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Statistical Challenges in the Analysis of Health-Related Quality of Life in Cancer Clinical Trials.

Bonnetain F, Fiteni F, Efficace F, Anota A.

J Clin Oncol. 2016 Apr 18. pii: JCO567974. [Epub ahead of print] No abstract available.


Improving accuracy of prognosis in patients with myelodysplastic syndromes using self-reported quality of life data. Opportunities for a new research agenda in developing prognostic models.

Niscola P, Mandelli F, Efficace F.

Expert Rev Hematol. 2016 May;9(5):415-7. doi: 10.1586/17474086.2016.1164030. Epub 2016 Mar 24. No abstract available.


Prospective international validation of the Quality of Life in Myelodysplasia Scale (QUALMS).

Abel GA, Efficace F, Buckstein RJ, Tinsley S, Jurcic JG, Martins Y, Steensma DP, Watts CD, Raza A, Lee SJ, List AF, Klaassen RJ.

Haematologica. 2016 Mar 4. pii: haematol.2015.140335. [Epub ahead of print]


Developing a core set of patient-reported outcomes in pancreatic cancer: A Delphi survey.

Gerritsen A, Jacobs M, Henselmans I, van Hattum J, Efficace F, Creemers GJ, de Hingh IH, Koopman M, Molenaar IQ, Wilmink HW, Busch OR, Besselink MG, van Laarhoven HW; Dutch Pancreatic Cancer Group.

Eur J Cancer. 2016 Apr;57:68-77. doi: 10.1016/j.ejca.2016.01.001. Epub 2016 Feb 14.


Patient-reported outcomes in head and neck and thyroid cancer randomised controlled trials: A systematic review of completeness of reporting and impact on interpretation.

Mercieca-Bebber RL, Perreca A, King M, Macann A, Whale K, Soldati S, Jacobs M, Efficace F.

Eur J Cancer. 2016 Mar;56:144-61. doi: 10.1016/j.ejca.2015.12.025. Epub 2016 Feb 4. Review.


Systematic Review of the Side Effects Associated With Anti-HER2-Targeted Therapies Used in the Treatment of Breast Cancer, on Behalf of the EORTC Quality of Life Group.

Sodergren SC, Copson E, White A, Efficace F, Sprangers M, Fitzsimmons D, Bottomley A, Johnson CD.

Target Oncol. 2015 Dec 18. [Epub ahead of print]


The impact of comorbidity on health-related quality of life in elderly patients with chronic myeloid leukemia.

Efficace F, Rosti G, Breccia M, Cottone F, Giesinger JM, Stagno F, Iurlo A, Russo Rossi A, Luciano L, Martino B, Galimberti S, Turri D, Bergamaschi M, Tiribelli M, Fava C, Angelucci E, Mandelli F, Baccarani M.

Ann Hematol. 2016 Jan;95(2):211-9. doi: 10.1007/s00277-015-2541-6. Epub 2015 Nov 7.


Time to improve health-related quality of life outcomes in patients with acute promyelocytic leukemia.

Efficace F, Mandelli F, Platzbecker U, Cottone F, Lo Coco F.

Blood. 2015 Nov 26;126(22):2523-4. doi: 10.1182/blood-2015-07-658922. Epub 2015 Oct 9. No abstract available.


Prognostic value of self-reported fatigue on overall survival in patients with myelodysplastic syndromes: a multicentre, prospective, observational, cohort study.

Efficace F, Gaidano G, Breccia M, Voso MT, Cottone F, Angelucci E, Caocci G, Stauder R, Selleslag D, Sprangers M, Platzbecker U, Ricco A, Sanpaolo G, Beyne-Rauzy O, Buccisano F, Palumbo GA, Bowen D, Nguyen K, Niscola P, Vignetti M, Mandelli F.

Lancet Oncol. 2015 Nov;16(15):1506-14. doi: 10.1016/S1470-2045(15)00206-5. Epub 2015 Sep 21.


Health-related quality of life and symptom assessment in randomized controlled trials of patients with leukemia and myelodysplastic syndromes: What have we learned?

Cannella L, Caocci G, Jacobs M, Vignetti M, Mandelli F, Efficace F.

Crit Rev Oncol Hematol. 2015 Dec;96(3):542-54. doi: 10.1016/j.critrevonc.2015.07.012. Epub 2015 Aug 1. Review.


Adherence and future discontinuation of tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia. A patient-based survey on 1133 patients.

Breccia M, Efficace F, Sica S, Abruzzese E, Cedrone M, Turri D, Gobbi M, Carella AM, Gozzini A, Usala E, Cavazzini F, Danise P, Tiribelli M, Binotto G, Pregno P, Bocchia M, Gaidano G, Crugnola M, Bonifacio M, Avanzini P, Celesti F, Guella A, Martino B, Annunziata M, Luciano L, Stagno F, Vallisa D, Pungolino E, Iurlo A, Rambaldi A, Nardiello I, Orlandi E, Gambacorti-Passerini C, Alimena G.

