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Carbohydrate and fatty acid perturbations in the amniotic fluid of the recipient twin of pregnancies complicated by twin-twin transfusion syndrome in relation to treatment and fetal cardiovascular risk.

Dunn WB, Allwood JW, Van Mieghem T, Morris RK, Mackie FL, Fox CE, Kilby MD.

Placenta. 2016 Aug;44:6-12. doi: 10.1016/j.placenta.2016.05.012. Epub 2016 May 27.


Characterisation of the metabolome of ocular tissues and post-mortem changes in the rat retina.

Tan SZ, Mullard G, Hollywood KA, Dunn WB, Bishop PN.

Exp Eye Res. 2016 May 24;149:8-15. doi: 10.1016/j.exer.2016.05.019. [Epub ahead of print]


Non-targeted UHPLC-MS metabolomic data processing methods: a comparative investigation of normalisation, missing value imputation, transformation and scaling.

Di Guida R, Engel J, Allwood JW, Weber RJ, Jones MR, Sommer U, Viant MR, Dunn WB.

Metabolomics. 2016;12:93. Epub 2016 Apr 15.


Metabolites involved in glycolysis and amino acid metabolism are altered in short children born small for gestational age.

Murray PG, Butcher I, Dunn WB, Stevens A, Perchard R, Hanson D, Whatmore A, Westwood M, Clayton PE.

Pediatr Res. 2016 Apr 8. doi: 10.1038/pr.2016.72. [Epub ahead of print]


Metabolomics reveals the physiological response of Pseudomonas putida KT2440 (UWC1) after pharmaceutical exposure.

Currie F, Broadhurst DI, Dunn WB, Sellick CA, Goodacre R.

Mol Biosyst. 2016 Apr;12(4):1367-77. doi: 10.1039/c5mb00889a. Epub 2016 Mar 2.


Cryptococcal 3-Hydroxy Fatty Acids Protect Cells Against Amoebal Phagocytosis.

Madu UL, Ogundeji AO, Mochochoko BM, Pohl CH, Albertyn J, Swart CW, Allwood JW, Southam AD, Dunn WB, May RC, Sebolai OM.

Front Microbiol. 2015 Dec 9;6:1351. doi: 10.3389/fmicb.2015.01351. eCollection 2015.


Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man.

Hazlehurst JM, Oprescu AI, Nikolaou N, Di Guida R, Grinbergs AE, Davies NP, Flintham RB, Armstrong MJ, Taylor AE, Hughes BA, Yu J, Hodson L, Dunn WB, Tomlinson JW.

J Clin Endocrinol Metab. 2016 Jan;101(1):103-13. doi: 10.1210/jc.2015-2928. Epub 2015 Nov 17.


In Reply.

Dunn WB, Boeing H.

Clin Chem. 2015 Dec;61(12):1544-6. doi: 10.1373/clinchem.2015.246843. Epub 2015 Nov 9. No abstract available.


Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells.

Armitage EG, Kotze HL, Allwood JW, Dunn WB, Goodacre R, Williams KJ.

Sci Rep. 2015 Oct 28;5:15649. doi: 10.1038/srep15649.


Alterations in bone marrow metabolism are an early and consistent feature during the development of MGUS and multiple myeloma.

Ludwig C, Williams DS, Bartlett DB, Essex SJ, McNee G, Allwood JW, Jewell E, Barkhuisen A, Parry H, Anandram S, Nicolson P, Gardener C, Seymour F, Basu S, Dunn WB, Moss PA, Pratt G, Tennant DA.

Blood Cancer J. 2015 Oct 16;5:e359. doi: 10.1038/bcj.2015.85. No abstract available.


Metabolic Dysfunction Is Restricted to the Sciatic Nerve in Experimental Diabetic Neuropathy.

Freeman OJ, Unwin RD, Dowsey AW, Begley P, Ali S, Hollywood KA, Rustogi N, Petersen RS, Dunn WB, Cooper GJ, Gardiner NJ.

