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Plasmin and regulators of plasmin activity control the migratory capacity and adhesion of human T cells and dendritic cells by regulating cleavage of the chemokine CCL21.

Lorenz N, Loef EJ, Kelch ID, Verdon DJ, Black MM, Middleditch MJ, Greenwood DR, Graham ES, Brooks AE, Dunbar PR, Birch NP.

Immunol Cell Biol. 2016 Jun 15. doi: 10.1038/icb.2016.56. [Epub ahead of print]


Cultured pericytes from human brain show phenotypic and functional differences associated with differential CD90 expression.

Park TI, Feisst V, Brooks AE, Rustenhoven J, Monzo HJ, Feng SX, Mee EW, Bergin PS, Oldfield R, Graham ES, Curtis MA, Faull RL, Dunbar PR, Dragunow M.

Sci Rep. 2016 May 24;6:26587. doi: 10.1038/srep26587.


A multi-laboratory comparison of blood dendritic cell populations.

Fromm PD, Kupresanin F, Brooks AE, Dunbar PR, Haniffa M, Hart DN, Clark GJ.

Clin Transl Immunology. 2016 Apr 8;5(4):e68. doi: 10.1038/cti.2016.5. eCollection 2016 Apr.


New insights into the phenotype of human dendritic cell populations.

Clark GJ, Kupresanin F, Fromm PD, Ju X, Muusers L, Silveira PA, Elgundi Z, Gasiorowski RE, Papadimitrious MS, Bryant C, Lee KM, Clarke CJ, Young JW, Chan A, Harman A, Botting R, Cabezón R, Benitez-Ribas D, Brooks AE, Dunbar PR, Hart DN.

Clin Transl Immunology. 2016 Jan 29;5(1):e61. doi: 10.1038/cti.2015.40. eCollection 2016 Jan.


Corrigendum: Organ-wide 3D-imaging and topological analysis of the continuous microvascular network in a murine lymph node.

Kelch ID, Bogle G, Sands GB, Phillips AR, LeGrice IJ, Dunbar PR.

Sci Rep. 2016 Feb 4;6:20294. doi: 10.1038/srep20294. No abstract available.


High level expression and purification of active recombinant human interleukin-15 in Pichia pastoris.

Sun W, Lai Y, Li H, Nie T, Kuang Y, Tang X, Li K, Dunbar PR, Xu A, Li P, Wu D.

J Immunol Methods. 2016 Jan;428:50-7. doi: 10.1016/j.jim.2015.12.002. Epub 2015 Dec 8.


Spatially transformed fluorescence image data for ERK-MAPK and selected proteins within human epidermis.

Cursons J, Angel CE, Hurley DG, Print CG, Dunbar PR, Jacobs MD, Crampin EJ.

Gigascience. 2015 Dec 14;4:63. doi: 10.1186/s13742-015-0102-5. eCollection 2015.


AHNAK is downregulated in melanoma, predicts poor outcome, and may be required for the expression of functional cadherin-1.

Sheppard HM, Feisst V, Chen J, Print C, Dunbar PR.

Melanoma Res. 2016 Apr;26(2):108-16. doi: 10.1097/CMR.0000000000000228.


Trauma, Critical Care, and Emergency Care Anesthesiology: A New Paradigm for the "Acute Care" Anesthesiologist?

McCunn M, Dutton RP, Dagal A, Varon AJ, Kaslow O, Kucik CJ, Hagberg CA, McIsaac JH 3rd, Pittet JF, Dunbar PJ, Grissom T, Vavilala MS.

Anesth Analg. 2015 Dec;121(6):1668-73. doi: 10.1213/ANE.0000000000000782. Review. No abstract available.


Organ-wide 3D-imaging and topological analysis of the continuous microvascular network in a murine lymph node.

Kelch ID, Bogle G, Sands GB, Phillips AR, LeGrice IJ, Dunbar PR.

Sci Rep. 2015 Nov 16;5:16534. doi: 10.1038/srep16534.


