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Results: 1 to 20 of 142

1.

Investigation of potential mechanisms of sex differences in quinidine-induced torsade de pointes risk.

Vicente J, Simlund J, Johannesen L, Sundh F, Florian J, Ugander M, Wagner GS, Woosley RL, Strauss DG.

J Electrocardiol. 2015 Mar 12. pii: S0022-0736(15)00070-9. doi: 10.1016/j.jelectrocard.2015.03.011. [Epub ahead of print]

PMID:
25796102
2.

Trial geography, pharmacogenetics, and global drug development.

Schuck R, Florian J, Charlab R, Pacanowski M.

Clin Pharmacol Ther. 2015 Mar;97(3):218-20. doi: 10.1002/cpt.27. Epub 2014 Dec 15.

PMID:
25669642
3.

FDA perspective on sofosbuvir therapy for patients with chronic hepatitis C virus genotype 1 infection who did not respond to treatment with pegylated interferon and ribavirin.

Mishra P, Florian J, Qi K, Zeng W, Naeger LK, Donaldson E, Connelly S, O'Rear J, Price D, Murray J, Birnkrant D.

Gastroenterology. 2014 Dec;147(6):1196-200. doi: 10.1053/j.gastro.2014.10.027. Epub 2014 Oct 27. No abstract available.

PMID:
25449024
4.

Preventive treatments for breast cancer: recent developments.

Alés-Martínez JE, Ruiz A, Chacón JI, Lluch Hernández A, Ramos M, Córdoba O, Aguirre E, Barnadas A, Jara C, González S, Plazaola A, Florián J, Andrés R, Sánchez Rovira P, Frau A.

Clin Transl Oncol. 2015 Apr;17(4):257-63. doi: 10.1007/s12094-014-1250-2. Epub 2014 Dec 2.

5.

Flexible docking-based molecular dynamics/steered molecular dynamics calculations of protein-protein contacts in a complex of cytochrome P450 1A2 with cytochrome b5.

Jeřábek P, Florián J, Stiborová M, Martínek V.

Biochemistry. 2014 Oct 28;53(42):6695-705. doi: 10.1021/bi500814t. Epub 2014 Oct 14.

PMID:
25313797
6.

Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil.

Johannesen L, Vicente J, Mason JW, Sanabria C, Waite-Labott K, Hong M, Guo P, Lin J, Sørensen JS, Galeotti L, Florian J, Ugander M, Stockbridge N, Strauss DG.

Clin Pharmacol Ther. 2014 Nov;96(5):549-58. doi: 10.1038/clpt.2014.155. Epub 2014 Jul 23.

PMID:
25054430
7.

Quantum mechanical analysis of nonenzymatic nucleotidyl transfer reactions: kinetic and thermodynamic effects of β-γ bridging groups of dNTP substrates.

Zhang Z, Eloge J, Florián J.

Biochemistry. 2014 Jul 1;53(25):4180-91. doi: 10.1021/bi5003713. Epub 2014 Jun 17.

PMID:
24901652
8.

Novel electrodes for underwater ECG monitoring.

Reyes BA, Posada-Quintero HF, Bales JR, Clement AL, Pins GD, Swiston A, Riistama J, Florian JP, Shykoff B, Qin M, Chon KH.

IEEE Trans Biomed Eng. 2014 Jun;61(6):1863-76. doi: 10.1109/TBME.2014.2309293.

PMID:
24845297
9.

U.S. Food and drug administration approval: obinutuzumab in combination with chlorambucil for the treatment of previously untreated chronic lymphocytic leukemia.

Lee HZ, Miller BW, Kwitkowski VE, Ricci S, DelValle P, Saber H, Grillo J, Bullock J, Florian J, Mehrotra N, Ko CW, Nie L, Shapiro M, Tolnay M, Kane RC, Kaminskas E, Justice R, Farrell AT, Pazdur R.

Clin Cancer Res. 2014 Aug 1;20(15):3902-7. doi: 10.1158/1078-0432.CCR-14-0516. Epub 2014 May 13.

PMID:
24824310
10.

Metal ion complexes of N,N'-bis(2-pyridylmethyl)-1,3-diaminopropane-N,N'-diacetic acid, H2bppd.

