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Results: 1 to 20 of 78

1.

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity.

Mandal P, Berger SB, Pillay S, Moriwaki K, Huang C, Guo H, Lich JD, Finger J, Kasparcova V, Votta B, Ouellette M, King BW, Wisnoski D, Lakdawala AS, DeMartino MP, Casillas LN, Haile PA, Sehon CA, Marquis RW, Upton J, Daley-Bauer LP, Roback L, Ramia N, Dovey CM, Carette JE, Chan FK, Bertin J, Gough PJ, Mocarski ES, Kaiser WJ.

Mol Cell. 2014 Nov 20;56(4):481-95. doi: 10.1016/j.molcel.2014.10.021. Epub 2014 Nov 20.

PMID:
25459880
[PubMed - in process]
2.

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

Rickard JA, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, Lalaoui N, Lawlor KE, Vanyai H, Hall C, Bankovacki A, Gangoda L, Wong WW, Corbin J, Huang C, Mocarski ES, Murphy JM, Alexander WS, Voss AK, Vaux DL, Kaiser WJ, Walczak H, Silke J.

Elife. 2014 Dec 2;3. doi: 10.7554/eLife.03464.

PMID:
25443632
[PubMed - in process]
Free Article
3.

Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans.

Ganesan S, Rathinam VA, Bossaller L, Army K, Kaiser WJ, Mocarski ES, Dillon CP, Green DR, Mayadas TN, Levitz SM, Hise AG, Silverman N, Fitzgerald KA.

J Immunol. 2014 Sep 1;193(5):2519-30. doi: 10.4049/jimmunol.1400276. Epub 2014 Jul 25.

PMID:
25063877
[PubMed - indexed for MEDLINE]
4.

Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.

Berger SB, Kasparcova V, Hoffman S, Swift B, Dare L, Schaeffer M, Capriotti C, Cook M, Finger J, Hughes-Earle A, Harris PA, Kaiser WJ, Mocarski ES, Bertin J, Gough PJ.

J Immunol. 2014 Jun 15;192(12):5476-80. doi: 10.4049/jimmunol.1400499. Epub 2014 May 12.

PMID:
24821972
[PubMed - indexed for MEDLINE]
5.

RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition.

Kaiser WJ, Daley-Bauer LP, Thapa RJ, Mandal P, Berger SB, Huang C, Sundararajan A, Guo H, Roback L, Speck SH, Bertin J, Gough PJ, Balachandran S, Mocarski ES.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7753-8. doi: 10.1073/pnas.1401857111. Epub 2014 May 12.

PMID:
24821786
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

Weng D, Marty-Roix R, Ganesan S, Proulx MK, Vladimer GI, Kaiser WJ, Mocarski ES, Pouliot K, Chan FK, Kelliher MA, Harris PA, Bertin J, Gough PJ, Shayakhmetov DM, Goguen JD, Fitzgerald KA, Silverman N, Lien E.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7391-6. doi: 10.1073/pnas.1403477111. Epub 2014 May 5.

PMID:
24799678
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Cytomegalovirus hijacks CX3CR1(hi) patrolling monocytes as immune-privileged vehicles for dissemination in mice.

Daley-Bauer LP, Roback LJ, Wynn GM, Mocarski ES.

Cell Host Microbe. 2014 Mar 12;15(3):351-62. doi: 10.1016/j.chom.2014.02.002.

PMID:
24629341
[PubMed - indexed for MEDLINE]
8.

True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity.

Mocarski ES, Kaiser WJ, Livingston-Rosanoff D, Upton JW, Daley-Bauer LP.

J Immunol. 2014 Mar 1;192(5):2019-26. doi: 10.4049/jimmunol.1302426. Review.

PMID:
24563506
[PubMed - indexed for MEDLINE]
9.

Highly acidic C-terminal region of cytomegalovirus pUL96 determines its functions during virus maturation independently of a direct pp150 interaction.

Brechtel TM, Mocarski ES, Tandon R.

J Virol. 2014 Apr;88(8):4493-503. doi: 10.1128/JVI.03784-13. Epub 2014 Feb 5.

