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Results: 1 to 20 of 33

1.

Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 update.

Martin MA, Hoffman JM, Freimuth RR, Klein TE, Dong BJ, Pirmohamed M, Hicks JK, Wilkinson MR, Haas DW, Kroetz DL; Clinical Pharmacogenetics Implementation Consortium.

Clin Pharmacol Ther. 2014 May;95(5):499-500. doi: 10.1038/clpt.2014.38. Epub 2014 Feb 21.

PMID:
24561393
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A Weighted Random Forests Approach to Improve Predictive Performance.

Winham SJ, Freimuth RR, Biernacka JM.

Stat Anal Data Min. 2013 Dec 1;6(6):496-505.

PMID:
24501613
[PubMed]
Free PMC Article
3.

Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process.

Caudle KE, Klein TE, Hoffman JM, Muller DJ, Whirl-Carrillo M, Gong L, McDonagh EM, Sangkuhl K, Thorn CF, Schwab M, Agundez JA, Freimuth RR, Huser V, Lee MT, Iwuchukwu OF, Crews KR, Scott SA, Wadelius M, Swen JJ, Tyndale RF, Stein CM, Roden D, Relling MV, Williams MS, Johnson SG.

Curr Drug Metab. 2014 Feb;15(2):209-17.

PMID:
24479687
[PubMed - in process]
Free PMC Article
4.

Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time-using genomic data to individualize treatment protocol.

Bielinski SJ, Olson JE, Pathak J, Weinshilboum RM, Wang L, Lyke KJ, Ryu E, Targonski PV, Van Norstrand MD, Hathcock MA, Takahashi PY, McCormick JB, Johnson KJ, Maschke KJ, Rohrer Vitek CR, Ellingson MS, Wieben ED, Farrugia G, Morrisette JA, Kruckeberg KJ, Bruflat JK, Peterson LM, Blommel JH, Skierka JM, Ferber MJ, Black JL, Baudhuin LM, Klee EW, Ross JL, Veldhuizen TL, Schultz CG, Caraballo PJ, Freimuth RR, Chute CG, Kullo IJ.

Mayo Clin Proc. 2014 Jan;89(1):25-33. doi: 10.1016/j.mayocp.2013.10.021.

PMID:
24388019
[PubMed - indexed for MEDLINE]
5.

PharmGKB Drug Data Normalization with NDF-RT.

Zhu Q, Freimuth RR, Pathak J, Chute CG.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:180. eCollection 2013.

PMID:
24303334
[PubMed]
6.

Toward semantic modeling of pharmacogenomic knowledge for clinical and translational decision support.

Boyce RD, Freimuth RR, Romagnoli KM, Pummer T, Hochheiser H, Empey PE.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:28-32. eCollection 2013.

PMID:
24303292
[PubMed]
Free PMC Article
7.

Using clinical element models for pharmacogenomic study data standardization.

Zhu Q, Freimuth RR, Pathak J, Chute CG.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:292-6. eCollection 2013.

PMID:
24303283
[PubMed]
Free PMC Article
8.

Mining Genotype-Phenotype Associations from Public Knowledge Sources via Semantic Web Querying.

Kiefer RC, Freimuth RR, Chute CG, Pathak J.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:118-22. eCollection 2013.

PMID:
24303249
[PubMed]
Free PMC Article
9.

Making data on essential pharmacogenes available for every patient everywhere: the Medicine Safety Code initiative.

Samwald M, Freimuth RR.

Pharmacogenomics. 2013 Oct;14(13):1529-31. doi: 10.2217/pgs.13.121. No abstract available.

PMID:
24088121
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Development and use of active clinical decision support for preemptive pharmacogenomics.

Bell GC, Crews KR, Wilkinson MR, Haidar CE, Hicks JK, Baker DK, Kornegay NM, Yang W, Cross SJ, Howard SC, Freimuth RR, Evans WE, Broeckel U, Relling MV, Hoffman JM.

J Am Med Inform Assoc. 2014 Feb;21(e1):e93-9. doi: 10.1136/amiajnl-2013-001993. Epub 2013 Aug 26.

PMID:
23978487
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Disambiguation of PharmGKB drug-disease relations with NDF-RT and SPL.

Zhu Q, Freimuth RR, Pathak J, Durski MJ, Chute CG.

J Biomed Inform. 2013 Aug;46(4):690-6. doi: 10.1016/j.jbi.2013.05.005. Epub 2013 May 29.

PMID:
23727027
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation.

