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Results: 1 to 20 of 71

1.

Evidence That Multiple Defects in Lipid Regulation Occur before Hyperglycemia during the Prodrome of Type-2 Diabetes.

Anderson SG, Dunn WB, Banerjee M, Brown M, Broadhurst DI, Goodacre R, Cooper GJ, Kell DB, Cruickshank JK.

PLoS One. 2014 Sep 3;9(9):e103217. doi: 10.1371/journal.pone.0103217. eCollection 2014.

PMID:
25184286
[PubMed - in process]
Free PMC Article
2.

A metabolomics investigation into the effects of HIV protease inhibitors on HPV16 E6 expressing cervical carcinoma cells.

Kim DH, Allwood JW, Moore RE, Marsden-Edwards E, Dunn WB, Xu Y, Hampson L, Hampson IN, Goodacre R.

Mol Biosyst. 2014 Mar 4;10(3):398-411. doi: 10.1039/c3mb70423h. Epub 2014 Jan 10.

PMID:
24413339
[PubMed - in process]
3.

HAMMER: automated operation of mass frontier to construct in silico mass spectral fragmentation libraries.

Zhou J, Weber RJ, Allwood JW, Mistrik R, Zhu Z, Ji Z, Chen S, Dunn WB, He S, Viant MR.

Bioinformatics. 2014 Feb 15;30(4):581-3. doi: 10.1093/bioinformatics/btt711. Epub 2013 Dec 11.

PMID:
24336413
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Yeast cells with impaired drug resistance accumulate glycerol and glucose.

Dikicioglu D, Oc S, Rash BM, Dunn WB, Pir P, Kell DB, Kirdar B, Oliver SG.

Mol Biosyst. 2014 Jan;10(1):93-102. doi: 10.1039/c2mb25512j.

PMID:
24157722
[PubMed - indexed for MEDLINE]
5.

A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions.

Kotze HL, Armitage EG, Sharkey KJ, Allwood JW, Dunn WB, Williams KJ, Goodacre R.

BMC Syst Biol. 2013 Oct 23;7:107. doi: 10.1186/1752-0509-7-107.

PMID:
24153255
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The role of reporting standards for metabolite annotation and identification in metabolomic studies.

Salek RM, Steinbeck C, Viant MR, Goodacre R, Dunn WB.

Gigascience. 2013 Oct 16;2(1):13. doi: 10.1186/2047-217X-2-13.

PMID:
24131531
[PubMed]
Free PMC Article
7.

A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes.

Smallbone K, Messiha HL, Carroll KM, Winder CL, Malys N, Dunn WB, Murabito E, Swainston N, Dada JO, Khan F, Pir P, Simeonidis E, Spasić I, Wishart J, Weichart D, Hayes NW, Jameson D, Broomhead DS, Oliver SG, Gaskell SJ, McCarthy JE, Paton NW, Westerhoff HV, Kell DB, Mendes P.

FEBS Lett. 2013 Sep 2;587(17):2832-41. doi: 10.1016/j.febslet.2013.06.043. Epub 2013 Jul 4.

PMID:
23831062
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Autocrine amplification of integrin αIIbβ3 activation and platelet adhesive responses by deoxyribose-1-phosphate.

Vara DS, Campanella M, Canobbio I, Dunn WB, Pizzorno G, Hirano M, Pula G.

Thromb Haemost. 2013 Jun;109(6):1108-19. doi: 10.1160/TH12-10-0751. Epub 2013 Mar 14.

PMID:
23494007
[PubMed - indexed for MEDLINE]
9.

A community-driven global reconstruction of human metabolism.

Thiele I, Swainston N, Fleming RM, Hoppe A, Sahoo S, Aurich MK, Haraldsdottir H, Mo ML, Rolfsson O, Stobbe MD, Thorleifsson SG, Agren R, Bölling C, Bordel S, Chavali AK, Dobson P, Dunn WB, Endler L, Hala D, Hucka M, Hull D, Jameson D, Jamshidi N, Jonsson JJ, Juty N, Keating S, Nookaew I, Le Novère N, Malys N, Mazein A, Papin JA, Price ND, Selkov E Sr, Sigurdsson MI, Simeonidis E, Sonnenschein N, Smallbone K, Sorokin A, van Beek JH, Weichart D, Goryanin I, Nielsen J, Westerhoff HV, Kell DB, Mendes P, Palsson BØ.

