Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 53

1.

Considerations for the successful co-development of targeted cancer therapies and companion diagnostics.

Fridlyand J, Simon RM, Walrath JC, Roach N, Buller R, Schenkein DP, Flaherty KT, Allen JD, Sigal EV, Scher HI.

Nat Rev Drug Discov. 2013 Oct;12(10):743-55. doi: 10.1038/nrd4101. Epub 2013 Sep 6.

PMID:
24008432
[PubMed - indexed for MEDLINE]
2.

An industry statistician's perspective on PHC drug development.

Fridlyand J, Yeh RF, Mackey H, Bengtsson T, Delmar P, Spaniolo G, Lieberman G.

Contemp Clin Trials. 2013 Nov;36(2):624-35. doi: 10.1016/j.cct.2013.04.006. Epub 2013 May 3. Review.

PMID:
23648396
[PubMed - indexed for MEDLINE]
3.

Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models.

Spoerke JM, O'Brien C, Huw L, Koeppen H, Fridlyand J, Brachmann RK, Haverty PM, Pandita A, Mohan S, Sampath D, Friedman LS, Ross L, Hampton GM, Amler LC, Shames DS, Lackner MR.

Clin Cancer Res. 2012 Dec 15;18(24):6771-83. doi: 10.1158/1078-0432.CCR-12-2347. Epub 2012 Nov 7.

PMID:
23136191
[PubMed - indexed for MEDLINE]
Free Article
4.

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.

Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J.

Nature. 2012 Jul 26;487(7408):505-9. doi: 10.1038/nature11249.

PMID:
22763448
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Analysis of tumor burden versus progression-free survival for Phase II decision making.

Fridlyand J, Kaiser LD, Fyfe G.

Contemp Clin Trials. 2011 May;32(3):446-52. doi: 10.1016/j.cct.2011.01.010. Epub 2011 Jan 23.

PMID:
21266203
[PubMed - indexed for MEDLINE]
6.

Statistical techniques to construct assays for identifying likely responders to a treatment under evaluation from cell line genomic data.

Huang EP, Fridlyand J, Lewin-Koh N, Yue P, Shi X, Dornan D, Burington B.

BMC Cancer. 2010 Oct 27;10:586. doi: 10.1186/1471-2407-10-586.

PMID:
20979617
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma.

Costa BM, Smith JS, Chen Y, Chen J, Phillips HS, Aldape KD, Zardo G, Nigro J, James CD, Fridlyand J, Reis RM, Costello JF.

Cancer Res. 2010 Jan 15;70(2):453-62. doi: 10.1158/0008-5472.CAN-09-2189. Epub 2010 Jan 12.

PMID:
20068170
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.

Hennessy BT, Gonzalez-Angulo AM, Stemke-Hale K, Gilcrease MZ, Krishnamurthy S, Lee JS, Fridlyand J, Sahin A, Agarwal R, Joy C, Liu W, Stivers D, Baggerly K, Carey M, Lluch A, Monteagudo C, He X, Weigman V, Fan C, Palazzo J, Hortobagyi GN, Nolden LK, Wang NJ, Valero V, Gray JW, Perou CM, Mills GB.

Cancer Res. 2009 May 15;69(10):4116-24. doi: 10.1158/0008-5472.CAN-08-3441. Epub 2009 May 12.

PMID:
19435916
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis.

Kwek SS, Roy R, Zhou H, Climent J, Martinez-Climent JA, Fridlyand J, Albertson DG.

Oncogene. 2009 Apr 30;28(17):1892-903. doi: 10.1038/onc.2009.34. Epub 2009 Mar 30.

PMID:
19330026
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Improving melanoma classification by integrating genetic and morphologic features.

Viros A, Fridlyand J, Bauer J, Lasithiotakis K, Garbe C, Pinkel D, Bastian BC.

PLoS Med. 2008 Jun 3;5(6):e120. doi: 10.1371/journal.pmed.0050120.

