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Items: 11

1.

Blood-based identification of non-responders to anti-TNF therapy in rheumatoid arthritis.

Thomson TM, Lescarbeau RM, Drubin DA, Laifenfeld D, de Graaf D, Fryburg DA, Littman B, Deehan R, Van Hooser A.

BMC Med Genomics. 2015 Jun 3;8:26. doi: 10.1186/s12920-015-0100-6.

2.

Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks.

Martin F, Thomson TM, Sewer A, Drubin DA, Mathis C, Weisensee D, Pratt D, Hoeng J, Peitsch MC.

BMC Syst Biol. 2012 May 31;6:54. doi: 10.1186/1752-0509-6-54.

3.

Early patient stratification and predictive biomarkers in drug discovery and development: a case study of ulcerative colitis anti-TNF therapy.

Laifenfeld D, Drubin DA, Catlett NL, Park JS, Van Hooser AA, Frushour BP, de Graaf D, Fryburg DA, Deehan R.

Adv Exp Med Biol. 2012;736:645-53. doi: 10.1007/978-1-4419-7210-1_38.

PMID:
22161357
4.

A network-based approach to quantifying the impact of biologically active substances.

Hoeng J, Deehan R, Pratt D, Martin F, Sewer A, Thomson TM, Drubin DA, Waters CA, de Graaf D, Peitsch MC.

Drug Discov Today. 2012 May;17(9-10):413-8. doi: 10.1016/j.drudis.2011.11.008. Epub 2011 Dec 2. No abstract available.

PMID:
22155224
5.

Rational design of memory in eukaryotic cells.

Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EP, Landgraf D, Phillips I, Silver PA.

Genes Dev. 2007 Sep 15;21(18):2271-6.

6.

Designing biological systems.

Drubin DA, Way JC, Silver PA.

Genes Dev. 2007 Feb 1;21(3):242-54. Review.

7.

The chloromethylketone protease inhibitor AAPF(CMK) also targets ATP-dependent helicases and SAP-domain proteins.

Dhamne C, Drubin DA, Duncan K, Tevethia MJ, Clawson GA.

J Cell Biochem. 2007 Feb 15;100(3):716-26.

PMID:
17006953
9.

A protease inhibitor specifically inhibits growth of HPV-infected keratinocytes.

Drubin DA, McLaughlin-Drubin ME, Clawson GA, Meyers C.

Mol Ther. 2006 Jun;13(6):1142-8. Epub 2006 Mar 27.

PMID:
16564747
10.

Developmentally induced changes in transcriptional program alter spatial organization across chromosomes.

Casolari JM, Brown CR, Drubin DA, Rando OJ, Silver PA.

Genes Dev. 2005 May 15;19(10):1188-98.

11.
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