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A simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer.

Lazar V, Rubin E, Depil S, Pawitan Y, Martini JF, Gomez-Navarro J, Yver A, Kan Z, Dry JR, Kehren J, Validire P, Rodon J, Vielh P, Ducreux M, Galbraith S, Lehnert M, Onn A, Berger R, Pierotti MA, Porgador A, Pramesh CS, Ye DW, Carvalho AL, Batist G, Le Chevalier T, Morice P, Besse B, Vassal G, Mortlock A, Hansson J, Berindan-Neagoe I, Dann R, Haspel J, Irimie A, Laderman S, Nechushtan H, Al Omari AS, Haywood T, Bresson C, Soo KC, Osman I, Mata H, Lee JJ, Jhaveri K, Meurice G, Palmer G, Lacroix L, Koscielny S, Eterovic KA, Blay JY, Buller R, Eggermont A, Schilsky RL, Mendelsohn J, Soria JC, Rothenberg M, Scoazec JY, Hong WK, Kurzrock R.

Oncotarget. 2015 Jun 10;6(16):14139-52.


Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models.

Eberlein CA, Stetson D, Markovets AA, Al-Kadhimi KJ, Lai Z, Fisher PR, Meador CB, Spitzler P, Ichihara E, Ross SJ, Ahdesmaki MJ, Ahmed A, Ratcliffe LE, O'Brien EL, Barnes CH, Brown H, Smith PD, Dry JR, Beran G, Thress KS, Dougherty B, Pao W, Cross DA.

Cancer Res. 2015 Jun 15;75(12):2489-500. doi: 10.1158/0008-5472.CAN-14-3167. Epub 2015 Apr 13.


Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients.

Guinney J, Ferté C, Dry J, McEwen R, Manceau G, Kao KJ, Chang KM, Bendtsen C, Hudson K, Huang E, Dougherty B, Ducreux M, Soria JC, Friend S, Derry J, Laurent-Puig P.

Clin Cancer Res. 2014 Jan 1;20(1):265-72. doi: 10.1158/1078-0432.CCR-13-1943. Epub 2013 Oct 29.


RNA-Seq Differentiates Tumour and Host mRNA Expression Changes Induced by Treatment of Human Tumour Xenografts with the VEGFR Tyrosine Kinase Inhibitor Cediranib.

Bradford JR, Farren M, Powell SJ, Runswick S, Weston SL, Brown H, Delpuech O, Wappett M, Smith NR, Carr TH, Dry JR, Gibson NJ, Barry ST.

PLoS One. 2013 Jun 19;8(6):e66003. Print 2013.


Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: associations of maternal A1C and glucose with pregnancy outcomes.

Lowe LP, Metzger BE, Dyer AR, Lowe J, McCance DR, Lappin TR, Trimble ER, Coustan DR, Hadden DR, Hod M, Oats JJ, Persson B; HAPO Study Cooperative Research Group.

Diabetes Care. 2012 Mar;35(3):574-80. doi: 10.2337/dc11-1687. Epub 2012 Feb 1.


A 29-year old woman presenting with abdominal pain and vomiting.

DiBuono B, Ferrante WA, Weed T, Vargas RD, Dry JK, Carter CF, Lopez FA.

J La State Med Soc. 2011 Jan-Feb;163(1):11-8. Review. No abstract available.


Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells.

Little AS, Balmanno K, Sale MJ, Newman S, Dry JR, Hampson M, Edwards PA, Smith PD, Cook SJ.

Sci Signal. 2011 Mar 29;4(166):ra17. doi: 10.1126/scisignal.2001752. Erratum in: Sci Signal. 2011;4(170). doi:10.1126/scisignal.4170er2. Corrected and republished in: Sci Signal. 2011;4(170):er2.


Benefits of mTOR kinase targeting in oncology: pre-clinical evidence with AZD8055.

Marshall G, Howard Z, Dry J, Fenton S, Heathcote D, Gray N, Keen H, Logie A, Holt S, Smith P, Guichard SM.

Biochem Soc Trans. 2011 Apr;39(2):456-9. doi: 10.1042/BST0390456. Review.


Hyperglycemia and adverse pregnancy outcome study: neonatal glycemia.

Metzger BE, Persson B, Lowe LP, Dyer AR, Cruickshank JK, Deerochanawong C, Halliday HL, Hennis AJ, Liley H, Ng PC, Coustan DR, Hadden DR, Hod M, Oats JJ, Trimble ER; HAPO Study Cooperative Research Group.

Pediatrics. 2010 Dec;126(6):e1545-52. doi: 10.1542/peds.2009-2257. Epub 2010 Nov 15.


Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244).

Dry JR, Pavey S, Pratilas CA, Harbron C, Runswick S, Hodgson D, Chresta C, McCormack R, Byrne N, Cockerill M, Graham A, Beran G, Cassidy A, Haggerty C, Brown H, Ellison G, Dering J, Taylor BS, Stark M, Bonazzi V, Ravishankar S, Packer L, Xing F, Solit DB, Finn RS, Rosen N, Hayward NK, French T, Smith PD.

Cancer Res. 2010 Mar 15;70(6):2264-73. doi: 10.1158/0008-5472.CAN-09-1577. Epub 2010 Mar 9.


Hyperglycemia and adverse pregnancy outcomes.

HAPO Study Cooperative Research Group, Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, Coustan DR, Hadden DR, McCance DR, Hod M, McIntyre HD, Oats JJ, Persson B, Rogers MS, Sacks DA.

N Engl J Med. 2008 May 8;358(19):1991-2002. doi: 10.1056/NEJMoa0707943.


A bio-basis function neural network for protein peptide cleavage activity characterisation.

Yang ZR, Dry J, Thomson R, Charles Hodgman T.

Neural Netw. 2006 May;19(4):401-7. Epub 2006 Feb 14.


Preliminary evaluation of a cervical self-sampling device with liquid-based cytology and multiparameter molecular testing.

Knesel BW, Dry JC, Wald-Scott C, Aftab A.

J Reprod Med. 2005 Apr;50(4):256-60. Erratum in: J Reprod Med. 2005 May;50(5):376. Aftoh, Asma [corrected to Aftab, Asma].


Searching for discrimination rules in protease proteolytic cleavage activity using genetic programming with a min-max scoring function.

Yang ZR, Thomson R, Hodgman TC, Dry J, Doyle AK, Narayanan A, Wu X.

Biosystems. 2003 Nov;72(1-2):159-76.


Pathologic quiz case: post-lung transplantation patient with bilateral breast masses.

Zhang JW, Dry J, Moroz K.

Arch Pathol Lab Med. 2003 Mar;127(3):375-6. No abstract available.


Effects of acrivastine and terfenadine on skin reactivity to histamine.

Leynadier F, Murrieta M, Dry J, Colin JN, Gillotin C, Steru D.

Ann Allergy. 1994 Jun;72(6):520-4.


Intratracheal E. coli lipopolysaccharide induces platelet-dependent bronchial hyperreactivity.

Vincent D, Lefort J, Chatelet F, Bureau MF, Dry J, Vargaftig BB.

J Appl Physiol (1985). 1993 Mar;74(3):1027-38.

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