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Results: 1 to 20 of 27

1.

Sparse generalized functional linear model for predicting remission status of depression patients.

Liu Y, Nie Z, Zhou J, Farnum M, Narayan VA, Wittenberg G, Ye J.

Pac Symp Biocomput. 2014:364-75.

PMID:
24297562
[PubMed - indexed for MEDLINE]
Free Article
2.

The ADAS-Cog revisited: novel composite scales based on ADAS-Cog to improve efficiency in MCI and early AD trials.

Raghavan N, Samtani MN, Farnum M, Yang E, Novak G, Grundman M, Narayan V, DiBernardo A; Alzheimer’s Disease Neuroimaging Initiative.

Alzheimers Dement. 2013 Feb;9(1 Suppl):S21-31. doi: 10.1016/j.jalz.2012.05.2187. Epub 2012 Nov 2.

PMID:
23127469
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Sparse learning and stability selection for predicting MCI to AD conversion using baseline ADNI data.

Ye J, Farnum M, Yang E, Verbeeck R, Lobanov V, Raghavan N, Novak G, DiBernardo A, Narayan VA; Alzheimer’s Disease Neuroimaging Initiative.

BMC Neurol. 2012 Jun 25;12:46. doi: 10.1186/1471-2377-12-46.

PMID:
22731740
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A novel subject synchronization clinical trial design for Alzheimer's disease.

Schultz T, Yang E, Farnum M, Lobanov V, Verbeeck R, Raghavan N, Samtani MN, Novak G, Shi Y, Narayan V, DiBernardo A.

J Alzheimers Dis. 2012;31(3):507-16. doi: 10.3233/JAD-2012-120286. Review.

PMID:
22614878
[PubMed - indexed for MEDLINE]
5.

Disease progression model in subjects with mild cognitive impairment from the Alzheimer's disease neuroimaging initiative: CSF biomarkers predict population subtypes.

Samtani MN, Raghavan N, Shi Y, Novak G, Farnum M, Lobanov V, Schultz T, Yang E, DiBernardo A, Narayan VA; Alzheimer's Disease Neuroimaging Initiative.

Br J Clin Pharmacol. 2013 Jan;75(1):146-61. doi: 10.1111/j.1365-2125.2012.04308.x.

PMID:
22534009
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Efficient substructure searching of large chemical libraries: the ABCD chemical cartridge.

Agrafiotis DK, Lobanov VS, Shemanarev M, Rassokhin DN, Izrailev S, Jaeger EP, Alex S, Farnum M.

J Chem Inf Model. 2011 Dec 27;51(12):3113-30. doi: 10.1021/ci200413e. Epub 2011 Nov 14.

PMID:
22035187
[PubMed - indexed for MEDLINE]
7.

Quantifying the pathophysiological timeline of Alzheimer's disease.

Yang E, Farnum M, Lobanov V, Schultz T, Verbeeck R, Raghavan N, Samtani MN, Novak G, Narayan V, DiBernardo A; Alzheimer's Disease Neuroimaging Initiative.

J Alzheimers Dis. 2011;26(4):745-53. doi: 10.3233/JAD-2011-110551. Erratum in: J Alzheimers Dis. 2011;27(4):923. Verbeeck, Rudi [added].

PMID:
21694449
[PubMed - indexed for MEDLINE]
8.

An improved model for disease progression in patients from the Alzheimer's disease neuroimaging initiative.

Samtani MN, Farnum M, Lobanov V, Yang E, Raghavan N, Dibernardo A, Narayan V; Alzheimer’s Disease Neuroimaging Initiative.

J Clin Pharmacol. 2012 May;52(5):629-44. doi: 10.1177/0091270011405497. Epub 2011 Jun 9.

PMID:
21659625
[PubMed - indexed for MEDLINE]
9.

Broadening access to electronic healthcare databases.

