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Simple and effective exercise design for assessing in vivo mitochondrial function in clinical applications using (31)P magnetic resonance spectroscopy.

Sleigh A, Lupson V, Thankamony A, Dunger DB, Savage DB, Carpenter TA, Kemp GJ.

Sci Rep. 2016 Jan 11;6:19057. doi: 10.1038/srep19057.


Day-and-Night Hybrid Closed-Loop Insulin Delivery in Adolescents With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial.

Tauschmann M, Allen JM, Wilinska ME, Thabit H, Stewart Z, Cheng P, Kollman C, Acerini CL, Dunger DB, Hovorka R.

Diabetes Care. 2016 Jan 6. pii: dc152078. [Epub ahead of print]


Cohort Profile: the Cambridge Baby Growth Study (CBGS).

Prentice P, Acerini CL, Eleftheriou A, Hughes IA, Ong KK, Dunger DB.

Int J Epidemiol. 2015 Dec 31. pii: dyv318. [Epub ahead of print] No abstract available.


Normal Variation in Pubertal Timing: Genetic Determinants in Relation to Growth and Adiposity.

Willemsen RH, Dunger DB.

Endocr Dev. 2016;29:17-35. doi: 10.1159/000438957. Epub 2015 Dec 17.


Adiposity in Children Born Small for Gestational Age Is Associated With β-Cell Function, Genetic Variants for Insulin Resistance, and Response to Growth Hormone Treatment.

Thankamony A, Jensen RB, O'Connell SM, Day F, Kirk J, Donaldson M, Ivarsson SA, Söder O, Roche E, Hoey H, Ong KK, Dunger DB, Juul A.

J Clin Endocrinol Metab. 2016 Jan;101(1):131-42. doi: 10.1210/jc.2015-3019. Epub 2015 Nov 20.


Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes.

Tauschmann M, Thabit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska ME, Heller SR, Amiel SA, Evans ML, Dunger DB, Hovorka R.

J Diabetes Sci Technol. 2015 Oct 7;9(6):1346-7. doi: 10.1177/1932296815604439. No abstract available.


Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults.

De Lucia Rolfe E, Ong KK, Sleigh A, Dunger DB, Norris SA.

BMC Public Health. 2015 Oct 5;15:1013. doi: 10.1186/s12889-015-2147-x.


Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.

Day FR, Hinds DA, Tung JY, Stolk L, Styrkarsdottir U, Saxena R, Bjonnes A, Broer L, Dunger DB, Halldorsson BV, Lawlor DA, Laval G, Mathieson I, McCardle WL, Louwers Y, Meun C, Ring S, Scott RA, Sulem P, Uitterlinden AG, Wareham NJ, Thorsteinsdottir U, Welt C, Stefansson K, Laven JS, Ong KK, Perry JR.

Nat Commun. 2015 Sep 29;6:8464. doi: 10.1038/ncomms9464.


Home Use of an Artificial Beta Cell in Type 1 Diabetes.

Thabit H, Tauschmann M, Allen JM, Leelarathna L, Hartnell S, Wilinska ME, Acerini CL, Dellweg S, Benesch C, Heinemann L, Mader JK, Holzer M, Kojzar H, Exall J, Yong J, Pichierri J, Barnard KD, Kollman C, Cheng P, Hindmarsh PC, Campbell FM, Arnolds S, Pieber TR, Evans ML, Dunger DB, Hovorka R; APCam Consortium; AP@home Consortium.

N Engl J Med. 2015 Nov 26;373(22):2129-40. doi: 10.1056/NEJMoa1509351. Epub 2015 Sep 17.


Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63:3835-3845.

Arif S, Leete P, Nguyen V, Marks K, Nor NM, Estorninho M, Kronenberg-Versteeg D, Bingley PJ, Todd JA, Guy C, Dunger DB, Powrie J, Willcox A, Foulis AK, Richardson SJ, de Rinaldis E, Morgan NG, Lorenc A, Peakman M.

Diabetes. 2015 Sep;64(9):3334. doi: 10.2337/db15-er09a. No abstract available.


Safety, efficacy and glucose turnover of reduced prandial boluses during closed-loop therapy in adolescents with type 1 diabetes: a randomized clinical trial.

