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Results: 1 to 20 of 51


The SM protein Sly1 accelerates assembly of the ER-Golgi SNARE complex.

Demircioglu FE, Burkhardt P, Fasshauer D.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13828-33. doi: 10.1073/pnas.1408254111. Epub 2014 Sep 4.


Novel cell types, neurosecretory cells, and body plan of the early-diverging metazoan Trichoplax adhaerens.

Smith CL, Varoqueaux F, Kittelmann M, Azzam RN, Cooper B, Winters CA, Eitel M, Fasshauer D, Reese TS.

Curr Biol. 2014 Jul 21;24(14):1565-72. doi: 10.1016/j.cub.2014.05.046. Epub 2014 Jun 19.


Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation.

Colbert KN, Hattendorf DA, Weiss TM, Burkhardt P, Fasshauer D, Weis WI.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12637-42. doi: 10.1073/pnas.1303753110. Epub 2013 Jul 15.


Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment.

Honigmann A, van den Bogaart G, Iraheta E, Risselada HJ, Milovanovic D, Mueller V, Müllar S, Diederichsen U, Fasshauer D, Grubmüller H, Hell SW, Eggeling C, Kühnel K, Jahn R.

Nat Struct Mol Biol. 2013 Jun;20(6):679-86. doi: 10.1038/nsmb.2570. Epub 2013 May 12.


Molecular machines governing exocytosis of synaptic vesicles.

Jahn R, Fasshauer D.

Nature. 2012 Oct 11;490(7419):201-7. doi: 10.1038/nature11320. Review.


Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis.

Klöpper TH, Kienle N, Fasshauer D, Munro S.

BMC Biol. 2012 Aug 8;10:71. doi: 10.1186/1741-7007-10-71.


Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission.

Meijer M, Burkhardt P, de Wit H, Toonen RF, Fasshauer D, Verhage M.

EMBO J. 2012 May 2;31(9):2156-68. doi: 10.1038/emboj.2012.72. Epub 2012 Mar 23.


Primordial neurosecretory apparatus identified in the choanoflagellate Monosiga brevicollis.

Burkhardt P, Stegmann CM, Cooper B, Kloepper TH, Imig C, Varoqueaux F, Wahl MC, Fasshauer D.

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15264-9. doi: 10.1073/pnas.1106189108. Epub 2011 Aug 29.


A coiled coil trigger site is essential for rapid binding of synaptobrevin to the SNARE acceptor complex.

Wiederhold K, Kloepper TH, Walter AM, Stein A, Kienle N, Sørensen JB, Fasshauer D.

J Biol Chem. 2010 Jul 9;285(28):21549-59. doi: 10.1074/jbc.M110.105148. Epub 2010 Apr 20.


Synaptobrevin N-terminally bound to syntaxin-SNAP-25 defines the primed vesicle state in regulated exocytosis.

Walter AM, Wiederhold K, Bruns D, Fasshauer D, Sørensen JB.

J Cell Biol. 2010 Feb 8;188(3):401-13. doi: 10.1083/jcb.200907018.


A conserved membrane attachment site in alpha-SNAP facilitates N-ethylmaleimide-sensitive factor (NSF)-driven SNARE complex disassembly.

Winter U, Chen X, Fasshauer D.

J Biol Chem. 2009 Nov 13;284(46):31817-26. doi: 10.1074/jbc.M109.045286. Epub 2009 Sep 17.


Single vesicle millisecond fusion kinetics reveals number of SNARE complexes optimal for fast SNARE-mediated membrane fusion.

Domanska MK, Kiessling V, Stein A, Fasshauer D, Tamm LK.

J Biol Chem. 2009 Nov 13;284(46):32158-66. doi: 10.1074/jbc.M109.047381. Epub 2009 Sep 15. Erratum in: J Biol Chem. 2010 Apr 9;285(15):11754.


The Ca2+ affinity of synaptotagmin 1 is markedly increased by a specific interaction of its C2B domain with phosphatidylinositol 4,5-bisphosphate.

Radhakrishnan A, Stein A, Jahn R, Fasshauer D.

J Biol Chem. 2009 Sep 18;284(38):25749-60. doi: 10.1074/jbc.M109.042499. Epub 2009 Jul 24.


Differences in the SNARE evolution of fungi and metazoa.

Kienle N, Kloepper TH, Fasshauer D.

Biochem Soc Trans. 2009 Aug;37(Pt 4):787-91. doi: 10.1042/BST0370787. Review.


Is assembly of the SNARE complex enough to fuel membrane fusion?

Wiederhold K, Fasshauer D.

J Biol Chem. 2009 May 8;284(19):13143-52. doi: 10.1074/jbc.M900703200. Epub 2009 Mar 3.


Phylogeny of the SNARE vesicle fusion machinery yields insights into the conservation of the secretory pathway in fungi.

Kienle N, Kloepper TH, Fasshauer D.

BMC Evol Biol. 2009 Jan 23;9:19. doi: 10.1186/1471-2148-9-19.


Imaging the assembly and disassembly kinetics of cis-SNARE complexes on native plasma membranes.

Bar-On D, Winter U, Nachliel E, Gutman M, Fasshauer D, Lang T, Ashery U.

FEBS Lett. 2008 Oct 15;582(23-24):3563-8. doi: 10.1016/j.febslet.2008.08.040. Epub 2008 Sep 24.


SNAREing the basis of multicellularity: consequences of protein family expansion during evolution.

Kloepper TH, Kienle CN, Fasshauer D.

Mol Biol Evol. 2008 Sep;25(9):2055-68. doi: 10.1093/molbev/msn151. Epub 2008 Jul 10.


Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide.

Burkhardt P, Hattendorf DA, Weis WI, Fasshauer D.

EMBO J. 2008 Apr 9;27(7):923-33. doi: 10.1038/emboj.2008.37. Epub 2008 Mar 13.


A novel site of action for alpha-SNAP in the SNARE conformational cycle controlling membrane fusion.

Barszczewski M, Chua JJ, Stein A, Winter U, Heintzmann R, Zilly FE, Fasshauer D, Lang T, Jahn R.

Mol Biol Cell. 2008 Mar;19(3):776-84. Epub 2007 Dec 19.

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