steele JW, Lee SW, Clemenson GD, Carter TA, Treuner K, Gadient R, Wedel P, Glabe C, Barlow C, Ehrlich ME, Gage FH, Gandy S.

Mol Psychiatry. 2014 Aug 12. doi: 10.1038/mp.2014.87. [Epub ahead of print]

PMID:
25113378
[PubMed - as supplied by publisher]
5.

Pentameric Thiophene-Based Ligands that Spectrally Discriminate Amyloid-β and Tau Aggregates Display Distinct Solvatochromism and Viscosity-Induced Spectral Shifts.

Simon RA, Shirani H, Aslund KO, Bäck M, Haroutunian V, Gandy S, Nilsson KP.

Chemistry. 2014 Sep 22;20(39):12537-43. doi: 10.1002/chem.201402890. Epub 2014 Aug 8.

PMID:
25111601
[PubMed - in process]
6.

Alzheimer disease risk factors--reply.

DeKosky ST, Gandy S.

JAMA Neurol. 2014 Aug;71(8):1051-2. doi: 10.1001/jamaneurol.2014.636. No abstract available.

PMID:
25111207
[PubMed - in process]
7.

Common carotid intima media thickness and ankle-brachial pressure index correlate with local but not global atheroma burden: a cross sectional study using whole body magnetic resonance angiography.

Weir-McCall JR, Khan F, Lambert MA, Adamson CL, Gardner M, Gandy SJ, Ramkumar PG, Belch JJ, Struthers AD, Rauchhaus P, Morris AD, Houston JG.

PLoS One. 2014 Jun 16;9(6):e99190. doi: 10.1371/journal.pone.0099190. eCollection 2014.

PMID:
24933122
[PubMed - in process]
Free PMC Article
8.

Immunomodulation and AD--down but not out.

Knight EM, Gandy S.

J Clin Immunol. 2014 Jul;34 Suppl 1:S70-3. doi: 10.1007/s10875-014-0039-y. Epub 2014 Apr 30.

PMID:
24781637
[PubMed - in process]
9.

Alzheimer's disease research and development: a call for a new research roadmap.

Feldman HH, Haas M, Gandy S, Schoepp DD, Cross AJ, Mayeux R, Sperling RA, Fillit H, van de Hoef DL, Dougal S, Nye JS; One Mind for Research and the New York Academy of Sciences.

Ann N Y Acad Sci. 2014 Apr;1313:1-16. doi: 10.1111/nyas.12424.

PMID:
24754377
[PubMed - indexed for MEDLINE]
10.

A consecutive case series experience with [18 F] florbetapir PET imaging in an urban dementia center: impact on quality of life, decision making, and disposition.

Mitsis EM, Bender HA, Kostakoglu L, Machac J, Martin J, Woehr JL, Sewell MC, Aloysi A, Goldstein MA, Li C, Sano M, Gandy S.

Mol Neurodegener. 2014 Feb 3;9:10. doi: 10.1186/1750-1326-9-10.

PMID:
24484858
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Environmental exposures and the risk for Alzheimer disease: can we identify the smoking guns?

Dekosky ST, Gandy S.

JAMA Neurol. 2014 Mar;71(3):273-5. doi: 10.1001/jamaneurol.2013.6031. No abstract available.

PMID:
24473699
[PubMed - indexed for MEDLINE]
12.

Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial.

Witham MD, Ireland S, Houston JG, Gandy SJ, Waugh S, Macdonald TM, Mackenzie IS, Struthers AD.

Hypertension. 2014 Apr;63(4):706-12. doi: 10.1161/HYPERTENSIONAHA.113.02177. Epub 2014 Jan 13.

PMID:
24420547
[PubMed - indexed for MEDLINE]
13.

Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors.

Sproul AA, Jacob S, Pre D, Kim SH, Nestor MW, Navarro-Sobrino M, Santa-Maria I, Zimmer M, Aubry S, Steele JW, Kahler DJ, Dranovsky A, Arancio O, Crary JF, Gandy S, Noggle SA.

PLoS One. 2014 Jan 8;9(1):e84547. doi: 10.1371/journal.pone.0084547. eCollection 2014.

PMID:
24416243
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model.

Steele JW, Brautigam H, Short JA, Sowa A, Shi M, Yadav A, Weaver CM, Westaway D, Fraser PE, St George-Hyslop PH, Gandy S, Hof PR, Dickstein DL.

J Comp Neurol. 2014 Jul 1;522(10):2319-35. doi: 10.1002/cne.23536.

PMID:
24415002
[PubMed - in process]
15.

Alzheimer's disease: new data highlight nonneuronal cell types and the necessity for presymptomatic prevention strategies.

Gandy S.

Biol Psychiatry. 2014 Apr 1;75(7):553-7. doi: 10.1016/j.biopsych.2013.11.019. Epub 2013 Nov 28.

PMID:
24373429
[PubMed - in process]
Free PMC Article
16.

Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases.

Bharadwaj PR, Bates KA, Porter T, Teimouri E, Perry G, Steele JW, Gandy S, Groth D, Martins RN, Verdile G.

Transl Psychiatry. 2013 Dec 3;3:e332. doi: 10.1038/tp.2013.97. Review.

PMID:
24301650
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Reduction of synaptojanin 1 accelerates Aβ clearance and attenuates cognitive deterioration in an Alzheimer mouse model.

Zhu L, Zhong M, Zhao J, Rhee H, Caesar I, Knight EM, Volpicelli-Daley L, Bustos V, Netzer W, Liu L, Lucast L, Ehrlich ME, Robakis NK, Gandy SE, Cai D.

J Biol Chem. 2013 Nov 1;288(44):32050-63. doi: 10.1074/jbc.M113.504365. Epub 2013 Sep 19.

PMID:
24052255
[PubMed - indexed for MEDLINE]
18.

Allopurinol reduces left ventricular mass in patients with type 2 diabetes and left ventricular hypertrophy.

Szwejkowski BR, Gandy SJ, Rekhraj S, Houston JG, Lang CC, Morris AD, George J, Struthers AD.

J Am Coll Cardiol. 2013 Dec 17;62(24):2284-93. doi: 10.1016/j.jacc.2013.07.074. Epub 2013 Aug 28.

PMID:
23994420
[PubMed - indexed for MEDLINE]
19.

Microglia as dynamic and essential components of the amyloid hypothesis.

Gandy S, Heppner FL.

Neuron. 2013 May 22;78(4):575-7. doi: 10.1016/j.neuron.2013.05.007. No abstract available.

PMID:
23719156
[PubMed - indexed for MEDLINE]
Free Article
20.

Protein sorting motifs in the cytoplasmic tail of SorCS1 control generation of Alzheimer's amyloid-β peptide.

Lane RF, Steele JW, Cai D, Ehrlich ME, Attie AD, Gandy S.

J Neurosci. 2013 Apr 17;33(16):7099-107. doi: 10.1523/JNEUROSCI.5270-12.2013.

PMID:
23595767
[PubMed - indexed for MEDLINE]
Free PMC Article

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