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Results: 1 to 20 of 176

1.

TGF-β stimulation in human and murine cells reveals commonly affected biological processes and pathways at transcription level.

Abnaof K, Mallela N, Walenda G, Meurer SK, Seré K, Lin Q, Smeets B, Hoffmann K, Wagner W, Zenke M, Weiskirchen R, Fröhlich H.

BMC Syst Biol. 2014 May 15;8(1):55. doi: 10.1186/1752-0509-8-55.

PMID:
24886091
[PubMed - in process]
Free PMC Article
2.

Evidence for contribution of epigenetic mechanisms in the pathogenesis of systemic mast cell activation disease.

Haenisch B, Fröhlich H, Herms S, Molderings GJ.

Immunogenetics. 2014 May;66(5):287-97. doi: 10.1007/s00251-014-0768-3. Epub 2014 Mar 14.

PMID:
24622794
[PubMed - indexed for MEDLINE]
3.

netClass: an R-package for network based, integrative biomarker signature discovery.

Cun Y, Fröhlich H.

Bioinformatics. 2014 May 1;30(9):1325-6. doi: 10.1093/bioinformatics/btu025. Epub 2014 Jan 17.

PMID:
24443376
[PubMed - in process]
4.

Including network knowledge into Cox regression models for biomarker signature discovery.

Fröhlich H.

Biom J. 2014 Mar;56(2):287-306. doi: 10.1002/bimj.201300035. Epub 2014 Jan 15.

PMID:
24430933
[PubMed - in process]
5.

NSCLC cells adapted to EGFR inhibition accumulate EGFR interacting proteins and down-regulate microRNA related to epithelial-mesenchymal transition.

Mader RM, Foerster S, Sarin N, Michaelis M, Cinatl J Jr, Kloft C, Fröhlich H, Engel F, Kalayda GV, Jäger W, Frötschl R, Jaehde U, Ritter CA.

Int J Clin Pharmacol Ther. 2014 Jan;52(1):92-4. doi: 10.5414/CPXCES13EA08. No abstract available.

PMID:
24219969
[PubMed - indexed for MEDLINE]
6.

A systems pharmacology approach to improve drug therapy in NSCLC: establishing a CESAR network.

Kalayda GV, Michaelis M, Cinatl J Jr, Mader RM, Fröhlich H, Sarin N, Melin J, Engel F, Jäger W, Frötschl R, Jaehde U, Kloft C, Ritter CA.

Int J Clin Pharmacol Ther. 2014 Jan;52(1):89-91. doi: 10.5414/CPXCES13EA07. No abstract available.

PMID:
24216144
[PubMed - indexed for MEDLINE]
7.

TGF-beta1 does not induce senescence of multipotent mesenchymal stromal cells and has similar effects in early and late passages.

Walenda G, Abnaof K, Joussen S, Meurer S, Smeets H, Rath B, Hoffmann K, Fröhlich H, Zenke M, Weiskirchen R, Wagner W.

PLoS One. 2013 Oct 17;8(10):e77656. doi: 10.1371/journal.pone.0077656. eCollection 2013.

PMID:
24147049
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Unsupervised automated high throughput phenotyping of RNAi time-lapse movies.

Failmezger H, Fröhlich H, Tresch A.

BMC Bioinformatics. 2013 Oct 4;14:292. doi: 10.1186/1471-2105-14-292.

PMID:
24090185
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Stimulation of MMP-1 and CCL2 by NAMPT in PDL cells.

Nokhbehsaim M, Eick S, Nogueira AV, Hoffmann P, Herms S, Fröhlich H, Jepsen S, Jäger A, Cirelli JA, Deschner J.

Mediators Inflamm. 2013;2013:437123. doi: 10.1155/2013/437123. Epub 2013 Aug 22.

PMID:
24058270
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Network and data integration for biomarker signature discovery via network smoothed T-statistics.

Cun Y, Fröhlich H.

PLoS One. 2013 Sep 3;8(9):e73074. doi: 10.1371/journal.pone.0073074. eCollection 2013.

PMID:
24019896
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Boosting probabilistic graphical model inference by incorporating prior knowledge from multiple sources.

Praveen P, Fröhlich H.

PLoS One. 2013 Jun 24;8(6):e67410. doi: 10.1371/journal.pone.0067410. Print 2013.

PMID:
23826291
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Thrombin-sensitive expression of the store operated Ca(2+) channel Orai1 in platelets.

Münzer P, Tolios A, Pelzl L, Schmid E, Schmidt EM, Walker B, Fröhlich H, Borst O, Gawaz M, Lang F.

Biochem Biophys Res Commun. 2013 Jun 21;436(1):25-30. doi: 10.1016/j.bbrc.2013.05.031. Epub 2013 May 16.

PMID:
23685155
[PubMed - indexed for MEDLINE]
13.

Steiner tree methods for optimal sub-network identification: an empirical study.

Sadeghi A, Fröhlich H.

BMC Bioinformatics. 2013 Apr 30;14:144. doi: 10.1186/1471-2105-14-144.

PMID:
23627667
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit.

Chen Y, Siegel F, Kipschull S, Haas B, Fröhlich H, Meister G, Pfeifer A.

Nat Commun. 2013;4:1769. doi: 10.1038/ncomms2742.

PMID:
23612310
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Learning gene network structure from time laps cell imaging in RNAi Knock downs.

Failmezger H, Praveen P, Tresch A, Fröhlich H.

Bioinformatics. 2013 Jun 15;29(12):1534-40. doi: 10.1093/bioinformatics/btt179. Epub 2013 Apr 17.

PMID:
23595660
[PubMed - indexed for MEDLINE]
Free Article
16.

Predicting potent compounds via model-based global optimization.

Ahmadi M, Vogt M, Iyer P, Bajorath J, Fröhlich H.

J Chem Inf Model. 2013 Mar 25;53(3):553-9. doi: 10.1021/ci3004682. Epub 2013 Feb 14.

PMID:
23363236
[PubMed - in process]
17.

Immune system modeling and related pathologies.

Pappalardo F, Brusic V, Fröhlich H.

Comput Math Methods Med. 2012;2012:274702. doi: 10.1155/2012/274702. Epub 2012 Dec 17. No abstract available.

PMID:
23346220
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

MC EMiNEM maps the interaction landscape of the Mediator.

Niederberger T, Etzold S, Lidschreiber M, Maier KC, Martin DE, Fröhlich H, Cramer P, Tresch A.

PLoS Comput Biol. 2012;8(6):e1002568. doi: 10.1371/journal.pcbi.1002568. Epub 2012 Jun 21.

PMID:
22737066
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Joint Bayesian inference of condition-specific miRNA and transcription factor activities from combined gene and microRNA expression data.

Zacher B, Abnaof K, Gade S, Younesi E, Tresch A, Fröhlich H.

Bioinformatics. 2012 Jul 1;28(13):1714-20. doi: 10.1093/bioinformatics/bts257. Epub 2012 May 4.

PMID:
22563068
[PubMed - indexed for MEDLINE]
Free Article
20.

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