Kissel DS, Florián J, McLauchlan CC, Herlinger AW.

Inorg Chem. 2014 Apr 7;53(7):3404-16. doi: 10.1021/ic402810e. Epub 2014 Mar 21.

PMID:
24649926
11.

The incidence and outcomes of acute coronary syndromes in a central European country: results of the CZECH-2 registry.

Tousek P, Tousek F, Horak D, Cervinka P, Rokyta R, Pesl L, Jarkovsky J, Widimsky P; CZECH-2 Investigators.

Int J Cardiol. 2014 May 1;173(2):204-8. doi: 10.1016/j.ijcard.2014.02.013. Epub 2014 Feb 22.

12.

FDA bridging analyses confirmed in clinical trial.

Mishra P, Florian J, Murray J.

Hepatology. 2014 Dec;60(6):2134. doi: 10.1002/hep.27107. Epub 2014 Sep 25. No abstract available.

PMID:
24591059
13.

Improving the assessment of heart toxicity for all new drugs through translational regulatory science.

Johannesen L, Vicente J, Gray RA, Galeotti L, Loring Z, Garnett CE, Florian J, Ugander M, Stockbridge N, Strauss DG.

Clin Pharmacol Ther. 2014 May;95(5):501-8. doi: 10.1038/clpt.2013.238. Epub 2013 Dec 12.

PMID:
24336137
14.

Edoxaban versus warfarin in patients with atrial fibrillation.

Giugliano RP, Ruff CT, Braunwald E, Murphy SA, Wiviott SD, Halperin JL, Waldo AL, Ezekowitz MD, Weitz JI, Špinar J, Ruzyllo W, Ruda M, Koretsune Y, Betcher J, Shi M, Grip LT, Patel SP, Patel I, Hanyok JJ, Mercuri M, Antman EM; ENGAGE AF-TIMI 48 Investigators.

N Engl J Med. 2013 Nov 28;369(22):2093-104. doi: 10.1056/NEJMoa1310907. Epub 2013 Nov 19.

15.

Does an increase in serum creatinine always reflect renal injury? The case of Stribild®

Arya V, Florian J, Marcus KA, Reynolds KS, Lewis LL, Sherwat AI.

J Clin Pharmacol. 2013 Nov 8. doi: 10.1002/jcph.223. [Epub ahead of print]

PMID:
24214102
16.

Cardiovascular and autonomic responses to physiological stressors before and after six hours of water immersion.

Florian JP, Simmons EE, Chon KH, Faes L, Shykoff BE.

J Appl Physiol (1985). 2013 Nov 1;115(9):1275-89. doi: 10.1152/japplphysiol.00466.2013. Epub 2013 Aug 15.

17.

Impact of pulmonary rehabilitation on quality of life and functional capacity in patients on waiting lists for lung transplantation.

Florian J, Rubin A, Mattiello R, Fontoura FF, Camargo Jde J, Teixeira PJ.

J Bras Pneumol. 2013 May-Jun;39(3):349-56. doi: 10.1590/S1806-37132013000300012. English, Portuguese.

18.

Are women more susceptible than men to drug-induced QT prolongation? Concentration-QTc modelling in a phase 1 study with oral rac-sotalol.

Darpo B, Karnad DR, Badilini F, Florian J, Garnett CE, Kothari S, Panicker GK, Sarapa N.

Br J Clin Pharmacol. 2014 Mar;77(3):522-31. doi: 10.1111/bcp.12201.

19.

Measuring postural-related changes of spontaneous baroreflex sensitivity after repeated long-duration diving: frequency domain approaches.

Faes L, Masè M, Nollo G, Chon KH, Florian JP.

Auton Neurosci. 2013 Nov;178(1-2):96-102. doi: 10.1016/j.autneu.2013.03.006. Epub 2013 Apr 13.

PMID:
23587978
20.

Applicability of the London Chest Activity of Daily Living scale in patients on the waiting list for lung transplantation.

Muller JP, Gonçalves PA, Fontoura FF, Mattiello R, Florian J.

J Bras Pneumol. 2013 Jan-Feb;39(1):92-7. English, Portuguese.

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