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Items: 9

1.

HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.

Ombrello MJ, Remmers EF, Tachmazidou I, Grom A, Foell D, Haas JP, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Mellins ED, Ilowite NT, Russo R, Len C, Hilario MO, Oliveira S, Yeung RS, Rosenberg A, Wedderburn LR, Anton J, Schwarz T, Hinks A, Bilginer Y, Park J, Cobb J, Satorius CL, Han B, Baskin E, Signa S, Duerr RH, Achkar JP, Kamboh MI, Kaufman KM, Kottyan LC, Pinto D, Scherer SW, Alarcón-Riquelme ME, Docampo E, Estivill X, Gül A; British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group; Childhood Arthritis Prospective Study (CAPS) Group; Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators; Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group; Biologically Based Outcome Predictors in JIA (BBOP) Group, de Bakker PI, Raychaudhuri S, Langefeld CD, Thompson S, Zeggini E, Thomson W, Kastner DL, Woo P; International Childhood Arthritis Genetics (INCHARGE) Consortium.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15970-5. doi: 10.1073/pnas.1520779112. Epub 2015 Nov 23.

2.

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.

Cobb J, Cule E, Moncrieffe H, Hinks A, Ursu S, Patrick F, Kassoumeri L, Flynn E, Bulatović M, Wulffraat N, van Zelst B, de Jonge R, Bohm M, Dolezalova P, Hirani S, Newman S, Whitworth P, Southwood TR, De Iorio M; Childhood Arthritis Response to Medication Study (CHARMS); Childhood Arthritis Prospective Study (CAPS); BSPAR study group, Wedderburn LR, Thomson W.

Pharmacogenomics J. 2014 Aug;14(4):356-64. doi: 10.1038/tpj.2014.3. Epub 2014 Apr 8.

3.

Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA).

Omoyinmi E, Forabosco P, Hamaoui R, Bryant A, Hinks A, Ursu S; Childhood Arthritis Prospective Study (CAPS); BSPAR study group; Childhood Arthritis Response to Medication Study (CHARMS), Wedderburn LR, Thomson W, Lewis CM, Woo P.

PLoS One. 2012;7(10):e47673. doi: 10.1371/journal.pone.0047673. Epub 2012 Oct 18.

4.

Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.

Hinks A, Cobb J, Sudman M, Eyre S, Martin P, Flynn E, Packham J; Childhood Arthritis Prospective Study (CAPS); UK RA Genetics (UKRAG) Consortium; British Society of Paediatric and Adolescent Rheumatology (BSPAR) Study Group, Barton A, Worthington J, Langefeld CD, Glass DN, Thompson SD, Thomson W.

Ann Rheum Dis. 2012 Jul;71(7):1117-21. doi: 10.1136/annrheumdis-2011-200814. Epub 2012 Jan 31.

5.

Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis.

Hinks A, Martin P, Flynn E, Eyre S, Packham J; Childhood Arthritis Prospective Study-CAPS; BSPAR Study Group, Barton A, Worthington J, Thomson W.

Arthritis Res Ther. 2011 Jan 31;13(1):R12. doi: 10.1186/ar3235.

6.

Association of the CCR5 gene with juvenile idiopathic arthritis.

Hinks A, Martin P, Flynn E, Eyre S, Packham J; Childhood Arthritis Prospective Study (CAPS), UKRAG Consortium, BSPAR Study Group, Barton A, Worthington J, Thomson W.

Genes Immun. 2010 Oct;11(7):584-9. doi: 10.1038/gene.2010.25. Epub 2010 May 13.

7.

Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis.

Hinks A, Eyre S, Ke X, Barton A, Martin P, Flynn E, Packham J, Worthington J; Childhood Arthritis Prospective Study; UKRAG Consortium; BSPAR Study Group, Thomson W.

Genes Immun. 2010 Mar;11(2):194-8. doi: 10.1038/gene.2009.105. Epub 2010 Jan 14.

8.

Functional defecation disorder as a clinical subgroup of chronic constipation: analysis of symptoms and physiological parameters.

Eltringham MT, Khan U, Bain IM, Wooff DA, Mackie A, Jefferson E, Yiannakou Y.

Scand J Gastroenterol. 2008 Mar;43(3):262-9. doi: 10.1080/00365520701686210.

PMID:
18266173
9.

Delay in access to appropriate care for children presenting with musculoskeletal symptoms and ultimately diagnosed with juvenile idiopathic arthritis.

Foster HE, Eltringham MS, Kay LJ, Friswell M, Abinun M, Myers A.

Arthritis Rheum. 2007 Aug 15;57(6):921-7.

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