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Results: 1 to 20 of 69

1.

Cancer systems biology: embracing complexity to develop better anticancer therapeutic strategies.

Du W, Elemento O.

Oncogene. 2014 Sep 15. doi: 10.1038/onc.2014.291. [Epub ahead of print] Review.

PMID:
25220419
[PubMed - as supplied by publisher]
2.

Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation.

Popovic R, Martinez-Garcia E, Giannopoulou EG, Zhang Q, Zhang Q, Ezponda T, Shah MY, Zheng Y, Will CM, Small EC, Hua Y, Bulic M, Jiang Y, Carrara M, Calogero RA, Kath WL, Kelleher NL, Wang JP, Elemento O, Licht JD.

PLoS Genet. 2014 Sep 4;10(9):e1004566. doi: 10.1371/journal.pgen.1004566. eCollection 2014 Sep.

PMID:
25188243
[PubMed - in process]
Free PMC Article
3.

Tracing the roots of cancer evolution.

Jiang Y, Elemento O.

Cancer Discov. 2014 Sep;4(9):995-7. doi: 10.1158/2159-8290.CD-14-0743.

PMID:
25185189
[PubMed - in process]
4.

Deep-sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas.

Jiang Y, Redmond D, Nie K, Eng KW, Clozel T, Martin P, Tan L, Melnick AM, Tam W, Elemento O.

Genome Biol. 2014 Aug 15;15(8):432. [Epub ahead of print]

PMID:
25123191
[PubMed - as supplied by publisher]
Free PMC Article
5.

Cell-Cycle Reprogramming for PI3K Inhibition Overrides a Relapse-Specific C481S BTK Mutation Revealed by Longitudinal Functional Genomics in Mantle Cell Lymphoma.

Chiron D, Di Liberto M, Martin P, Huang X, Sharman J, Blecua P, Mathew S, Vijay P, Eng K, Ali S, Johnson A, Chang B, Ely S, Elemento O, Mason CE, Leonard JP, Chen-Kiang S.

Cancer Discov. 2014 Sep;4(9):1022-35. doi: 10.1158/2159-8290.CD-14-0098. Epub 2014 Jul 31.

PMID:
25082755
[PubMed - in process]
6.

Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.

Sandler VM, Lis R, Liu Y, Kedem A, James D, Elemento O, Butler JM, Scandura JM, Rafii S.

Nature. 2014 Jul 17;511(7509):312-8. doi: 10.1038/nature13547. Epub 2014 Jul 2.

PMID:
25030167
[PubMed - indexed for MEDLINE]
7.

Impact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib.

de Martino M, Zhuang D, Klatte T, Rieken M, Rouprêt M, Xylinas E, Clozel T, Krzywinski M, Elemento O, Shariat SF.

Cancer Biol Ther. 2014 Sep 1;15(9):1239-47. doi: 10.4161/cbt.29687. Epub 2014 Jul 14.

PMID:
24971884
[PubMed - in process]
8.

DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets.

Kasap C, Elemento O, Kapoor TM.

Nat Chem Biol. 2014 Aug;10(8):626-8. doi: 10.1038/nchembio.1551. Epub 2014 Jun 15.

PMID:
24929528
[PubMed - in process]
9.

Silencing of UCHL1 by CpG Promoter Hyper-methylation is Associated with Metastatic Gastroenteropancreatic Well-Differentiated Neuroendocrine (Carcinoid) Tumors.

Kleiman DA, Beninato T, Sultan S, Crowley MJ, Finnerty B, Kumar R, Panarelli NC, Liu YF, Lieberman MD, Seandel M, Evans T, Elemento O, Zarnegar R, Fahey TJ 3rd.

Ann Surg Oncol. 2014 May 23. [Epub ahead of print]

PMID:
24854489
[PubMed - as supplied by publisher]
10.

Histone variant H3.3 is an essential maternal factor for oocyte reprogramming.

Wen D, Banaszynski LA, Liu Y, Geng F, Noh KM, Xiang J, Elemento O, Rosenwaks Z, Allis CD, Rafii S.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7325-30. doi: 10.1073/pnas.1406389111. Epub 2014 May 5.

PMID:
24799717
[PubMed - indexed for MEDLINE]
11.

Characterization of the human cumulus cell transcriptome during final follicular maturation and ovulation.

Yerushalmi GM, Salmon-Divon M, Yung Y, Maman E, Kedem A, Ophir L, Elemento O, Coticchio G, Dal Canto M, Mignini Renzinu M, Fadini R, Hourvitz A.

