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Results: 1 to 20 of 127

1.

Oxidation increases mucin polymer cross-links to stiffen airway mucus gels.

Yuan S, Hollinger M, Lachowicz-Scroggins ME, Kerr SC, Dunican EM, Daniel BM, Ghosh S, Erzurum SC, Willard B, Hazen SL, Huang X, Carrington SD, Oscarson S, Fahy JV.

Sci Transl Med. 2015 Feb 25;7(276):276ra27. doi: 10.1126/scitranslmed.3010525.

2.

Type 2 inflammation in asthma--present in most, absent in many.

Fahy JV.

Nat Rev Immunol. 2015 Jan;15(1):57-65. doi: 10.1038/nri3786. Review.

3.

A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.

Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff PG, Ansel KM.

Nat Immunol. 2014 Dec;15(12):1162-70. doi: 10.1038/ni.3026. Epub 2014 Nov 2.

PMID:
25362490
4.

Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma.

Greer AM, Matthay MA, Kukreja J, Bhakta NR, Nguyen CP, Wolters PJ, Woodruff PG, Fahy JV, Shin JS.

PLoS One. 2014 Jun 10;9(6):e99084. doi: 10.1371/journal.pone.0099084. eCollection 2014.

5.

Asthma: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.

Jackson DJ, Hartert TV, Martinez FD, Weiss ST, Fahy JV.

Ann Am Thorac Soc. 2014 Apr;11 Suppl 3:S139-45. doi: 10.1513/AnnalsATS.201312-448LD. Review.

6.

Intelectin-1 is a prominent protein constituent of pathologic mucus associated with eosinophilic airway inflammation in asthma.

Kerr SC, Carrington SD, Oscarson S, Gallagher ME, Solon M, Yuan S, Ahn JN, Dougherty RH, Finkbeiner WE, Peters MC, Fahy JV.

Am J Respir Crit Care Med. 2014 Apr 15;189(8):1005-7. doi: 10.1164/rccm.201312-2220LE. No abstract available.

7.

Asthma and the flu: a tricky two-step.

Locksley RM, Fahy JV.

Immunol Cell Biol. 2014 May-Jun;92(5):389-91. doi: 10.1038/icb.2014.24. Epub 2014 Apr 1. No abstract available.

8.

A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity.

Houser J, Komarek J, Kostlanova N, Cioci G, Varrot A, Kerr SC, Lahmann M, Balloy V, Fahy JV, Chignard M, Imberty A, Wimmerova M.

PLoS One. 2013 Dec 10;8(12):e83077. doi: 10.1371/journal.pone.0083077. eCollection 2013.

9.

Chair's summary: Mechanisms of relevance to clinical heterogeneity of asthma and chronic obstructive pulmonary disease.

Fahy JV.

Ann Am Thorac Soc. 2013 Dec;10 Suppl:S108. doi: 10.1513/AnnalsATS.201307-239AW. No abstract available.

PMID:
24313759
10.

Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma.

Peters MC, Mekonnen ZK, Yuan S, Bhakta NR, Woodruff PG, Fahy JV.

J Allergy Clin Immunol. 2014 Feb;133(2):388-94. doi: 10.1016/j.jaci.2013.07.036. Epub 2013 Sep 24.

11.

Type 2 immune responses in obese individuals with asthma.

Peters MC, Fahy JV.

Am J Respir Crit Care Med. 2013 Sep 15;188(6):633-4. doi: 10.1164/rccm.201307-1360ED. No abstract available.

PMID:
24032378
12.

A qPCR-based metric of Th2 airway inflammation in asthma.

Bhakta NR, Solberg OD, Nguyen CP, Nguyen CN, Arron JR, Fahy JV, Woodruff PG.

Clin Transl Allergy. 2013 Jul 17;3(1):24. doi: 10.1186/2045-7022-3-24.

13.

An integrated nano-scale approach to profile miRNAs in limited clinical samples.

Seumois G, Vijayanand P, Eisley CJ, Omran N, Kalinke L, North M, Ganesan AP, Simpson LJ, Hunkapiller N, Moltzahn F, Woodruff PG, Fahy JV, Erle DJ, Djukanovic R, Blelloch R, Ansel KM.

Am J Clin Exp Immunol. 2012 Nov 30;1(2):70-89.

14.

P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy.

Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA, Peters SP, Sheerar D, Shi L, Sutherland ER, Szefler SJ, Wechsler ME, Sorkness CA, Lemanske RF Jr; NHLBI Asthma Clinical Research Network Investigators.

Am J Respir Crit Care Med. 2013 Jan 1;187(1):28-33. doi: 10.1164/rccm.201204-0750OC. Epub 2012 Nov 9.

15.

Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction.

Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, Li M, Jan YN, Jan LY, Rock JR.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16354-9. doi: 10.1073/pnas.1214596109. Epub 2012 Sep 17.

16.

Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial.

Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Moore WC, Pascual R, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Boushey HA; Asthma Clinical Research Network of the National Heart, Lung, and Blood Institute.

JAMA. 2012 Sep 12;308(10):987-97. doi: 10.1001/2012.jama.10893.

17.

Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients.

Jia G, Erickson RW, Choy DF, Mosesova S, Wu LC, Solberg OD, Shikotra A, Carter R, Audusseau S, Hamid Q, Bradding P, Fahy JV, Woodruff PG, Harris JM, Arron JR; Bronchoscopic Exploratory Research Study of Biomarkers in Corticosteroid-refractory Asthma (BOBCAT) Study Group.

J Allergy Clin Immunol. 2012 Sep;130(3):647-654.e10. doi: 10.1016/j.jaci.2012.06.025. Epub 2012 Aug 1.

18.

Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics.

Diez D, Goto S, Fahy JV, Erle DJ, Woodruff PG, Wheelock ÅM, Wheelock CE.

BMC Med Genomics. 2012 Jun 19;5:27. doi: 10.1186/1755-8794-5-27.

19.

Cluster analysis of obesity and asthma phenotypes.

Sutherland ER, Goleva E, King TS, Lehman E, Stevens AD, Jackson LP, Stream AR, Fahy JV, Leung DY; Asthma Clinical Research Network.

PLoS One. 2012;7(5):e36631. doi: 10.1371/journal.pone.0036631. Epub 2012 May 11.

20.

Asthma outcomes: biomarkers.

Szefler SJ, Wenzel S, Brown R, Erzurum SC, Fahy JV, Hamilton RG, Hunt JF, Kita H, Liu AH, Panettieri RA Jr, Schleimer RP, Minnicozzi M.

J Allergy Clin Immunol. 2012 Mar;129(3 Suppl):S9-23. doi: 10.1016/j.jaci.2011.12.979. Review.

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