PMID:
18532874
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

High-resolution genomic and expression analyses of copy number alterations in breast tumors.

Haverty PM, Fridlyand J, Li L, Getz G, Beroukhim R, Lohr S, Wu TD, Cavet G, Zhang Z, Chant J.

Genes Chromosomes Cancer. 2008 Jun;47(6):530-42. doi: 10.1002/gcc.20558.

PMID:
18335499
[PubMed - indexed for MEDLINE]
12.

Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer.

Lee SA, Ho C, Roy R, Kosinski C, Patil MA, Tward AD, Fridlyand J, Chen X.

Hepatology. 2008 Apr;47(4):1200-10. doi: 10.1002/hep.22169.

PMID:
18214995
[PubMed - indexed for MEDLINE]
13.

Protein biomarker identification in the CSF of patients with CNS lymphoma.

Roy S, Josephson SA, Fridlyand J, Karch J, Kadoch C, Karrim J, Damon L, Treseler P, Kunwar S, Shuman MA, Jones T, Becker CH, Schulman H, Rubenstein JL.

J Clin Oncol. 2008 Jan 1;26(1):96-105. Epub 2007 Dec 3.

PMID:
18056677
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Evaluation of whole genome amplification protocols for array and oligonucleotide CGH.

Hittelman A, Sridharan S, Roy R, Fridlyand J, Loda M, Collins C, Paris PL.

Diagn Mol Pathol. 2007 Dec;16(4):198-206.

PMID:
18043282
[PubMed - indexed for MEDLINE]
15.

Acquired genomic aberrations associated with methotrexate resistance vary with background genomic instability.

Snijders AM, Hermsen MA, Baughman J, Buffart TE, Huey B, Gajduskova P, Roydasgupta R, Tokuyasu T, Meijer GA, Fridlyand J, Albertson DG.

Genes Chromosomes Cancer. 2008 Jan;47(1):71-83.

PMID:
17943968
[PubMed - indexed for MEDLINE]
16.

Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer.

Guan Y, Kuo WL, Stilwell JL, Takano H, Lapuk AV, Fridlyand J, Mao JH, Yu M, Miller MA, Santos JL, Kalloger SE, Carlson JW, Ginzinger DG, Celniker SE, Mills GB, Huntsman DG, Gray JW.

Clin Cancer Res. 2007 Oct 1;13(19):5745-55.

PMID:
17908964
[PubMed - indexed for MEDLINE]
Free Article
17.

Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers.

Yau C, Fedele V, Roydasgupta R, Fridlyand J, Hubbard A, Gray JW, Chew K, Dairkee SH, Moore DH, Schittulli F, Tommasi S, Paradiso A, Albertson DG, Benz CC.

Breast Cancer Res. 2007;9(5):R59.

PMID:
17850661
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Novel risk stratification of patients with neuroblastoma by genomic signature, which is independent of molecular signature.

Tomioka N, Oba S, Ohira M, Misra A, Fridlyand J, Ishii S, Nakamura Y, Isogai E, Hirata T, Yoshida Y, Todo S, Kaneko Y, Albertson DG, Pinkel D, Feuerstein BG, Nakagawara A.

Oncogene. 2008 Jan 17;27(4):441-9. Epub 2007 Jul 16.

PMID:
17637744
[PubMed - indexed for MEDLINE]
19.

FBXW7 and DNA copy number instability.

Byrd KN, Huey B, Roydasgupta R, Fridlyand J, Snijders AM, Albertson DG.

Breast Cancer Res Treat. 2008 May;109(1):47-54. Epub 2007 Jun 23.

PMID:
17588203
[PubMed - indexed for MEDLINE]
20.

Genome position and gene amplification.

Gajduskova P, Snijders AM, Kwek S, Roydasgupta R, Fridlyand J, Tokuyasu T, Pinkel D, Albertson DG.

Genome Biol. 2007;8(6):R120.

PMID:
17584934
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk