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Results: 1 to 20 of 132

1.

Intranasally-administered deferoxamine mitigates toxicity of 6-OHDA in a rat model of Parkinson׳s disease.

Fine JM, Forsberg AC, Renner DB, Faltesek KA, Mohan KG, Wong JC, Arneson LC, Crow JM, Frey WH 2nd, Hanson LR.

Brain Res. 2014 Jul 29;1574:96-104. doi: 10.1016/j.brainres.2014.05.048. Epub 2014 Jun 10.

PMID:
24928620
[PubMed - in process]
2.

Intranasal insulin to treat and protect against posttraumatic stress disorder.

Frey WH 2nd.

J Nerv Ment Dis. 2013 Jul;201(7):638-9. doi: 10.1097/NMD.0b013e318298302e. Review. No abstract available.

PMID:
23817163
[PubMed - indexed for MEDLINE]
3.

Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence.

Freiherr J, Hallschmid M, Frey WH 2nd, Brünner YF, Chapman CD, Hölscher C, Craft S, De Felice FG, Benedict C.

CNS Drugs. 2013 Jul;27(7):505-14. doi: 10.1007/s40263-013-0076-8. Review.

PMID:
23719722
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Intranasal delivery of insulin via the olfactory nerve pathway.

Renner DB, Svitak AL, Gallus NJ, Ericson ME, Frey WH 2nd, Hanson LR.

J Pharm Pharmacol. 2012 Dec;64(12):1709-14. doi: 10.1111/j.2042-7158.2012.01555.x. Epub 2012 Jul 4.

PMID:
23146033
[PubMed - indexed for MEDLINE]
5.

Intranasal treatment of central nervous system dysfunction in humans.

Chapman CD, Frey WH 2nd, Craft S, Danielyan L, Hallschmid M, Schiöth HB, Benedict C.

Pharm Res. 2013 Oct;30(10):2475-84. doi: 10.1007/s11095-012-0915-1. Epub 2012 Nov 8. Review.

PMID:
23135822
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Intranasal deferoxamine improves performance in radial arm water maze, stabilizes HIF-1α, and phosphorylates GSK3β in P301L tau transgenic mice.

Fine JM, Baillargeon AM, Renner DB, Hoerster NS, Tokarev J, Colton S, Pelleg A, Andrews A, Sparley KA, Krogh KM, Frey WH, Hanson LR.

Exp Brain Res. 2012 Jun;219(3):381-90. doi: 10.1007/s00221-012-3101-0. Epub 2012 May 1.

PMID:
22547371
[PubMed - indexed for MEDLINE]
7.

Lysosomal enzyme can bypass the blood-brain barrier and reach the CNS following intranasal administration.

Wolf DA, Hanson LR, Aronovich EL, Nan Z, Low WC, Frey WH 2nd, McIvor RS.

Mol Genet Metab. 2012 May;106(1):131-4. doi: 10.1016/j.ymgme.2012.02.006. Epub 2012 Feb 10.

PMID:
22420937
[PubMed - indexed for MEDLINE]
8.

Intranasal delivery of siRNA to the olfactory bulbs of mice via the olfactory nerve pathway.

Renner DB, Frey WH 2nd, Hanson LR.

Neurosci Lett. 2012 Apr 4;513(2):193-7. doi: 10.1016/j.neulet.2012.02.037. Epub 2012 Feb 22.

PMID:
22387067
[PubMed - indexed for MEDLINE]
9.

Intranasal delivery of growth differentiation factor 5 to the central nervous system.

Hanson LR, Fine JM, Hoekman JD, Nguyen TM, Burns RB, Martinez PM, Pohl J, Frey WH 2nd.

Drug Deliv. 2012 Apr;19(3):149-54. doi: 10.3109/10717544.2012.657720. Epub 2012 Feb 22.

PMID:
22353012
[PubMed - indexed for MEDLINE]
10.

Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states.

Martinez JA, Kasamatsu M, Rosales-Hernandez A, Hanson LR, Frey WH, Toth CC.

Mol Pain. 2012 Jan 11;8:3. doi: 10.1186/1744-8069-8-3. Retraction in: Mol Pain. 2014;10:20.

