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Results: 1 to 20 of 35

1.

Concentration-effect modeling based on change from baseline to assess the prolonging effect of drugs on QTc together with an estimate of the circadian time course.

Ferber G, Wang D, Täubel J.

J Clin Pharmacol. 2014 Jun 17. doi: 10.1002/jcph.347. [Epub ahead of print]

PMID:
24935561
[PubMed - as supplied by publisher]
2.

Analyzing the relationship of QT interval and exposure to Nitazoxanide, a prospective candidate for influenza antiviral therapy-A formal TQT study.

Täubel J, Lorch U, Rossignol JF, Ferber G, John Camm A.

J Clin Pharmacol. 2014 Apr 1. doi: 10.1002/jcph.300. [Epub ahead of print]

PMID:
24691901
[PubMed - as supplied by publisher]
3.

Importance of subject-specific QT/RR curvatures in the design of individual heart rate corrections of the QT interval.

Ferber G, Zhou M M, Darpo B.

J Electrocardiol. 2014 May-Jun;47(3):385-6. doi: 10.1016/j.jelectrocard.2013.12.010. Epub 2013 Dec 28. No abstract available.

PMID:
24468293
[PubMed - in process]
4.

The IQ-CSRC prospective clinical Phase 1 study: "Can early QT assessment using exposure response analysis replace the thorough QT study?".

Darpo B, Sarapa N, Garnett C, Benson C, Dota C, Ferber G, Jarugula V, Johannesen L, Keirns J, Krudys K, Ortemann-Renon C, Riley S, Rogers-Subramaniam D, Stockbridge N.

Ann Noninvasive Electrocardiol. 2014 Jan;19(1):70-81. doi: 10.1111/anec.12128. Epub 2013 Dec 30.

PMID:
24372708
[PubMed - in process]
5.

Lomitapide at supratherapeutic plasma levels does not prolong the Qtc interval--results from a TQT study with moxifloxacin and ketoconazole.

Darpo B, Ferber G, Zhou M, Sumeray M, Sager P.

Ann Noninvasive Electrocardiol. 2013 Nov;18(6):577-89. doi: 10.1111/anec.12103. Epub 2013 Sep 30.

PMID:
24118671
[PubMed - in process]
6.

Thorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjects.

Taubel J, Ferber G, Lorch U, Batchvarov V, Savelieva I, Camm AJ.

Br J Clin Pharmacol. 2014 Jan;77(1):170-9. doi: 10.1111/bcp.12168.

PMID:
23713767
[PubMed - in process]
7.

Preclinical QT safety assessment: cross-species comparisons and human translation from an industry consortium.

Holzgrefe H, Ferber G, Champeroux P, Gill M, Honda M, Greiter-Wilke A, Baird T, Meyer O, Saulnier M.

J Pharmacol Toxicol Methods. 2014 Jan-Feb;69(1):61-101. doi: 10.1016/j.vascn.2013.05.004. Epub 2013 May 17.

PMID:
23689033
[PubMed - in process]
Free Article
8.

Assessment of the cardiac safety and pharmacokinetics of a short course, twice daily dose of orally-administered mifepristone in healthy male subjects.

Darpo B, Bullingham R, Combs DL, Ferber G, Hafez K.

Cardiol J. 2013;20(2):152-60. doi: 10.5603/CJ.2013.0028.

PMID:
23558873
[PubMed - in process]
Free Article
9.

Pattern recognition analysis of digital ECGs: decreased QT measurement error and improved precision compared to semi-automated methods.

Meyer O, Ferber G, Greig G, Holzgrefe HH.

J Electrocardiol. 2013 Mar-Apr;46(2):118-25. doi: 10.1016/j.jelectrocard.2012.11.012. Epub 2012 Dec 22.

PMID:
23266069
[PubMed - indexed for MEDLINE]
10.

Insulin at normal physiological levels does not prolong QT(c) interval in thorough QT studies performed in healthy volunteers.

Taubel J, Lorch U, Ferber G, Singh J, Batchvarov VN, Savelieva I, Camm AJ.

Br J Clin Pharmacol. 2013 Feb;75(2):392-403. doi: 10.1111/j.1365-2125.2012.04376.x.

PMID:
22775199
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects (pages.

Sugiyama A, Nakamura Y, Nishimura S, Adachi-Akahane S, Kumagai Y, Gayed J, Naseem A, Ferber G, Taubel J, Camm J.

Br J Clin Pharmacol. 2012 Mar;73(3):455-9.

PMID:
22442827
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Shortening of the QT interval after food can be used to demonstrate assay sensitivity in thorough QT studies.

Taubel J, Wong AH, Naseem A, Ferber G, Camm AJ.

J Clin Pharmacol. 2012 Oct;52(10):1558-65. Epub 2011 Nov 8.

PMID:
22067197
[PubMed - indexed for MEDLINE]
14.

Structured multiplicity and confirmatory statistical analyses in pharmacodynamic studies using the quantitative electroencephalogram.

Ferber G, Staner L, Boeijinga P.

J Neurosci Methods. 2011 Sep 30;201(1):204-12. doi: 10.1016/j.jneumeth.2011.07.001. Epub 2011 Jul 18.

PMID:
21782848
[PubMed - indexed for MEDLINE]
15.

Characterization of the human QT interval: novel distribution-based assessment of the repolarization effects of moxifloxacin.

Holzgrefe HH, Ferber G, Morrison R, Meyer O, Greiter-Wilke A, Singer T.

J Clin Pharmacol. 2012 Aug;52(8):1222-39. doi: 10.1177/0091270011409234. Epub 2011 Jun 9.

PMID:
21659628
[PubMed - indexed for MEDLINE]
16.

QT/QTc prolongation in placebo-treated subjects: a PhRMA collaborative data analysis.

Agin MA, Aronstein WS, Ferber G, Geraldes MC, Locke C, Sager P.

J Biopharm Stat. 2008;18(3):408-26. doi: 10.1080/10543400801992962.

PMID:
18470753
[PubMed - indexed for MEDLINE]
17.

Biomarkers and proof of concept.

Ferber G.

Methods Find Exp Clin Pharmacol. 2002;24 Suppl C:35-40. Review.

PMID:
12575486
[PubMed - indexed for MEDLINE]
18.

[German-Latvian cooperation in the pathology specialty].

Ferber G, Müller KM.

Pathologe. 1999 Jul;20(4):251-4. German.

PMID:
10478368
[PubMed - indexed for MEDLINE]
19.

IPEG guideline on statistical design and analysis for pharmacodynamic trials. International Pharmaco-EEG Group.

Ferber G, Abt K, Fichte K, Luthringer R.

Neuropsychobiology. 1999;39(2):92-100. No abstract available.

PMID:
10072666
[PubMed - indexed for MEDLINE]
20.

[Use of automatic, computer-assisted EEG analysis in clinical practice].

Hinrichs H, Feistner H, Awiszus F, Ferber G, Heinze HJ.

Fortschr Neurol Psychiatr. 1997 Aug;65(8):354-60. German.

PMID:
9378448
[PubMed - indexed for MEDLINE]

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