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Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter-determining Validation Requirements.

Humby F, Kelly S, Bugatti S, Manzo A, Filer A, Mahto A, Fonseca JE, Lauwerys B, D'Agostino MA, Naredo E, Lories R, Montecucco C, Tak PP, Fitzgerald O, Smith MD, Veale DJ, Choy EH, Strand V, Pitzalis C.

J Rheumatol. 2015 Jun 1. pii: jrheum.141199. [Epub ahead of print]


Ultrasound-guided synovial biopsy: a systematic review according to the OMERACT filter and recommendations for minimal reporting standards in clinical studies.

Lazarou I, D'Agostino MA, Naredo E, Humby F, Filer A, Kelly SG.

Rheumatology (Oxford). 2015 May 28. pii: kev128. [Epub ahead of print]


Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis.

Nanus DE, Filer AD, Yeo L, Scheel-Toellner D, Hardy R, Lavery GG, Stewart PM, Buckley CD, Tomlinson JW, Cooper MS, Raza K.

Arthritis Res Ther. 2015 May 14;17(1):121. doi: 10.1186/s13075-015-0633-2.


Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis.

Reynolds G, Gibbon JR, Pratt AG, Wood MJ, Coady D, Raftery G, Lorenzi AR, Gray A, Filer A, Buckley CD, Haniffa MA, Isaacs JD, Hilkens CM.

Ann Rheum Dis. 2015 Apr 28. pii: annrheumdis-2014-206578. doi: 10.1136/annrheumdis-2014-206578. [Epub ahead of print]


Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.

Chimen M, McGettrick HM, Apta B, Kuravi SJ, Yates CM, Kennedy A, Odedra A, Alassiri M, Harrison M, Martin A, Barone F, Nayar S, Hitchcock JR, Cunningham AF, Raza K, Filer A, Copland DA, Dick AD, Robinson J, Kalia N, Walker LS, Buckley CD, Nash GB, Narendran P, Rainger GE.

Nat Med. 2015 May;21(5):467-75. doi: 10.1038/nm.3842. Epub 2015 Apr 20.


Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis.

Yeo L, Adlard N, Biehl M, Juarez M, Smallie T, Snow M, Buckley CD, Raza K, Filer A, Scheel-Toellner D.

Ann Rheum Dis. 2015 Apr 9. pii: annrheumdis-2014-206921. doi: 10.1136/annrheumdis-2014-206921. [Epub ahead of print]


Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways.

Filer A, Antczak P, Parsonage GN, Legault HM, O'Toole M, Pearson MJ, Thomas AM, Scheel-Toellner D, Raza K, Buckley CD, Falciani F.

PLoS One. 2015 Mar 25;10(3):e0120917. doi: 10.1371/journal.pone.0120917. eCollection 2015.


Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health.

Ahmed U, Anwar A, Savage RS, Costa ML, Mackay N, Filer A, Raza K, Watts RA, Winyard PG, Tarr J, Haigh RC, Thornalley PJ, Rabbani N.

Sci Rep. 2015 Mar 19;5:9259. doi: 10.1038/srep09259.


The OMERACT Ultrasound Working Group 10 Years On: Update at OMERACT 12.

Bruyn GA, Naredo E, Iagnocco A, Balint PV, Backhaus M, Gandjbakhch F, Gutierrez M, Filer A, Finzel S, Ikeda K, Kaeley GS, Magni Manzoni S, Ohrndorf S, Pineda C, Richards B, Roth J, Schmidt WA, Terslev L, D'Agostino MA; OMERACT Ultrasound Task Force.

J Rheumatol. 2015 Mar 15. pii: jrheum.141462. [Epub ahead of print]


The therapeutic window of opportunity in rheumatoid arthritis: does it ever close?

Raza K, Filer A.

Ann Rheum Dis. 2015 May;74(5):793-4. doi: 10.1136/annrheumdis-2014-206993. Epub 2015 Mar 10. No abstract available.


The role of the synovial fibroblast in rheumatoid arthritis pathogenesis.

Turner JD, Filer A.

Curr Opin Rheumatol. 2015 Mar;27(2):175-82. doi: 10.1097/BOR.0000000000000148.


Stroma: fertile soil for inflammation.

Patel R, Filer A, Barone F, Buckley CD.

Best Pract Res Clin Rheumatol. 2014 Aug;28(4):565-76. doi: 10.1016/j.berh.2014.10.022. Epub 2014 Oct 30. Review.


Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice.

Misharin AV, Cuda CM, Saber R, Turner JD, Gierut AK, Haines GK 3rd, Berdnikovs S, Filer A, Clark AR, Buckley CD, Mutlu GM, Budinger GR, Perlman H.

Cell Rep. 2014 Oct 23;9(2):591-604. doi: 10.1016/j.celrep.2014.09.032. Epub 2014 Oct 16.


Diagnostic outcomes associated with ankle synovitis in early inflammatory arthritis: a cohort study.

Abhishek A, de Pablo P, Cader MZ, Buckley CD, Raza K, Filer A.

Clin Exp Rheumatol. 2014 Jul-Aug;32(4):533-8. Epub 2014 Jul 1.


Two and three dimensional network polymers for electrocatalysis.

Filer A, Choi HJ, Seo JM, Baek JB.

Phys Chem Chem Phys. 2014 Jun 21;16(23):11150-61. doi: 10.1039/c4cp01246a. Epub 2014 May 8.


Expression of FcRL4 defines a pro-inflammatory, RANKL-producing B cell subset in rheumatoid arthritis.

Yeo L, Lom H, Juarez M, Snow M, Buckley CD, Filer A, Raza K, Scheel-Toellner D.

Ann Rheum Dis. 2015 May;74(5):928-35. doi: 10.1136/annrheumdis-2013-204116. Epub 2014 Jan 15.


TNFα regulates cortisol metabolism in vivo in patients with inflammatory arthritis.

Nanus DE, Filer AD, Hughes B, Fisher BA, Taylor PC, Stewart PM, Buckley CD, McInnes I, Cooper MS, Raza K.

Ann Rheum Dis. 2015 Feb;74(2):464-9. doi: 10.1136/annrheumdis-2013-203926. Epub 2014 Jan 2.


Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients.

Kelly S, Humby F, Filer A, Ng N, Di Cicco M, Hands RE, Rocher V, Bombardieri M, D'Agostino MA, McInnes IB, Buckley CD, Taylor PC, Pitzalis C.

Ann Rheum Dis. 2015 Mar;74(3):611-7. doi: 10.1136/annrheumdis-2013-204603. Epub 2013 Dec 13.


Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis.

Filková M, Aradi B, Senolt L, Ospelt C, Vettori S, Mann H, Filer A, Raza K, Buckley CD, Snow M, Vencovský J, Pavelka K, Michel BA, Gay RE, Gay S, Jüngel A.

Ann Rheum Dis. 2014 Oct;73(10):1898-904. doi: 10.1136/annrheumdis-2012-202815. Epub 2013 Jul 29.


Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.

Cobb JE, Plant D, Flynn E, Tadjeddine M, Dieudé P, Cornélis F, Ärlestig L, Dahlqvist SR, Goulielmos G, Boumpas DT, Sidiropoulos P, Krintel SB, Ørnbjerg LM, Hetland ML, Klareskog L, Haeupl T, Filer A, Buckley CD, Raza K, Witte T, Schmidt RE, FitzGerald O, Veale D, Eyre S, Worthington J.

PLoS One. 2013 Jun 20;8(6):e66456. doi: 10.1371/journal.pone.0066456. Print 2013.

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