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Items: 1 to 20 of 204

1.
2.

Hydrogen rearrangement rules: computational MS/MS fragmentation and structure elucidation using MS-FINDER software.

Tsugawa H, Kind T, Nakabayashi R, Yukihira D, Tanaka W, Cajka T, Saito K, Fiehn O, Arita M.

Anal Chem. 2016 Jul 15. [Epub ahead of print]

PMID:
27419259
3.

A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration.

Shahin MH, Gong Y, McDonough CW, Rotroff DM, Beitelshees AL, Garrett TJ, Gums JG, Motsinger-Reif A, Chapman AB, Turner ST, Boerwinkle E, Frye RF, Fiehn O, Cooper-DeHoff RM, Kaddurah-Daouk R, Johnson JA.

Hypertension. 2016 Jul 5. pii: HYPERTENSIONAHA.116.07328. [Epub ahead of print]

PMID:
27381900
4.

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans.

Rotroff DM, Oki NO, Liang X, Yee SW, Stocker SL, Corum DG, Meisner M, Fiehn O, Motsinger-Reif AA, Giacomini KM, Kaddurah-Daouk R.

Front Pharmacol. 2016 Jun 14;7:135. doi: 10.3389/fphar.2016.00135. eCollection 2016.

5.

A family of metal-dependent phosphatases implicated in metabolite damage-control.

Huang L, Khusnutdinova A, Nocek B, Brown G, Xu X, Cui H, Petit P, Flick R, Zallot R, Balmant K, Ziemak MJ, Shanklin J, de Crécy-Lagard V, Fiehn O, Gregory JF 3rd, Joachimiak A, Savchenko A, Yakunin AF, Hanson AD.

Nat Chem Biol. 2016 Aug;12(8):621-7. doi: 10.1038/nchembio.2108. Epub 2016 Jun 20.

PMID:
27322068
6.

Host-mediated sugar oxidation promotes post-antibiotic pathogen expansion.

Faber F, Tran L, Byndloss MX, Lopez CA, Velazquez EM, Kerrinnes T, Nuccio SP, Wangdi T, Fiehn O, Tsolis RM, Bäumler AJ.

Nature. 2016 Jun 30;534(7609):697-9.

PMID:
27309805
7.

Members of a Novel Kinase Family (DUF1537) Can Recycle Toxic Intermediates into an Essential Metabolite.

Thiaville JJ, Flood J, Yurgel S, Prunetti L, Elbadawi-Sidhu M, Hutinet G, Forouhar F, Zhang X, Ganesan V, Reddy P, Fiehn O, Gerlt JA, Hunt JF, Copley SD, de Crécy-Lagard V.

ACS Chem Biol. 2016 Jun 24. [Epub ahead of print]

PMID:
27294475
8.

'Nothing of chemistry disappears in biology': the Top 30 damage-prone endogenous metabolites.

Lerma-Ortiz C, Jeffryes JG, Cooper AJ, Niehaus TD, Thamm AM, Frelin O, Aunins T, Fiehn O, de Crécy-Lagard V, Henry CS, Hanson AD.

Biochem Soc Trans. 2016 Jun 15;44(3):961-71. doi: 10.1042/BST20160073. Review.

PMID:
27284066
9.

Metabolic variations in different citrus rootstock cultivars associated with different responses to Huanglongbing.

Albrecht U, Fiehn O, Bowman KD.

Plant Physiol Biochem. 2016 May 20;107:33-44. doi: 10.1016/j.plaphy.2016.05.030. [Epub ahead of print]

PMID:
27236226
10.

Changes in plasma metabolites and glucose homeostasis during omega-3 polyunsaturated fatty acid supplementation in women with polycystic ovary syndrome.

Karakas SE, Perroud B, Kind T, Palazoglu M, Fiehn O.

BBA Clin. 2016 Apr 13;5:179-85. doi: 10.1016/j.bbacli.2016.04.003. eCollection 2016 Jun.

11.

Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes.

Wang J, Duan Z, Nugent Z, Zou JX, Borowsky AD, Zhang Y, Tepper CG, Li JJ, Fiehn O, Xu J, Kung HJ, Murphy LC, Chen HW.

