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Calreticulin, a therapeutic target?

Eggleton P, Bremer E, Dudek E, Michalak M.

Expert Opin Ther Targets. 2016 Mar 25:1-11. [Epub ahead of print]


Editorial: Endoplasmic Reticulum and Its Role in Tumor Immunity.

Eggleton P, Michalak M, Bremer E.

Front Oncol. 2015 Nov 17;5:252. doi: 10.3389/fonc.2015.00252. eCollection 2015. No abstract available.


Unfolding the complexities of ER chaperones in health and disease: report on the 11th international calreticulin workshop.

Gold L, Williams D, Groenendyk J, Michalak M, Eggleton P.

Cell Stress Chaperones. 2015 Nov;20(6):875-83. doi: 10.1007/s12192-015-0638-4. Epub 2015 Sep 22.


CD20+inflammatory T-cells are present in blood and brain of multiple sclerosis patients and can be selectively targeted for apoptotic elimination.

Holley JE, Bremer E, Kendall AC, de Bruyn M, Helfrich W, Tarr JM, Newcombe J, Gutowski NJ, Eggleton P.

Mult Scler Relat Disord. 2014 Sep;3(5):650-8. doi: 10.1016/j.msard.2014.06.001. Epub 2014 Jun 12.


Increased disease activity, severity and autoantibody positivity in rheumatoid arthritis patients with co-existent bronchiectasis.

Perry E, Eggleton P, De Soyza A, Hutchinson D, Kelly C.

Int J Rheum Dis. 2015 Jul 22. doi: 10.1111/1756-185X.12702. [Epub ahead of print]


CD20+ T cells have a predominantly Tc1 effector memory phenotype and are expanded in the ascites of patients with ovarian cancer.

de Bruyn M, Wiersma VR, Wouters MC, Samplonius DF, Klip HG, Helfrich W, Nijman HW, Eggleton P, Bremer E.

Oncoimmunology. 2015 Mar 19;4(4):e999536. eCollection 2015 Apr.


The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.

Wiersma VR, de Bruyn M, Wei Y, van Ginkel RJ, Hirashima M, Niki T, Nishi N, Zhou J, Pouwels SD, Samplonius DF, Nijman HW, Eggleton P, Helfrich W, Bremer E.

Autophagy. 2015;11(8):1373-88. doi: 10.1080/15548627.2015.1063767.


Bronchiectasis is a Model for Chronic Bacterial Infection Inducing Autoimmunity in Rheumatoid Arthritis.

Quirke AM, Perry E, Cartwright A, Kelly C, De Soyza A, Eggleton P, Hutchinson D, Venables PJ.

Arthritis Rheumatol. 2015 Sep;67(9):2335-42. doi: 10.1002/art.39226.


Logging cuts the functional importance of invertebrates in tropical rainforest.

Ewers RM, Boyle MJ, Gleave RA, Plowman NS, Benedick S, Bernard H, Bishop TR, Bakhtiar EY, Chey VK, Chung AY, Davies RG, Edwards DP, Eggleton P, Fayle TM, Hardwick SR, Homathevi R, Kitching RL, Khoo MS, Luke SH, March JJ, Nilus R, Pfeifer M, Rao SV, Sharp AC, Snaddon JL, Stork NE, Struebig MJ, Wearn OR, Yusah KM, Turner EC.

Nat Commun. 2015 Apr 13;6:6836. doi: 10.1038/ncomms7836.


Detection of mitochondrial COII DNA sequences in ant guts as a method for assessing termite predation by ants.

Fayle TM, Scholtz O, Dumbrell AJ, Russell S, Segar ST, Eggleton P.

PLoS One. 2015 Apr 8;10(4):e0122533. doi: 10.1371/journal.pone.0122533. eCollection 2015.


The ever-expanding immunomodulatory role of calreticulin in cancer immunity.

de Bruyn M, Wiersma VR, Helfrich W, Eggleton P, Bremer E.

Front Oncol. 2015 Feb 20;5:35. doi: 10.3389/fonc.2015.00035. eCollection 2015. Review.


Mechanisms of Translocation of ER Chaperones to the Cell Surface and Immunomodulatory Roles in Cancer and Autoimmunity.

Wiersma VR, Michalak M, Abdullah TM, Bremer E, Eggleton P.

Front Oncol. 2015 Jan 29;5:7. doi: 10.3389/fonc.2015.00007. eCollection 2015. Review.


Experimentally testing and assessing the predictive power of species assembly rules for tropical canopy ants.

Fayle TM, Eggleton P, Manica A, Yusah KM, Foster WA.

Ecol Lett. 2015 Mar;18(3):254-62. doi: 10.1111/ele.12403. Epub 2015 Jan 27.


Identifying possible sister groups of Cryptocercidae+Isoptera: a combined molecular and morphological phylogeny of Dictyoptera.

Djernæs M, Klass KD, Eggleton P.

Mol Phylogenet Evol. 2015 Mar;84:284-303. doi: 10.1016/j.ympev.2014.08.019. Epub 2014 Sep 4.


RA autoantibodies as predictors of rheumatoid arthritis in non-cystic fibrosis bronchiectasis patients.

Perry E, Stenton C, Kelly C, Eggleton P, Hutchinson D, De Soyza A.

Eur Respir J. 2014 Oct;44(4):1082-5. doi: 10.1183/09031936.00064014. Epub 2014 Jun 25. No abstract available.


Autoantibodies against C1q as a Diagnostic Measure of Lupus Nephritis: Systematic Review and Meta-analysis.

Eggleton P, Ukoumunne OC, Cottrell I, Khan A, Maqsood S, Thornes J, Perry E, Isenberg D.

J Clin Cell Immunol. 2014 Apr 22;5(2):210.


The lung in ACPA-positive rheumatoid arthritis: an initiating site of injury?

Perry E, Kelly C, Eggleton P, De Soyza A, Hutchinson D.

Rheumatology (Oxford). 2014 Nov;53(11):1940-50. doi: 10.1093/rheumatology/keu195. Epub 2014 May 15. Review.


Direct and indirect rituximab-induced T cell depletion: comment on the article by Mélet et Al.

Eggleton P, Bremer E.

Arthritis Rheumatol. 2014 Apr;66(4):1053. doi: 10.1002/art.38347. No abstract available.


Meta-analysis as a diagnostic tool for predicting disease onset and/or activity in systemic lupus erythematosus.

Cottrell I, Khan A, Maqsood S, Thornes J, Eggleton P.

Methods Mol Biol. 2014;1134:249-59. doi: 10.1007/978-1-4939-0326-9_19.

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