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Results: 1 to 20 of 26


Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics.

Guilhamon P, Butcher LM, Presneau N, Wilson GA, Feber A, Paul DS, Schütte M, Haybaeck J, Keilholz U, Hoffman J, Ross MT, Flanagan AM, Beck S.

Genome Med. 2014 Dec 12;6(12):116. doi: 10.1186/s13073-014-0116-0. eCollection 2014.


Epigenetics Markers of Metastasis and HPV-Induced Tumorigenesis in Penile Cancer.

Feber A, Arya M, de Winter P, Saqib M, Nigam R, Malone PR, Tan WS, Rodney S, Lechner M, Freeman A, Jameson C, Muneer A, Beck S, Kelly JD.

Clin Cancer Res. 2015 Mar 1;21(5):1196-206. doi: 10.1158/1078-0432.CCR-14-1656. Epub 2014 Dec 23.


Loss of expression of the tumour suppressor gene AIMP3 predicts survival following radiotherapy in muscle-invasive bladder cancer.

Gurung PM, Veerakumarasivam A, Williamson M, Counsell N, Douglas J, Tan WS, Feber A, Crabb SJ, Short SC, Freeman A, Powles T, Hoskin PJ, West CM, Kelly JD.

Int J Cancer. 2015 Feb 1;136(3):709-20. doi: 10.1002/ijc.29022. Epub 2014 Jul 22.


Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases.

Wilson GA, Butcher LM, Foster HR, Feber A, Roos C, Walter L, Woszczek G, Beck S, Bell CG.

Genome Med. 2014 Mar 5;6(3):19. doi: 10.1186/gm536. eCollection 2014.


Assessment of RainDrop BS-seq as a method for large-scale, targeted bisulfite sequencing.

Paul DS, Guilhamon P, Karpathakis A, Butcher LM, Thirlwell C, Feber A, Beck S.

Epigenetics. 2014 May;9(5):678-84. doi: 10.4161/epi.28041. Epub 2014 Feb 11.


Using high-density DNA methylation arrays to profile copy number alterations.

Feber A, Guilhamon P, Lechner M, Fenton T, Wilson GA, Thirlwell C, Morris TJ, Flanagan AM, Teschendorff AE, Kelly JD, Beck S.

Genome Biol. 2014 Feb 3;15(2):R30. doi: 10.1186/gb-2014-15-2-r30.


ChAMP: 450k Chip Analysis Methylation Pipeline.

Morris TJ, Butcher LM, Feber A, Teschendorff AE, Chakravarthy AR, Wojdacz TK, Beck S.

Bioinformatics. 2014 Feb 1;30(3):428-30. doi: 10.1093/bioinformatics/btt684. Epub 2013 Dec 12.


Integrated virus-host methylome analysis in head and neck squamous cell carcinoma.

Wilson GA, Lechner M, Köferle A, Caren H, Butcher LM, Feber A, Fenton T, Jay A, Boshoff C, Beck S.

Epigenetics. 2013 Sep;8(9):953-61. doi: 10.4161/epi.25614. Epub 2013 Jul 18.


Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2.

Guilhamon P, Eskandarpour M, Halai D, Wilson GA, Feber A, Teschendorff AE, Gomez V, Hergovich A, Tirabosco R, Fernanda Amary M, Baumhoer D, Jundt G, Ross MT, Flanagan AM, Beck S.

Nat Commun. 2013;4:2166. doi: 10.1038/ncomms3166.


Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors.

Lechner M, Frampton GM, Fenton T, Feber A, Palmer G, Jay A, Pillay N, Forster M, Cronin MT, Lipson D, Miller VA, Brennan TA, Henderson S, Vaz F, O'Flynn P, Kalavrezos N, Yelensky R, Beck S, Stephens PJ, Boshoff C.

Genome Med. 2013 May 29;5(5):49. doi: 10.1186/gm453. eCollection 2013.


Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner.

Stricker SH, Feber A, Engström PG, Carén H, Kurian KM, Takashima Y, Watts C, Way M, Dirks P, Bertone P, Smith A, Beck S, Pollard SM.

Genes Dev. 2013 Mar 15;27(6):654-69. doi: 10.1101/gad.212662.112.


Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.

Lechner M, Fenton T, West J, Wilson G, Feber A, Henderson S, Thirlwell C, Dibra HK, Jay A, Butcher L, Chakravarthy AR, Gratrix F, Patel N, Vaz F, O'Flynn P, Kalavrezos N, Teschendorff AE, Boshoff C, Beck S.

Genome Med. 2013 Feb 5;5(2):15. doi: 10.1186/gm419. eCollection 2013.


Comments on: Interpretation of genome-wide infinium methylation data from ligated DNA in formalin-fixed paraffin-embedded paired tumor and normal tissue.

Thirlwell C, Feber A, Lechner M, Teschendorff AE, Beck S.

BMC Res Notes. 2012 Nov 13;5:631. doi: 10.1186/1756-0500-5-631.


A functional methylome map of ulcerative colitis.

Häsler R, Feng Z, Bäckdahl L, Spehlmann ME, Franke A, Teschendorff A, Rakyan VK, Down TA, Wilson GA, Feber A, Beck S, Schreiber S, Rosenstiel P.

Genome Res. 2012 Nov;22(11):2130-7. doi: 10.1101/gr.138347.112. Epub 2012 Jul 23.


Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers.

Wilson GA, Dhami P, Feber A, Cortázar D, Suzuki Y, Schulz R, Schär P, Beck S.

Gigascience. 2012 Jul 12;1(1):3. doi: 10.1186/2047-217X-1-3.


MicroRNA prognostic signature for nodal metastases and survival in esophageal adenocarcinoma.

Feber A, Xi L, Pennathur A, Gooding WE, Bandla S, Wu M, Luketich JD, Godfrey TE, Litle VR.

Ann Thorac Surg. 2011 May;91(5):1523-30. doi: 10.1016/j.athoracsur.2011.01.056. Epub 2011 Mar 21.


Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors.

Feber A, Wilson GA, Zhang L, Presneau N, Idowu B, Down TA, Rakyan VK, Noon LA, Lloyd AC, Stupka E, Schiza V, Teschendorff AE, Schroth GP, Flanagan A, Beck S.

Genome Res. 2011 Apr;21(4):515-24. doi: 10.1101/gr.109678.110. Epub 2011 Feb 1.


Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip.

Thirlwell C, Eymard M, Feber A, Teschendorff A, Pearce K, Lechner M, Widschwendter M, Beck S.

Methods. 2010 Nov;52(3):248-54. doi: 10.1016/j.ymeth.2010.04.012. Epub 2010 Apr 29. Review.


Association between CCND1 G/A870 polymorphism, allele-specific amplification, cyclin D1 expression, and survival in esophageal and lung carcinoma.

Gupta VK, Feber A, Xi L, Pennathur A, Wu M, Luketich JD, Godfrey TE.

Clin Cancer Res. 2008 Dec 1;14(23):7804-12. doi: 10.1158/1078-0432.CCR-08-0744.


Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer.

Xi L, Feber A, Gupta V, Wu M, Bergemann AD, Landreneau RJ, Litle VR, Pennathur A, Luketich JD, Godfrey TE.

Nucleic Acids Res. 2008 Nov;36(20):6535-47. doi: 10.1093/nar/gkn697. Epub 2008 Oct 16.

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