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Items: 1 to 20 of 47

1.

THE NEUTROPHIL RESPONSE INDUCED BY AN AGONIST FOR THE FREE FATTY ACID RECEPTOR 2 (FFA2R/GPR43) IS PRIMED BY TNF-α AND BY RECEPTOR UNCOUPLING FROM THE CYTOSKELETON BUT ATTENUATED BY TISSUE RECRUITMENT.

Björkman L, Mårtensson J, Winther M, Gabl M, Holdfeldt A, Uhrbom M, Bylund J, Højgaard Hansen A, Pandey SK, Ulven T, Forsman H, Dahlgren C.

Mol Cell Biol. 2016 Aug 8. pii: MCB.00161-16. [Epub ahead of print]

PMID:
27503855
2.

The lipidated peptidomimetic Lau-[(S)-Aoc]-(Lys-βNphe)6-NH2 is a novel formyl peptide receptor 2 agonist that activates both human and mouse neutrophil NADPH-oxidase.

Holdfeldt A, Skovbakke SL, Winther M, Gabl M, Nielsen C, Perez-Gassol I, Larsen CJ, Wang JM, Karlsson A, Dahlgren C, Forsman H, Franzyk H.

J Biol Chem. 2016 Jul 15. pii: jbc.M116.736850. [Epub ahead of print]

3.

Data on human neutrophil activation induced by pepducins with amino acid sequences derived from β2AR and CXCR4.

Holdfeldt A, Winther M, Gabl M, Dahlgren C, Forsman H.

Data Brief. 2016 Jun 1;8:411-4. doi: 10.1016/j.dib.2016.05.065. eCollection 2016 Sep.

4.

Does poor school performance cause later psychosocial problems among children in foster care? Evidence from national longitudinal registry data.

Forsman H, Brännström L, Vinnerljung B, Hjern A.

Child Abuse Negl. 2016 Jul;57:61-71. doi: 10.1016/j.chiabu.2016.06.006. Epub 2016 Jun 16.

PMID:
27318971
5.

Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria.

Dahlgren C, Gabl M, Holdfeldt A, Winther M, Forsman H.

Biochem Pharmacol. 2016 Aug 15;114:22-39. doi: 10.1016/j.bcp.2016.04.014. Epub 2016 Apr 27. Review.

PMID:
27131862
6.

A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism.

Gabl M, Holdfeldt A, Winther M, Oprea T, Bylund J, Dahlgren C, Forsman H.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1228-37. doi: 10.1016/j.bbamcr.2016.03.014. Epub 2016 Mar 18.

PMID:
26996596
7.

Development of perceived competence, tactical skills, motivation, technical skills, and speed and agility in young soccer players.

Forsman H, Gråstén A, Blomqvist M, Davids K, Liukkonen J, Konttinen N.

J Sports Sci. 2016 Jul;34(14):1311-8. doi: 10.1080/02640414.2015.1127401. Epub 2015 Dec 28.

PMID:
26708723
8.

Development and validation of the Perceived Game-Specific Soccer Competence Scale.

Forsman H, Gråstén A, Blomqvist M, Davids K, Liukkonen J, Konttinen N.

J Sports Sci. 2016 Jul;34(14):1319-27. doi: 10.1080/02640414.2015.1125518. Epub 2015 Dec 28.

PMID:
26708611
9.

IL-4 Protects the Mitochondria Against TNFα and IFNγ Induced Insult During Clearance of Infection with Citrobacter rodentium and Escherichia coli.

Maiti AK, Sharba S, Navabi N, Forsman H, Fernandez HR, Lindén SK.

Sci Rep. 2015 Oct 20;5:15434. doi: 10.1038/srep15434.

10.

Visual functioning and health-related quality of life in diabetic patients about to undergo anti-vascular endothelial growth factor treatment for sight-threatening macular edema.

Granström T, Forsman H, Leksell J, Jani S, Raghib AM, Granstam E.