Diabetes. 2016 Jan;65(1):228-38. doi: 10.2337/db15-0835. Epub 2015 Oct 15.


Training needs in metabolomics.

Weber RJ, Winder CL, Larcombe LD, Dunn WB, Viant MR.

Metabolomics. 2015;11(4):784-786. Epub 2015 May 29. No abstract available.


Exploring the mode of action of dithranol therapy for psoriasis: a metabolomic analysis using HaCaT cells.

Hollywood KA, Winder CL, Dunn WB, Xu Y, Broadhurst D, Griffiths CE, Goodacre R.

Mol Biosyst. 2015 Aug;11(8):2198-209. doi: 10.1039/c4mb00739e.


Antiphospholipid Antibodies Alter Cell-Death-Regulating Lipid Metabolites in First and Third Trimester Human Placentae.

Pantham P, Heazell AE, Mullard G, Begley P, Chen Q, Brown M, Dunn WB, Chamley LW.

Am J Reprod Immunol. 2015 Aug;74(2):181-99. doi: 10.1111/aji.12387. Epub 2015 Apr 9.


Profiling of spatial metabolite distributions in wheat leaves under normal and nitrate limiting conditions.

Allwood JW, Chandra S, Xu Y, Dunn WB, Correa E, Hopkins L, Goodacre R, Tobin AK, Bowsher CG.

Phytochemistry. 2015 Jul;115:99-111. doi: 10.1016/j.phytochem.2015.01.007. Epub 2015 Feb 10.


Molecular phenotyping of a UK population: defining the human serum metabolome.

Dunn WB, Lin W, Broadhurst D, Begley P, Brown M, Zelena E, Vaughan AA, Halsall A, Harding N, Knowles JD, Francis-McIntyre S, Tseng A, Ellis DI, O'Hagan S, Aarons G, Benjamin B, Chew-Graham S, Moseley C, Potter P, Winder CL, Potts C, Thornton P, McWhirter C, Zubair M, Pan M, Burns A, Cruickshank JK, Jayson GC, Purandare N, Wu FC, Finn JD, Haselden JN, Nicholls AW, Wilson ID, Goodacre R, Kell DB.

Metabolomics. 2015;11:9-26. Epub 2014 Jul 25.


Untargeted metabolic profiling identifies altered serum metabolites of type 2 diabetes mellitus in a prospective, nested case control study.

Drogan D, Dunn WB, Lin W, Buijsse B, Schulze MB, Langenberg C, Brown M, Floegel A, Dietrich S, Rolandsson O, Wedge DC, Goodacre R, Forouhi NG, Sharp SJ, Spranger J, Wareham NJ, Boeing H.

Clin Chem. 2015 Mar;61(3):487-97. doi: 10.1373/clinchem.2014.228965. Epub 2014 Dec 18.


Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy.

Gehmlich K, Dodd MS, Allwood JW, Kelly M, Bellahcene M, Lad HV, Stockenhuber A, Hooper C, Ashrafian H, Redwood CS, Carrier L, Dunn WB.

Mol Biosyst. 2015 Feb;11(2):564-73. doi: 10.1039/c4mb00594e.


MUSCLE: automated multi-objective evolutionary optimization of targeted LC-MS/MS analysis.

Bradbury J, Genta-Jouve G, Allwood JW, Dunn WB, Goodacre R, Knowles JD, He S, Viant MR.

Bioinformatics. 2015 Mar 15;31(6):975-7. doi: 10.1093/bioinformatics/btu740. Epub 2014 Nov 11.


Evidence that multiple defects in lipid regulation occur before hyperglycemia during the prodrome of type-2 diabetes.

Anderson SG, Dunn WB, Banerjee M, Brown M, Broadhurst DI, Goodacre R, Cooper GJ, Kell DB, Cruickshank JK.

PLoS One. 2014 Sep 3;9(9):e103217. doi: 10.1371/journal.pone.0103217. eCollection 2014.

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