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Results: 1 to 20 of 45


Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast.

Frey JL, Li Z, Ellis JM, Zhang Q, Farber CR, Aja S, Wolfgang MJ, Clemens TL, Riddle RC.

Mol Cell Biol. 2015 Mar 23. pii: MCB.01343-14. [Epub ahead of print]


Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2.

Gularte-Mérida R, Farber CR, Verdugo RA, Islas Trejo A, Famula TR, Warden CH, Medrano JF.

BMC Genomics. 2015 Jan 23;16(1):16. [Epub ahead of print]


Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density.

Mesner LD, Ray B, Hsu YH, Manichaikul A, Lum E, Bryda EC, Rich SS, Rosen CJ, Criqui MH, Allison M, Budoff MJ, Clemens TL, Farber CR.

J Clin Invest. 2014 Jun;124(6):2736-49. doi: 10.1172/JCI73072. Epub 2014 May 1.


Glucagon regulates hepatic kisspeptin to impair insulin secretion.

Song WJ, Mondal P, Wolfe A, Alonso LC, Stamateris R, Ong BW, Lim OC, Yang KS, Radovick S, Novaira HJ, Farber EA, Farber CR, Turner SD, Hussain MA.

Cell Metab. 2014 Apr 1;19(4):667-81. doi: 10.1016/j.cmet.2014.03.005.


A novel IFITM5 mutation in severe atypical osteogenesis imperfecta type VI impairs osteoblast production of pigment epithelium-derived factor.

Farber CR, Reich A, Barnes AM, Becerra P, Rauch F, Cabral WA, Bae A, Quinlan A, Glorieux FH, Clemens TL, Marini JC.

J Bone Miner Res. 2014 Jun;29(6):1402-11.


Bioenergetics during calvarial osteoblast differentiation reflect strain differences in bone mass.

Guntur AR, Le PT, Farber CR, Rosen CJ.

Endocrinology. 2014 May;155(5):1589-95. doi: 10.1210/en.2013-1974. Epub 2014 Jan 17.


Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men.

Wang L, Lu W, Zhang L, Huang Y, Scheib R, Liu X, Myers L, Lu L, Farber CR, Liu G, Wang CY, Deng H, Williams RW, Wang Y, Gu W, Jiao Y.

PLoS One. 2014 Jan 8;9(1):e84485. doi: 10.1371/journal.pone.0084485. eCollection 2014.


MicroRNA-93 controls perfusion recovery after hindlimb ischemia by modulating expression of multiple genes in the cell cycle pathway.

Hazarika S, Farber CR, Dokun AO, Pitsillides AN, Wang T, Lye RJ, Annex BH.

Circulation. 2013 Apr 30;127(17):1818-28. doi: 10.1161/CIRCULATIONAHA.112.000860. Epub 2013 Apr 4.


Quantitative trait loci for bone mineral density and femoral morphology in an advanced intercross population of mice.

Leamy LJ, Kelly SA, Hua K, Farber CR, Pomp D.

Bone. 2013 Jul;55(1):222-9. doi: 10.1016/j.bone.2013.02.014. Epub 2013 Feb 26.


Systems-level analysis of genome-wide association data.

Farber CR.

G3 (Bethesda). 2013 Jan;3(1):119-29. doi: 10.1534/g3.112.004788. Epub 2013 Jan 1.


Systems genetic analysis of osteoblast-lineage cells.

Calabrese G, Bennett BJ, Orozco L, Kang HM, Eskin E, Dombret C, De Backer O, Lusis AJ, Farber CR.

PLoS Genet. 2012;8(12):e1003150. doi: 10.1371/journal.pgen.1003150. Epub 2012 Dec 27.


Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages.

Orozco LD, Bennett BJ, Farber CR, Ghazalpour A, Pan C, Che N, Wen P, Qi HX, Mutukulu A, Siemers N, Neuhaus I, Yordanova R, Gargalovic P, Pellegrini M, Kirchgessner T, Lusis AJ.

Cell. 2012 Oct 26;151(3):658-70. doi: 10.1016/j.cell.2012.08.043.


Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits.

Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, Jentsch JD, Kostem E, Kang HM, Kang EY, Joo JW, Korshunov VA, Laughlin RE, Martin LJ, Ohmen JD, Parks BW, Pellegrini M, Reue K, Smith DJ, Tetradis S, Wang J, Wang Y, Weiss JN, Kirchgessner T, Gargalovic PS, Eskin E, Lusis AJ, LeBoeuf RC.

Mamm Genome. 2012 Oct;23(9-10):680-92. doi: 10.1007/s00335-012-9411-5. Epub 2012 Aug 15. Review.


Systems genetics: a novel approach to dissect the genetic basis of osteoporosis.

Farber CR.

Curr Osteoporos Rep. 2012 Sep;10(3):228-35. doi: 10.1007/s11914-012-0112-5. Review.


Increasing association mapping power and resolution in mouse genetic studies through the use of meta-analysis for structured populations.

Furlotte NA, Kang EY, Van Nas A, Farber CR, Lusis AJ, Eskin E.

Genetics. 2012 Jul;191(3):959-67. doi: 10.1534/genetics.112.140277. Epub 2012 Apr 13.


Genome scans for transmission ratio distortion regions in mice.

Casellas J, Gularte RJ, Farber CR, Varona L, Mehrabian M, Schadt EE, Lusis AJ, Attie AD, Yandell BS, Medrano JF.

Genetics. 2012 May;191(1):247-59. doi: 10.1534/genetics.111.135988. Epub 2012 Feb 23.


Comparative analysis of proteome and transcriptome variation in mouse.

Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG 2nd, Pan C, Yordanova R, Neuhaus I, Tilford C, Siemers N, Gargalovic P, Eskin E, Kirchgessner T, Smith DJ, Smith RD, Lusis AJ.

PLoS Genet. 2011 Jun;7(6):e1001393. doi: 10.1371/journal.pgen.1001393. Epub 2011 Jun 9.


Hippocampal gene expression analysis highlights Ly6a/Sca-1 as candidate gene for previously mapped novelty induced behaviors in mice.

de Jong S, Kas MJ, Kiernan J, de Mooij-van Malsen AG, Oppelaar H, Janson E, Vukobradovic I, Farber CR, Stanford WL, Ophoff RA.

PLoS One. 2011;6(6):e20716. doi: 10.1371/journal.pone.0020716. Epub 2011 Jun 6.


Identification of quantitative trait loci influencing skeletal architecture in mice: emergence of Cdh11 as a primary candidate gene regulating femoral morphology.

Farber CR, Kelly SA, Baruch E, Yu D, Hua K, Nehrenberg DL, de Villena FP, Buus RJ, Garland T Jr, Pomp D.

J Bone Miner Res. 2011 Sep;26(9):2174-83. doi: 10.1002/jbmr.436.


Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis.

Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, Lusis AJ.

PLoS Genet. 2011 Apr;7(4):e1002038. doi: 10.1371/journal.pgen.1002038. Epub 2011 Apr 7.

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