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Items: 1 to 20 of 88

1.

T cell-intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis.

Martin BN, Wang C, Zhang CJ, Kang Z, Gulen MF, Zepp JA, Zhao J, Bian G, Do JS, Min B, Pavicic PG Jr, El-Sanadi C, Fox PL, Akitsu A, Iwakura Y, Sarkar A, Wewers MD, Kaiser WJ, Mocarski ES, Rothenberg ME, Hise AG, Dubyak GR, Ransohoff RM, Li X.

Nat Immunol. 2016 May;17(5):583-92. doi: 10.1038/ni.3389. Epub 2016 Mar 21.

PMID:
26998763
2.

Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.

Kang S, Fernandes-Alnemri T, Rogers C, Mayes L, Wang Y, Dillon C, Roback L, Kaiser W, Oberst A, Sagara J, Fitzgerald KA, Green DR, Zhang J, Mocarski ES, Alnemri ES.

Nat Commun. 2015 Jun 24;6:7515. doi: 10.1038/ncomms8515.

3.

Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.

Antonopoulos C, Russo HM, El Sanadi C, Martin BN, Li X, Kaiser WJ, Mocarski ES, Dubyak GR.

J Biol Chem. 2015 Aug 14;290(33):20167-84. doi: 10.1074/jbc.M115.652321. Epub 2015 Jun 22.

PMID:
26100631
4.

Manipulation of apoptosis and necroptosis signaling by herpesviruses.

Guo H, Kaiser WJ, Mocarski ES.

Med Microbiol Immunol. 2015 Jun;204(3):439-48. doi: 10.1007/s00430-015-0410-5. Epub 2015 Apr 1. Review.

PMID:
25828583
5.

Necroptosis: The Trojan horse in cell autonomous antiviral host defense.

Mocarski ES, Guo H, Kaiser WJ.

Virology. 2015 May;479-480:160-6. doi: 10.1016/j.virol.2015.03.016. Epub 2015 Mar 24. Review.

6.

Stanley Plotkin: the bright spark of cytomegalovirus vaccines.

Mocarski ES.

Med Microbiol Immunol. 2015 Jun;204(3):243-5. doi: 10.1007/s00430-015-0392-3. Epub 2015 Mar 20. No abstract available.

PMID:
25791891
7.

Suppression of RIP3-dependent necroptosis by human cytomegalovirus.

Omoto S, Guo H, Talekar GR, Roback L, Kaiser WJ, Mocarski ES.

J Biol Chem. 2015 May 1;290(18):11635-48. doi: 10.1074/jbc.M115.646042. Epub 2015 Mar 16.

8.

The A, B, Cs of herpesvirus capsids.

Tandon R, Mocarski ES, Conway JF.

Viruses. 2015 Feb 26;7(3):899-914. doi: 10.3390/v7030899. Review.

9.

Herpes simplex virus suppresses necroptosis in human cells.

Guo H, Omoto S, Harris PA, Finger JN, Bertin J, Gough PJ, Kaiser WJ, Mocarski ES.

Cell Host Microbe. 2015 Feb 11;17(2):243-51. doi: 10.1016/j.chom.2015.01.003.

10.

The immunological underpinnings of vaccinations to prevent cytomegalovirus disease.

McCormick AL, Mocarski ES.

Cell Mol Immunol. 2015 Mar;12(2):170-9. doi: 10.1038/cmi.2014.120. Epub 2014 Dec 29. Review.

11.

RIP3 induces apoptosis independent of pronecrotic kinase activity.

Mandal P, Berger SB, Pillay S, Moriwaki K, Huang C, Guo H, Lich JD, Finger J, Kasparcova V, Votta B, Ouellette M, King BW, Wisnoski D, Lakdawala AS, DeMartino MP, Casillas LN, Haile PA, Sehon CA, Marquis RW, Upton J, Daley-Bauer LP, Roback L, Ramia N, Dovey CM, Carette JE, Chan FK, Bertin J, Gough PJ, Mocarski ES, Kaiser WJ.

Mol Cell. 2014 Nov 20;56(4):481-95. doi: 10.1016/j.molcel.2014.10.021. Epub 2014 Nov 20.

12.

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

Rickard JA, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, Lalaoui N, Lawlor KE, Vanyai H, Hall C, Bankovacki A, Gangoda L, Wong WW, Corbin J, Huang C, Mocarski ES, Murphy JM, Alexander WS, Voss AK, Vaux DL, Kaiser WJ, Walczak H, Silke J.

Elife. 2014 Dec 2;3. doi: 10.7554/eLife.03464.

13.

Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans.

Ganesan S, Rathinam VA, Bossaller L, Army K, Kaiser WJ, Mocarski ES, Dillon CP, Green DR, Mayadas TN, Levitz SM, Hise AG, Silverman N, Fitzgerald KA.

J Immunol. 2014 Sep 1;193(5):2519-30. doi: 10.4049/jimmunol.1400276. Epub 2014 Jul 25.

14.

Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.

Berger SB, Kasparcova V, Hoffman S, Swift B, Dare L, Schaeffer M, Capriotti C, Cook M, Finger J, Hughes-Earle A, Harris PA, Kaiser WJ, Mocarski ES, Bertin J, Gough PJ.

J Immunol. 2014 Jun 15;192(12):5476-80. doi: 10.4049/jimmunol.1400499. Epub 2014 May 12.

15.

RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition.

Kaiser WJ, Daley-Bauer LP, Thapa RJ, Mandal P, Berger SB, Huang C, Sundararajan A, Guo H, Roback L, Speck SH, Bertin J, Gough PJ, Balachandran S, Mocarski ES.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7753-8. doi: 10.1073/pnas.1401857111. Epub 2014 May 12.

16.

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

Weng D, Marty-Roix R, Ganesan S, Proulx MK, Vladimer GI, Kaiser WJ, Mocarski ES, Pouliot K, Chan FK, Kelliher MA, Harris PA, Bertin J, Gough PJ, Shayakhmetov DM, Goguen JD, Fitzgerald KA, Silverman N, Lien E.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7391-6. doi: 10.1073/pnas.1403477111. Epub 2014 May 5.

17.

Cytomegalovirus hijacks CX3CR1(hi) patrolling monocytes as immune-privileged vehicles for dissemination in mice.

Daley-Bauer LP, Roback LJ, Wynn GM, Mocarski ES.

Cell Host Microbe. 2014 Mar 12;15(3):351-62. doi: 10.1016/j.chom.2014.02.002.

18.

True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity.

Mocarski ES, Kaiser WJ, Livingston-Rosanoff D, Upton JW, Daley-Bauer LP.

J Immunol. 2014 Mar 1;192(5):2019-26. doi: 10.4049/jimmunol.1302426. Review.

19.

Highly acidic C-terminal region of cytomegalovirus pUL96 determines its functions during virus maturation independently of a direct pp150 interaction.

Brechtel TM, Mocarski ES, Tandon R.

J Virol. 2014 Apr;88(8):4493-503. doi: 10.1128/JVI.03784-13. Epub 2014 Feb 5.

20.

Transcription of true late (γ2) cytomegalovirus genes requires UL92 function that is conserved among beta- and gammaherpesviruses.

Omoto S, Mocarski ES.

J Virol. 2014 Jan;88(1):120-30. doi: 10.1128/JVI.02983-13. Epub 2013 Oct 16.

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