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Items: 13


Pharmacokinetics of Anti-VEGF Agent Aflibercept in Cancer Predicted by Data-Driven, Molecular-Detailed Model.

Finley SD, Angelikopoulos P, Koumoutsakos P, Popel AS.

CPT Pharmacometrics Syst Pharmacol. 2015 Nov;4(11):641-9. doi: 10.1002/psp4.12040. Epub 2015 Oct 9.


Computational systems biology approaches to anti-angiogenic cancer therapeutics.

Finley SD, Chu LH, Popel AS.

Drug Discov Today. 2015 Feb;20(2):187-97. doi: 10.1016/j.drudis.2014.09.026. Epub 2014 Oct 5. Review.


A systems biology view of blood vessel growth and remodelling.

Logsdon EA, Finley SD, Popel AS, Mac Gabhann F.

J Cell Mol Med. 2014 Aug;18(8):1491-508. doi: 10.1111/jcmm.12164. Epub 2013 Nov 17. Review.


Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice.

Finley SD, Dhar M, Popel AS.

Front Oncol. 2013 Jul 30;3:196. doi: 10.3389/fonc.2013.00196. eCollection 2013.


Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions.

Finley SD, Popel AS.

J Natl Cancer Inst. 2013 Jun 5;105(11):802-11. doi: 10.1093/jnci/djt093. Epub 2013 May 13.


Predicting the effects of anti-angiogenic agents targeting specific VEGF isoforms.

Finley SD, Popel AS.

AAPS J. 2012 Sep;14(3):500-9. doi: 10.1208/s12248-012-9363-4. Epub 2012 May 1.


Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies.

Finley SD, Engel-Stefanini MO, Imoukhuede PI, Popel AS.

BMC Syst Biol. 2011 Nov 21;5:193. doi: 10.1186/1752-0509-5-193.


A two-compartment model of VEGF distribution in the mouse.

Yen P, Finley SD, Engel-Stefanini MO, Popel AS.

PLoS One. 2011;6(11):e27514. doi: 10.1371/journal.pone.0027514. Epub 2011 Nov 8.


Timescale analysis of rule-based biochemical reaction networks.

Klinke DJ 2nd, Finley SD.

Biotechnol Prog. 2012 Jan-Feb;28(1):33-44. doi: 10.1002/btpr.704. Epub 2011 Sep 26.


Inferring relevant control mechanisms for interleukin-12 signaling in naïve CD4+ T cells.

Finley SD, Gupta D, Cheng N, Klinke DJ 2nd.

Immunol Cell Biol. 2011 Jan;89(1):100-10. doi: 10.1038/icb.2010.69. Epub 2010 May 18.


In silico feasibility of novel biodegradation pathways for 1,2,4-trichlorobenzene.

Finley SD, Broadbelt LJ, Hatzimanikatis V.

BMC Syst Biol. 2010 Feb 2;4:7. doi: 10.1186/1752-0509-4-7.


Computational framework for predictive biodegradation.

Finley SD, Broadbelt LJ, Hatzimanikatis V.

Biotechnol Bioeng. 2009 Dec 15;104(6):1086-97. doi: 10.1002/bit.22489.


Thermodynamic analysis of biodegradation pathways.

Finley SD, Broadbelt LJ, Hatzimanikatis V.

Biotechnol Bioeng. 2009 Jun 15;103(3):532-41. doi: 10.1002/bit.22285.

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