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Specific antibody responses as indicators of treatment efficacy for visceral leishmaniasis.

Vallur AC, Hailu A, Mondal D, Reinhart C, Wondimu H, Tutterrow Y, Ghalib HW, Reed SG, Duthie MS.

Eur J Clin Microbiol Infect Dis. 2015 Apr;34(4):679-86. doi: 10.1007/s10096-014-2282-9. Epub 2014 Nov 19.


Squalene emulsion potentiates the adjuvant activity of the TLR4 agonist, GLA, via inflammatory caspases, IL-18, and IFN-γ.

Desbien AL, Reed SJ, Bailor HR, Dubois Cauwelaert N, Laurance JD, Orr MT, Fox CB, Carter D, Reed SG, Duthie MS.

Eur J Immunol. 2015 Feb;45(2):407-17. doi: 10.1002/eji.201444543. Epub 2014 Dec 3.


Interleukin 17A acts synergistically with interferon γ to promote protection against Leishmania infantum infection.

Nascimento MS, Carregaro V, Lima-Júnior DS, Costa DL, Ryffel B, Duthie MS, de Jesus A, de Almeida RP, da Silva JS.

J Infect Dis. 2015 Mar 15;211(6):1015-26. doi: 10.1093/infdis/jiu531. Epub 2014 Oct 1.


Evaluation of novel tools to facilitate the detection and characterization of leprosy patients in China.

Wen Y, You YG, Yuan LC, Yuan YH, Zhang Y, Duthie MS, Li HY.

Biomed Res Int. 2014;2014:371828. doi: 10.1155/2014/371828. Epub 2014 Aug 12.


Protection against Mycobacterium leprae infection by the ID83/GLA-SE and ID93/GLA-SE vaccines developed for tuberculosis.

Duthie MS, Coler RN, Laurance JD, Sampaio LH, Oliveira RM, Sousa AL, Stefani MM, Maeda Y, Matsuoka M, Makino M, Reed SG.

Infect Immun. 2014 Sep;82(9):3979-85. doi: 10.1128/IAI.02145-14. Epub 2014 Jul 14.


Utility of recombinant proteins LID-1 and PADL in screening for Mycobacterium leprae infection and leprosy.

de Souza MM, Netto EM, Nakatani M, Duthie MS.

Trans R Soc Trop Med Hyg. 2014 Aug;108(8):495-501. doi: 10.1093/trstmh/tru093. Epub 2014 Jun 7.


A nanoliposome delivery system to synergistically trigger TLR4 AND TLR7.

Fox CB, Sivananthan SJ, Duthie MS, Vergara J, Guderian JA, Moon E, Coblentz D, Reed SG, Carter D.

J Nanobiotechnology. 2014 Apr 26;12:17. doi: 10.1186/1477-3155-12-17.


A rapid ELISA for the diagnosis of MB leprosy based on complementary detection of antibodies against a novel protein-glycolipid conjugate.

Duthie MS, Raychaudhuri R, Tutterrow YL, Misquith A, Bowman J, Casey A, Balagon MF, Maghanoy A, Beltran-Alzate JC, Romero-Alzate M, Cardona-Castro N, Reed SG.

Diagn Microbiol Infect Dis. 2014 Jun;79(2):233-9. doi: 10.1016/j.diagmicrobio.2014.02.006. Epub 2014 Feb 24.


Synergistic antigen combinations for the development of interferon gamma release assays for paucibacillary leprosy.

Oliveira RM, Hungria EM, de Araújo Freitas A, de Sousa AL, Costa MB, Reed SG, Duthie MS, Stefani MM.

Eur J Clin Microbiol Infect Dis. 2014 Aug;33(8):1415-24. doi: 10.1007/s10096-014-2077-z. Epub 2014 Mar 12.


Micronutrients influencing the immune response in leprosy.

Passos Vázquez CM, Mendes Netto RS, Ferreira Barbosa KB, Rodrigues de Moura T, de Almeida RP, Duthie MS, Ribeiro de Jesus A.