PMID:
22236461
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Brain insulin signaling and Alzheimer's disease: current evidence and future directions.

Schiöth HB, Craft S, Brooks SJ, Frey WH 2nd, Benedict C.

Mol Neurobiol. 2012 Aug;46(1):4-10. doi: 10.1007/s12035-011-8229-6. Epub 2011 Dec 29. Review.

PMID:
22205300
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Intranasal treatment of neurodegenerative diseases and stroke.

Gomez D, Martinez JA, Hanson LR, Frey WH 2nd, Toth CC.

Front Biosci (Schol Ed). 2012 Jan 1;4:74-89. Review.

PMID:
22202044
[PubMed - indexed for MEDLINE]
13.

Insulin to treat Alzheimer's disease: just follow your nose?

Schiöth HB, Frey WH, Brooks SJ, Benedict C.

Expert Rev Clin Pharmacol. 2012 Jan;5(1):17-20. doi: 10.1586/ecp.11.70.

PMID:
22142155
[PubMed]
14.

Subacute intranasal administration of tissue plasminogen activator increases functional recovery and axonal remodeling after stroke in rats.

Liu Z, Li Y, Zhang L, Xin H, Cui Y, Hanson LR, Frey WH 2nd, Chopp M.

Neurobiol Dis. 2012 Feb;45(2):804-9. doi: 10.1016/j.nbd.2011.11.004. Epub 2011 Nov 15.

PMID:
22115941
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke.

Akpan N, Serrano-Saiz E, Zacharia BE, Otten ML, Ducruet AF, Snipas SJ, Liu W, Velloza J, Cohen G, Sosunov SA, Frey WH 2nd, Salvesen GS, Connolly ES Jr, Troy CM.

J Neurosci. 2011 Jun 15;31(24):8894-904. doi: 10.1523/JNEUROSCI.0698-11.2011.

PMID:
21677173
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Motor end plate innervation loss in diabetes and the role of insulin.

Francis GJ, Martinez JA, Liu WQ, Zochodne DW, Hanson LR, Frey WH 2nd, Toth C.

J Neuropathol Exp Neurol. 2011 May;70(5):323-39. doi: 10.1097/NEN.0b013e318215669a.

PMID:
21487310
[PubMed - indexed for MEDLINE]
17.

Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease.

Danielyan L, Schäfer R, von Ameln-Mayerhofer A, Bernhard F, Verleysdonk S, Buadze M, Lourhmati A, Klopfer T, Schaumann F, Schmid B, Koehle C, Proksch B, Weissert R, Reichardt HM, van den Brandt J, Buniatian GH, Schwab M, Gleiter CH, Frey WH 2nd.

Rejuvenation Res. 2011 Feb;14(1):3-16. doi: 10.1089/rej.2010.1130. Epub 2011 Feb 3.

PMID:
21291297
[PubMed - indexed for MEDLINE]
18.

Intranasal phosphoramidon increases beta-amyloid levels in wild-type and NEP/NEP2-deficient mice.

Hanson LR, Hafez D, Svitak AL, Burns RB, Li X, Frey WH 2nd, Marr RA.

J Mol Neurosci. 2011 Mar;43(3):424-7. doi: 10.1007/s12031-010-9460-8. Epub 2010 Oct 13.

PMID:
20941644
[PubMed - indexed for MEDLINE]
19.

Intranasal insulin as a therapeutic option in the treatment of cognitive impairments.

Benedict C, Frey WH 2nd, Schiöth HB, Schultes B, Born J, Hallschmid M.

Exp Gerontol. 2011 Feb-Mar;46(2-3):112-5. doi: 10.1016/j.exger.2010.08.026. Epub 2010 Sep 16. Review.

PMID:
20849944
[PubMed - indexed for MEDLINE]
20.

Trigeminal pathways deliver a low molecular weight drug from the nose to the brain and orofacial structures.

Johnson NJ, Hanson LR, Frey WH.

Mol Pharm. 2010 Jun 7;7(3):884-93. doi: 10.1021/mp100029t.

PMID:
20420446
[PubMed - indexed for MEDLINE]
Free PMC Article

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