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Advances and unmet needs in genetic, basic and clinical science in Alport syndrome: report from the 2015 International Workshop on Alport Syndrome.

Gross O, Kashtan CE, Rheault MN, Flinter F, Savige J, Miner JH, Torra R, Ars E, Deltas C, Savva I, Perin L, Renieri A, Ariani F, Mari F, Baigent C, Judge P, Knebelman B, Heidet L, Lagas S, Blatt D, Ding J, Zhang Y, Gale DP, Prunotto M, Xue Y, Schachter AD, Morton LC, Blem J, Huang M, Liu S, Vallee S, Renault D, Schifter J, Skelding J, Gear S, Friede T, Turner AN, Lennon R.

Nephrol Dial Transplant. 2016 May 10. pii: gfw095. [Epub ahead of print] Review.


Prediction of Appropriate Shocks Using 24-Hour Holter Variables and T-Wave Alternans After First Implantable Cardioverter-Defibrillator Implantation in Patients With Ischemic or Nonischemic Cardiomyopathy.

Seegers J, Bergau L, Expósito PM, Bauer A, Fischer TH, Lüthje L, Hasenfuß G, Friede T, Zabel M.

Am J Cardiol. 2016 Apr 22. pii: S0002-9149(16)30497-0. doi: 10.1016/j.amjcard.2016.04.016. [Epub ahead of print]


Monitoring of 30 marker candidates in early Parkinson disease as progression markers.

Mollenhauer B, Zimmermann J, Sixel-Döring F, Focke NK, Wicke T, Ebentheuer J, Schaumburg M, Lang E, Trautmann E, Zetterberg H, Taylor P, Friede T, Trenkwalder C; DeNoPa Study Group.

Neurology. 2016 May 6. pii: 10.1212/WNL.0000000000002651. [Epub ahead of print]


Peripheral Nerve Dysfunction in Middle-Aged Subjects Born with Thalidomide Embryopathy.

Nicotra A, Newman C, Johnson M, Eremin O, Friede T, Malik O, Nicholas R.

PLoS One. 2016 Apr 21;11(4):e0152902. doi: 10.1371/journal.pone.0152902. eCollection 2016.


Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions.

Unkel S, Röver C, Stallard N, Benda N, Posch M, Zohar S, Friede T.

Orphanet J Rare Dis. 2016 Feb 20;11:16. doi: 10.1186/s13023-016-0402-6.


Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis.

Metz I, Beißbarth T, Ellenberger D, Pache F, Stork L, Ringelstein M, Aktas O, Jarius S, Wildemann B, Dihazi H, Friede T, Brück W, Ruprecht K, Paul F.

Neurol Neuroimmunol Neuroinflamm. 2016 Feb 2;3(2):e204. doi: 10.1212/NXI.0000000000000204. eCollection 2016 Apr.


Sex difference in appropriate shocks but not mortality during long-term follow-up in patients with implantable cardioverter-defibrillators.

Seegers J, Conen D, Jung K, Bergau L, Dorenkamp M, Lüthje L, Sohns C, Sossalla ST, Fischer TH, Hasenfuss G, Friede T, Zabel M.

Europace. 2015 Nov 29. pii: euv361. [Epub ahead of print]


Hartung-Knapp-Sidik-Jonkman approach and its modification for random-effects meta-analysis with few studies.

Röver C, Knapp G, Friede T.

BMC Med Res Methodol. 2015 Nov 14;15:99. doi: 10.1186/s12874-015-0091-1.


Baseline CSF/Serum-Ratio of Apolipoprotein E and Rate of Differential Decline in Alzheimer's Disease.

Schmidt C, Gerlach N, Schmitz M, Thom T, Kramer K, Friede T, Zerr I.

J Alzheimers Dis. 2015;48(1):189-96. doi: 10.3233/JAD-150286.


Design and analysis of three-arm trials with negative binomially distributed endpoints.

