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Results: 20

1.

Design and discovery of mushroom tyrosinase inhibitors and their therapeutic applications.

Mendes E, Perry Mde J, Francisco AP.

Expert Opin Drug Discov. 2014 May;9(5):533-54. doi: 10.1517/17460441.2014.907789. Epub 2014 Apr 7.

PMID:
24708040
[PubMed - in process]
2.

The YEASTRACT database: an upgraded information system for the analysis of gene and genomic transcription regulation in Saccharomyces cerevisiae.

Teixeira MC, Monteiro PT, Guerreiro JF, Gonçalves JP, Mira NP, dos Santos SC, Cabrito TR, Palma M, Costa C, Francisco AP, Madeira SC, Oliveira AL, Freitas AT, Sá-Correia I.

Nucleic Acids Res. 2014 Jan;42(Database issue):D161-6. doi: 10.1093/nar/gkt1015. Epub 2013 Oct 28.

PMID:
24170807
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Synthesis and evaluation of N-acylamino acids derivatives of triazenes. Activation by tyrosinase in human melanoma cell lines.

Monteiro AS, Almeida J, Cabral G, Severino P, Videira PA, Sousa A, Nunes R, Pereira JD, Francisco AP, Perry MJ, Mendes E.

Eur J Med Chem. 2013 Dec;70:1-9. doi: 10.1016/j.ejmech.2013.09.040. Epub 2013 Oct 2.

PMID:
24125877
[PubMed - in process]
4.

Assessing the molecular basis of transferable quinolone resistance in Escherichia coli and Salmonella spp. from food-producing animals and food products.

Jones-Dias D, Manageiro V, Francisco AP, Martins AP, Domingues G, Louro D, Ferreira E, Caniça M.

Vet Microbiol. 2013 Dec 27;167(3-4):523-31. doi: 10.1016/j.vetmic.2013.08.010. Epub 2013 Aug 22.

PMID:
24041769
[PubMed - indexed for MEDLINE]
5.

Targets, structures, and recent approaches in malignant melanoma chemotherapy.

Matos AM, Francisco AP.

ChemMedChem. 2013 Nov;8(11):1751-65. doi: 10.1002/cmdc.201300248. Epub 2013 Aug 16.

PMID:
23956078
[PubMed - in process]
6.

The multifactorial nature of Alzheimer's disease for developing potential therapeutics.

Carreiras MC, Mendes E, Perry MJ, Francisco AP, Marco-Contelles J.

Curr Top Med Chem. 2013;13(15):1745-70. Review.

PMID:
23931435
[PubMed - indexed for MEDLINE]
7.

In vitro antimicrobial activity of royleanone derivatives against Gram-positive bacterial pathogens.

Rijo P, Duarte A, Francisco AP, Semedo-Lemsaddek T, Simões MF.

Phytother Res. 2014 Jan;28(1):76-81. doi: 10.1002/ptr.4961. Epub 2013 Mar 11.

PMID:
23494919
[PubMed - indexed for MEDLINE]
8.

Interactogeneous: disease gene prioritization using heterogeneous networks and full topology scores.

Gonçalves JP, Francisco AP, Moreau Y, Madeira SC.

PLoS One. 2012;7(11):e49634. doi: 10.1371/journal.pone.0049634. Epub 2012 Nov 19.

PMID:
23185389
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Development of triazene prodrugs for ADEPT strategy: new insights into drug delivery system based on carboxypeptidase G2 activation.

Capucha V, Mendes E, Francisco AP, Perry MJ.

Bioorg Med Chem Lett. 2012 Nov 15;22(22):6903-8. doi: 10.1016/j.bmcl.2012.09.029. Epub 2012 Sep 18.

PMID:
23041157
[PubMed - indexed for MEDLINE]
10.

PHYLOViZ: phylogenetic inference and data visualization for sequence based typing methods.

Francisco AP, Vaz C, Monteiro PT, Melo-Cristino J, Ramirez M, Carriço JA.

BMC Bioinformatics. 2012 May 8;13:87. doi: 10.1186/1471-2105-13-87.

PMID:
22568821
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Regulatory Snapshots: integrative mining of regulatory modules from expression time series and regulatory networks.

Gonçalves JP, Aires RS, Francisco AP, Madeira SC.