Shuldiner AR, Relling MV, Peterson JF, Hicks JK, Freimuth RR, Sadee W, Pereira NL, Roden DM, Johnson JA, Klein TE; Pharmacogenomics Research Network Translational Pharmacogenetics Program Group, Shuldiner AR, Vesely M, Robinson SW, Ambulos N Jr, Stass SA, Kelemen MD, Brown LA, Pollin TI, Beitelshees AL, Zhao RY, Pakyz RE, Palmer K, Alestock T, O'Neill C, Maloney K, Branham A, Sewell D, Relling MV, Crews K, Hoffman J, Cross S, Haidar C, Baker D, Hicks JK, Bell G, Greeson F, Gaur A, Reiss U, Huettel A, Cheng C, Gajjar A, Pappo A, Howard S, Hudson M, Pui CH, Jeha S, Evans WE, Broeckel U, Altman RB, Gong L, Whirl-Carrillo M, Klein TE, Sadee W, Manickam K, Sweet KM, Embi PJ, Roden D, Peterson J, Denny J, Schildcrout J, Bowton E, Pulley J, Beller M, Mitchell J, Danciu I, Price L, Pereira NL, Weinshilboum R, Wang L, Johnson JA, Nelson D, Clare-Salzler M, Elsey A, Burkley B, Langaee T, Liu F, Nessl D, Dong HJ, Lesko L, Freimuth RR, Chute CG.

Clin Pharmacol Ther. 2013 Aug;94(2):207-10. doi: 10.1038/clpt.2013.59. Epub 2013 Mar 19. No abstract available.

PMID:
23588301
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A semantic-web oriented representation of the clinical element model for secondary use of electronic health records data.

Tao C, Jiang G, Oniki TA, Freimuth RR, Zhu Q, Sharma D, Pathak J, Huff SM, Chute CG.

J Am Med Inform Assoc. 2013 May 1;20(3):554-62. doi: 10.1136/amiajnl-2012-001326. Epub 2012 Dec 25.

PMID:
23268487
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Harmonization and semantic annotation of data dictionaries from the Pharmacogenomics Research Network: a case study.

Zhu Q, Freimuth RR, Lian Z, Bauer S, Pathak J, Tao C, Durski MJ, Chute CG.

J Biomed Inform. 2013 Apr;46(2):286-93. doi: 10.1016/j.jbi.2012.11.004. Epub 2012 Nov 29.

PMID:
23201637
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

SNP interaction detection with Random Forests in high-dimensional genetic data.

Winham SJ, Colby CL, Freimuth RR, Wang X, de Andrade M, Huebner M, Biernacka JM.

BMC Bioinformatics. 2012 Jul 15;13:164. doi: 10.1186/1471-2105-13-164.

PMID:
22793366
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Life sciences domain analysis model.

Freimuth RR, Freund ET, Schick L, Sharma MK, Stafford GA, Suzek BE, Hernandez J, Hipp J, Kelley JM, Rokicki K, Pan S, Buckler A, Stokes TH, Fernandez A, Fore I, Buetow KH, Klemm JD.

J Am Med Inform Assoc. 2012 Nov-Dec;19(6):1095-102. doi: 10.1136/amiajnl-2011-000763. Epub 2012 Jun 28.

PMID:
22744959
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Semantically enabling pharmacogenomic data for the realization of personalized medicine.

Samwald M, Coulet A, Huerga I, Powers RL, Luciano JS, Freimuth RR, Whipple F, Pichler E, Prud'hommeaux E, Dumontier M, Marshall MS.

Pharmacogenomics. 2012 Jan;13(2):201-12. doi: 10.2217/pgs.11.179. Review. Erratum in: Pharmacogenomics. 2012 Apr;13(5):628.

PMID:
22256869
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Integrating VA's NDF-RT drug terminology with PharmGKB: preliminary results.

Pathak J, Weiss LC, Durski MJ, Zhu Q, Freimuth RR, Chute CG.

Pac Symp Biocomput. 2012:400-9.

PMID:
22174295
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

caBIG compatibility review system: software to support the evaluation of applications using defined interoperability criteria.

Freimuth RR, Schauer MW, Lodha P, Govindrao P, Nagarajan R, Chute CG.

AMIA Annu Symp Proc. 2008 Nov 6:197-201.

PMID:
18999296
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

DNA methylotype analysis in colorectal cancer.

Yu J, Freimuth RR, Culverhouse R, Marsh S, Watson MA, McLeod HL.

Oncol Rep. 2008 Oct;20(4):921-7.

PMID:
18813836
[PubMed - indexed for MEDLINE]

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