Leuk Res. 2015 Oct;39(10):1055-9. doi: 10.1016/j.leukres.2015.07.004. Epub 2015 Jul 14.


International Society for Quality of Life Research commentary on the draft European Medicines Agency reflection paper on the use of patient-reported outcome (PRO) measures in oncology studies.

Kyte D, Reeve BB, Efficace F, Haywood K, Mercieca-Bebber R, King MT, Norquist JM, Lenderking WR, Snyder C, Ring L, Velikova G, Calvert M.

Qual Life Res. 2016 Feb;25(2):359-62. doi: 10.1007/s11136-015-1099-z. Epub 2015 Aug 15.


Towards a better understanding of the relationship between side effects of analgesia and quality of life in patients with multiple myeloma.

Niscola P, Siniscalchi A, Tendas A, de Fabritiis P, Caravita T, Efficace F.

Support Care Cancer. 2016 Jan;24(1):9-10. doi: 10.1007/s00520-015-2868-5. Epub 2015 Aug 4. No abstract available.


Accuracy of physician assessment of treatment preferences and health status in elderly patients with higher-risk myelodysplastic syndromes.

Caocci G, Voso MT, Angelucci E, Stauder R, Cottone F, Abel G, Nguyen K, Platzbecker U, Beyne-Rauzy O, Gaidano G, Invernizzi R, Molica S, Criscuolo M, Breccia M, Lübbert M, Sanpaolo G, Buccisano F, Ricco A, Palumbo GA, Niscola P, Zhang H, Fenu S, La Nasa G, Mandelli F, Efficace F.

Leuk Res. 2015 Aug;39(8):859-65. doi: 10.1016/j.leukres.2015.05.012. Epub 2015 Jun 12.


Quality of patient-reported outcome reporting across cancer randomized controlled trials according to the CONSORT patient-reported outcome extension: A pooled analysis of 557 trials.

Efficace F, Fayers P, Pusic A, Cemal Y, Yanagawa J, Jacobs M, la Sala A, Cafaro V, Whale K, Rees J, Blazeby J; European Organization for Research and Treatment of Cancer Quality-of-Life Group (Patient-Reported Outcome Measurements Over Time in Oncology Registry).

Cancer. 2015 Sep 15;121(18):3335-42. doi: 10.1002/cncr.29489. Epub 2015 Jun 16.


Systematic Review of Radiation Therapy Toxicity Reporting in Randomized Controlled Trials of Rectal Cancer: A Comparison of Patient-Reported Outcomes and Clinician Toxicity Reporting.

Gilbert A, Ziegler L, Martland M, Davidson S, Efficace F, Sebag-Montefiore D, Velikova G.

Int J Radiat Oncol Biol Phys. 2015 Jul 1;92(3):555-67. doi: 10.1016/j.ijrobp.2015.02.021. Review.


Quality of life and symptom assessment in randomized clinical trials of bladder cancer: A systematic review.

Feuerstein MA, Jacobs M, Piciocchi A, Bochner B, Pusic A, Fayers P, Blazeby J, Efficace F; Patient-Reported Outcome Measurements Over Time In Oncology-PROMOTION Registry.

Urol Oncol. 2015 Jul;33(7):331.e17-23. doi: 10.1016/j.urolonc.2015.04.002. Epub 2015 May 5. Review.


Patient-reported outcomes in randomised controlled trials of colorectal cancer: an analysis determining the availability of robust data to inform clinical decision-making.

Rees JR, Whale K, Fish D, Fayers P, Cafaro V, Pusic A, Blazeby JM, Efficace F.

J Cancer Res Clin Oncol. 2015 Dec;141(12):2181-92. doi: 10.1007/s00432-015-1970-x. Epub 2015 Apr 25. Review.


Reply to M. Koehler et al.

Efficace F, Cottone F, Lo-Coco F.

J Clin Oncol. 2015 Mar 20;33(9):1091-2. doi: 10.1200/JCO.2014.60.3597. Epub 2015 Feb 17. No abstract available.


Prevalence, severity and correlates of fatigue in newly diagnosed patients with myelodysplastic syndromes.

Efficace F, Gaidano G, Breccia M, Criscuolo M, Cottone F, Caocci G, Bowen D, Lübbert M, Angelucci E, Stauder R, Selleslag D, Platzbecker U, Sanpaolo G, Jonasova A, Buccisano F, Specchia G, Palumbo GA, Niscola P, Wan C, Zhang H, Fenu S, Klimek V, Beyne-Rauzy O, Nguyen K, Mandelli F.

Br J Haematol. 2015 Feb;168(3):361-70. doi: 10.1111/bjh.13138. Epub 2014 Oct 1.

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