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Items: 1 to 20 of 66

1.

Ca(II) Binding Regulates and Dominates the Reactivity of a Transition-Metal-Ion-Dependent Diesterase from Mycobacterium tuberculosis.

Pedroso MM, Larrabee JA, Ely F, Gwee SE, Mitić N, Ollis DL, Gahan LR, Schenk G.

Chemistry. 2016 Jan;22(3):999-1009. doi: 10.1002/chem.201504001. Epub 2015 Dec 14.

PMID:
26662456
2.

Selective Coordination of Gallium(III), Zinc(II), and Copper(II) by an Asymmetric Dinucleating Ligand: A Model for Metallophosphatases.

Bosch S, Comba P, Gahan LR, Hanson GR, Noble C, Schenk G, Wadepohl H.

Chemistry. 2015 Dec 7;21(50):18269-79. doi: 10.1002/chem.201503348. Epub 2015 Nov 18.

PMID:
26577705
3.

An Approach to More Accurate Model Systems for Purple Acid Phosphatases (PAPs).

Bernhardt PV, Bosch S, Comba P, Gahan LR, Hanson GR, Mereacre V, Noble CJ, Powell AK, Schenk G, Wadepohl H.

Inorg Chem. 2015 Aug 3;54(15):7249-63. doi: 10.1021/acs.inorgchem.5b00628. Epub 2015 Jul 21.

PMID:
26196255
4.

Altering the substrate specificity of methyl parathion hydrolase with directed evolution.

Ng TK, Gahan LR, Schenk G, Ollis DL.

Arch Biochem Biophys. 2015 May 1;573:59-68. doi: 10.1016/j.abb.2015.03.012. Epub 2015 Mar 19.

PMID:
25797441
5.

Dinuclear zinc(II) complexes with hydrogen bond donors as structural and functional phosphatase models.

Bosch S, Comba P, Gahan LR, Schenk G.

Inorg Chem. 2014 Sep 2;53(17):9036-51. doi: 10.1021/ic5009945. Epub 2014 Aug 14.

PMID:
25119813
6.

Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH).

Pedroso MM, Ely F, Mitić N, Carpenter MC, Gahan LR, Wilcox DE, Larrabee JL, Ollis DL, Schenk G.

J Biol Inorg Chem. 2014 Dec;19(8):1263-75. doi: 10.1007/s00775-014-1183-9. Epub 2014 Aug 8.

PMID:
25104333
7.

Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry.

Pedroso MM, Ely F, Lonhienne T, Gahan LR, Ollis DL, Guddat LW, Schenk G.

J Biol Inorg Chem. 2014 Mar;19(3):389-98. doi: 10.1007/s00775-013-1079-0. Epub 2014 Jan 12.

PMID:
24414447
8.

Carbonic anhydrase activity of dinuclear Cu(II) complexes with patellamide model ligands.

Comba P, Gahan LR, Hanson GR, Maeder M, Westphal M.

Dalton Trans. 2014 Feb 28;43(8):3144-52. doi: 10.1039/c3dt53135j.

PMID:
24326405
9.

Immobilization of the enzyme GpdQ on magnetite nanoparticles for organophosphate pesticide bioremediation.

Daumann LJ, Larrabee JA, Ollis D, Schenk G, Gahan LR.

J Inorg Biochem. 2014 Feb;131:1-7. doi: 10.1016/j.jinorgbio.2013.10.007. Epub 2013 Oct 16.

PMID:
24239906
10.

Cyclic peptide marine metabolites and CuII.

Comba P, Dovalil N, Gahan LR, Hanson GR, Westphal M.

Dalton Trans. 2014 Feb 7;43(5):1935-56. doi: 10.1039/c3dt52664j. Review.

PMID:
24202205
11.

Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes.

Daumann LJ, Schenk G, Ollis DL, Gahan LR.

