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Items: 1 to 20 of 22


Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection.

Wilson GK, Farquhar MJ, Meredith L, Dhawan A, Mitry R, Balfe P, McKeating JA.

J Gen Virol. 2015 Jun;96(Pt 6):1369-73. doi: 10.1099/vir.0.000085. Epub 2015 Feb 9.


Type I interferon rapidly restricts infectious hepatitis C virus particle genesis.

Meredith LW, Farquhar MJ, Tarr AW, McKeating JA.

Hepatology. 2014 Dec;60(6):1891-901. doi: 10.1002/hep.27333. Epub 2014 Oct 27.


A role for CD81 and hepatitis C virus in hepatoma mobility.

Brimacombe CL, Wilson GK, Hübscher SG, McKeating JA, Farquhar MJ.

Viruses. 2014 Mar 24;6(3):1454-72. doi: 10.3390/v6031454.


Production, purification and characterization of recombinant, full-length human claudin-1.

Bonander N, Jamshad M, Oberthür D, Clare M, Barwell J, Hu K, Farquhar MJ, Stamataki Z, Harris HJ, Dierks K, Dafforn TR, Betzel C, McKeating JA, Bill RM.

PLoS One. 2013 May 21;8(5):e64517. doi: 10.1371/journal.pone.0064517. Print 2013.


Hepatoma polarization limits CD81 and hepatitis C virus dynamics.

Harris HJ, Clerte C, Farquhar MJ, Goodall M, Hu K, Rassam P, Dosset P, Wilson GK, Balfe P, Ijzendoorn SC, Milhiet PE, McKeating JA.

Cell Microbiol. 2013 Mar;15(3):430-45. doi: 10.1111/cmi.12047. Epub 2012 Nov 20.


Hepatitis C virus induces CD81 and claudin-1 endocytosis.

Farquhar MJ, Hu K, Harris HJ, Davis C, Brimacombe CL, Fletcher SJ, Baumert TF, Rappoport JZ, Balfe P, McKeating JA.

J Virol. 2012 Apr;86(8):4305-16. doi: 10.1128/JVI.06996-11. Epub 2012 Feb 8.


Nicotine self-administered directly into the VTA by rats is weakly reinforcing but has strong reinforcement enhancing properties.

Farquhar MJ, Latimer MP, Winn P.

Psychopharmacology (Berl). 2012 Mar;220(1):43-54. doi: 10.1007/s00213-011-2452-8. Epub 2011 Sep 6.


Structural characterization of CD81-Claudin-1 hepatitis C virus receptor complexes.

Bonander N, Jamshad M, Hu K, Farquhar MJ, Stamataki Z, Balfe P, McKeating JA, Bill RM.

Biochem Soc Trans. 2011 Apr;39(2):537-40. doi: 10.1042/BST0390537. Review.


Hepatitis C virus entry and the tetraspanin CD81.

Farquhar MJ, Harris HJ, McKeating JA.

Biochem Soc Trans. 2011 Apr;39(2):532-6. doi: 10.1042/BST0390532. Review.


Hepatitis C virus infection of neuroepithelioma cell lines.

Fletcher NF, Yang JP, Farquhar MJ, Hu K, Davis C, He Q, Dowd K, Ray SC, Krieger SE, Neyts J, Baumert TF, Balfe P, McKeating JA, Wong-Staal F.

Gastroenterology. 2010 Oct;139(4):1365-74. doi: 10.1053/j.gastro.2010.06.008. Epub 2010 Jun 9.


Claudin association with CD81 defines hepatitis C virus entry.

Harris HJ, Davis C, Mullins JG, Hu K, Goodall M, Farquhar MJ, Mee CJ, McCaffrey K, Young S, Drummer H, Balfe P, McKeating JA.

J Biol Chem. 2010 Jul 2;285(27):21092-102. doi: 10.1074/jbc.M110.104836. Epub 2010 Apr 7.


Hepatitis C virus infection reduces hepatocellular polarity in a vascular endothelial growth factor-dependent manner.

Mee CJ, Farquhar MJ, Harris HJ, Hu K, Ramma W, Ahmed A, Maurel P, Bicknell R, Balfe P, McKeating JA.

Gastroenterology. 2010 Mar;138(3):1134-42. doi: 10.1053/j.gastro.2009.11.047. Epub 2009 Nov 26.


Polarization restricts hepatitis C virus entry into HepG2 hepatoma cells.

Mee CJ, Harris HJ, Farquhar MJ, Wilson G, Reynolds G, Davis C, van IJzendoorn SC, Balfe P, McKeating JA.

J Virol. 2009 Jun;83(12):6211-21. doi: 10.1128/JVI.00246-09. Epub 2009 Apr 8.


Primary hepatocytes as targets for hepatitis C virus replication.

Farquhar MJ, McKeating JA.

J Viral Hepat. 2008 Dec;15(12):849-54. doi: 10.1111/j.1365-2893.2008.01051.x. Review.


Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity.

Farquhar MJ, Harris HJ, Diskar M, Jones S, Mee CJ, Nielsen SU, Brimacombe CL, Molina S, Toms GL, Maurel P, Howl J, Herberg FW, van Ijzendoorn SC, Balfe P, McKeating JA.

J Virol. 2008 Sep;82(17):8797-811. doi: 10.1128/JVI.00592-08. Epub 2008 Jun 25.


CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry.

Harris HJ, Farquhar MJ, Mee CJ, Davis C, Reynolds GM, Jennings A, Hu K, Yuan F, Deng H, Hubscher SG, Han JH, Balfe P, McKeating JA.

J Virol. 2008 May;82(10):5007-20. doi: 10.1128/JVI.02286-07. Epub 2008 Mar 12.


Identification of caspase 3 motifs and critical aspartate residues in human phospholipase D1b and phospholipase D2a.

Wright MH, Farquhar MJ, Aletrari MO, Ladds G, Hodgkin MN.

Biochem Biophys Res Commun. 2008 May 2;369(2):478-84. doi: 10.1016/j.bbrc.2008.02.064. Epub 2008 Feb 25.


The pedunculopontine tegmental nucleus and the nucleus basalis magnocellularis: do both have a role in sustained attention?

Rostron CL, Farquhar MJ, Latimer MP, Winn P.

BMC Neurosci. 2008 Jan 30;9:16. doi: 10.1186/1471-2202-9-16.


Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies.

Timpe JM, Stamataki Z, Jennings A, Hu K, Farquhar MJ, Harris HJ, Schwarz A, Desombere I, Roels GL, Balfe P, McKeating JA.

Hepatology. 2008 Jan;47(1):17-24.


Interaction of PLD1b with actin in antigen-stimulated mast cells.

Farquhar MJ, Powner DJ, Levine BA, Wright MH, Ladds G, Hodgkin MN.

Cell Signal. 2007 Feb;19(2):349-58. Epub 2006 Jul 28.

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