J Diabetes Complications. 2015 Nov-Dec;29(8):1183-90. doi: 10.1016/j.jdiacomp.2015.07.026. Epub 2015 Aug 1.

11.

P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism.

Gabl M, Winther M, Welin A, Karlsson A, Oprea T, Bylund J, Dahlgren C, Forsman H.

Exp Cell Res. 2015 Aug 15;336(2):242-52. doi: 10.1016/j.yexcr.2015.07.014. Epub 2015 Jul 17.

PMID:
26192818
12.

A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead.

Winther M, Gabl M, Welin A, Dahlgren C, Forsman H.

FEBS Lett. 2015 Jul 8;589(15):1832-9. doi: 10.1016/j.febslet.2015.05.050. Epub 2015 Jun 9.

13.

The proteolytically stable peptidomimetic Pam-(Lys-βNSpe)6-NH2 selectively inhibits human neutrophil activation via formyl peptide receptor 2.

Skovbakke SL, Heegaard PM, Larsen CJ, Franzyk H, Forsman H, Dahlgren C.

Biochem Pharmacol. 2015 Jan 15;93(2):182-95. doi: 10.1016/j.bcp.2014.11.004. Epub 2014 Nov 14.

PMID:
25462815
14.

Structural changes of the ligand and of the receptor alters the receptor preference for neutrophil activating peptides starting with a formylmethionyl group.

Forsman H, Winther M, Gabl M, Skovbakke SL, Boulay F, Rabiet MJ, Dahlgren C.

Biochim Biophys Acta. 2015 Jan;1853(1):192-200. doi: 10.1016/j.bbamcr.2014.10.021. Epub 2014 Oct 30.

15.

CFP-10 from Mycobacterium tuberculosis selectively activates human neutrophils through a pertussis toxin-sensitive chemotactic receptor.

Welin A, Björnsdottir H, Winther M, Christenson K, Oprea T, Karlsson A, Forsman H, Dahlgren C, Bylund J.

Infect Immun. 2015 Jan;83(1):205-13. doi: 10.1128/IAI.02493-14. Epub 2014 Oct 20.

16.

A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2.

Gabl M, Winther M, Skovbakke SL, Bylund J, Dahlgren C, Forsman H.

PLoS One. 2014 Oct 10;9(10):e109516. doi: 10.1371/journal.pone.0109516. eCollection 2014.

17.

The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on arthritis.

Engdahl C, Börjesson AE, Forsman HF, Andersson A, Stubelius A, Krust A, Chambon P, Islander U, Ohlsson C, Carlsten H, Lagerquist MK.

Arthritis Res Ther. 2014 Jul 15;16(4):R150. doi: 10.1186/ar4612.

18.

Antibacterial activity of pepducins, allosterical modulators of formyl peptide receptor signaling.

Winther M, Gabl M, Oprea TI, Jönsson B, Boulay F, Bylund J, Dahlgren C, Forsman H.

Antimicrob Agents Chemother. 2014 May;58(5):2985-8. doi: 10.1128/AAC.02716-13. Epub 2014 Mar 3.

19.

A novel receptor cross-talk between the ATP receptor P2Y2 and formyl peptide receptors reactivates desensitized neutrophils to produce superoxide.

Önnheim K, Christenson K, Gabl M, Burbiel JC, Müller CE, Oprea TI, Bylund J, Dahlgren C, Forsman H.

Exp Cell Res. 2014 Apr 15;323(1):209-17. doi: 10.1016/j.yexcr.2014.01.023. Epub 2014 Feb 1.

PMID:
24491917
20.

The subcellular localization of the receptor for platelet-activating factor in neutrophils affects signaling and activation characteristics.

Andréasson E, Önnheim K, Forsman H.

Clin Dev Immunol. 2013;2013:456407. doi: 10.1155/2013/456407. Epub 2013 Aug 29.

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