PLoS One. 2012;7(5):e35977. doi: 10.1371/journal.pone.0035977. Epub 2012 May 1.

PMID:
22563474
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Pattern matching through Chaos Game Representation: bridging numerical and discrete data structures for biological sequence analysis.

Vinga S, Carvalho AM, Francisco AP, Russo LM, Almeida JS.

Algorithms Mol Biol. 2012 May 2;7(1):10. doi: 10.1186/1748-7188-7-10.

PMID:
22551152
[PubMed]
Free PMC Article
13.

TFRank: network-based prioritization of regulatory associations underlying transcriptional responses.

Gonçalves JP, Francisco AP, Mira NP, Teixeira MC, Sá-Correia I, Oliveira AL, Madeira SC.

Bioinformatics. 2011 Nov 15;27(22):3149-57. doi: 10.1093/bioinformatics/btr546. Epub 2011 Sep 29.

PMID:
21965816
[PubMed - indexed for MEDLINE]
Free Article
14.

YEASTRACT: providing a programmatic access to curated transcriptional regulatory associations in Saccharomyces cerevisiae through a web services interface.

Abdulrehman D, Monteiro PT, Teixeira MC, Mira NP, Lourenço AB, dos Santos SC, Cabrito TR, Francisco AP, Madeira SC, Aires RS, Oliveira AL, Sá-Correia I, Freitas AT.

Nucleic Acids Res. 2011 Jan;39(Database issue):D136-40. doi: 10.1093/nar/gkq964. Epub 2010 Oct 23.

PMID:
20972212
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Antimycobacterial metabolites from Plectranthus: royleanone derivatives against Mycobacterium tuberculosis strains.

Rijo P, Simões MF, Francisco AP, Rojas R, Gilman RH, Vaisberg AJ, Rodríguez B, Moiteiro C.

Chem Biodivers. 2010 Apr;7(4):922-32. doi: 10.1002/cbdv.200900099.

PMID:
20397225
[PubMed - indexed for MEDLINE]
16.

Global optimal eBURST analysis of multilocus typing data using a graphic matroid approach.

Francisco AP, Bugalho M, Ramirez M, Carriço JA.

BMC Bioinformatics. 2009 May 18;10:152. doi: 10.1186/1471-2105-10-152.

PMID:
19450271
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Dopamine- and tyramine-based derivatives of triazenes: activation by tyrosinase and implications for prodrug design.

Perry MJ, Mendes E, Simplício AL, Coelho A, Soares RV, Iley J, Moreira R, Francisco AP.

Eur J Med Chem. 2009 Aug;44(8):3228-34. doi: 10.1016/j.ejmech.2009.03.025. Epub 2009 Mar 27.

PMID:
19386398
[PubMed - indexed for MEDLINE]
18.

Vertebral coplanar alignment: a standardized technique for three dimensional correction in scoliosis surgery: technical description and preliminary results in Lenke type 1 curves.

Vallespir GP, Flores JB, Trigueros IS, Sierra EH, Fernández PD, Olaverri JC, Alonso MG, Galea RR, Francisco AP, Rodríguez de Paz B, Carbonell PG, Thomas JV, López JL, Paulino JI, Pitarque CB, García OR.

Spine (Phila Pa 1976). 2008 Jun 15;33(14):1588-97. doi: 10.1097/BRS.0b013e3181788704.

PMID:
18552675
[PubMed - indexed for MEDLINE]
19.

YEASTRACT-DISCOVERER: new tools to improve the analysis of transcriptional regulatory associations in Saccharomyces cerevisiae.

Monteiro PT, Mendes ND, Teixeira MC, d'Orey S, Tenreiro S, Mira NP, Pais H, Francisco AP, Carvalho AM, Lourenço AB, Sá-Correia I, Oliveira AL, Freitas AT.

Nucleic Acids Res. 2008 Jan;36(Database issue):D132-6. Epub 2007 Nov 21.

PMID:
18032429
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Triazene drug metabolites. Part 17: Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes.

Carvalho E, Francisco AP, Iley J, Rosa E.

Bioorg Med Chem. 2000 Jul;8(7):1719-25.

PMID:
10976519
[PubMed - indexed for MEDLINE]

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