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Items: 1 to 20 of 114

1.

MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria.

Dalla Rosa I, Cámara Y, Durigon R, Moss CF, Vidoni S, Akman G, Hunt L, Johnson MA, Grocott S, Wang L, Thorburn DR, Hirano M, Poulton J, Taylor RW, Elgar G, Martí R, Voshol P, Holt IJ, Spinazzola A.

PLoS Genet. 2016 Jan 13;12(1):e1005779. doi: 10.1371/journal.pgen.1005779. eCollection 2016 Jan.

2.

Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5.

Hunt LE, Noyvert B, Bhaw-Rosun L, Sesay AK, Paternoster L, Nohr EA, Davey Smith G, Tommerup N, Sørensen TI, Elgar G.

Genome Med. 2015 Dec 7;7:126. doi: 10.1186/s13073-015-0250-3.

3.

Evolution of lineage-specific functions in ancient cis-regulatory modules.

Pauls S, Goode DK, Petrone L, Oliveri P, Elgar G.

Open Biol. 2015 Nov;5(11). pii: 150079. doi: 10.1098/rsob.150079.

4.

Identification and functional characterization of novel transcriptional enhancers involved in regulating human GLI3 expression during early development.

Anwar S, Minhas R, Ali S, Lambert N, Kawakami Y, Elgar G, Azam SS, Abbasi AA.

Dev Growth Differ. 2015 Oct;57(8):570-80. doi: 10.1111/dgd.12239. Epub 2015 Oct 14.

5.

A Simple Predictive Enhancer Syntax for Hindbrain Patterning Is Conserved in Vertebrate Genomes.

Grice J, Noyvert B, Doglio L, Elgar G.

PLoS One. 2015 Jul 1;10(7):e0130413. doi: 10.1371/journal.pone.0130413. eCollection 2015.

6.

Cis-regulatory control of human GLI2 expression in the developing neural tube and limb bud.

Minhas R, Pauls S, Ali S, Doglio L, Khan MR, Elgar G, Abbasi AA.

Dev Dyn. 2015 May;244(5):681-92. doi: 10.1002/dvdy.24266. Epub 2015 Apr 8.

7.

Purifying selection in deeply conserved human enhancers is more consistent than in coding sequences.

De Silva DR, Nichols R, Elgar G.

PLoS One. 2014 Jul 25;9(7):e103357. doi: 10.1371/journal.pone.0103357. eCollection 2014.

8.

Dissection of a Ciona regulatory element reveals complexity of cross-species enhancer activity.

Chen WC, Pauls S, Bacha J, Elgar G, Loose M, Shimeld SM.

Dev Biol. 2014 Jun 15;390(2):261-72. doi: 10.1016/j.ydbio.2014.03.013. Epub 2014 Mar 28.

9.

A reporter assay in lamprey embryos reveals both functional conservation and elaboration of vertebrate enhancers.

Parker HJ, Sauka-Spengler T, Bronner M, Elgar G.

PLoS One. 2014 Jan 9;9(1):e85492. doi: 10.1371/journal.pone.0085492. eCollection 2014.

10.

Parallel evolution of chordate cis-regulatory code for development.

Doglio L, Goode DK, Pelleri MC, Pauls S, Frabetti F, Shimeld SM, Vavouri T, Elgar G.

PLoS Genet. 2013 Nov;9(11):e1003904. doi: 10.1371/journal.pgen.1003904. Epub 2013 Nov 21. Erratum in: PLoS Genet. 2013 Nov;9(11). doi:10.1371/annotation/1fc82a4b-f9ea-461a-8987-1152078688e4.

11.

Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution.

Smith JJ, Kuraku S, Holt C, Sauka-Spengler T, Jiang N, Campbell MS, Yandell MD, Manousaki T, Meyer A, Bloom OE, Morgan JR, Buxbaum JD, Sachidanandam R, Sims C, Garruss AS, Cook M, Krumlauf R, Wiedemann LM, Sower SA, Decatur WA, Hall JA, Amemiya CT, Saha NR, Buckley KM, Rast JP, Das S, Hirano M, McCurley N, Guo P, Rohner N, Tabin CJ, Piccinelli P, Elgar G, Ruffier M, Aken BL, Searle SM, Muffato M, Pignatelli M, Herrero J, Jones M, Brown CT, Chung-Davidson YW, Nanlohy KG, Libants SV, Yeh CY, McCauley DW, Langeland JA, Pancer Z, Fritzsch B, de Jong PJ, Zhu B, Fulton LL, Theising B, Flicek P, Bronner ME, Warren WC, Clifton SW, Wilson RK, Li W.

Nat Genet. 2013 Apr;45(4):415-21, 421e1-2. doi: 10.1038/ng.2568. Epub 2013 Feb 24.

12.

Capturing the regulatory interactions of eukaryote genomes.

Goode DK, Elgar G.

Brief Funct Genomics. 2013 Mar;12(2):142-60. doi: 10.1093/bfgp/els041. Epub 2012 Oct 30. Review.

PMID:
23117864
13.

Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation.

Grant J, Mahadevaiah SK, Khil P, Sangrithi MN, Royo H, Duckworth J, McCarrey JR, VandeBerg JL, Renfree MB, Taylor W, Elgar G, Camerini-Otero RD, Gilchrist MJ, Turner JM.

Nature. 2012 Jul 12;487(7406):254-8. doi: 10.1038/nature11171.

14.

Lens development depends on a pair of highly conserved Sox21 regulatory elements.

Pauls S, Smith SF, Elgar G.

Dev Biol. 2012 May 1;365(1):310-8. doi: 10.1016/j.ydbio.2012.02.025. Epub 2012 Feb 24.

15.

Ancient Pbx-Hox signatures define hundreds of vertebrate developmental enhancers.

Parker HJ, Piccinelli P, Sauka-Spengler T, Bronner M, Elgar G.

BMC Genomics. 2011 Dec 30;12:637. doi: 10.1186/1471-2164-12-637.

16.

Stops making sense: translational trade-offs and stop codon reassignment.

Johnson LJ, Cotton JA, Lichtenstein CP, Elgar GS, Nichols RA, Polly PD, Le Comber SC.

BMC Evol Biol. 2011 Jul 29;11:227. doi: 10.1186/1471-2148-11-227.

17.

Functional analysis of conserved non-coding regions around the short stature hox gene (shox) in whole zebrafish embryos.

Kenyon EJ, McEwen GK, Callaway H, Elgar G.

PLoS One. 2011;6(6):e21498. doi: 10.1371/journal.pone.0021498. Epub 2011 Jun 24.

18.

Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events.

Goode DK, Callaway HA, Cerda GA, Lewis KE, Elgar G.

Development. 2011 Mar;138(5):879-84. doi: 10.1242/dev.055996. Epub 2011 Jan 19.

19.

Early evolution of conserved regulatory sequences associated with development in vertebrates.

McEwen GK, Goode DK, Parker HJ, Woolfe A, Callaway H, Elgar G.

PLoS Genet. 2009 Dec;5(12):e1000762. doi: 10.1371/journal.pgen.1000762. Epub 2009 Dec 11.

20.

The PAX258 gene subfamily: a comparative perspective.

Goode DK, Elgar G.

Dev Dyn. 2009 Dec;238(12):2951-74. doi: 10.1002/dvdy.22146. Review.

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