Elleri D, Biagioni M, Allen JM, Kumareswaran K, Leelarathna L, Caldwell K, Nodale M, Wilinska ME, Haidar A, Calhoun P, Kollman C, Jackson NC, Umpleby AM, Acerini CL, Dunger DB, Hovorka R.

Diabetes Obes Metab. 2015 Dec;17(12):1173-9. doi: 10.1111/dom.12549. Epub 2015 Oct 9.


Biomarkers of rapid chronic kidney disease progression in type 2 diabetes.

Looker HC, Colombo M, Hess S, Brosnan MJ, Farran B, Dalton RN, Wong MC, Turner C, Palmer CN, Nogoceke E, Groop L, Salomaa V, Dunger DB, Agakov F, McKeigue PM, Colhoun HM; SUMMIT Investigators.

Kidney Int. 2015 Oct;88(4):888-96. doi: 10.1038/ki.2015.199. Epub 2015 Jul 22.


Age at Weaning and Infant Growth: Primary Analysis and Systematic Review.

Vail B, Prentice P, Dunger DB, Hughes IA, Acerini CL, Ong KK.

J Pediatr. 2015 Aug;167(2):317-24.e1. doi: 10.1016/j.jpeds.2015.05.003. Epub 2015 Jun 12. Review.


Even transient rapid infancy weight gain is associated with higher BMI in young adults and earlier menarche.

Salgin B, Norris SA, Prentice P, Pettifor JM, Richter LM, Ong KK, Dunger DB.

Int J Obes (Lond). 2015 Jun;39(6):939-44. doi: 10.1038/ijo.2015.25. Epub 2015 Mar 16.


IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.

Ferreira RC, Simons HZ, Thompson WS, Cutler AJ, Dopico XC, Smyth DJ, Mashar M, Schuilenburg H, Walker NM, Dunger DB, Wallace C, Todd JA, Wicker LS, Pekalski ML.

Diabetologia. 2015 Apr;58(4):781-90. doi: 10.1007/s00125-015-3509-8. Epub 2015 Feb 6.


Postnatal penile growth concurrent with mini-puberty predicts later sex-typed play behavior: Evidence for neurobehavioral effects of the postnatal androgen surge in typically developing boys.

Pasterski V, Acerini CL, Dunger DB, Ong KK, Hughes IA, Thankamony A, Hines M.

Horm Behav. 2015 Mar;69:98-105. doi: 10.1016/j.yhbeh.2015.01.002. Epub 2015 Jan 15.


Serum uric acid and cardiovascular risk among Portuguese adolescents.

Gonçalves JP, Ramos E, Severo M, Wong MC, Ong KK, Dunger DB, Lopes C.

J Adolesc Health. 2015 Apr;56(4):376-81. doi: 10.1016/j.jadohealth.2014.11.010. Epub 2015 Jan 10.


Cardiac autonomic dysfunction is associated with high-risk albumin-to-creatinine ratio in young adolescents with type 1 diabetes in AdDIT (adolescent type 1 diabetes cardio-renal interventional trial).

Cho YH, Craig ME, Davis EA, Cotterill AM, Couper JJ, Cameron FJ, Benitez-Aguirre PZ, Dalton RN, Dunger DB, Jones TW, Donaghue KC; Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial.

Diabetes Care. 2015 Apr;38(4):676-81. doi: 10.2337/dc14-1848. Epub 2015 Jan 8.


Pharmacokinetics of diluted (U20) insulin aspart compared with standard (U100) in children aged 3-6 years with type 1 diabetes during closed-loop insulin delivery: a randomised clinical trial.

Ruan Y, Elleri D, Allen JM, Tauschmann M, Wilinska ME, Dunger DB, Hovorka R.

Diabetologia. 2015 Apr;58(4):687-90. doi: 10.1007/s00125-014-3483-6. Epub 2014 Dec 24.


Feasibility of overnight closed-loop therapy in young children with type 1 diabetes aged 3-6 years: comparison between diluted and standard insulin strength.

Elleri D, Allen JM, Tauschmann M, El-Khairi R, Benitez-Aguirre P, Acerini CL, Dunger DB, Hovorka R.

BMJ Open Diabetes Res Care. 2014 Dec 11;2(1):e000040. doi: 10.1136/bmjdrc-2014-000040. eCollection 2014.

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