Augmentation with an ovine forestomach matrix scaffold improves histological outcomes of rotator cuff repair in a rat model.

Street M, Thambyah A, Dray M, Amirapu S, Tuari D, Callon KE, McIntosh JD, Burkert K, Dunbar PR, Coleman B, Cornish J, Musson DS.

J Orthop Surg Res. 2015 Oct 20;10:165. doi: 10.1186/s13018-015-0303-8.


Regulation of ERK-MAPK signaling in human epidermis.

Cursons J, Gao J, Hurley DG, Print CG, Dunbar PR, Jacobs MD, Crampin EJ.

BMC Syst Biol. 2015 Jul 25;9:41. doi: 10.1186/s12918-015-0187-6.


Cell-targeted platinum nanoparticles and nanoparticle clusters.

Papst S, Brimble MA, Evans CW, Verdon DJ, Feisst V, Dunbar PR, Tilley RD, Williams DE.

Org Biomol Chem. 2015 Jun 21;13(23):6567-72. doi: 10.1039/c5ob00822k. Epub 2015 May 15.


Species-specific differences in the expression and regulation of α4β7 integrin in various nonhuman primates.

Byrareddy SN, Sidell N, Arthos J, Cicala C, Zhao C, Little DM, Dunbar P, Yang GX, Pierzchalski K, Kane MA, Mayne AE, Song B, Soares MA, Villinger F, Fauci AS, Ansari AA.

J Immunol. 2015 Jun 15;194(12):5968-79. doi: 10.4049/jimmunol.1402866. Epub 2015 May 6.


Human T cell activation induces synaptic translocation and alters expression of the serine protease inhibitor neuroserpin and its target protease.

Lorenz N, Loef EJ, Verdon DJ, Chen CJ, Mansell CJ, Angel CE, Brooks AE, Dunbar PR, Birch NP.

J Leukoc Biol. 2015 Apr;97(4):699-710. doi: 10.1189/jlb.1A0814-392R. Epub 2015 Feb 10.


In vitro evaluation of a novel non-mulberry silk scaffold for use in tendon regeneration.

Musson DS, Naot D, Chhana A, Matthews BG, McIntosh JD, Lin ST, Choi AJ, Callon KE, Dunbar PR, Lesage S, Coleman B, Cornish J.

Tissue Eng Part A. 2015 May;21(9-10):1539-51. doi: 10.1089/ten.TEA.2014.0128. Epub 2015 Mar 10.


Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection.

Byrareddy SN, Kallam B, Arthos J, Cicala C, Nawaz F, Hiatt J, Kersh EN, McNicholl JM, Hanson D, Reimann KA, Brameier M, Walter L, Rogers K, Mayne AE, Dunbar P, Villinger T, Little D, Parslow TG, Santangelo PJ, Villinger F, Fauci AS, Ansari AA.

Nat Med. 2014 Dec;20(12):1397-400. doi: 10.1038/nm.3715. Epub 2014 Nov 24.


Blocking αVβ3 integrin ligand occupancy inhibits the progression of albuminuria in diabetic rats.

Maile LA, Gollahon K, Wai C, Dunbar P, Busby W, Clemmons D.

J Diabetes Res. 2014;2014:421827. doi: 10.1155/2014/421827. Epub 2014 Oct 20.


MicroRNA regulation in human CD8+ T cell subsets--cytokine exposure alone drives miR-146a expression.

Sheppard HM, Verdon D, Brooks AE, Feisst V, Ho YY, Lorenz N, Fan V, Birch NP, Didsbury A, Dunbar PR.

J Transl Med. 2014 Oct 21;12:292. doi: 10.1186/s12967-014-0292-0.


The immunophenotype of antigen presenting cells of the mononuclear phagocyte system in normal human liver--a systematic review.

Strauss O, Dunbar PR, Bartlett A, Phillips A.

J Hepatol. 2015 Feb;62(2):458-68. doi: 10.1016/j.jhep.2014.10.006. Epub 2014 Oct 12. Review.

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