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The childhood solid tumor network: A new resource for the developmental biology and oncology research Communities.

Stewart E, Federico S, Karlstrom A, Shelat A, Sablauer A, Pappo A, Dyer MA.

Dev Biol. 2015 Apr 9. pii: S0012-1606(15)00060-3. doi: 10.1016/j.ydbio.2015.02.002. [Epub ahead of print] Review.


Genomic landscape of paediatric adrenocortical tumours.

Pinto EM, Chen X, Easton J, Finkelstein D, Liu Z, Pounds S, Rodriguez-Galindo C, Lund TC, Mardis ER, Wilson RK, Boggs K, Yergeau D, Cheng J, Mulder HL, Manne J, Jenkins J, Mastellaro MJ, Figueiredo BC, Dyer MA, Pappo A, Zhang J, Downing JR, Ribeiro RC, Zambetti GP.

Nat Commun. 2015 Mar 6;6:6302. doi: 10.1038/ncomms7302.


Pediatric solid tumor genomics and developmental pliancy.

Chen X, Pappo A, Dyer MA.

Oncogene. 2015 Feb 2. doi: 10.1038/onc.2014.474. [Epub ahead of print] Review.


Genetically engineered mouse and orthotopic human tumor xenograft models of retinoblastoma.

Benavente CA, Dyer MA.

Methods Mol Biol. 2015;1267:307-17. doi: 10.1007/978-1-4939-2297-0_15.


Genetics and epigenetics of human retinoblastoma.

Benavente CA, Dyer MA.

Annu Rev Pathol. 2015;10:547-62. doi: 10.1146/annurev-pathol-012414-040259.


Targeting the DNA repair pathway in Ewing sarcoma.

Stewart E, Goshorn R, Bradley C, Griffiths LM, Benavente C, Twarog NR, Miller GM, Caufield W, Freeman BB 3rd, Bahrami A, Pappo A, Wu J, Loh A, Karlström Å, Calabrese C, Gordon B, Tsurkan L, Hatfield MJ, Potter PM, Snyder SE, Thiagarajan S, Shirinifard A, Sablauer A, Shelat AA, Dyer MA.

Cell Rep. 2014 Nov 6;9(3):829-41. doi: 10.1016/j.celrep.2014.09.028. Epub 2014 Oct 23.


Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression.

Benavente CA, Finkelstein D, Johnson DA, Marine JC, Ashery-Padan R, Dyer MA.

Oncotarget. 2014 Oct 30;5(20):9594-608.


Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells.

Miles WO, Korenjak M, Griffiths LM, Dyer MA, Provero P, Dyson NJ.

EMBO J. 2014 Oct 1;33(19):2201-15. doi: 10.15252/embj.201488057. Epub 2014 Aug 6.


The role of whole brain radiation therapy in the management of melanoma brain metastases.

Dyer MA, Arvold ND, Chen YH, Pinnell NE, Mitin T, Lee EQ, Hodi FS, Ibrahim N, Weiss SE, Kelly PJ, Floyd SR, Mahadevan A, Alexander BM.

Radiat Oncol. 2014 Jun 22;9:143. doi: 10.1186/1748-717X-9-143.


Pharmacokinetics and efficacy of the spleen tyrosine kinase inhibitor r406 after ocular delivery for retinoblastoma.

Pritchard EM, Stewart E, Zhu F, Bradley C, Griffiths L, Yang L, Suryadevara PK, Zhang J, Freeman BB 3rd, Guy RK, Dyer MA.

Pharm Res. 2014 Nov;31(11):3060-72. doi: 10.1007/s11095-014-1399-y. Epub 2014 Jun 7.


The ATRX cDNA is prone to bacterial IS10 element insertions that alter its structure.

Valle-García D, Griffiths LM, Dyer MA, Bernstein E, Recillas-Targa F.

Springerplus. 2014 May 2;3:222. doi: 10.1186/2193-1801-3-222. eCollection 2014.


Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma.

