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Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries.

Dreier R, Asferg C, Berg JO, Andersen UB, Flyvbjerg A, Frystyk J, Linneberg A, Jeppesen JL, Edvinsson L, Skovsted GF.

Basic Clin Pharmacol Toxicol. 2015 Aug 14. doi: 10.1111/bcpt.12452. [Epub ahead of print]


Sonic hedgehog processing and release are regulated by glypican heparan sulfate proteoglycans.

Ortmann C, Pickhinke U, Exner S, Ohlig S, Lawrence R, Jboor H, Dreier R, Grobe K.

J Cell Sci. 2015 Jun 15;128(12):2374-85. doi: 10.1242/jcs.170670. Epub 2015 May 12.


Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.

Meunier E, Wallet P, Dreier RF, Costanzo S, Anton L, Rühl S, Dussurgey S, Dick MS, Kistner A, Rigard M, Degrandi D, Pfeffer K, Yamamoto M, Henry T, Broz P.

Nat Immunol. 2015 May;16(5):476-84. doi: 10.1038/ni.3119. Epub 2015 Mar 16.


ER Stress During the Pubertal Growth Spurt Results in Impaired Long-Bone Growth in Chondrocyte-Specific ERp57 Knockout Mice.

Linz A, Knieper Y, Gronau T, Hansen U, Aszodi A, Garbi N, Hämmerling GJ, Pap T, Bruckner P, Dreier R.

J Bone Miner Res. 2015 Aug;30(8):1481-93. doi: 10.1002/jbmr.2484. Epub 2015 Jun 16.


Age of collagen in intracranial saccular aneurysms.

Etminan N, Dreier R, Buchholz BA, Beseoglu K, Bruckner P, Matzenauer C, Torner JC, Brown RD Jr, Steiger HJ, Hänggi D, Macdonald RL.

Stroke. 2014 Jun;45(6):1757-63. doi: 10.1161/STROKEAHA.114.005461. Epub 2014 Apr 29.


Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.

Meunier E, Dick MS, Dreier RF, Schürmann N, Kenzelmann Broz D, Warming S, Roose-Girma M, Bumann D, Kayagaki N, Takeda K, Yamamoto M, Broz P.

Nature. 2014 May 15;509(7500):366-70. doi: 10.1038/nature13157. Epub 2014 Apr 16.


Cerebral aneurysms: formation, progression, and developmental chronology.

Etminan N, Buchholz BA, Dreier R, Bruckner P, Torner JC, Steiger HJ, Hänggi D, Macdonald RL.

Transl Stroke Res. 2014 Apr;5(2):167-73. doi: 10.1007/s12975-013-0294-x. Epub 2013 Oct 30. Review.


Differences in the region- and depth-dependent microstructural organization in normal versus glaucomatous human posterior sclerae.

Danford FL, Yan D, Dreier RA, Cahir TM, Girkin CA, Vande Geest JP.

Invest Ophthalmol Vis Sci. 2013 Dec 3;54(13):7922-32. doi: 10.1167/iovs.13-12262.


Systems-level overview of host protein phosphorylation during Shigella flexneri infection revealed by phosphoproteomics.

Schmutz C, Ahrné E, Kasper CA, Tschon T, Sorg I, Dreier RF, Schmidt A, Arrieumerlou C.

Mol Cell Proteomics. 2013 Oct;12(10):2952-68. doi: 10.1074/mcp.M113.029918. Epub 2013 Jul 4.


Exploring the age of intracranial aneurysms using carbon birth dating: preliminary results.

Etminan N, Dreier R, Buchholz BA, Bruckner P, Steiger HJ, Hänggi D, Macdonald RL.

Stroke. 2013 Mar;44(3):799-802. doi: 10.1161/STROKEAHA.112.673806. Epub 2013 Jan 17.


Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice.

Bertrand J, Stange R, Hidding H, Echtermeyer F, Nalesso G, Godmann L, Timmen M, Bruckner P, Dell'Accio F, Raschke MJ, Pap T, Dreier R.

Arthritis Rheum. 2013 Mar;65(3):743-52. doi: 10.1002/art.37817.


An emerging role of Sonic hedgehog shedding as a modulator of heparan sulfate interactions.

Ohlig S, Pickhinke U, Sirko S, Bandari S, Hoffmann D, Dreier R, Farshi P, Götz M, Grobe K.

J Biol Chem. 2012 Dec 21;287(52):43708-19. doi: 10.1074/jbc.M112.356667. Epub 2012 Nov 1. Erratum in: J Biol Chem. 2013 Feb 15;288(7):5049.


Dances of Death: macabre mirrors of an unequal society.

Mackenbach JP, Dreier RP.

Int J Public Health. 2012 Dec;57(6):915-24. doi: 10.1007/s00038-012-0381-x. Epub 2012 Jun 15.


[Preserving life and limb on the stage of death: the Dance of Death by Dr Salomon van Rusting].

Dreier RP, Mackenbach JP.

Ned Tijdschr Geneeskd. 2012;156(10):A4079. Dutch.


Sonic hedgehog shedding results in functional activation of the solubilized protein.

Ohlig S, Farshi P, Pickhinke U, van den Boom J, Höing S, Jakuschev S, Hoffmann D, Dreier R, Schöler HR, Dierker T, Bordych C, Grobe K.

Dev Cell. 2011 Jun 14;20(6):764-74. doi: 10.1016/j.devcel.2011.05.010.


Dual roles of the Cardin-Weintraub motif in multimeric Sonic hedgehog.

Farshi P, Ohlig S, Pickhinke U, Höing S, Jochmann K, Lawrence R, Dreier R, Dierker T, Grobe K.

J Biol Chem. 2011 Jul 1;286(26):23608-19. doi: 10.1074/jbc.M110.206474. Epub 2011 May 13.


Interaction of periosteal explants with articular chondrocytes alters expression profile of matrix metalloproteinases.

Rickert M, Dreier R, Radons J, Opolka A, Grifka J, Anders S, Grässel S.

J Orthop Res. 2010 Dec;28(12):1576-85. doi: 10.1002/jor.21154.


Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders.

Dreier R.

Arthritis Res Ther. 2010;12(5):216. doi: 10.1186/ar3117. Epub 2010 Sep 16. Review.


Interleukin-1alpha treatment of meniscal explants stimulates the production and release of aggrecanase-generated, GAG-substituted aggrecan products and also the release of pre-formed, aggrecanase-generated G1 and m-calpain-generated G1-G2.

Lemke AK, Sandy JD, Voigt H, Dreier R, Lee JH, Grodzinsky AJ, Mentlein R, Fay J, Schünke M, Kurz B.

Cell Tissue Res. 2010 Apr;340(1):179-88. doi: 10.1007/s00441-010-0941-4. Epub 2010 Mar 9.


Heparan sulfate and transglutaminase activity are required for the formation of covalently cross-linked hedgehog oligomers.

Dierker T, Dreier R, Migone M, Hamer S, Grobe K.

J Biol Chem. 2009 Nov 20;284(47):32562-71. doi: 10.1074/jbc.M109.044867. Epub 2009 Sep 28.

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