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Results: 1 to 20 of 225


In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors.

Barbieri F, Thellung S, Ratto A, Carra E, Marini V, Fucile C, Bajetto A, Pattarozzi A, Würth R, Gatti M, Campanella C, Vito G, Mattioli F, Pagano A, Daga A, Ferrari A, Florio T.

BMC Cancer. 2015 Apr 7;15:228. doi: 10.1186/s12885-015-1235-8.


Ruta graveolens L. Induces Death of Glioblastoma Cells and Neural Progenitors, but Not of Neurons, via ERK 1/2 and AKT Activation.

Gentile MT, Ciniglia C, Reccia MG, Volpicelli F, Gatti M, Thellung S, Florio T, Melone MA, Colucci-D'Amato L.

PLoS One. 2015 Mar 18;10(3):e0118864. doi: 10.1371/journal.pone.0118864. eCollection 2015.


Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets.

Peretti M, Angelini M, Savalli N, Florio T, Yuspa SH, Mazzanti M.

Biochim Biophys Acta. 2014 Dec 26. pii: S0005-2736(14)00440-4. doi: 10.1016/j.bbamem.2014.12.012. [Epub ahead of print] Review.


PPARβ/δ and γ in a rat model of Parkinson's disease: possible involvement in PD symptoms.

Falcone R, Florio TM, Di Giacomo E, Benedetti E, Cristiano L, Antonosante A, Fidoamore A, Massimi M, Alecci M, Ippoliti R, Giordano A, Cimini A.

J Cell Biochem. 2015 May;116(5):844-55. doi: 10.1002/jcb.25041.


Emerging Targets in Pituitary Adenomas: Role of the CXCL12/CXCR4-R7 System.

Barbieri F, Thellung S, Würth R, Gatto F, Corsaro A, Villa V, Nizzari M, Albertelli M, Ferone D, Florio T.

Int J Endocrinol. 2014;2014:753524. doi: 10.1155/2014/753524. Epub 2014 Nov 17. Review.


Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells.

Villa V, Thellung S, Corsaro A, Novelli F, Tasso B, Colucci-D'Amato L, Gatta E, Tonelli M, Florio T.

Mol Neurobiol. 2014 Nov 18. [Epub ahead of print]


Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current.

Gritti M, Würth R, Angelini M, Barbieri F, Peretti M, Pizzi E, Pattarozzi A, Carra E, Sirito R, Daga A, Curmi PM, Mazzanti M, Florio T.

Oncotarget. 2014 Nov 30;5(22):11252-68.


Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA.

Costa D, Gigoni A, Würth R, Cancedda R, Florio T, Pagano A.

Cancer Cell Int. 2014 Jul 2;14:59. doi: 10.1186/1475-2867-14-59. eCollection 2014.


Pasireotide and octreotide antiproliferative effects and sst2 trafficking in human pancreatic neuroendocrine tumor cultures.

Mohamed A, Blanchard MP, Albertelli M, Barbieri F, Brue T, Niccoli P, Delpero JR, Monges G, Garcia S, Ferone D, Florio T, Enjalbert A, Moutardier V, Schonbrunn A, Gerard C, Barlier A, Saveanu A.

Endocr Relat Cancer. 2014 Oct;21(5):691-704. doi: 10.1530/ERC-14-0086. Epub 2014 Jul 10.


Ambulatory mental health data demonstrates the high needs of people with an intellectual disability: results from the New South Wales intellectual disability and mental health data linkage project.

Howlett S, Florio T, Xu H, Trollor J.

Aust N Z J Psychiatry. 2015 Feb;49(2):137-44. doi: 10.1177/0004867414536933. Epub 2014 Jun 9.


CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment.

Würth R, Bajetto A, Harrison JK, Barbieri F, Florio T.

Front Cell Neurosci. 2014 May 28;8:144. doi: 10.3389/fncel.2014.00144. eCollection 2014. Review.


Adiponectin as novel regulator of cell proliferation in human glioblastoma.

Porcile C, Di Zazzo E, Monaco ML, D'Angelo G, Passarella D, Russo C, Di Costanzo A, Pattarozzi A, Gatti M, Bajetto A, Zona G, Barbieri F, Oriani G, Moncharmont B, Florio T, Daniele A.

J Cell Physiol. 2014 Oct;229(10):1444-54. doi: 10.1002/jcp.24582.


New molecules and old drugs as emerging approaches to selectively target human glioblastoma cancer stem cells.

Würth R, Barbieri F, Florio T.

Biomed Res Int. 2014;2014:126586. doi: 10.1155/2014/126586. Epub 2014 Jan 2. Review.


Neuroendocrine tumors: insights into innovative therapeutic options and rational development of targeted therapies.

Barbieri F, Albertelli M, Grillo F, Mohamed A, Saveanu A, Barlier A, Ferone D, Florio T.

Drug Discov Today. 2014 Apr;19(4):458-68. doi: 10.1016/j.drudis.2013.10.015. Epub 2013 Oct 27. Review.


Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity.

Gatti M, Pattarozzi A, Bajetto A, Würth R, Daga A, Fiaschi P, Zona G, Florio T, Barbieri F.

Toxicology. 2013 Dec 15;314(2-3):209-20. doi: 10.1016/j.tox.2013.10.003. Epub 2013 Oct 21.


Minimalist hybrid ligand/receptor-based pharmacophore model for CXCR4 applied to a small-library of marine natural products led to the identification of phidianidine a as a new CXCR4 ligand exhibiting antagonist activity.

Vitale RM, Gatti M, Carbone M, Barbieri F, Felicità V, Gavagnin M, Florio T, Amodeo P.

ACS Chem Biol. 2013 Dec 20;8(12):2762-70. doi: 10.1021/cb400521b. Epub 2013 Oct 30.


Switching ability of over trained movements in a Parkinson's disease rat model.

Florio TM, Confalone G, Sciarra A, Sotgiu A, Alecci M.

Behav Brain Res. 2013 Aug 1;250:326-33. doi: 10.1016/j.bbr.2013.05.020. Epub 2013 May 21.


Differential role of EGF and BFGF in human GBM-TIC proliferation: relationship to EGFR-tyrosine kinase inhibitor sensibility.

Bajetto A, Porcile C, Pattarozzi A, Scotti L, Aceto A, Daga A, Barbieri F, Florio T.

J Biol Regul Homeost Agents. 2013 Jan-Mar;27(1):143-54.


A novel snRNA-like transcript affects amyloidogenesis and cell cycle progression through perturbation of Fe65L1 (APBB2) alternative splicing.

Penna I, Vassallo I, Nizzari M, Russo D, Costa D, Menichini P, Poggi A, Russo C, Dieci G, Florio T, Cancedda R, Pagano A.

Biochim Biophys Acta. 2013 Jun;1833(6):1511-26. doi: 10.1016/j.bbamcr.2013.02.020. Epub 2013 Feb 26.


Peptide receptor targeting in cancer: the somatostatin paradigm.

Barbieri F, Bajetto A, Pattarozzi A, Gatti M, Würth R, Thellung S, Corsaro A, Villa V, Nizzari M, Florio T.

Int J Pept. 2013;2013:926295. doi: 10.1155/2013/926295. Epub 2013 Feb 7.

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