Chen X, Bahrami A, Pappo A, Easton J, Dalton J, Hedlund E, Ellison D, Shurtleff S, Wu G, Wei L, Parker M, Rusch M, Nagahawatte P, Wu J, Mao S, Boggs K, Mulder H, Yergeau D, Lu C, Ding L, Edmonson M, Qu C, Wang J, Li Y, Navid F, Daw NC, Mardis ER, Wilson RK, Downing JR, Zhang J, Dyer MA; St. Jude Children’s Research Hospital–Washington University Pediatric Cancer Genome Project.

Cell Rep. 2014 Apr 10;7(1):104-12. doi: 10.1016/j.celrep.2014.03.003. Epub 2014 Apr 3.


RB1 gene inactivation by chromothripsis in human retinoblastoma.

McEvoy J, Nagahawatte P, Finkelstein D, Richards-Yutz J, Valentine M, Ma J, Mullighan C, Song G, Chen X, Wilson M, Brennan R, Pounds S, Becksfort J, Huether R, Lu C, Fulton RS, Fulton LL, Hong X, Dooling DJ, Ochoa K, Mardis ER, Wilson RK, Easton J, Zhang J, Downing JR, Ganguly A, Dyer MA.

Oncotarget. 2014 Jan 30;5(2):438-50.


Targeting oxidative stress in embryonal rhabdomyosarcoma.

Chen X, Stewart E, Shelat AA, Qu C, Bahrami A, Hatley M, Wu G, Bradley C, McEvoy J, Pappo A, Spunt S, Valentine MB, Valentine V, Krafcik F, Lang WH, Wierdl M, Tsurkan L, Tolleman V, Federico SM, Morton C, Lu C, Ding L, Easton J, Rusch M, Nagahawatte P, Wang J, Parker M, Wei L, Hedlund E, Finkelstein D, Edmonson M, Shurtleff S, Boggs K, Mulder H, Yergeau D, Skapek S, Hawkins DS, Ramirez N, Potter PM, Sandoval JA, Davidoff AM, Mardis ER, Wilson RK, Zhang J, Downing JR, Dyer MA; St. Jude Children’s Research Hospital–Washington University Pediatric Cancer Genome Project.

Cancer Cell. 2013 Dec 9;24(6):710-24. doi: 10.1016/j.ccr.2013.11.002.


Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm.

Zhang H, Nieves JL, Fraser ST, Isern J, Douvaras P, Papatsenko D, D'Souza SL, Lemischka IR, Dyer MA, Baron MH.

Stem Cells. 2014 Jan;32(1):191-203. doi: 10.1002/stem.1536.


Cross-species genomic and epigenomic landscape of retinoblastoma.

Benavente CA, McEvoy JD, Finkelstein D, Wei L, Kang G, Wang YD, Neale G, Ragsdale S, Valentine V, Bahrami A, Temirov J, Pounds S, Zhang J, Dyer MA.

Oncotarget. 2013 Jun;4(6):844-59.


An Open Trial of Relapse Prevention Therapy for Smokers With Schizophrenia.

Cather C, Dyer MA, Burrell HA, Hoeppner B, Goff DC, Evins AE.

J Dual Diagn. 2013;9(1):87-93.


Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

Cheung NK, Dyer MA.

Nat Rev Cancer. 2013 Jun;13(6):397-411. doi: 10.1038/nrc3526. Review.


Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma.

McEvoy J, Ulyanov A, Brennan R, Wu G, Pounds S, Zhang J, Dyer MA.

PLoS One. 2012;7(8):e42739. doi: 10.1371/journal.pone.0042739. Epub 2012 Aug 20.


Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation.

Nittner D, Lambertz I, Clermont F, Mestdagh P, Köhler C, Nielsen SJ, Jochemsen A, Speleman F, Vandesompele J, Dyer MA, Schramm A, Schulte JH, Marine JC.

Nat Cell Biol. 2012 Sep;14(9):958-65. doi: 10.1038/ncb2556. Epub 2012 Aug 5.

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