Dalton Trans. 2014 Jan 21;43(3):910-28. doi: 10.1039/c3dt52287c. Epub 2013 Oct 18. Review.

PMID:
24135968
12.

Asymmetric zinc(II) complexes as functional and structural models for phosphoesterases.

Daumann LJ, Marty L, Schenk G, Gahan LR.

Dalton Trans. 2013 Jul 14;42(26):9574-84. doi: 10.1039/c3dt50514f. Epub 2013 May 15.

PMID:
23674062
13.

Synthesis, magnetic properties, and phosphoesterase activity of dinuclear cobalt(II) complexes.

Daumann LJ, Comba P, Larrabee JA, Schenk G, Stranger R, Cavigliasso G, Gahan LR.

Inorg Chem. 2013 Feb 18;52(4):2029-43. doi: 10.1021/ic302418x. Epub 2013 Feb 1.

PMID:
23374019
14.

Spectroscopic characterization of the active Fe(III)Fe(III) and Fe(III)Fe(II) forms of a purple acid phosphatase model system.

Comba P, Gahan LR, Mereacre V, Hanson GR, Powell AK, Schenk G, Zajaczkowski-Fischer M.

Inorg Chem. 2012 Nov 19;51(22):12195-209. doi: 10.1021/ic301347t. Epub 2012 Oct 30.

PMID:
23110717
15.

Phosphatase reactivity of a dicopper(II) complex of a patellamide derivative--possible biological functions of cyclic pseudopeptides.

Comba P, Gahan LR, Hanson GR, Westphal M.

Chem Commun (Camb). 2012 Sep 28;48(75):9364-6. doi: 10.1039/c2cc34836e. Epub 2012 Aug 15.

PMID:
22892984
16.

Cadmium(II) complexes: mimics of organophosphate pesticide degrading enzymes and metallo-β-lactamases.

Daumann LJ, Gahan LR, Comba P, Schenk G.

Inorg Chem. 2012 Jul 16;51(14):7669-81. doi: 10.1021/ic300687y. Epub 2012 Jul 3.

PMID:
22758396
17.

Binuclear metallohydrolases: complex mechanistic strategies for a simple chemical reaction.

Schenk G, Mitić N, Gahan LR, Ollis DL, McGeary RP, Guddat LW.

Acc Chem Res. 2012 Sep 18;45(9):1593-603. Epub 2012 Jun 14. Review.

PMID:
22698580
18.

Promiscuity comes at a price: catalytic versatility vs efficiency in different metal ion derivatives of the potential bioremediator GpdQ.

Daumann LJ, McCarthy BY, Hadler KS, Murray TP, Gahan LR, Larrabee JA, Ollis DL, Schenk G.

Biochim Biophys Acta. 2013 Jan;1834(1):425-32. doi: 10.1016/j.bbapap.2012.02.004. Epub 2012 Feb 15.

PMID:
22366468
19.

Spectroscopic and catalytic characterization of a functional Fe(III)Fe(II) biomimetic for the active site of uteroferrin and protein cleavage.

Smith SJ, Peralta RA, Jovito R, Horn A Jr, Bortoluzzi AJ, Noble CJ, Hanson GR, Stranger R, Jayaratne V, Cavigliasso G, Gahan LR, Schenk G, Nascimento OR, Cavalett A, Bortolotto T, Razzera G, Terenzi H, Neves A, Riley MJ.

Inorg Chem. 2012 Feb 20;51(4):2065-78. doi: 10.1021/ic201711p. Epub 2012 Jan 30.

PMID:
22289382
20.

Cu(II) coordination chemistry of patellamide derivatives: possible biological functions of cyclic pseudopeptides.

Comba P, Dovalil N, Gahan LR, Haberhauer G, Hanson GR, Noble CJ, Seibold B, Vadivelu P.

Chemistry. 2012 Feb 27;18(9):2578-90. doi: 10.1002/chem.201101975. Epub 2012 Jan 20.

PMID:
22266951
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