PMID:
24501413
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Transcription of true late (γ2) cytomegalovirus genes requires UL92 function that is conserved among beta- and gammaherpesviruses.

Omoto S, Mocarski ES.

J Virol. 2014 Jan;88(1):120-30. doi: 10.1128/JVI.02983-13. Epub 2013 Oct 16.

PMID:
24131715
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Priorities for CMV vaccine development.

Krause PR, Bialek SR, Boppana SB, Griffiths PD, Laughlin CA, Ljungman P, Mocarski ES, Pass RF, Read JS, Schleiss MR, Plotkin SA.

Vaccine. 2013 Dec 17;32(1):4-10. doi: 10.1016/j.vaccine.2013.09.042. Epub 2013 Oct 13. Review.

PMID:
24129123
[PubMed - indexed for MEDLINE]
12.

Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells.

Antonopoulos C, El Sanadi C, Kaiser WJ, Mocarski ES, Dubyak GR.

J Immunol. 2013 Nov 1;191(9):4789-803. doi: 10.4049/jimmunol.1300645. Epub 2013 Sep 27.

PMID:
24078693
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

Kaiser WJ, Sridharan H, Huang C, Mandal P, Upton JW, Gough PJ, Sehon CA, Marquis RW, Bertin J, Mocarski ES.

J Biol Chem. 2013 Oct 25;288(43):31268-79. doi: 10.1074/jbc.M113.462341. Epub 2013 Sep 9.

PMID:
24019532
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Natural antisense transcripts of UL123 packaged in human cytomegalovirus virions.

Yang CQ, Miao LF, Pan X, Wu CC, Rayner S, Mocarski ES, Ye HQ, Luo MH.

Arch Virol. 2014 Jan;159(1):147-51. doi: 10.1007/s00705-013-1793-5. Epub 2013 Jul 25.

PMID:
23884634
[PubMed - indexed for MEDLINE]
15.

Viral modulation of programmed necrosis.

Kaiser WJ, Upton JW, Mocarski ES.

Curr Opin Virol. 2013 Jun;3(3):296-306. doi: 10.1016/j.coviro.2013.05.019. Epub 2013 Jun 15. Review.

PMID:
23773332
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Cytomegalovirus UL91 is essential for transcription of viral true late (γ2) genes.

Omoto S, Mocarski ES.

J Virol. 2013 Aug;87(15):8651-64. doi: 10.1128/JVI.01052-13. Epub 2013 May 29.

PMID:
23720731
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The need and challenges for development of an Epstein-Barr virus vaccine.

Cohen JI, Mocarski ES, Raab-Traub N, Corey L, Nabel GJ.

Vaccine. 2013 Apr 18;31 Suppl 2:B194-6. doi: 10.1016/j.vaccine.2012.09.041. Review.

PMID:
23598481
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Gene products of the embedded m41/m41.1 locus of murine cytomegalovirus differentially influence replication and pathogenesis.

Crosby LN, McCormick AL, Mocarski ES.

Virology. 2013 Feb 20;436(2):274-83. doi: 10.1016/j.virol.2012.12.002. Epub 2013 Jan 5.

PMID:
23295021
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Multiplicity-dependent activation of a serine protease-dependent cytomegalovirus-associated programmed cell death pathway.

McCormick AL, Roback L, Wynn G, Mocarski ES.

Virology. 2013 Jan 20;435(2):250-7. doi: 10.1016/j.virol.2012.08.042. Epub 2012 Nov 14.

PMID:
23159167
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner.

Bossaller L, Chiang PI, Schmidt-Lauber C, Ganesan S, Kaiser WJ, Rathinam VA, Mocarski ES, Subramanian D, Green DR, Silverman N, Fitzgerald KA, Marshak-Rothstein A, Latz E.

J Immunol. 2012 Dec 15;189(12):5508-12. doi: 10.4049/jimmunol.1202121. Epub 2012 Nov 9.

PMID:
23144495
[PubMed - indexed for MEDLINE]
Free PMC Article

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