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Results: 1 to 20 of 77

1.

Antiphospholipid Antibodies Alter Cell-Death-Regulating Lipid Metabolites in First and Third Trimester Human Placentae.

Pantham P, Heazell AE, Mullard G, Begley P, Chen Q, Brown M, Dunn WB, Chamley LW.

Am J Reprod Immunol. 2015 Apr 9. doi: 10.1111/aji.12387. [Epub ahead of print]

PMID:
25856778
2.

Profiling of spatial metabolite distributions in wheat leaves under normal and nitrate limiting conditions.

Allwood JW, Chandra S, Xu Y, Dunn WB, Correa E, Hopkins L, Goodacre R, Tobin AK, Bowsher CG.

Phytochemistry. 2015 Feb 10. pii: S0031-9422(15)00042-4. doi: 10.1016/j.phytochem.2015.01.007. [Epub ahead of print]

3.

Molecular phenotyping of a UK population: defining the human serum metabolome.

Dunn WB, Lin W, Broadhurst D, Begley P, Brown M, Zelena E, Vaughan AA, Halsall A, Harding N, Knowles JD, Francis-McIntyre S, Tseng A, Ellis DI, O'Hagan S, Aarons G, Benjamin B, Chew-Graham S, Moseley C, Potter P, Winder CL, Potts C, Thornton P, McWhirter C, Zubair M, Pan M, Burns A, Cruickshank JK, Jayson GC, Purandare N, Wu FC, Finn JD, Haselden JN, Nicholls AW, Wilson ID, Goodacre R, Kell DB.

Metabolomics. 2015;11:9-26. Epub 2014 Jul 25.

4.

Untargeted metabolic profiling identifies altered serum metabolites of type 2 diabetes mellitus in a prospective, nested case control study.

Drogan D, Dunn WB, Lin W, Buijsse B, Schulze MB, Langenberg C, Brown M, Floegel A, Dietrich S, Rolandsson O, Wedge DC, Goodacre R, Forouhi NG, Sharp SJ, Spranger J, Wareham NJ, Boeing H.

Clin Chem. 2015 Mar;61(3):487-97. doi: 10.1373/clinchem.2014.228965. Epub 2014 Dec 18.

PMID:
25524438
5.

Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy.

Gehmlich K, Dodd MS, Allwood JW, Kelly M, Bellahcene M, Lad HV, Stockenhuber A, Hooper C, Ashrafian H, Redwood CS, Carrier L, Dunn WB.

Mol Biosyst. 2015 Feb;11(2):564-73. doi: 10.1039/c4mb00594e.

PMID:
25437646
6.

MUSCLE: automated multi-objective evolutionary optimization of targeted LC-MS/MS analysis.

Bradbury J, Genta-Jouve G, Allwood JW, Dunn WB, Goodacre R, Knowles JD, He S, Viant MR.

Bioinformatics. 2015 Mar 15;31(6):975-7. doi: 10.1093/bioinformatics/btu740. Epub 2014 Nov 11.

7.

Evidence that multiple defects in lipid regulation occur before hyperglycemia during the prodrome of type-2 diabetes.

Anderson SG, Dunn WB, Banerjee M, Brown M, Broadhurst DI, Goodacre R, Cooper GJ, Kell DB, Cruickshank JK.

PLoS One. 2014 Sep 3;9(9):e103217. doi: 10.1371/journal.pone.0103217. eCollection 2014.

8.

A metabolomics investigation into the effects of HIV protease inhibitors on HPV16 E6 expressing cervical carcinoma cells.

Kim DH, Allwood JW, Moore RE, Marsden-Edwards E, Dunn WB, Xu Y, Hampson L, Hampson IN, Goodacre R.

Mol Biosyst. 2014 Mar 4;10(3):398-411. doi: 10.1039/c3mb70423h. Epub 2014 Jan 10.

PMID:
24413339
9.

HAMMER: automated operation of mass frontier to construct in silico mass spectral fragmentation libraries.

Zhou J, Weber RJ, Allwood JW, Mistrik R, Zhu Z, Ji Z, Chen S, Dunn WB, He S, Viant MR.

Bioinformatics. 2014 Feb 15;30(4):581-3. doi: 10.1093/bioinformatics/btt711. Epub 2013 Dec 11.

10.

Yeast cells with impaired drug resistance accumulate glycerol and glucose.

