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Items: 1 to 20 of 113


The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing.

Sexton JE, Desmonds T, Quick K, Taylor R, Abramowitz J, Forge A, Kros CJ, Birnbaumer L, Wood JN.

Neurosci Lett. 2016 Jan 1;610:36-42. doi: 10.1016/j.neulet.2015.10.052. Epub 2015 Oct 28.


Association of intracellular and synaptic organization in cochlear inner hair cells revealed by 3D electron microscopy.

Bullen A, West T, Moores C, Ashmore J, Fleck RA, MacLellan-Gibson K, Forge A.

J Cell Sci. 2015 Jul 15;128(14):2529-40. doi: 10.1242/jcs.170761. Epub 2015 Jun 4.


Junctions in human health and inherited disease.

Getsios S, Kelsell DP, Forge A.

Cell Tissue Res. 2015 Jun;360(3):435-8. doi: 10.1007/s00441-015-2171-2. Epub 2015 Apr 11. No abstract available.


Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing.

Taylor RR, Jagger DJ, Saeed SR, Axon P, Donnelly N, Tysome J, Moffatt D, Irving R, Monksfield P, Coulson C, Freeman SR, Lloyd SK, Forge A.

Neurobiol Aging. 2015 Jun;36(6):2068-84. doi: 10.1016/j.neurobiolaging.2015.02.013. Epub 2015 Feb 17.


Gap junctional coupling is essential for epithelial repair in the avian cochlea.

Jagger DJ, Nickel R, Forge A.

J Neurosci. 2014 Nov 26;34(48):15851-60. doi: 10.1523/JNEUROSCI.1932-14.2014.


Connexins and gap junctions in the inner ear--it's not just about K⁺ recycling.

Jagger DJ, Forge A.

Cell Tissue Res. 2015 Jun;360(3):633-44. doi: 10.1007/s00441-014-2029-z. Epub 2014 Nov 9. Review.


Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

Chen J, Ingham N, Kelly J, Jadeja S, Goulding D, Pass J, Mahajan VB, Tsang SH, Nijnik A, Jackson IJ, White JK, Forge A, Jagger D, Steel KP.

PLoS Genet. 2014 Oct 30;10(10):e1004688. doi: 10.1371/journal.pgen.1004688. eCollection 2014 Oct.


ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells.

Morozko EL, Nishio A, Ingham NJ, Chandra R, Fitzgerald T, Martelletti E, Borck G, Wilson E, Riordan GP, Wangemann P, Forge A, Steel KP, Liddle RA, Friedman TB, Belyantseva IA.

Hum Mol Genet. 2015 Feb 1;24(3):609-24. doi: 10.1093/hmg/ddu474. Epub 2014 Sep 12.


Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice.

Taylor R, Bullen A, Johnson SL, Grimm-Günter EM, Rivero F, Marcotti W, Forge A, Daudet N.

Hum Mol Genet. 2015 Jan 1;24(1):37-49. doi: 10.1093/hmg/ddu417. Epub 2014 Aug 14.


Inner ear tissue preservation by rapid freezing: improving fixation by high-pressure freezing and hybrid methods.

Bullen A, Taylor RR, Kachar B, Moores C, Fleck RA, Forge A.

Hear Res. 2014 Sep;315:49-60. doi: 10.1016/j.heares.2014.06.006. Epub 2014 Jul 10.


Cochlear implantation in the mouse via the round window: effects of array insertion.

Mistry N, Nolan LS, Saeed SR, Forge A, Taylor RR.

Hear Res. 2014 Jun;312:81-90. doi: 10.1016/j.heares.2014.03.005. Epub 2014 Mar 18.


Hearing loss in a mouse model of 22q11.2 Deletion Syndrome.

Fuchs JC, Zinnamon FA, Taylor RR, Ivins S, Scambler PJ, Forge A, Tucker AS, Linden JF.

PLoS One. 2013 Nov 14;8(11):e80104. doi: 10.1371/journal.pone.0080104. eCollection 2013.


Tricellulin deficiency affects tight junction architecture and cochlear hair cells.

Nayak G, Lee SI, Yousaf R, Edelmann SE, Trincot C, Van Itallie CM, Sinha GP, Rafeeq M, Jones SM, Belyantseva IA, Anderson JM, Forge A, Frolenkov GI, Riazuddin S.

J Clin Invest. 2013 Sep;123(9):4036-49. doi: 10.1172/JCI69031. Epub 2013 Aug 27.


Connexin30-mediated intercellular communication plays an essential role in epithelial repair in the cochlea.

Forge A, Jagger DJ, Kelly JJ, Taylor RR.

J Cell Sci. 2013 Apr 1;126(Pt 7):1703-12. doi: 10.1242/jcs.125476. Epub 2013 Feb 19.


Selective ablation of pillar and deiters' cells severely affects cochlear postnatal development and hearing in mice.

Mellado Lagarde MM, Cox BC, Fang J, Taylor R, Forge A, Zuo J.

J Neurosci. 2013 Jan 23;33(4):1564-76. doi: 10.1523/JNEUROSCI.3088-12.2013.


The enigmatic root cell - emerging roles contributing to fluid homeostasis within the cochlear outer sulcus.

Jagger DJ, Forge A.

Hear Res. 2013 Sep;303:1-11. doi: 10.1016/j.heares.2012.10.010. Epub 2012 Nov 11. Review.


Motor-driven motility of fungal nuclear pores organizes chromosomes and fosters nucleocytoplasmic transport.

Steinberg G, Schuster M, Theisen U, Kilaru S, Forge A, Martin-Urdiroz M.

J Cell Biol. 2012 Aug 6;198(3):343-55. doi: 10.1083/jcb.201201087. Epub 2012 Jul 30.


TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.

Quick K, Zhao J, Eijkelkamp N, Linley JE, Rugiero F, Cox JJ, Raouf R, Gringhuis M, Sexton JE, Abramowitz J, Taylor R, Forge A, Ashmore J, Kirkwood N, Kros CJ, Richardson GP, Freichel M, Flockerzi V, Birnbaumer L, Wood JN.

Open Biol. 2012 May;2(5):120068. doi: 10.1098/rsob.120068.


Contractility in type III cochlear fibrocytes is dependent on non-muscle myosin II and intercellular gap junctional coupling.

Kelly JJ, Forge A, Jagger DJ.

J Assoc Res Otolaryngol. 2012 Aug;13(4):473-84. doi: 10.1007/s10162-012-0322-7. Epub 2012 Apr 5.


β3-integrin is required for differentiation in OC-2 cells derived from mammalian embryonic inner ear.

Brunetta I, Casalotti SO, Hart IR, Forge A, Reynolds LE.

BMC Cell Biol. 2012 Mar 17;13:5. doi: 10.1186/1471-2121-13-5.

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