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Results: 1 to 20 of 33

1.

Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation.

Estève PO, Terragni J, Deepti K, Chin HG, Dai N, Espejo A, Corrêa IR Jr, Bedford MT, Pradhan S.

J Biol Chem. 2014 Mar 21;289(12):8277-87. doi: 10.1074/jbc.M113.525279. Epub 2014 Feb 3.

PMID:
24492612
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress.

Laget S, Miotto B, Chin HG, Estève PO, Roberts RJ, Pradhan S, Defossez PA.

Epigenetics. 2014 Apr;9(4):546-56. doi: 10.4161/epi.27695. Epub 2014 Jan 16.

PMID:
24434851
[PubMed - in process]
3.

PKC isoforms interact with and phosphorylate DNMT1.

Lavoie G, Estève PO, Laulan NB, Pradhan S, St-Pierre Y.

BMC Biol. 2011 May 27;9:31. doi: 10.1186/1741-7007-9-31.

PMID:
21619587
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes.

Kinney SM, Chin HG, Vaisvila R, Bitinaite J, Zheng Y, Estève PO, Feng S, Stroud H, Jacobsen SE, Pradhan S.

J Biol Chem. 2011 Jul 15;286(28):24685-93. doi: 10.1074/jbc.M110.217083. Epub 2011 May 24.

PMID:
21610077
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

5-Aza-2'-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression.

Couillard J, Estève PO, Pradhan S, St-Pierre Y.

Int J Cancer. 2011 Nov 1;129(9):2083-92. doi: 10.1002/ijc.25865. Epub 2011 Feb 26.

PMID:
21170958
[PubMed - indexed for MEDLINE]
6.

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.

Estève PO, Chang Y, Samaranayake M, Upadhyay AK, Horton JR, Feehery GR, Cheng X, Pradhan S.

Nat Struct Mol Biol. 2011 Jan;18(1):42-8. doi: 10.1038/nsmb.1939. Epub 2010 Dec 12.

PMID:
21151116
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

SET7/9 mediated methylation of non-histone proteins in mammalian cells.

Pradhan S, Chin HG, Estève PO, Jacobsen SE.

Epigenetics. 2009 Aug 16;4(6):383-7. Epub 2009 Aug 6. Review.

PMID:
19684477
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells.

Estève PO, Chin HG, Benner J, Feehery GR, Samaranayake M, Horwitz GA, Jacobsen SE, Pradhan S.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5076-81. doi: 10.1073/pnas.0810362106. Epub 2009 Mar 12.

PMID:
19282482
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells.

Kim JK, Estève PO, Jacobsen SE, Pradhan S.

Nucleic Acids Res. 2009 Feb;37(2):493-505. doi: 10.1093/nar/gkn961. Epub 2008 Dec 4.

PMID:
19056828
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

CXXC domain of human DNMT1 is essential for enzymatic activity.

Pradhan M, Estève PO, Chin HG, Samaranayke M, Kim GD, Pradhan S.

Biochemistry. 2008 Sep 23;47(38):10000-9. doi: 10.1021/bi8011725. Epub 2008 Aug 29.

PMID:
18754681
[PubMed - indexed for MEDLINE]
11.

Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation.

Ding N, Zhou H, Esteve PO, Chin HG, Kim S, Xu X, Joseph SM, Friez MJ, Schwartz CE, Pradhan S, Boyer TG.

Mol Cell. 2008 Aug 8;31(3):347-59. doi: 10.1016/j.molcel.2008.05.023.

PMID:
18691967
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Automethylation of G9a and its implication in wider substrate specificity and HP1 binding.

Chin HG, Estève PO, Pradhan M, Benner J, Patnaik D, Carey MF, Pradhan S.

Nucleic Acids Res. 2007;35(21):7313-23. Epub 2007 Oct 25.

PMID:
17962312
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

UHRF1 plays a role in maintaining DNA methylation in mammalian cells.

Bostick M, Kim JK, Estève PO, Clark A, Pradhan S, Jacobsen SE.

Science. 2007 Sep 21;317(5845):1760-4. Epub 2007 Aug 2.

PMID:
17673620
[PubMed - indexed for MEDLINE]
Free Article
14.

Functional cooperation between HP1 and DNMT1 mediates gene silencing.

Smallwood A, Estève PO, Pradhan S, Carey M.

Genes Dev. 2007 May 15;21(10):1169-78. Epub 2007 Apr 30.

PMID:
17470536
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells.

Estève PO, Chin HG, Pradhan S.

J Biol Chem. 2007 Jan 26;282(4):2615-25. Epub 2006 Nov 22.

PMID:
17124180
[PubMed - indexed for MEDLINE]
Free Article
16.

Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication.

Estève PO, Chin HG, Smallwood A, Feehery GR, Gangisetty O, Karpf AR, Carey MF, Pradhan S.

Genes Dev. 2006 Nov 15;20(22):3089-103. Epub 2006 Nov 3.

PMID:
17085482
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

DNA damage-induced down-regulation of human Cdc25C and Cdc2 is mediated by cooperation between p53 and maintenance DNA (cytosine-5) methyltransferase 1.

Le Gac G, Estève PO, Ferec C, Pradhan S.

J Biol Chem. 2006 Aug 25;281(34):24161-70. Epub 2006 Jun 28.

PMID:
16807237
[PubMed - indexed for MEDLINE]
Free Article
18.

Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis.

Chin HG, Patnaik D, Estève PO, Jacobsen SE, Pradhan S.

Biochemistry. 2006 Mar 14;45(10):3272-84.

PMID:
16519522
[PubMed - indexed for MEDLINE]
19.

Sequence specificity and role of proximal amino acids of the histone H3 tail on catalysis of murine G9A lysine 9 histone H3 methyltransferase.

Chin HG, Pradhan M, Estève PO, Patnaik D, Evans TC Jr, Pradhan S.

Biochemistry. 2005 Oct 4;44(39):12998-3006.

PMID:
16185068
[PubMed - indexed for MEDLINE]
20.

Functional analysis of the N- and C-terminus of mammalian G9a histone H3 methyltransferase.

Estève PO, Patnaik D, Chin HG, Benner J, Teitell MA, Pradhan S.

Nucleic Acids Res. 2005 Jun 6;33(10):3211-23. Print 2005.

PMID:
15939934
[PubMed - indexed for MEDLINE]
Free PMC Article

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