Cepeda MS, Lobanov VS, Farnum M, Weinstein R, Gates P, Agrafiotis DK, Stang P, Berlin JA.

Nat Rev Drug Discov. 2010 Jan;9(1):84. doi: 10.1038/nrd2988-c1. No abstract available.

PMID:
20043030
[PubMed - indexed for MEDLINE]
10.

Advanced biological and chemical discovery (ABCD): centralizing discovery knowledge in an inherently decentralized world.

Agrafiotis DK, Alex S, Dai H, Derkinderen A, Farnum M, Gates P, Izrailev S, Jaeger EP, Konstant P, Leung A, Lobanov VS, Marichal P, Martin D, Rassokhin DN, Shemanarev M, Skalkin A, Stong J, Tabruyn T, Vermeiren M, Wan J, Xu XY, Yao X.

J Chem Inf Model. 2007 Nov-Dec;47(6):1999-2014. Epub 2007 Nov 1.

PMID:
17973472
[PubMed - indexed for MEDLINE]
11.

SAR maps: a new SAR visualization technique for medicinal chemists.

Agrafiotis DK, Shemanarev M, Connolly PJ, Farnum M, Lobanov VS.

J Med Chem. 2007 Nov 29;50(24):5926-37. Epub 2007 Oct 25.

PMID:
17958407
[PubMed - indexed for MEDLINE]
12.

Radial clustergrams: visualizing the aggregate properties of hierarchical clusters.

Agrafiotis DK, Bandyopadhyay D, Farnum M.

J Chem Inf Model. 2007 Jan-Feb;47(1):69-75.

PMID:
17238250
[PubMed - indexed for MEDLINE]
13.

Universal screening methods and applications of ThermoFluor.

Cummings MD, Farnum MA, Nelen MI.

J Biomol Screen. 2006 Oct;11(7):854-63. Epub 2006 Aug 30. Review.

PMID:
16943390
[PubMed - indexed for MEDLINE]
14.

Enzyme classification by ligand binding.

Izrailev S, Farnum MA.

Proteins. 2004 Dec 1;57(4):711-24.

PMID:
15476211
[PubMed - indexed for MEDLINE]
15.

Exploring the nonlinear geometry of protein homology.

Farnum MA, Xu H, Agrafiotis DK.

Protein Sci. 2003 Aug;12(8):1604-12.

PMID:
12876310
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Effect of glycerol on the interactions and solubility of bovine pancreatic trypsin inhibitor.

Farnum M, Zukoski C.

Biophys J. 1999 May;76(5):2716-26.

PMID:
10233086
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Structure and function of alternative proton-relay mutants of dihydrofolate reductase.

David CL, Howell EE, Farnum MF, Villafranca JE, Oatley SJ, Kraut J.

Biochemistry. 1992 Oct 13;31(40):9813-22.

PMID:
1356437
[PubMed - indexed for MEDLINE]
18.

Analysis of hydride transfer and cofactor fluorescence decay in mutants of dihydrofolate reductase: possible evidence for participation of enzyme molecular motions in catalysis.

Farnum MF, Magde D, Howell EE, Hirai JT, Warren MS, Grimsley JK, Kraut J.

Biochemistry. 1991 Dec 10;30(49):11567-79.

PMID:
1747376
[PubMed - indexed for MEDLINE]
19.

Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.

Warren MS, Brown KA, Farnum MF, Howell EE, Kraut J.

Biochemistry. 1991 Nov 19;30(46):11092-103.

PMID:
1932031
[PubMed - indexed for MEDLINE]
20.

Compound I radical in site-directed mutants of cytochrome c peroxidase as probed by electron paramagnetic resonance and electron-nuclear double resonance.

Fishel LA, Farnum MF, Mauro JM, Miller MA, Kraut J, Liu YJ, Tan XL, Scholes CP.

Biochemistry. 1991 Feb 19;30(7):1986-96.

PMID:
1847080
[PubMed - indexed for MEDLINE]

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