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Results: 1 to 20 of 164

1.

Systemic Metabolomic Changes in Blood Samples of Lung Cancer Patients Identified by Gas Chromatography Time-of-Flight Mass Spectrometry.

Miyamoto S, Taylor SL, Barupal DK, Taguchi A, Wohlgemuth G, Wikoff WR, Yoneda KY, Gandara DR, Hanash SM, Kim K, Fiehn O.

Metabolites. 2015 Apr 9;5(2):192-210. doi: 10.3390/metabo5020192.

2.

Systemic Alterations in the Metabolome of Diabetic NOD Mice Delineate Increased Oxidative Stress Accompanied by Reduced Inflammation and Hypertriglyceridemia.

Fahrmann J, Grapov D, Yang J, Hammock B, Fiehn O, Bell GI, Hara M.

Am J Physiol Endocrinol Metab. 2015 Apr 7:ajpendo.00019.2015. doi: 10.1152/ajpendo.00019.2015. [Epub ahead of print]

PMID:
25852003
3.

MetaMapR: pathway independent metabolomic network analysis incorporating unknowns.

Grapov D, Wanichthanarak K, Fiehn O.

Bioinformatics. 2015 Apr 5. pii: btv194. [Epub ahead of print]

PMID:
25847005
4.

Whey protein supplementation does not alter plasma branched-chained amino Acid profiles but results in unique metabolomics patterns in obese women enrolled in an 8-week weight loss trial.

Piccolo BD, Comerford KB, Karakas SE, Knotts TA, Fiehn O, Adams SH.

J Nutr. 2015 Apr;145(4):691-700. doi: 10.3945/jn.114.203943. Epub 2015 Feb 4.

PMID:
25833773
5.

Habitual Physical Activity and Plasma Metabolomic Patterns Distinguish Individuals with Low vs. High Weight Loss during Controlled Energy Restriction.

Piccolo BD, Keim NL, Fiehn O, Adams SH, Van Loan MD, Newman JW.

J Nutr. 2015 Apr;145(4):681-90. doi: 10.3945/jn.114.201574. Epub 2015 Jan 28.

PMID:
25833772
6.

Associations of Trimethylamine N-Oxide With Nutritional and Inflammatory Biomarkers and Cardiovascular Outcomes in Patients New to Dialysis.

Kaysen GA, Johansen KL, Chertow GM, Dalrymple LS, Kornak J, Grimes B, Dwyer T, Chassy AW, Fiehn O.

J Ren Nutr. 2015 Mar 19. pii: S1051-2276(15)00065-5. doi: 10.1053/j.jrn.2015.02.006. [Epub ahead of print]

PMID:
25802017
7.

Diabetes Associated Metabolomic Perturbations in NOD Mice.

Grapov D, Fahrmann J, Hwang J, Poudel A, Jo J, Periwal V, Fiehn O, Hara M.

Metabolomics. 2015 Apr;11(2):425-437.

PMID:
25755629
8.

Patterns of metabolite changes identified from large-scale gene perturbations in Arabidopsis using a genome-scale metabolic network.

Kim T, Dreher K, Nilo-Poyanco R, Lee I, Fiehn O, Lange BM, Nikolau BJ, Sumner L, Welti R, Wurtele ES, Rhee SY.

Plant Physiol. 2015 Apr;167(4):1685-98. doi: 10.1104/pp.114.252361. Epub 2015 Feb 10.

9.

Metabolomic Markers of Altered Nucleotide Metabolism in Early Stage Adenocarcinoma.

Wikoff W, Grapov D, Fahrmann J, DeFelice B, Rom W, Pass H, Kim K, Nguyen U, Taylor SL, Kelly K, Fiehn O, Miyamoto S.

Cancer Prev Res (Phila). 2015 Feb 5. pii: canprevres.0329.2014. [Epub ahead of print]

PMID:
25657018
10.

Efficiency of short, small-diameter columns for reversed-phase liquid chromatography under practical operating conditions.

Ma Y, Chassy AW, Miyazaki S, Motokawa M, Morisato K, Uzu H, Ohira M, Furuno M, Nakanishi K, Minakuchi H, Mriziq K, Farkas T, Fiehn O, Tanaka N.

J Chromatogr A. 2015 Feb 27;1383:47-57. doi: 10.1016/j.chroma.2015.01.014. Epub 2015 Jan 14.

PMID:
25648581
11.

Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis.

Armstrong AW, Wu J, Johnson MA, Grapov D, Azizi B, Dhillon J, Fiehn O.

F1000Res. 2014 Oct 21;3:248. doi: 10.12688/f1000research.4709.1. eCollection 2014.

12.

Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics.

Tay-Sontheimer J, Shireman LM, Beyer RP, Senn T, Witten D, Pearce RE, Gaedigk A, Gana Fomban CL, Lutz JD, Isoherranen N, Thummel KE, Fiehn O, Leeder JS, Lin YS.

Pharmacogenomics. 2014 Dec;15(16):1947-62. doi: 10.2217/pgs.14.155.

PMID:
25521354
13.

High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy.

Snowden SG, Grapov D, Settergren M, D'Alexandri FL, Haeggström JZ, Fiehn O, Hyötyläinen T, Pedersen TL, Newman JW, Orešič M, Pernow J, Wheelock CE.

Circ Cardiovasc Genet. 2014 Dec;7(6):955-64. doi: 10.1161/CIRCGENETICS.114.000606.

PMID:
25516625
14.

Cardiac steatosis potentiates angiotensin II effects in the heart.

Glenn DJ, Cardema MC, Ni W, Zhang Y, Yeghiazarians Y, Grapov D, Fiehn O, Gardner DG.

Am J Physiol Heart Circ Physiol. 2015 Feb 15;308(4):H339-50. doi: 10.1152/ajpheart.00742.2014. Epub 2014 Dec 5.

PMID:
25485904
15.

The use of metabolomics in population-based research.

Su LJ, Fiehn O, Maruvada P, Moore SC, O'Keefe SJ, Wishart DS, Zanetti KA.

Adv Nutr. 2014 Nov 14;5(6):785-8. doi: 10.3945/an.114.006494. Print 2014 Nov.

PMID:
25398741
16.

Identifying individual differences of fluoxetine response in juvenile rhesus monkeys by metabolite profiling.

He Y, Hogrefe CE, Grapov D, Palazoglu M, Fiehn O, Turck CW, Golub MS.

Transl Psychiatry. 2014 Nov 4;4:e478. doi: 10.1038/tp.2014.116.

17.

LipidBlast templates as flexible tools for creating new in-silico tandem mass spectral libraries.

Kind T, Okazaki Y, Saito K, Fiehn O.

Anal Chem. 2014 Nov 18;86(22):11024-7. doi: 10.1021/ac502511a. Epub 2014 Nov 6.

PMID:
25340521
18.
19.

Metabolomics insights into pathophysiological mechanisms of interstitial cystitis.

Fiehn O, Kim J.

Int Neurourol J. 2014 Sep;18(3):106-14. doi: 10.5213/inj.2014.18.3.106. Epub 2014 Sep 24. Review.

20.

MS2Analyzer: A software for small molecule substructure annotations from accurate tandem mass spectra.

Ma Y, Kind T, Yang D, Leon C, Fiehn O.

Anal Chem. 2014 Nov 4;86(21):10724-31. doi: 10.1021/ac502818e. Epub 2014 Oct 14.

PMID:
25263576
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