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Results: 1 to 20 of 108

1.

Purifying selection in deeply conserved human enhancers is more consistent than in coding sequences.

De Silva DR, Nichols R, Elgar G.

PLoS One. 2014 Jul 25;9(7):e103357. doi: 10.1371/journal.pone.0103357. eCollection 2014.

PMID:
25062004
[PubMed - in process]
Free Article
2.

Dissection of a Ciona regulatory element reveals complexity of cross-species enhancer activity.

Chen WC, Pauls S, Bacha J, Elgar G, Loose M, Shimeld SM.

Dev Biol. 2014 Jun 15;390(2):261-72. doi: 10.1016/j.ydbio.2014.03.013. Epub 2014 Mar 28.

PMID:
24680932
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A reporter assay in lamprey embryos reveals both functional conservation and elaboration of vertebrate enhancers.

Parker HJ, Sauka-Spengler T, Bronner M, Elgar G.

PLoS One. 2014 Jan 9;9(1):e85492. doi: 10.1371/journal.pone.0085492. eCollection 2014.

PMID:
24416417
[PubMed - in process]
Free PMC Article
4.

Parallel evolution of chordate cis-regulatory code for development.

Doglio L, Goode DK, Pelleri MC, Pauls S, Frabetti F, Shimeld SM, Vavouri T, Elgar G.

PLoS Genet. 2013 Nov;9(11):e1003904. doi: 10.1371/journal.pgen.1003904. Epub 2013 Nov 21. Erratum in: PLoS Genet. 2013 Nov;9(11). doi:10.1371/annotation/1fc82a4b-f9ea-461a-8987-1152078688e4.

PMID:
24282393
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution.

Smith JJ, Kuraku S, Holt C, Sauka-Spengler T, Jiang N, Campbell MS, Yandell MD, Manousaki T, Meyer A, Bloom OE, Morgan JR, Buxbaum JD, Sachidanandam R, Sims C, Garruss AS, Cook M, Krumlauf R, Wiedemann LM, Sower SA, Decatur WA, Hall JA, Amemiya CT, Saha NR, Buckley KM, Rast JP, Das S, Hirano M, McCurley N, Guo P, Rohner N, Tabin CJ, Piccinelli P, Elgar G, Ruffier M, Aken BL, Searle SM, Muffato M, Pignatelli M, Herrero J, Jones M, Brown CT, Chung-Davidson YW, Nanlohy KG, Libants SV, Yeh CY, McCauley DW, Langeland JA, Pancer Z, Fritzsch B, de Jong PJ, Zhu B, Fulton LL, Theising B, Flicek P, Bronner ME, Warren WC, Clifton SW, Wilson RK, Li W.

Nat Genet. 2013 Apr;45(4):415-21, 421e1-2. doi: 10.1038/ng.2568. Epub 2013 Feb 24.

PMID:
23435085
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Capturing the regulatory interactions of eukaryote genomes.

Goode DK, Elgar G.

Brief Funct Genomics. 2013 Mar;12(2):142-60. doi: 10.1093/bfgp/els041. Epub 2012 Oct 30. Review.

PMID:
23117864
[PubMed - indexed for MEDLINE]
7.

Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation.

Grant J, Mahadevaiah SK, Khil P, Sangrithi MN, Royo H, Duckworth J, McCarrey JR, VandeBerg JL, Renfree MB, Taylor W, Elgar G, Camerini-Otero RD, Gilchrist MJ, Turner JM.

Nature. 2012 Jul 12;487(7406):254-8. doi: 10.1038/nature11171.

PMID:
22722828
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Lens development depends on a pair of highly conserved Sox21 regulatory elements.

Pauls S, Smith SF, Elgar G.

Dev Biol. 2012 May 1;365(1):310-8. doi: 10.1016/j.ydbio.2012.02.025. Epub 2012 Feb 24.

PMID:
22387845
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Ancient Pbx-Hox signatures define hundreds of vertebrate developmental enhancers.

Parker HJ, Piccinelli P, Sauka-Spengler T, Bronner M, Elgar G.

BMC Genomics. 2011 Dec 30;12:637. doi: 10.1186/1471-2164-12-637.

PMID:
22208168
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Stops making sense: translational trade-offs and stop codon reassignment.

Johnson LJ, Cotton JA, Lichtenstein CP, Elgar GS, Nichols RA, Polly PD, Le Comber SC.

BMC Evol Biol. 2011 Jul 29;11:227. doi: 10.1186/1471-2148-11-227.

PMID:
21801361
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Functional analysis of conserved non-coding regions around the short stature hox gene (shox) in whole zebrafish embryos.

Kenyon EJ, McEwen GK, Callaway H, Elgar G.

PLoS One. 2011;6(6):e21498. doi: 10.1371/journal.pone.0021498. Epub 2011 Jun 24.

PMID:
21731768
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events.

Goode DK, Callaway HA, Cerda GA, Lewis KE, Elgar G.

Development. 2011 Mar;138(5):879-84. doi: 10.1242/dev.055996. Epub 2011 Jan 19.

PMID:
21247963
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Early evolution of conserved regulatory sequences associated with development in vertebrates.

McEwen GK, Goode DK, Parker HJ, Woolfe A, Callaway H, Elgar G.

PLoS Genet. 2009 Dec;5(12):e1000762. doi: 10.1371/journal.pgen.1000762. Epub 2009 Dec 11.

PMID:
20011110
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The PAX258 gene subfamily: a comparative perspective.

Goode DK, Elgar G.

Dev Dyn. 2009 Dec;238(12):2951-74. doi: 10.1002/dvdy.22146. Review.

PMID:
19924770
[PubMed - indexed for MEDLINE]
Free Article
15.

Pan-vertebrate conserved non-coding sequences associated with developmental regulation.

Elgar G.

Brief Funct Genomic Proteomic. 2009 Jul;8(4):256-65. doi: 10.1093/bfgp/elp033. Review.

PMID:
19752044
[PubMed - indexed for MEDLINE]
Free Article
16.

SAND, a new protein family: from nucleic acid to protein structure and function prediction.

Cottage A, Edwards YJ, Elgar G.

Comp Funct Genomics. 2001;2(4):226-35. doi: 10.1002/cfg.93.

PMID:
18628914
[PubMed]
Free PMC Article
17.

What is systems biology?

Elgar G.

Brief Funct Genomic Proteomic. 2008 Jul;7(4):237-8. doi: 10.1093/bfgp/eln036. Epub 2008 Jul 11. No abstract available.

PMID:
18621799
[PubMed - indexed for MEDLINE]
Free Article
18.

Tuning in to the signals: noncoding sequence conservation in vertebrate genomes.

Elgar G, Vavouri T.

Trends Genet. 2008 Jul;24(7):344-52. doi: 10.1016/j.tig.2008.04.005. Epub 2008 May 29. Review.

PMID:
18514361
[PubMed - indexed for MEDLINE]
19.

Organization of conserved elements near key developmental regulators in vertebrate genomes.

Woolfe A, Elgar G.

Adv Genet. 2008;61:307-38. doi: 10.1016/S0065-2660(07)00012-0. Review.

PMID:
18282512
[PubMed - indexed for MEDLINE]
20.

Persistence of duplicated PAC1 receptors in the teleost, Sparus auratus.

Cardoso JC, de Vet EC, Louro B, Elgar G, Clark MS, Power DM.

BMC Evol Biol. 2007 Nov 12;7:221.

PMID:
17997850
[PubMed - indexed for MEDLINE]
Free PMC Article

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