Nat Biotechnol. 2013 May;31(5):419-25. doi: 10.1038/nbt.2488. Epub 2013 Mar 3.

PMID:
23455439
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

CASMI-The Small Molecule Identification Process from a Birmingham Perspective.

Allwood JW, Weber RJ, Zhou J, He S, Viant MR, Dunn WB.

Metabolites. 2013 May 21;3(2):397-411. doi: 10.3390/metabo3020397.

PMID:
24957998
[PubMed]
Free PMC Article
11.

Liquid chromatography-mass spectrometry calibration transfer and metabolomics data fusion.

Vaughan AA, Dunn WB, Allwood JW, Wedge DC, Blackhall FH, Whetton AD, Dive C, Goodacre R.

Anal Chem. 2012 Nov 20;84(22):9848-57. doi: 10.1021/ac302227c. Epub 2012 Oct 29.

PMID:
23072438
[PubMed - indexed for MEDLINE]
12.

The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans.

Dunn WB, Wilson ID, Nicholls AW, Broadhurst D.

Bioanalysis. 2012 Sep;4(18):2249-64. doi: 10.4155/bio.12.204. Review.

PMID:
23046267
[PubMed - indexed for MEDLINE]
13.

Dupuytren's disease metabolite analyses reveals alterations following initial short-term fibroblast culturing.

Rehman S, Xu Y, Dunn WB, Day PJ, Westerhoff HV, Goodacre R, Bayat A.

Mol Biosyst. 2012 Sep;8(9):2274-88. Epub 2012 Jul 6.

PMID:
22772395
[PubMed - indexed for MEDLINE]
14.

Fingerprinting food: current technologies for the detection of food adulteration and contamination.

Ellis DI, Brewster VL, Dunn WB, Allwood JW, Golovanov AP, Goodacre R.

Chem Soc Rev. 2012 Sep 7;41(17):5706-27. doi: 10.1039/c2cs35138b. Epub 2012 Jun 25. Review.

PMID:
22729179
[PubMed - indexed for MEDLINE]
15.

Improving metabolic flux predictions using absolute gene expression data.

Lee D, Smallbone K, Dunn WB, Murabito E, Winder CL, Kell DB, Mendes P, Swainston N.

BMC Syst Biol. 2012 Jun 19;6:73. doi: 10.1186/1752-0509-6-73.

PMID:
22713172
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA).

Ugarte M, Brown M, Hollywood KA, Cooper GJ, Bishop PN, Dunn WB.

Genome Med. 2012 Apr 30;4(4):35.

PMID:
22546713
[PubMed]
Free PMC Article
17.

A metabolomic approach identifies differences in maternal serum in third trimester pregnancies that end in poor perinatal outcome.

Heazell AE, Bernatavicius G, Warrander L, Brown MC, Dunn WB.

Reprod Sci. 2012 Aug;19(8):863-75. doi: 10.1177/1933719112438446. Epub 2012 Apr 24.

PMID:
22534329
[PubMed - indexed for MEDLINE]
18.

Short- and long-term dynamic responses of the metabolic network and gene expression in yeast to a transient change in the nutrient environment.

Dikicioglu D, Dunn WB, Kell DB, Kirdar B, Oliver SG.

Mol Biosyst. 2012 Jun;8(6):1760-74. doi: 10.1039/c2mb05443d. Epub 2012 Apr 11.

PMID:
22491778
[PubMed - indexed for MEDLINE]
19.

Proof-of-principle study to detect metabolic changes in peritoneal dialysis effluent in patients who develop encapsulating peritoneal sclerosis.

Dunn WB, Summers A, Brown M, Goodacre R, Lambie M, Johnson T, Wilkie M, Davies S, Topley N, Brenchley P.

Nephrol Dial Transplant. 2012 Jun;27(6):2502-10. doi: 10.1093/ndt/gfr662. Epub 2012 Jan 31.

PMID:
22294777
[PubMed - indexed for MEDLINE]
Free Article
20.

Integration of metabolomics in heart disease and diabetes research: current achievements and future outlook.

Dunn WB, Goodacre R, Neyses L, Mamas M.

Bioanalysis. 2011 Oct;3(19):2205-22. doi: 10.4155/bio.11.223. Review.

PMID:
21985415
[PubMed - indexed for MEDLINE]

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