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Results: 1 to 20 of 64


Discovery and confirmation of a protein biomarker panel with potential to predict response to biological therapy in psoriatic arthritis.

Ademowo OS, Hernandez B, Collins E, Rooney C, Fearon U, van Kuijk AW, Tak PP, Gerlag DM, FitzGerald O, Pennington SR.

Ann Rheum Dis. 2014 Sep 3. pii: annrheumdis-2014-205417. doi: 10.1136/annrheumdis-2014-205417. [Epub ahead of print]


Redox-mediated angiogenesis in the hypoxic joint of inflammatory arthritis.

Biniecka M, Connolly M, Gao W, Ng CT, Balogh E, Gogarty M, Santos L, Murphy E, Brayden D, Veale DJ, Fearon U.

Arthritis Rheumatol. 2014 Dec;66(12):3300-10. doi: 10.1002/art.38822.


Hypoxia and STAT3 signalling interactions regulate pro-inflammatory pathways in rheumatoid arthritis.

Gao W, McCormick J, Connolly M, Balogh E, Veale DJ, Fearon U.

Ann Rheum Dis. 2014 Feb 13. doi: 10.1136/annrheumdis-2013-204105. [Epub ahead of print]


Comparison of remission criteria in a tumour necrosis factor inhibitor treated rheumatoid arthritis longitudinal cohort: patient global health is a confounder.

Balogh E, Madruga Dias J, Orr C, Mullan R, Harty L, FitzGerald O, Gallagher P, Molloy M, O'Flynn E, Kelly A, Minnock P, O'Neill M, Moore L, Murray M, Fearon U, Veale DJ.

Arthritis Res Ther. 2013 Dec 24;15(6):R221. doi: 10.1186/ar4421.


Notch-1 mediates endothelial cell activation and invasion in psoriasis.

Rooney P, Connolly M, Gao W, McCormick J, Biniecka M, Sullivan O, Kirby B, Sweeney C, Molloy E, Markham T, Fearon U, Veale DJ.

Exp Dermatol. 2014 Feb;23(2):113-8. doi: 10.1111/exd.12306.


Hypoxia: how does the monocyte-macrophage system respond to changes in oxygen availability?

Strehl C, Fangradt M, Fearon U, Gaber T, Buttgereit F, Veale DJ.

J Leukoc Biol. 2014 Feb;95(2):233-41. doi: 10.1189/jlb.1212627. Epub 2013 Oct 29. Review.


Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered NR4A2 activity.

McMorrow JP, Crean D, Gogarty M, Smyth A, Connolly M, Cummins E, Veale D, Fearon U, Tak PP, Fitzgerald O, Murphy EP.

Am J Pathol. 2013 Oct;183(4):1243-57. doi: 10.1016/j.ajpath.2013.06.029. Epub 2013 Aug 6.


Notch signalling pathways mediate synovial angiogenesis in response to vascular endothelial growth factor and angiopoietin 2.

Gao W, Sweeney C, Walsh C, Rooney P, McCormick J, Veale DJ, Fearon U.

Ann Rheum Dis. 2013 Jun;72(6):1080-8. doi: 10.1136/annrheumdis-2012-201978. Epub 2012 Nov 17.


Is the serum amyloid A we use really serum amyloid A? Comment on the article by Connolly et al. Reply.

Mullan RH, Connolly M, Veale DJ, Fearon U.

Arthritis Rheum. 2013 Jan;65(1):284-5. doi: 10.1002/art.37736. No abstract available.


Elevated circulating osteoprotegerin and reduced matrix-metalloprotease-9 in post-menopausal women with chronic Hepatitis C virus infection.

Nanda KS, Brady JJ, Murray BF, Sullivan O, Fearon U, McKenna MJ, Hegarty JE, O'Farrelly C, Ryan EJ.

Cytokine. 2012 Nov;60(2):328-33. doi: 10.1016/j.cyto.2012.07.006. Epub 2012 Aug 3.


Histamine contributes to increased RANKL to osteoprotegerin ratio through altered nuclear receptor 4A activity in human chondrocytes.

Marzaioli V, McMorrow JP, Angerer H, Gilmore A, Crean D, Zocco D, Rooney P, Veale D, Fearon U, Gogarty M, McEvoy AN, Stradner MH, Murphy EP.

Arthritis Rheum. 2012 Oct;64(10):3290-301. doi: 10.1002/art.34554.


Orphan nuclear receptor NR4A2 induces synoviocyte proliferation, invasion, and matrix metalloproteinase 13 transcription.

Mix KS, McMahon K, McMorrow JP, Walkenhorst DE, Smyth AM, Petrella BL, Gogarty M, Fearon U, Veale D, Attur MG, Abramson SB, Murphy EP.

Arthritis Rheum. 2012 Jul;64(7):2126-36. doi: 10.1002/art.34399.


Notch-1 mediates hypoxia-induced angiogenesis in rheumatoid arthritis.

Gao W, Sweeney C, Connolly M, Kennedy A, Ng CT, McCormick J, Veale DJ, Fearon U.

Arthritis Rheum. 2012 Jul;64(7):2104-13. doi: 10.1002/art.34397.


The pattern-recognition receptor nucleotide-binding oligomerization domain--containing protein 1 promotes production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts.

Yokota K, Miyazaki T, Hemmatazad H, Gay RE, Kolling C, Fearon U, Suzuki H, Mimura T, Gay S, Ospelt C.

Arthritis Rheum. 2012 May;64(5):1329-37. doi: 10.1002/art.34318.


Mitochondrial mutagenesis correlates with the local inflammatory environment in arthritis.

Harty LC, Biniecka M, O'Sullivan J, Fox E, Mulhall K, Veale DJ, Fearon U.

Ann Rheum Dis. 2012 Apr;71(4):582-8. doi: 10.1136/annrheumdis-2011-200245. Epub 2011 Nov 25.


Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease.

Walsh CE, Ryan EJ, O'Farrelly C, Golden-Mason L, FitzGerald O, Veale DJ, Bresnihan B, Fearon U.

PLoS One. 2011;6(11):e27182. doi: 10.1371/journal.pone.0027182. Epub 2011 Nov 15.


Acute-phase serum amyloid A regulates tumor necrosis factor α and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy.

Connolly M, Mullan RH, McCormick J, Matthews C, Sullivan O, Kennedy A, FitzGerald O, Poole AR, Bresnihan B, Veale DJ, Fearon U.

Arthritis Rheum. 2012 Apr;64(4):1035-45. doi: 10.1002/art.33455. Epub 2011 Nov 10.


IL-17A expression is localised to both mononuclear and polymorphonuclear synovial cell infiltrates.

Moran EM, Heydrich R, Ng CT, Saber TP, McCormick J, Sieper J, Appel H, Fearon U, Veale DJ.

PLoS One. 2011;6(8):e24048. doi: 10.1371/journal.pone.0024048. Epub 2011 Aug 24.


Toll-like receptor 2 induced angiogenesis and invasion is mediated through the Tie2 signalling pathway in rheumatoid arthritis.

Saber T, Veale DJ, Balogh E, McCormick J, NicAnUltaigh S, Connolly M, Fearon U.

PLoS One. 2011;6(8):e23540. doi: 10.1371/journal.pone.0023540. Epub 2011 Aug 17.


Interleukin-17A induction of angiogenesis, cell migration, and cytoskeletal rearrangement.

Moran EM, Connolly M, Gao W, McCormick J, Fearon U, Veale DJ.

Arthritis Rheum. 2011 Nov;63(11):3263-73. doi: 10.1002/art.30582.

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