Mol Hum Reprod. 2014 Aug;20(8):719-35. doi: 10.1093/molehr/gau031. Epub 2014 Apr 25.

PMID:
24770949
[PubMed - in process]
12.

Double-stranded DNA in exosomes: a novel biomarker in cancer detection.

Thakur BK, Zhang H, Becker A, Matei I, Huang Y, Costa-Silva B, Zheng Y, Hoshino A, Brazier H, Xiang J, Williams C, Rodriguez-Barrueco R, Silva JM, Zhang W, Hearn S, Elemento O, Paknejad N, Manova-Todorova K, Welte K, Bromberg J, Peinado H, Lyden D.

Cell Res. 2014 Jun;24(6):766-9. doi: 10.1038/cr.2014.44. Epub 2014 Apr 8. No abstract available.

PMID:
24710597
[PubMed - in process]
Free PMC Article
13.

The transcriptional modulator BCL6 as a molecular target for breast cancer therapy.

Walker SR, Liu S, Xiang M, Nicolais M, Hatzi K, Giannopoulou E, Elemento O, Cerchietti L, Melnick A, Frank DA.

Oncogene. 2014 Mar 24. doi: 10.1038/onc.2014.61. [Epub ahead of print]

PMID:
24662818
[PubMed - as supplied by publisher]
14.

Molecular diagnosis of autosomal dominant polycystic kidney disease using next-generation sequencing.

Tan AY, Michaeel A, Liu G, Elemento O, Blumenfeld J, Donahue S, Parker T, Levine D, Rennert H.

J Mol Diagn. 2014 Mar;16(2):216-28. doi: 10.1016/j.jmoldx.2013.10.005. Epub 2013 Dec 27.

PMID:
24374109
[PubMed - in process]
15.

Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis.

Rath P, Huang C, Wang T, Wang T, Li H, Prados-Rosales R, Elemento O, Casadevall A, Nathan CF.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4790-7. doi: 10.1073/pnas.1320118110. Epub 2013 Nov 18.

PMID:
24248369
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

EZH2 mutations are frequent and represent an early event in follicular lymphoma.

Bödör C, Grossmann V, Popov N, Okosun J, O'Riain C, Tan K, Marzec J, Araf S, Wang J, Lee AM, Clear A, Montoto S, Matthews J, Iqbal S, Rajnai H, Rosenwald A, Ott G, Campo E, Rimsza LM, Smeland EB, Chan WC, Braziel RM, Staudt LM, Wright G, Lister TA, Elemento O, Hills R, Gribben JG, Chelala C, Matolcsy A, Kohlmann A, Haferlach T, Gascoyne RD, Fitzgibbon J.

Blood. 2013 Oct 31;122(18):3165-8. doi: 10.1182/blood-2013-04-496893. Epub 2013 Sep 19.

PMID:
24052547
[PubMed - indexed for MEDLINE]
17.

Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling.

Qiao Y, Giannopoulou EG, Chan CH, Park SH, Gong S, Chen J, Hu X, Elemento O, Ivashkiv LB.

Immunity. 2013 Sep 19;39(3):454-69. doi: 10.1016/j.immuni.2013.08.009. Epub 2013 Sep 5.

PMID:
24012417
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells.

Israely E, Ginsberg M, Nolan D, Ding BS, James D, Elemento O, Rafii S, Rabbany SY.

Stem Cells. 2014 Jan;32(1):177-90. doi: 10.1002/stem.1521.

PMID:
23963623
[PubMed - in process]
19.

A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.

Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM, Kormaksson M, MacKerell AD Jr, Xue F, Mason CE, Hiebert SW, Prive GG, Cerchietti L, Bardwell VJ, Elemento O, Melnick A.

Cell Rep. 2013 Aug 15;4(3):578-88. doi: 10.1016/j.celrep.2013.06.016. Epub 2013 Aug 1.

PMID:
23911289
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration.

Nolan DJ, Ginsberg M, Israely E, Palikuqi B, Poulos MG, James D, Ding BS, Schachterle W, Liu Y, Rosenwaks Z, Butler JM, Xiang J, Rafii A, Shido K, Rabbany SY, Elemento O, Rafii S.

Dev Cell. 2013 Jul 29;26(2):204-19. doi: 10.1016/j.devcel.2013.06.017. Epub 2013 Jul 18.

PMID:
23871589
[PubMed - indexed for MEDLINE]
Free PMC Article

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