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Results: 1 to 20 of 1156

1.

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis.

Pan W, Zhu S, Dai D, Liu Z, Li D, Li B, Gagliani N, Zheng Y, Tang Y, Weirauch MT, Chen X, Zhu W, Wang Y, Chen B, Qian Y, Chen Y, Fang J, Herbst R, Richman L, Jallal B, Harley JB, Flavell RA, Yao Y, Shen N.

Nat Commun. 2015 May 12;6:7096. doi: 10.1038/ncomms8096.

PMID:
25963922
2.

Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation.

Gagliani N, Vesely MC, Iseppon A, Brockmann L, Xu H, Palm NW, de Zoete MR, Licona-Limón P, Paiva RS, Ching T, Weaver C, Zi X, Pan X, Fan R, Garmire LX, Cotton MJ, Drier Y, Bernstein B, Geginat J, Stockinger B, Esplugues E, Huber S, Flavell RA.

Nature. 2015 Apr 29. doi: 10.1038/nature14452. [Epub ahead of print]

PMID:
25924064
3.

Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAP Kinase Phosphatase 5.

Zhang Y, Nguyen T, Tang P, Kennedy NJ, Jiao H, Zhang M, Reynolds JM, Jaeschke A, Martin-Orozco N, Chung Y, He WM, Wang C, Jia W, Ge B, Davis RJ, Flavell RA, Dong C.

J Biol Chem. 2015 Apr 28. pii: jbc.M115.660969. [Epub ahead of print]

4.

Retraction for Theivanthiran et al., NOD2 Signaling Contributes to Host Defense in the Lungs against Escherichia coli Infection.

Theivanthiran B, Batra S, Balamayooran G, Cai S, Kobayashi K, Flavell RA, Jeyaseelan S.

Infect Immun. 2015 May;83(5):2199. doi: 10.1128/IAI.00200-15. No abstract available.

5.

Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes.

Willinger T, Staron M, Ferguson SM, De Camilli P, Flavell RA.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4423-8. doi: 10.1073/pnas.1504279112. Epub 2015 Mar 23.

PMID:
25831514
6.

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome.

Macia L, Tan J, Vieira AT, Leach K, Stanley D, Luong S, Maruya M, Ian McKenzie C, Hijikata A, Wong C, Binge L, Thorburn AN, Chevalier N, Ang C, Marino E, Robert R, Offermanns S, Teixeira MM, Moore RJ, Flavell RA, Fagarasan S, Mackay CR.

Nat Commun. 2015 Apr 1;6:6734. doi: 10.1038/ncomms7734.

PMID:
25828455
7.

MAPK Phosphatase 5 Expression Induced by Influenza and Other RNA Virus Infection Negatively Regulates IRF3 Activation and Type I Interferon Response.

James SJ, Jiao H, Teh HY, Takahashi H, Png CW, Phoon MC, Suzuki Y, Sawasaki T, Xiao H, Chow VT, Yamamoto N, Reynolds JM, Flavell RA, Dong C, Zhang Y.

Cell Rep. 2015 Mar 11. pii: S2211-1247(15)00176-X. doi: 10.1016/j.celrep.2015.02.030. [Epub ahead of print]

PMID:
25772359
Free Article
8.

DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis.

Png CW, Weerasooriya M, Guo J, James SJ, Poh HM, Osato M, Flavell RA, Dong C, Yang H, Zhang Y.

Oncogene. 2015 Mar 16. doi: 10.1038/onc.2015.74. [Epub ahead of print]

PMID:
25772234
9.

Myosin VI regulates gene pairing and transcriptional pause release in T cells.

Zorca CE, Kim LK, Kim YJ, Krause MR, Zenklusen D, Spilianakis CG, Flavell RA.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1587-93. doi: 10.1073/pnas.1502461112. Epub 2015 Mar 13.

PMID:
25770220
10.

Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression.

Stratigi K, Kapsetaki M, Aivaliotis M, Town T, Flavell RA, Spilianakis CG.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1577-86. doi: 10.1073/pnas.1502182112. Epub 2015 Mar 13.

11.

Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration.

Krishnaswamy JK, Singh A, Gowthaman U, Wu R, Gorrepati P, Sales Nascimento M, Gallman A, Liu D, Rhebergen AM, Calabro S, Xu L, Ranney P, Srivastava A, Ranson M, Gorham JD, McCaw Z, Kleeberger SR, Heinz LX, Müller AC, Bennett KL, Superti-Furga G, Henao-Mejia J, Sutterwala FS, Williams A, Flavell RA, Eisenbarth SC.

Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3056-61. doi: 10.1073/pnas.1501554112. Epub 2015 Feb 23.

PMID:
25713392
12.

IRAK-M promotes alternative macrophage activation and fibroproliferation in bleomycin-induced lung injury.

Ballinger MN, Newstead MW, Zeng X, Bhan U, Mo XM, Kunkel SL, Moore BB, Flavell R, Christman JW, Standiford TJ.

J Immunol. 2015 Feb 15;194(4):1894-904. doi: 10.4049/jimmunol.1402377. Epub 2015 Jan 16.

PMID:
25595781
13.

Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M.

Miyata M, Lee JY, Susuki-Miyata S, Wang WY, Xu H, Kai H, Kobayashi KS, Flavell RA, Li JD.

Nat Commun. 2015 Jan 14;6:6062. doi: 10.1038/ncomms7062.

14.

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.

Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, Deeks SG, Strowig T, Kumar P, Siliciano JD, Salzberg SL, Flavell RA, Shan L, Siliciano RF.

Nature. 2015 Jan 15;517(7534):381-5. doi: 10.1038/nature14053. Epub 2015 Jan 7.

PMID:
25561180
15.

Resemble and Inhibit: when RLR meets TGF-β.

Zhu S, Li HB, Flavell RA.

Mol Cell. 2014 Dec 18;56(6):719-20. doi: 10.1016/j.molcel.2014.12.010.

PMID:
25526529
16.

Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.

Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA.

Cell. 2014 Dec 18;159(7):1563-77. doi: 10.1016/j.cell.2014.11.037.

PMID:
25525875
17.

Producing GM-CSF: a unique T helper subset?

Herndler-Brandstetter D, Flavell RA.

Cell Res. 2014 Dec;24(12):1379-80. doi: 10.1038/cr.2014.155. Epub 2014 Nov 21.

PMID:
25412663
18.

FLUshing in the bathroom.

Amezcua C, Gagliani N, Flavell R.

J Exp Med. 2014 Nov 17;211(12):2328-9. doi: 10.1084/jem.21112insight4. No abstract available.

19.

Antivirulence properties of an antifreeze protein.

Heisig M, Abraham NM, Liu L, Neelakanta G, Mattessich S, Sultana H, Shang Z, Ansari JM, Killiam C, Walker W, Cooley L, Flavell RA, Agaisse H, Fikrig E.

Cell Rep. 2014 Oct 23;9(2):417-24. doi: 10.1016/j.celrep.2014.09.034. Epub 2014 Oct 16. Erratum in: Cell Rep. 2014 Dec 24;9(6):2344.

20.

Inflammasomes.

de Zoete MR, Palm NW, Zhu S, Flavell RA.

Cold Spring Harb Perspect Biol. 2014 Oct 16;6(12):a016287. doi: 10.1101/cshperspect.a016287.

PMID:
25324215
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