Cancer Lett. 2016 Aug 10;378(2):69-79. doi: 10.1016/j.canlet.2016.05.004. Epub 2016 May 6.

PMID:
27164560
12.

Distinction of synthetic dl-α-tocopherol from natural vitamin E (d-α-tocopherol) by reversed-phase liquid chromatography. Enhanced selectivity of a polymeric C18 stationary phase at low temperature and/or at high pressure.

Yui Y, Miyazaki S, Ma Y, Ohira M, Fiehn O, Ikegami T, McCalley DV, Tanaka N.

J Chromatogr A. 2016 Jun 10;1450:45-52. doi: 10.1016/j.chroma.2016.04.076. Epub 2016 Apr 27.

PMID:
27157422
13.

Metabolic changes associated with methionine stress sensitivity in MDA-MB-468 breast cancer cells.

Borrego SL, Fahrmann J, Datta R, Stringari C, Grapov D, Zeller M, Chen Y, Wang P, Baldi P, Gratton E, Fiehn O, Kaiser P.

Cancer Metab. 2016 May 2;4:9. doi: 10.1186/s40170-016-0148-6. eCollection 2016.

14.

Plasma amino acid and metabolite signatures tracking diabetes progression in the UCD-T2DM rat model.

Piccolo BD, Graham JL, Stanhope KL, Fiehn O, Havel PJ, Adams SH.

Am J Physiol Endocrinol Metab. 2016 Jun 1;310(11):E958-69. doi: 10.1152/ajpendo.00052.2016. Epub 2016 Apr 19.

PMID:
27094034
15.

Eighteen new oleaginous yeast species.

Garay LA, Sitepu IR, Cajka T, Chandra I, Shi S, Lin T, German JB, Fiehn O, Boundy-Mills KL.

J Ind Microbiol Biotechnol. 2016 Jul;43(7):887-900. doi: 10.1007/s10295-016-1765-3. Epub 2016 Apr 12.

PMID:
27072563
16.

Metabolomics by Gas Chromatography-Mass Spectrometry: Combined Targeted and Untargeted Profiling.

Fiehn O.

Curr Protoc Mol Biol. 2016 Apr 1;114:30.4.1-30.4.32. doi: 10.1002/0471142727.mb3004s114.

PMID:
27038389
17.

Serum phosphatidylethanolamine levels distinguish benign from malignant solitary pulmonary nodules and represent a potential diagnostic biomarker for lung cancer.

Fahrmann JF, Grapov D, DeFelice BC, Taylor S, Kim K, Kelly K, Wikoff WR, Pass H, Rom WN, Fiehn O, Miyamoto S.

Cancer Biomark. 2016 Mar 11;16(4):609-17. doi: 10.3233/CBM-160602.

PMID:
27002763
18.

Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.

Fiehn O, Showalter MR, Schaner-Tooley CE; Reproducibility Project: Cancer Biology; Reproducibility Project Cancer Biology.

Elife. 2016 Feb 26;5. pii: e12626. doi: 10.7554/eLife.12626.

19.

Metabolomic Assessment of Key Maize Resources: GC-MS and NMR Profiling of Grain from B73 Hybrids of the Nested Association Mapping (NAM) Founders and of Geographically Diverse Landraces.

Venkatesh TV, Chassy AW, Fiehn O, Flint-Garcia S, Zeng Q, Skogerson K, Harrigan GG.

J Agric Food Chem. 2016 Mar 16;64(10):2162-72. doi: 10.1021/acs.jafc.5b04901. Epub 2016 Mar 7.

PMID:
26923484
20.

Evidence That COG0325 Proteins are involved in PLP Homeostasis.

Prunetti L, El Yacoubi B, Schiavon CR, Kirkpatrick E, Huang L, Bailly M, ElBadawi-Sidhu M, Harrison K, Gregory JF, Fiehn O, Hanson AD, de Crécy-Lagard V.

Microbiology. 2016 Feb 12. doi: 10.1099/mic.0.000255. [Epub ahead of print]

PMID:
26872910
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