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Epihetacillin.
Johnson DA, Mania D, Panetta CA, Silvestri HH. Johnson DA, et al. Tetrahedron Lett. 1968 Feb;16:1903-5. doi: 10.1016/s0040-4039(01)99051-3. Tetrahedron Lett. 1968. PMID: 5645063 No abstract available.
Preparation of 6-epi-ampicillin and of 6-epi-alpha-hydroxybenzylpenicillin.
Roets E, Vlietinck A, Vanderhaeghe H. Roets E, et al. J Antibiot (Tokyo). 1977 Oct;30(10):847-55. doi: 10.7164/antibiotics.30.847. J Antibiot (Tokyo). 1977. PMID: 563392 Free article.
The preparation of 6-epi-ampicillin by hydrolysis of 6-epihetacillin is described. During this conversion, the formation of a diketopiperazine was also observed. ...
The preparation of 6-epi-ampicillin by hydrolysis of 6-epihetacillin is described. During this conversion, the formation of a diketop …
Hydrolysis and epimerization kinetics of hetacillin in aqueous solution.
Tsuji A, Itatani Y, Yamana T. Tsuji A, et al. J Pharm Sci. 1977 Jul;66(7):1004-9. doi: 10.1002/jps.2600660727. J Pharm Sci. 1977. PMID: 18591
Methods were developed for quantitating epimerization to epihetacillin and hydrolysis to ampicillin in the alkaline degradation of hetacillin, and both rates in deuterium oxide at 35 degrees and in water at various temperatures were determined. ...
Methods were developed for quantitating epimerization to epihetacillin and hydrolysis to ampicillin in the alkaline degradation of he …