Nutr Hosp. 2014 Jan 1;29(1):26-36. doi: 10.3305/nh.2014.29.1.6988.


Rapid quantitative serological test for detection of infection with Mycobacterium leprae, the causative agent of leprosy.

Duthie MS, Balagon MF, Maghanoy A, Orcullo FM, Cang M, Dias RF, Collovati M, Reed SG.

J Clin Microbiol. 2014 Feb;52(2):613-9. doi: 10.1128/JCM.02085-13. Epub 2013 Dec 11.


Optimizing manufacturing and composition of a TLR4 nanosuspension: physicochemical stability and vaccine adjuvant activity.

Fung HW, Mikasa TJ, Vergara J, Sivananthan SJ, Guderian JA, Duthie MS, Vedvick TS, Fox CB.

J Nanobiotechnology. 2013 Dec 21;11:43. doi: 10.1186/1477-3155-11-43.


Biomarkers for intracellular pathogens: establishing tools as vaccine and therapeutic endpoints for visceral leishmaniasis.

Vallur AC, Duthie MS, Reinhart C, Tutterrow Y, Hamano S, Bhaskar KR, Coler RN, Mondal D, Reed SG.

Clin Microbiol Infect. 2014 Jun;20(6):O374-83. doi: 10.1111/1469-0691.12421. Epub 2013 Nov 18.


Alteration of the serum biomarker profiles of visceral leishmaniasis during treatment.

Duthie MS, Guderian J, Vallur A, Bhatia A, Lima dos Santos P, Vieira de Melo E, Ribeiro de Jesus A, Todt M, Mondal D, Almeida R, Reed SG.

Eur J Clin Microbiol Infect Dis. 2014 Apr;33(4):639-49. doi: 10.1007/s10096-013-1999-1. Epub 2013 Oct 31.


Development of a quantitative rapid diagnostic test for multibacillary leprosy using smart phone technology.

Paula Vaz Cardoso L, Dias RF, Freitas AA, Hungria EM, Oliveira RM, Collovati M, Reed SG, Duthie MS, Martins Araújo Stefani M.

BMC Infect Dis. 2013 Oct 23;13:497. doi: 10.1186/1471-2334-13-497.


High levels of soluble CD40 ligand and matrix metalloproteinase-9 in serum are associated with favorable clinical evolution in human visceral leishmaniasis.

de Oliveira FA, Vanessa Oliveira Silva C, Damascena NP, Passos RO, Duthie MS, Guderian JA, Bhatia A, de Moura TR, Reed SG, de Almeida RP, de Jesus AR.

BMC Infect Dis. 2013 Jul 19;13(1):331. doi: 10.1186/1471-2334-13-331.


Development of a high density hemagglutinin protein microarray to determine the breadth of influenza antibody responses.

Desbien AL, Van Hoeven N, Reed SJ, Casey AC, Laurance JD, Baldwin SL, Duthie MS, Reed SG, Carter D.

Biotechniques. 2013 Jun;54(6):345-8. doi: 10.2144/000114041.


MyD88 and TRIF synergistic interaction is required for TH1-cell polarization with a synthetic TLR4 agonist adjuvant.

Orr MT, Duthie MS, Windish HP, Lucas EA, Guderian JA, Hudson TE, Shaverdian N, O'Donnell J, Desbien AL, Reed SG, Coler RN.

Eur J Immunol. 2013 Sep;43(9):2398-408. doi: 10.1002/eji.201243124. Epub 2013 Jul 3.


Early Revelation of Leprosy in China by Sequential Antibody Analyses with LID-1 and PGL-I.

Qiong-Hua P, Zhong-Yi Z, Jun Y, Yan W, Lian-Chao Y, Huan-Ying L, Reed SG, Duthie MS.

J Trop Med. 2013;2013:352689. doi: 10.1155/2013/352689. Epub 2013 Jan 28.


The potential for vaccination in leprosy elimination: new tools for targeted interventions.

Duthie MS, Saunderson P, Reed SG.

Mem Inst Oswaldo Cruz. 2012 Dec;107 Suppl 1:190-6.

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