Dikicioglu D, Oc S, Rash BM, Dunn WB, Pir P, Kell DB, Kirdar B, Oliver SG.

Mol Biosyst. 2014 Jan;10(1):93-102. doi: 10.1039/c2mb25512j.

PMID:
24157722
11.

A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions.

Kotze HL, Armitage EG, Sharkey KJ, Allwood JW, Dunn WB, Williams KJ, Goodacre R.

BMC Syst Biol. 2013 Oct 23;7:107. doi: 10.1186/1752-0509-7-107.

12.

The role of reporting standards for metabolite annotation and identification in metabolomic studies.

Salek RM, Steinbeck C, Viant MR, Goodacre R, Dunn WB.

Gigascience. 2013 Oct 16;2(1):13. doi: 10.1186/2047-217X-2-13.

13.

A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes.

Smallbone K, Messiha HL, Carroll KM, Winder CL, Malys N, Dunn WB, Murabito E, Swainston N, Dada JO, Khan F, Pir P, Simeonidis E, Spasić I, Wishart J, Weichart D, Hayes NW, Jameson D, Broomhead DS, Oliver SG, Gaskell SJ, McCarthy JE, Paton NW, Westerhoff HV, Kell DB, Mendes P.

FEBS Lett. 2013 Sep 2;587(17):2832-41. doi: 10.1016/j.febslet.2013.06.043. Epub 2013 Jul 4.

14.

Autocrine amplification of integrin αIIbβ3 activation and platelet adhesive responses by deoxyribose-1-phosphate.

Vara DS, Campanella M, Canobbio I, Dunn WB, Pizzorno G, Hirano M, Pula G.

Thromb Haemost. 2013 Jun;109(6):1108-19. doi: 10.1160/TH12-10-0751. Epub 2013 Mar 14.

PMID:
23494007
15.

A community-driven global reconstruction of human metabolism.

Thiele I, Swainston N, Fleming RM, Hoppe A, Sahoo S, Aurich MK, Haraldsdottir H, Mo ML, Rolfsson O, Stobbe MD, Thorleifsson SG, Agren R, Bölling C, Bordel S, Chavali AK, Dobson P, Dunn WB, Endler L, Hala D, Hucka M, Hull D, Jameson D, Jamshidi N, Jonsson JJ, Juty N, Keating S, Nookaew I, Le Novère N, Malys N, Mazein A, Papin JA, Price ND, Selkov E Sr, Sigurdsson MI, Simeonidis E, Sonnenschein N, Smallbone K, Sorokin A, van Beek JH, Weichart D, Goryanin I, Nielsen J, Westerhoff HV, Kell DB, Mendes P, Palsson BØ.

Nat Biotechnol. 2013 May;31(5):419-25. doi: 10.1038/nbt.2488. Epub 2013 Mar 3.

16.

CASMI-The Small Molecule Identification Process from a Birmingham Perspective.

Allwood JW, Weber RJ, Zhou J, He S, Viant MR, Dunn WB.

Metabolites. 2013 May 21;3(2):397-411. doi: 10.3390/metabo3020397.

17.

Liquid chromatography-mass spectrometry calibration transfer and metabolomics data fusion.

Vaughan AA, Dunn WB, Allwood JW, Wedge DC, Blackhall FH, Whetton AD, Dive C, Goodacre R.

Anal Chem. 2012 Nov 20;84(22):9848-57. doi: 10.1021/ac302227c. Epub 2012 Oct 29.

PMID:
23072438
18.

The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans.

Dunn WB, Wilson ID, Nicholls AW, Broadhurst D.

Bioanalysis. 2012 Sep;4(18):2249-64. doi: 10.4155/bio.12.204. Review.

PMID:
23046267
19.

Dupuytren's disease metabolite analyses reveals alterations following initial short-term fibroblast culturing.

Rehman S, Xu Y, Dunn WB, Day PJ, Westerhoff HV, Goodacre R, Bayat A.

Mol Biosyst. 2012 Sep;8(9):2274-88. Epub 2012 Jul 6.

PMID:
22772395
20.

Fingerprinting food: current technologies for the detection of food adulteration and contamination.

Ellis DI, Brewster VL, Dunn WB, Allwood JW, Golovanov AP, Goodacre R.

Chem Soc Rev. 2012 Sep 7;41(17):5706-27. doi: 10.1039/c2cs35138b. Epub 2012 Jun 25. Review.

PMID:
22729179
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