Mütze T, Munk A, Friede T.

Stat Med. 2016 Feb 20;35(4):505-21. doi: 10.1002/sim.6738. Epub 2015 Sep 21.


Methods for identification and confirmation of targeted subgroups in clinical trials: A systematic review.

Ondra T, Dmitrienko A, Friede T, Graf A, Miller F, Stallard N, Posch M.

J Biopharm Stat. 2016;26(1):99-119. doi: 10.1080/10543406.2015.1092034.


Changing EDSS Progression in Placebo Cohorts in Relapsing MS: A Systematic Review and Meta-Regression.

Röver C, Nicholas R, Straube S, Friede T.

PLoS One. 2015 Sep 1;10(9):e0137052. doi: 10.1371/journal.pone.0137052. eCollection 2015.


Scientific Versus Experiential Evidence: Discourse Analysis of the Chronic Cerebrospinal Venous Insufficiency Debate in a Multiple Sclerosis Forum.

Koschack J, Weibezahl L, Friede T, Himmel W, Makedonski P, Grabowski J.

J Med Internet Res. 2015 Jul 1;17(7):e159. doi: 10.2196/jmir.4103.


Flexible selection of a single treatment incorporating short-term endpoint information in a phase II/III clinical trial.

Stallard N, Kunz CU, Todd S, Parsons N, Friede T.

Stat Med. 2015 Oct 15;34(23):3104-15. doi: 10.1002/sim.6567. Epub 2015 Jun 26.


Memorandum "Open Metadata". Open Access to Documentation Forms and Item Catalogs in Healthcare.

Dugas M, Jöckel KH, Friede T, Gefeller O, Kieser M, Marschollek M, Ammenwerth E, Röhrig R, Knaup-Gregori P, Prokosch HU.

Methods Inf Med. 2015;54(4):376-8. doi: 10.3414/ME15-05-0007. Epub 2015 Jun 25.


Improving clinical trials for cardiovascular diseases: a position paper from the Cardiovascular Round Table of the European Society of Cardiology.

Jackson N, Atar D, Borentain M, Breithardt G, van Eickels M, Endres M, Fraass U, Friede T, Hannachi H, Janmohamed S, Kreuzer J, Landray M, Lautsch D, Le Floch C, Mol P, Naci H, Samani NJ, Svensson A, Thorstensen C, Tijssen J, Vandzhura V, Zalewski A, Kirchhof P.

Eur Heart J. 2016 Mar 1;37(9):747-54. doi: 10.1093/eurheartj/ehv213. Epub 2015 Jun 15. Review.


WITHDRAWN: Anticholinergics for urinary symptoms in multiple sclerosis.

Nicholas RS, Friede T, Hollis S, Young CA.

Cochrane Database Syst Rev. 2015 Jun 5;6:CD004193. doi: 10.1002/14651858.CD004193.pub3. Review. No abstract available.


A systematic review identifies shortcomings in the reporting of crossover trials in chronic painful conditions.

Straube S, Werny B, Friede T.

J Clin Epidemiol. 2015 Dec;68(12):1496-503. doi: 10.1016/j.jclinepi.2015.04.006. Epub 2015 Apr 30. Review.


Evidence synthesis for count distributions based on heterogeneous and incomplete aggregated data.

Röver C, Andreas S, Friede T.

Biom J. 2016 Jan;58(1):170-85. doi: 10.1002/bimj.201300288. Epub 2015 May 12.


Patients characteristics influencing the longitudinal utilization of steroids in multiple sclerosis--an observational study.

Rommer PS, Buckow K, Ellenberger D, Friede T, Pitschnau-Michel D, Fuge J, Stüve O, Zettl UK; German Multiple Sclerosis Registry of the German National MS Society.

Eur J Clin Invest. 2015 Jun;45(6):587-93. doi: 10.1111/eci.12450. Epub 2015 May 9.

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